N-acetyl-L-aspartic acid-4007 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the N-acetyl-L-aspartic acid-4007 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
ANGEL2 angel homolog 2 (Drosophila)
APAF1 apoptotic peptidase activating factor 1
BBC3 BCL2 binding component 3
BCHE butyrylcholinesterase
BTN3A2 butyrophilin, subfamily 3, member A2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C1ORF159 chromosome 1 open reading frame 159
C1ORF54 chromosome 1 open reading frame 54
C1ORF95 chromosome 1 open reading frame 95
CA5A carbonic anhydrase VA, mitochondrial
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBS cystathionine-beta-synthase
CD58 CD58 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CES3 carboxylesterase 3
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COBL cordon-bleu WH2 repeat protein
CRY2 cryptochrome circadian clock 2
CYTH1 cytohesin 1
DCAF11 DDB1 and CUL4 associated factor 11
DGKE diacylglycerol kinase, epsilon 64kDa
DHODH dihydroorotate dehydrogenase (quinone)
DMRT1 doublesex and mab-3 related transcription factor 1
DOHH deoxyhypusine hydroxylase/monooxygenase
DST dystonin
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EDIL3 EGF-like repeats and discoidin I-like domains 3
EDRF1 erythroid differentiation regulatory factor 1
ETV1 ets variant 1
EXOC7 exocyst complex component 7
FAM105A family with sequence similarity 105, member A
FAS Fas cell surface death receptor
FBXO22 F-box protein 22
FGF14 fibroblast growth factor 14
FUBP1 far upstream element (FUSE) binding protein 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GSTCD glutathione S-transferase, C-terminal domain containing
HCFC1 host cell factor C1
HEMK1 HemK methyltransferase family member 1
HIST1H4C histone cluster 1, H4c
ICOSLG inducible T-cell co-stimulator ligand
IL12A interleukin 12A
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LIMK2 LIM domain kinase 2
MAGEA5 melanoma antigen family A5
MAP1B microtubule-associated protein 1B
MAP2K5 mitogen-activated protein kinase kinase 5
MDM4 MDM4, p53 regulator
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MST1L macrophage stimulating 1-like
MT3 metallothionein 3
MYO9B myosin IXB
NPR2 natriuretic peptide receptor 2
OAZ3 ornithine decarboxylase antizyme 3
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARP6 poly (ADP-ribose) polymerase family, member 6
PDGFA platelet-derived growth factor alpha polypeptide
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLCD1 phospholipase C, delta 1
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PRPH2 peripherin 2 (retinal degeneration, slow)
PTBP3 polypyrimidine tract binding protein 3
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PVR poliovirus receptor
REPS1 RALBP1 associated Eps domain containing 1
RNASEH2B ribonuclease H2, subunit B
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPA4 replication protein A4, 30kDa
RPL23AP32 ribosomal protein L23a pseudogene 32
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S1PR1 sphingosine-1-phosphate receptor 1
SCARB1 scavenger receptor class B, member 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SMAD4 SMAD family member 4
STK4 serine/threonine kinase 4
TADA2A transcriptional adaptor 2A
TBX2 T-box 2
TET3 tet methylcytosine dioxygenase 3
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
THBS3 thrombospondin 3
TJAP1 tight junction associated protein 1 (peripheral)
TLN2 talin 2
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMPRSS15 transmembrane protease, serine 15
TTC30A tetratricopeptide repeat domain 30A
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VPRBP Vpr (HIV-1) binding protein
WNK1 WNK lysine deficient protein kinase 1
ZBTB20 zinc finger and BTB domain containing 20
ZC2HC1C zinc finger, C2HC-type containing 1C
ZHX3 zinc fingers and homeoboxes 3
ZNF214 zinc finger protein 214
ZNF287 zinc finger protein 287
ZNF573 zinc finger protein 573
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ADGRE2 adhesion G protein-coupled receptor E2
ALOX12 arachidonate 12-lipoxygenase
ALPK1 alpha-kinase 1
ANXA10 annexin A10
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOC4 apolipoprotein C-IV
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMCX4 armadillo repeat containing, X-linked 4
ARSB arylsulfatase B
BFSP1 beaded filament structural protein 1, filensin
BMP15 bone morphogenetic protein 15
BTF3P11 basic transcription factor 3 pseudogene 11
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF105 chromosome 14 open reading frame 105
C1ORF21 chromosome 1 open reading frame 21
C5 complement component 5
C7ORF69 chromosome 7 open reading frame 69
CA9 carbonic anhydrase IX
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC94 coiled-coil domain containing 94
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD70 CD70 molecule
CDON cell adhesion associated, oncogene regulated
CINP cyclin-dependent kinase 2 interacting protein
CYBRD1 cytochrome b reductase 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DSPP dentin sialophosphoprotein
ERO1LB ERO1-like beta (S. cerevisiae)
FGF23 fibroblast growth factor 23
FLT4 fms-related tyrosine kinase 4
FRMPD1 FERM and PDZ domain containing 1
FRS3 fibroblast growth factor receptor substrate 3
GPC3 glypican 3
GPR3 G protein-coupled receptor 3
GRM4 glutamate receptor, metabotropic 4
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HHAT hedgehog acyltransferase
HIST1H1D histone cluster 1, H1d
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HSPA1L heat shock 70kDa protein 1-like
IFI44L interferon-induced protein 44-like
IL7 interleukin 7
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
LMCD1 LIM and cysteine-rich domains 1
LPAR4 lysophosphatidic acid receptor 4
LRRK1 leucine-rich repeat kinase 1
LY6D lymphocyte antigen 6 complex, locus D
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPD3 LY6/PLAUR domain containing 3
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MICALL2 MICAL-like 2
MMP3 matrix metallopeptidase 3
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAG18 NAG18 mRNA
NTSR1 neurotensin receptor 1 (high affinity)
NUP62CL nucleoporin 62kDa C-terminal like
ODF2 outer dense fiber of sperm tails 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSBP2 oxysterol binding protein 2
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDE8B phosphodiesterase 8B
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLAG1 pleiomorphic adenoma gene 1
PLXNB3 plexin B3
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POMT2 protein-O-mannosyltransferase 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRSS53 protease, serine, 53
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RGCC regulator of cell cycle
RIMBP2 RIMS binding protein 2
RNF126P1 ring finger protein 126 pseudogene 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SAYSD1 SAYSVFN motif domain containing 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SELENBP1 selenium binding protein 1
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT6 sirtuin 6
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TIGD6 tigger transposable element derived 6
TMEM212 transmembrane protein 212
TSNAXIP1 translin-associated factor X interacting protein 1
TTLL1 tubulin tyrosine ligase-like family member 1
WNT1 wingless-type MMTV integration site family, member 1
ZNF222 zinc finger protein 222
ZNF862 zinc finger protein 862