Multiple Sclerosis, Chronic Progressive Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

40 genes associated with the Multiple Sclerosis, Chronic Progressive phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
APOE apolipoprotein E
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CNR1 cannabinoid receptor 1 (brain)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL10 chemokine (C-X-C motif) ligand 10
DCTN1 dynactin 1
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRN granulin
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
HNMT histamine N-methyltransferase
IL10 interleukin 10
IL18R1 interleukin 18 receptor 1
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL4R interleukin 4 receptor
IL7R interleukin 7 receptor
KIF1B kinesin family member 1B
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MEFV Mediterranean fever
NQO1 NAD(P)H dehydrogenase, quinone 1
PLAU plasminogen activator, urokinase
PRNP prion protein
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SPP1 secreted phosphoprotein 1
SYN3 synapsin III
TBATA thymus, brain and testes associated
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor