N-acetyl-L-aspartic acid-1329 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the N-acetyl-L-aspartic acid-1329 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADRBK1 adrenergic, beta, receptor kinase 1
ALPK1 alpha-kinase 1
AMDHD2 amidohydrolase domain containing 2
APLP2 amyloid beta (A4) precursor-like protein 2
ARFRP1 ADP-ribosylation factor related protein 1
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
C11ORF68 chromosome 11 open reading frame 68
CACTIN cactin, spliceosome C complex subunit
CD52 CD52 molecule
CDK13 cyclin-dependent kinase 13
CES3 carboxylesterase 3
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DMTF1 cyclin D binding myb-like transcription factor 1
EDC3 enhancer of mRNA decapping 3
EMILIN2 elastin microfibril interfacer 2
ENG endoglin
ERCC4 excision repair cross-complementation group 4
FAM3A family with sequence similarity 3, member A
FMO5 flavin containing monooxygenase 5
FUZ fuzzy planar cell polarity protein
GALE UDP-galactose-4-epimerase
GM2A GM2 ganglioside activator
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GTF2I general transcription factor IIi
HRH1 histamine receptor H1
IDI2-AS1 IDI2 antisense RNA 1
INO80D INO80 complex subunit D
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITGB1BP1 integrin beta 1 binding protein 1
KIAA0355 KIAA0355
KPNA4 karyopherin alpha 4 (importin alpha 3)
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LOC390998 ribosomal protein L10 pseudogene
LPAR1 lysophosphatidic acid receptor 1
LRP3 low density lipoprotein receptor-related protein 3
MAGEH1 melanoma antigen family H1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MID2 midline 2
MIIP migration and invasion inhibitory protein
MRC2 mannose receptor, C type 2
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NF1 neurofibromin 1
NUMB numb homolog (Drosophila)
NUP160 nucleoporin 160kDa
OSBPL2 oxysterol binding protein-like 2
PCGF2 polycomb group ring finger 2
PDCD2 programmed cell death 2
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
PLD2 phospholipase D2
PLK4 polo-like kinase 4
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTK2B protein tyrosine kinase 2 beta
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RANGAP1 Ran GTPase activating protein 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPL10 ribosomal protein L10
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RUNX1 runt-related transcription factor 1
SBF1 SET binding factor 1
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SLC12A9 solute carrier family 12, member 9
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SMC1A structural maintenance of chromosomes 1A
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SPATA2 spermatogenesis associated 2
SRR serine racemase
SRRT serrate, RNA effector molecule
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STAT1 signal transducer and activator of transcription 1, 91kDa
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SURF1 surfeit 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
TCP11L1 t-complex 11, testis-specific-like 1
TMOD3 tropomodulin 3 (ubiquitous)
TRAIP TRAF interacting protein
TSC22D3 TSC22 domain family, member 3
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE3A ubiquitin protein ligase E3A
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VAV2 vav 2 guanine nucleotide exchange factor
VEGFA vascular endothelial growth factor A
WFDC2 WAP four-disulfide core domain 2
ZBTB22 zinc finger and BTB domain containing 22
ZNF277 zinc finger protein 277
ZNF286A zinc finger protein 286A
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACPP acid phosphatase, prostate
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ACVR2B activin A receptor, type IIB
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADGRE2 adhesion G protein-coupled receptor E2
APOBR apolipoprotein B receptor
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARMCX5 armadillo repeat containing, X-linked 5
ASB6 ankyrin repeat and SOCS box containing 6
BCL2L2 BCL2-like 2
BCL7B B-cell CLL/lymphoma 7B
BLVRB biliverdin reductase B
BTBD18 BTB (POZ) domain containing 18
CARM1 coactivator-associated arginine methyltransferase 1
CD3D CD3d molecule, delta (CD3-TCR complex)
CECR1 cat eye syndrome chromosome region, candidate 1
CEP97 centrosomal protein 97kDa
CHMP1A charged multivesicular body protein 1A
CHST10 carbohydrate sulfotransferase 10
CRNKL1 crooked neck pre-mRNA splicing factor 1
CTSD cathepsin D
DEAF1 DEAF1 transcription factor
DGAT1 diacylglycerol O-acyltransferase 1
DUSP4 dual specificity phosphatase 4
ELP6 elongator acetyltransferase complex subunit 6
EPHB6 EPH receptor B6
ERCC2 excision repair cross-complementation group 2
ERCC5 excision repair cross-complementation group 5
EXOC2 exocyst complex component 2
FAM173A family with sequence similarity 173, member A
FAM184A family with sequence similarity 184, member A
FAM63A family with sequence similarity 63, member A
FBXL15 F-box and leucine-rich repeat protein 15
FOSL1 FOS-like antigen 1
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GEMIN8 gem (nuclear organelle) associated protein 8
GMEB1 glucocorticoid modulatory element binding protein 1
GPR63 G protein-coupled receptor 63
GTF2IRD1 GTF2I repeat domain containing 1
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIST3H2A histone cluster 3, H2a
INF2 inverted formin, FH2 and WH2 domain containing
KLHDC4 kelch domain containing 4
KPTN kaptin (actin binding protein)
LHFP lipoma HMGIC fusion partner
LIMD2 LIM domain containing 2
LINC00597 long intergenic non-protein coding RNA 597
LRRK1 leucine-rich repeat kinase 1
LY75 lymphocyte antigen 75
MANSC1 MANSC domain containing 1
MBTD1 mbt domain containing 1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MRPL34 mitochondrial ribosomal protein L34
MTRF1 mitochondrial translational release factor 1
NPFFR1 neuropeptide FF receptor 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PTDSS2 phosphatidylserine synthase 2
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
REEP4 receptor accessory protein 4
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
RHOBTB1 Rho-related BTB domain containing 1
RNF122 ring finger protein 122
RPAP1 RNA polymerase II associated protein 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RSRC1 arginine/serine-rich coiled-coil 1
SETMAR SET domain and mariner transposase fusion gene
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIDT1 SID1 transmembrane family, member 1
SIPA1 signal-induced proliferation-associated 1
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SNHG20 small nucleolar RNA host gene 20
SPINT1 serine peptidase inhibitor, Kunitz type 1
STK16 serine/threonine kinase 16
STX17 syntaxin 17
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTA T-cell leukemia translocation altered
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TKFC triokinase/FMN cyclase
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TTC4 tetratricopeptide repeat domain 4
WNT10B wingless-type MMTV integration site family, member 10B
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBED1 zinc finger, BED-type containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZDHHC18 zinc finger, DHHC-type containing 18
ZDHHC24 zinc finger, DHHC-type containing 24
ZNF551 zinc finger protein 551
ZNF629 zinc finger protein 629
ZNF721 zinc finger protein 721
ZNF813 zinc finger protein 813