N-phenylanthranilic acid-317 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the N-phenylanthranilic acid-317 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACACB acetyl-CoA carboxylase beta
ADAM12 ADAM metallopeptidase domain 12
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALG12 ALG12, alpha-1,6-mannosyltransferase
ASCL3 achaete-scute family bHLH transcription factor 3
C1ORF68 chromosome 1 open reading frame 68
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CAMKV CaM kinase-like vesicle-associated
CCL13 chemokine (C-C motif) ligand 13
CCL25 chemokine (C-C motif) ligand 25
CCNK cyclin K
CDC25A cell division cycle 25A
CDK10 cyclin-dependent kinase 10
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHRD chordin
CHRM4 cholinergic receptor, muscarinic 4
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLCN7 chloride channel, voltage-sensitive 7
COL6A1 collagen, type VI, alpha 1
COL6A3 collagen, type VI, alpha 3
COX4I1 cytochrome c oxidase subunit IV isoform 1
CRYAA crystallin, alpha A
DAPK2 death-associated protein kinase 2
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DHRS9 dehydrogenase/reductase (SDR family) member 9
EFR3B EFR3 homolog B (S. cerevisiae)
ELK1 ELK1, member of ETS oncogene family
FERMT1 fermitin family member 1
FGF2 fibroblast growth factor 2 (basic)
FKBP10 FK506 binding protein 10, 65 kDa
FUT2 fucosyltransferase 2 (secretor status included)
GAMT guanidinoacetate N-methyltransferase
GLG1 golgi glycoprotein 1
GNG13 guanine nucleotide binding protein (G protein), gamma 13
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2AB histone cluster 1, H2ab
HOXA10 homeobox A10
HRASLS2 HRAS-like suppressor 2
HRH1 histamine receptor H1
IFITM1 interferon induced transmembrane protein 1
IL11 interleukin 11
INE1 inactivation escape 1 (non-protein coding)
KLHL20 kelch-like family member 20
LRRN3 leucine rich repeat neuronal 3
MARC1 mitochondrial amidoxime reducing component 1
MAST3 microtubule associated serine/threonine kinase 3
MCHR1 melanin-concentrating hormone receptor 1
MCOLN1 mucolipin 1
MOCS1 molybdenum cofactor synthesis 1
MT4 metallothionein 4
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NCKAP1L NCK-associated protein 1-like
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NPTX1 neuronal pentraxin I
NPY neuropeptide Y
NXF2 nuclear RNA export factor 2
OPCML opioid binding protein/cell adhesion molecule-like
OPRK1 opioid receptor, kappa 1
OSBPL3 oxysterol binding protein-like 3
OVOL1 ovo-like zinc finger 1
PAX2 paired box 2
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PDE4DIP phosphodiesterase 4D interacting protein
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
RAP1GAP RAP1 GTPase activating protein
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RUNX2 runt-related transcription factor 2
SBNO1 strawberry notch homolog 1 (Drosophila)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SMAD3 SMAD family member 3
SOCS7 suppressor of cytokine signaling 7
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPON1 spondin 1, extracellular matrix protein
SPRY4 sprouty homolog 4 (Drosophila)
SPTBN2 spectrin, beta, non-erythrocytic 2
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
TCF3 transcription factor 3
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TPMT thiopurine S-methyltransferase
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TTC38 tetratricopeptide repeat domain 38
TTLL3 tubulin tyrosine ligase-like family member 3
TUBBP5 tubulin, beta pseudogene 5
VIPR2 vasoactive intestinal peptide receptor 2
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WIZ widely interspaced zinc finger motifs
ZNF419 zinc finger protein 419
ZNF460 zinc finger protein 460
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACAD10 acyl-CoA dehydrogenase family, member 10
ACTN3 actinin, alpha 3 (gene/pseudogene)
AMN amnion associated transmembrane protein
AMPH amphiphysin
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
CA11 carbonic anhydrase XI
CBX7 chromobox homolog 7
CCDC33 coiled-coil domain containing 33
CCDC64 coiled-coil domain containing 64
CCDC82 coiled-coil domain containing 82
CD38 CD38 molecule
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CLSTN2 calsyntenin 2
CRYBG3 beta-gamma crystallin domain containing 3
CRYGB crystallin, gamma B
CUBN cubilin (intrinsic factor-cobalamin receptor)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYSLTR2 cysteinyl leukotriene receptor 2
DEFB1 defensin, beta 1
DYSF dysferlin
EPX eosinophil peroxidase
F3 coagulation factor III (thromboplastin, tissue factor)
FOSL1 FOS-like antigen 1
FXYD7 FXYD domain containing ion transport regulator 7
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GRIP2 glutamate receptor interacting protein 2
GRM2 glutamate receptor, metabotropic 2
H2AFY2 H2A histone family, member Y2
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HDC histidine decarboxylase
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXA3 homeobox A3
HRH2 histamine receptor H2
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IKZF2 IKAROS family zinc finger 2 (Helios)
IQGAP2 IQ motif containing GTPase activating protein 2
ITK IL2-inducible T-cell kinase
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KIF18A kinesin family member 18A
KIFAP3 kinesin-associated protein 3
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KRT75 keratin 75, type II
LINC00574 long intergenic non-protein coding RNA 574
MC4R melanocortin 4 receptor
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MLXIPL MLX interacting protein-like
MMP8 matrix metallopeptidase 8
MTMR10 myotubularin related protein 10
MYO1F myosin IF
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NOTCH4 notch 4
NXPH4 neurexophilin 4
OLFML2A olfactomedin-like 2A
PDZD8 PDZ domain containing 8
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PRG3 proteoglycan 3
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PROL1 proline rich, lacrimal 1
PRSS2 protease, serine, 2 (trypsin 2)
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RAB3A RAB3A, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RCVRN recoverin
RECQL4 RecQ protein-like 4
RNF39 ring finger protein 39
SAG S-antigen; retina and pineal gland (arrestin)
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC38A3 solute carrier family 38, member 3
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLURP1 secreted LY6/PLAUR domain containing 1
T T, brachyury homolog (mouse)
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBR1 T-box, brain, 1
TMEM143 transmembrane protein 143
TMPRSS6 transmembrane protease, serine 6
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
UNC93B1 unc-93 homolog B1 (C. elegans)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR91 WD repeat domain 91
ZNF134 zinc finger protein 134
ZNF654 zinc finger protein 654
ZNF695 zinc finger protein 695
ZNHIT2 zinc finger, HIT-type containing 2