Muscular Atrophy Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D009133
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Genes

289 genes/proteins associated with the disease Muscular Atrophy from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
AMPD1 adenosine monophosphate deaminase 1 2.88009
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.88009
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 2.88009
FBXO32 F-box protein 32 2.88009
TTPA tocopherol (alpha) transfer protein 2.88009
GH1 growth hormone 1 2.88009
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.88009
IGF1 insulin-like growth factor 1 (somatomedin C) 2.88009
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.88009
GSK3B glycogen synthase kinase 3 beta 2.88009
WWTR1 WW domain containing transcription regulator 1 2.88009
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 2.88009
IL1B interleukin 1, beta 2.04358
TNF tumor necrosis factor 1.95585
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.89137
IL6 interleukin 6 1.84835
CAT catalase 1.83771
ICAM1 intercellular adhesion molecule 1 1.83717
CXCL8 chemokine (C-X-C motif) ligand 8 1.82814
VEGFA vascular endothelial growth factor A 1.7625
BAX BCL2-associated X protein 1.76151
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.7546
TGFB1 transforming growth factor, beta 1 1.71769
FAS Fas cell surface death receptor 1.71255
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.71029
BCL2 B-cell CLL/lymphoma 2 1.70968
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.70014
CCL2 chemokine (C-C motif) ligand 2 1.69167
GSR glutathione reductase 1.65599
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.6538
IL1A interleukin 1, alpha 1.62268
BTG2 BTG family, member 2 1.58912
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.58467
VCAM1 vascular cell adhesion molecule 1 1.56239
NFE2L1 nuclear factor, erythroid 2-like 1 1.55133
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.54766
ATF3 activating transcription factor 3 1.54354
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.53209
EDN1 endothelin 1 1.52011
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.51607
CFLAR CASP8 and FADD-like apoptosis regulator 1.51481
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.50928
IL4 interleukin 4 1.48813
IFNG interferon, gamma 1.47864
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.47582
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.4633
GFAP glial fibrillary acidic protein 1.44817
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.43946
BCL2L1 BCL2-like 1 1.43782
JUN jun proto-oncogene 1.43076
PER1 period circadian clock 1 1.42913
IL10 interleukin 10 1.42859
IL2 interleukin 2 1.42723
SOD2 superoxide dismutase 2, mitochondrial 1.4202
GPX1 glutathione peroxidase 1 1.41938
POMC proopiomelanocortin 1.41613
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.41532
DDIT3 DNA-damage-inducible transcript 3 1.40623
ACACA acetyl-CoA carboxylase alpha 1.40316
AK3 adenylate kinase 3 1.40064
CD4 CD4 molecule 1.40064
TAT tyrosine aminotransferase 1.40036
EGFR epidermal growth factor receptor 1.39058
EDNRB endothelin receptor type B 1.38298
HMOX1 heme oxygenase 1 1.38298
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.3827
GADD45A growth arrest and DNA-damage-inducible, alpha 1.3793
DUSP1 dual specificity phosphatase 1 1.37418
STAR steroidogenic acute regulatory protein 1.37418
ACO2 aconitase 2, mitochondrial 1.37132
SGK1 serum/glucocorticoid regulated kinase 1 1.37075
NOS2 nitric oxide synthase 2, inducible 1.36791
FASN fatty acid synthase 1.36533
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.35906
CAV1 caveolin 1, caveolae protein, 22kDa 1.35213
GSN gelsolin 1.35184
DDIT4 DNA-damage-inducible transcript 4 1.34752
CCNA2 cyclin A2 1.34372
PRL prolactin 1.34256
MAPK1 mitogen-activated protein kinase 1 1.33966
EGR1 early growth response 1 1.33081
CCND1 cyclin D1 1.33052
GSTP1 glutathione S-transferase pi 1 1.32846
FKBP5 FK506 binding protein 5 1.32251
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 1.31985
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.31357
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.31089
CREBBP CREB binding protein 1.30543
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.30329
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.29936
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.2975
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.29317
MMP9 matrix metallopeptidase 9 1.28919
MYOD1 myogenic differentiation 1 1.28734
