Musculoskeletal Abnormalities Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D009139
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Genes

120 genes/proteins associated with the disease Musculoskeletal Abnormalities from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
SKI SKI proto-oncogene 2.88009
RARG retinoic acid receptor, gamma 2.88009
FOXC2 forkhead box C2 2.88009
TGFB2 transforming growth factor, beta 2 2.88009
TMCO1 transmembrane and coiled-coil domains 1 2.88009
HSPE1 heat shock 10kDa protein 1 1.51155
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.45273
RAD50 RAD50 homolog (S. cerevisiae) 1.4313
DDIT3 DNA-damage-inducible transcript 3 1.4313
CCND1 cyclin D1 1.40092
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.35647
FOS FBJ murine osteosarcoma viral oncogene homolog 1.34983
HSPB1 heat shock 27kDa protein 1 1.32399
TXNRD1 thioredoxin reductase 1 1.30087
VEGFA vascular endothelial growth factor A 1.29011
IL6 interleukin 6 1.29011
BAX BCL2-associated X protein 1.27782
MCM5 minichromosome maintenance complex component 5 1.24623
KLF4 Kruppel-like factor 4 (gut) 1.22758
BTG1 B-cell translocation gene 1, anti-proliferative 1.22758
ATF2 activating transcription factor 2 1.22339
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.22242
HSPA8 heat shock 70kDa protein 8 1.22177
NRP1 neuropilin 1 1.21759
RPA2 replication protein A2, 32kDa 1.21076
CCNC cyclin C 1.20394
PBX1 pre-B-cell leukemia homeobox 1 1.20328
EGR1 early growth response 1 1.20262
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.18093
HSPH1 heat shock 105kDa/110kDa protein 1 1.17761
GLUL glutamate-ammonia ligase 1.17431
CAT catalase 1.17134
RBBP4 retinoblastoma binding protein 4 1.16967
JUN jun proto-oncogene 1.16733
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.166
RRM2 ribonucleotide reductase M2 1.15357
CCND3 cyclin D3 1.15055
S1PR1 sphingosine-1-phosphate receptor 1 1.1461
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.13449
MAPT microtubule-associated protein tau 1.12426
ATF4 activating transcription factor 4 1.12288
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.12185
ACTB actin, beta 1.12151
CXCL2 chemokine (C-X-C motif) ligand 2 1.11741
EPB41 erythrocyte membrane protein band 4.1 1.11741
BCL2 B-cell CLL/lymphoma 2 1.11707
EIF5 eukaryotic translation initiation factor 5 1.11431
GLRX glutaredoxin (thioltransferase) 1.11186
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 1.11186
CTSD cathepsin D 1.11081
CXCL3 chemokine (C-X-C motif) ligand 3 1.10699
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.10699
STIP1 stress-induced phosphoprotein 1 1.10527
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.10353
PRKCD protein kinase C, delta 1.10317
TACR1 tachykinin receptor 1 1.10246
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.10033
RAN RAN, member RAS oncogene family 1.09998
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.09786
FYN FYN proto-oncogene, Src family tyrosine kinase 1.09751
KLF5 Kruppel-like factor 5 (intestinal) 1.09751
EIF4E eukaryotic translation initiation factor 4E 1.09541
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.0869
GATA3 GATA binding protein 3 1.08655
PHGDH phosphoglycerate dehydrogenase 1.08196
GSTO1 glutathione S-transferase omega 1 1.08196
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 1.08019
ALB albumin 1.07947
CDK16 cyclin-dependent kinase 16 1.07947
MSH2 mutS homolog 2 1.07768
PTP4A1 protein tyrosine phosphatase type IVA, member 1 1.07768
MAPK3 mitogen-activated protein kinase 3 1.07768
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.07768
HSPA4 heat shock 70kDa protein 4 1.07553
PRPF4B pre-mRNA processing factor 4B 1.07482
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.07163
PPARG peroxisome proliferator-activated receptor gamma 1.07093
PCNA proliferating cell nuclear antigen 1.07022
MAPK1 mitogen-activated protein kinase 1 1.06952
CDKN2A cyclin-dependent kinase inhibitor 2A 1.06808
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 1.06734
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.06588
CDKN3 cyclin-dependent kinase inhibitor 3 1.06552
UNG uracil-DNA glycosylase 1.06515
GDF15 growth differentiation factor 15 1.06116
H2AFX H2A histone family, member X 1.06116
EPAS1 endothelial PAS domain protein 1 1.05936
ZNF394 zinc finger protein 394 1.05573
GJA1 gap junction protein, alpha 1, 43kDa 1.05573
TP53 tumor protein p53 1.05498
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 1.052
NAMPT nicotinamide phosphoribosyltransferase 1.04574
IGF1 insulin-like growth factor 1 (somatomedin C) 1.04427
NOS2 nitric oxide synthase 2, inducible 1.04201
EEF2 eukaryotic translation elongation factor 2 1.04051
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.04014
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.04014
INSR insulin receptor 1.03827
TSC22D1 TSC22 domain family, member 1 1.03641
ILF3 interleukin enhancer binding factor 3, 90kDa 1.03567
CDK4 cyclin-dependent kinase 4 1.03235
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 1.03159
TH tyrosine hydroxylase 1.03122
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.03084
HSPA1A heat shock 70kDa protein 1A 1.03009
SOD2 superoxide dismutase 2, mitochondrial 1.02971
HIST4H4 histone cluster 4, H4 1.02896
NISCH nischarin 1.02858
UBE2B ubiquitin-conjugating enzyme E2B 1.02821
BMP4 bone morphogenetic protein 4 1.02746
EGFR epidermal growth factor receptor 1.02522
CXCL10 chemokine (C-X-C motif) ligand 10 1.02485
PLA2G16 phospholipase A2, group XVI 1.02003
PRNP prion protein 1.0189
PDGFA platelet-derived growth factor alpha polypeptide 1.01852
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.01701
SP3 Sp3 transcription factor 1.01625
JUND jun D proto-oncogene 1.01512
CCNA2 cyclin A2 1.01324
MEF2A myocyte enhancer factor 2A 1.01286