Multiple System Atrophy Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description OMIM mapping confirmed by DO. [LS]. (Human Disease Ontology, DOID_4752)
Similar Terms
Downloads & Tools

Genes

34 genes associated with the Multiple System Atrophy phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
BDNF brain-derived neurotrophic factor
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
COMT catechol-O-methyltransferase
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
CST3 cystatin C
CXCL8 chemokine (C-X-C motif) ligand 8
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ETV6 ets variant 6
FMR1 fragile X mental retardation 1
FRAXA fragile site, folic acid type, rare, fra(X)(q27.3) A (macroorchidism, mental retardation)
GBA glucosidase, beta, acid
ICAM1 intercellular adhesion molecule 1
IL10 interleukin 10
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL6 interleukin 6
LRRK2 leucine-rich repeat kinase 2
MCPH1 microcephalin 1
MSX1 msh homeobox 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PINK1 PTEN induced putative kinase 1
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C
PRNP prion protein
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SQSTM1 sequestosome 1
TBP TATA box binding protein
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)