NOS3 nitric oxide synthase 3 (endothelial cell) 1.28518
CD36 CD36 molecule (thrombospondin receptor) 1.28487
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.28333
IL5 interleukin 5 1.2821
PLAT plasminogen activator, tissue 1.2821
G6PD glucose-6-phosphate dehydrogenase 1.28058
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.27997
UBC ubiquitin C 1.27595
CLU clusterin 1.27255
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.27009
FOS FBJ murine osteosarcoma viral oncogene homolog 1.26825
HRAS Harvey rat sarcoma viral oncogene homolog 1.26732
CRH corticotropin releasing hormone 1.26638
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.26483
ANGPTL4 angiopoietin-like 4 1.26452
MAPK3 mitogen-activated protein kinase 3 1.26205
ODC1 ornithine decarboxylase 1 1.25588
F3 coagulation factor III (thromboplastin, tissue factor) 1.23837
DCN decorin 1.23584
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.23584
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.2336
PLD1 phospholipase D1, phosphatidylcholine-specific 1.23328
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 1.23074
LEPR leptin receptor 1.23011
MGMT O-6-methylguanine-DNA methyltransferase 1.23011
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.22436
TF transferrin 1.22177
CD44 CD44 molecule (Indian blood group) 1.22016
IGF1R insulin-like growth factor 1 receptor 1.21855
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.21695
SLCO2A1 solute carrier organic anion transporter family, member 2A1 1.21534
HNF4A hepatocyte nuclear factor 4, alpha 1.2137
BHLHE40 basic helix-loop-helix family, member e40 1.21141
FOXO1 forkhead box O1 1.20913
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.20816
TP53 tumor protein p53 1.19737
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.19672
F2 coagulation factor II (thrombin) 1.19672
ZFP36 ZFP36 ring finger protein 1.19312
TSC22D1 TSC22 domain family, member 1 1.18882
PPARA peroxisome proliferator-activated receptor alpha 1.18685
IGFBP3 insulin-like growth factor binding protein 3 1.18652
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.18226
ALB albumin 1.18093
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.17596
SFTPB surfactant protein B 1.17497
MMP2 matrix metallopeptidase 2 1.17235
ARNTL aryl hydrocarbon receptor nuclear translocator-like 1.17168
GADD45G growth arrest and DNA-damage-inducible, gamma 1.16967
TNNI3 troponin I type 3 (cardiac) 1.165
NR2F2 nuclear receptor subfamily 2, group F, member 2 1.165
SIVA1 SIVA1, apoptosis-inducing factor 1.16335
BIRC5 baculoviral IAP repeat containing 5 1.15763
CALR calreticulin 1.15593
MAPK8 mitogen-activated protein kinase 8 1.15593
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.1556
SPTAN1 spectrin, alpha, non-erythrocytic 1 1.1556
IL18 interleukin 18 1.15425
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 1.15223
TLR4 toll-like receptor 4 1.15055
TIMP3 TIMP metallopeptidase inhibitor 3 1.14816
EGR3 early growth response 3 1.1461
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.1461
SDC2 syndecan 2 1.1461
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.14575
EPO erythropoietin 1.14438
THBS1 thrombospondin 1 1.14234
FASLG Fas ligand (TNF superfamily, member 6) 1.14234
ADRB1 adrenoceptor beta 1 1.1403
POU5F1 POU class 5 homeobox 1 1.13997
SCG2 secretogranin II 1.13997
MCL1 myeloid cell leukemia 1 1.13862
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 1.13689
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.13484
GADD45B growth arrest and DNA-damage-inducible, beta 1.13313
CCNB1 cyclin B1 1.13245
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.13143
COL1A1 collagen, type I, alpha 1 1.13075
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.12973
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.1294
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.12771
IRS1 insulin receptor substrate 1 1.12599
RRM2 ribonucleotide reductase M2 1.12599
MYOG myogenin (myogenic factor 4) 1.12495
CDK4 cyclin-dependent kinase 4 1.1198
TH tyrosine hydroxylase 1.11877
GSTM1 glutathione S-transferase mu 1 1.11707
PARP1 poly (ADP-ribose) polymerase 1 1.11571
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.11571
ASS1 argininosuccinate synthase 1 1.11466
FAM107A family with sequence similarity 107, member A 1.1136
FADS1 fatty acid desaturase 1 1.11151
LHB luteinizing hormone beta polypeptide 1.11151
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.11011
PCNA proliferating cell nuclear antigen 1.10977
GCLC glutamate-cysteine ligase, catalytic subunit 1.10734
CCNE1 cyclin E1 1.10665
