Muscle Rigidity Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Continuous involuntary sustained muscle contraction. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from muscle spasticity. (Human Phenotype Ontology, HP_0002063)
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Genes

9 genes associated with the Muscle Rigidity phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
APOE apolipoprotein E
BDNF brain-derived neurotrophic factor
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
LRRK2 leucine-rich repeat kinase 2
PARK2 parkin RBR E3 ubiquitin protein ligase
PRNP prion protein