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 1.10424
PLCG1 phospholipase C, gamma 1 1.10388
MMP13 matrix metallopeptidase 13 1.10211
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.10211
CDC25A cell division cycle 25A 1.10104
CXCR4 chemokine (C-X-C motif) receptor 4 1.10033
TRPV2 transient receptor potential cation channel, subfamily V, member 2 1.09927
CCND2 cyclin D2 1.09857
IGFBP1 insulin-like growth factor binding protein 1 1.09366
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.09297
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.0919
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.09047
GCLM glutamate-cysteine ligase, modifier subunit 1.09047
ATM ATM serine/threonine kinase 1.08726
CDK2 cyclin-dependent kinase 2 1.08619
RNASEH2A ribonuclease H2, subunit A 1.08584
SCARB1 scavenger receptor class B, member 1 1.08407
JAK1 Janus kinase 1 1.08337
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.08161
GBP1 guanylate binding protein 1, interferon-inducible 1.08161
MMD monocyte to macrophage differentiation-associated 1.08126
ACE angiotensin I converting enzyme 1.07947
FABP4 fatty acid binding protein 4, adipocyte 1.07947
MMP3 matrix metallopeptidase 3 1.07768
CCS copper chaperone for superoxide dismutase 1.07696
PRIM2 primase, DNA, polypeptide 2 (58kDa) 1.0766
TPI1 triosephosphate isomerase 1 1.07625
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.07163
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.07163
BDNF brain-derived neurotrophic factor 1.06987
GCK glucokinase (hexokinase 4) 1.06917
KLF9 Kruppel-like factor 9 1.06917
PTPRK protein tyrosine phosphatase, receptor type, K 1.06881
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1.06881
PPIB peptidylprolyl isomerase B (cyclophilin B) 1.06844
ENC1 ectodermal-neural cortex 1 (with BTB domain) 1.06698
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.06661
POU2F1 POU class 2 homeobox 1 1.06479
GSK3A glycogen synthase kinase 3 alpha 1.06442
INS insulin 1.06442
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.06225
NQO1 NAD(P)H dehydrogenase, quinone 1 1.06116
CDK1 cyclin-dependent kinase 1 1.06008
ELOVL6 ELOVL fatty acid elongase 6 1.05972
KLF4 Kruppel-like factor 4 (gut) 1.05972
SERINC3 serine incorporator 3 1.05648
TREX1 three prime repair exonuclease 1 1.05648
IFT81 intraflagellar transport 81 1.05386
MGP matrix Gla protein 1.05312
SRGN serglycin 1.05237
AR androgen receptor 1.052
NR1H3 nuclear receptor subfamily 1, group H, member 3 1.05089
NOX4 NADPH oxidase 4 1.05089
NBN nibrin 1.04868
UBE2C ubiquitin-conjugating enzyme E2C 1.04868
RAD51C RAD51 paralog C 1.04868
ACHE acetylcholinesterase (Yt blood group) 1.04794
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.04647
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.04647
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.04501
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.04501
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 1.04465
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.04465
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.04427
LEP leptin 1.04352
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.04201
PDLIM7 PDZ and LIM domain 7 (enigma) 1.04088
INSR insulin receptor 1.04014
PRKCA protein kinase C, alpha 1.03789
CYB5A cytochrome b5 type A (microsomal) 1.03752
TIMP1 TIMP metallopeptidase inhibitor 1 1.03752
TPD52L1 tumor protein D52-like 1 1.03715
RAB31 RAB31, member RAS oncogene family 1.03715
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 1.03715
CLCN4 chloride channel, voltage-sensitive 4 1.03567
TAGLN transgelin 1.03345
PDIA3 protein disulfide isomerase family A, member 3 1.03122
TUBA4A tubulin, alpha 4a 1.03009
CTSL cathepsin L 1.02933
HPS1 Hermansky-Pudlak syndrome 1 1.02858
SOD3 superoxide dismutase 3, extracellular 1.02746
BMP4 bone morphogenetic protein 4 1.02708
MAP1B microtubule-associated protein 1B 1.02671
ACKR3 atypical chemokine receptor 3 1.02634
LAMB3 laminin, beta 3 1.02596
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 1.02559
FOXO3 forkhead box O3 1.02522
MMP1 matrix metallopeptidase 1 1.02447
MYF5 myogenic factor 5 1.02373
EGR2 early growth response 2 1.02114
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.0189
G6PC glucose-6-phosphatase, catalytic subunit 1.01701
BAD BCL2-associated agonist of cell death 1.01625
ITGB5 integrin, beta 5 1.01549
APOE apolipoprotein E 1.01361
MCAM melanoma cell adhesion molecule 1.01212
GJA1 gap junction protein, alpha 1, 43kDa 1.01137
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.01137