Mouth Neoplasms Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

292 genes associated with the Mouth Neoplasms phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACE angiotensin I converting enzyme
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH6 alcohol dehydrogenase 6 (class V)
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANKK1 ankyrin repeat and kinase domain containing 1
APC adenomatous polyposis coli
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ATM ATM serine/threonine kinase
AURKA aurora kinase A
AXIN1 axin 1
AXIN2 axin 2
BARD1 BRCA1 associated RING domain 1
BAX BCL2-associated X protein
BCL6 B-cell CLL/lymphoma 6
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRMS1 breast cancer metastasis suppressor 1
CA9 carbonic anhydrase IX
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASP1 caspase 1, apoptosis-related cysteine peptidase
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCND2 cyclin D2
CCNH cyclin H
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD28 CD28 molecule
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK4 cyclin-dependent kinase 4
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHEK2 checkpoint kinase 2
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CNTNAP2 contactin associated protein-like 2
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COMT catechol-O-methyltransferase
CPB2 carboxypeptidase B2 (plasma)
CRYAB crystallin, alpha B
CST3 cystatin C
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSB cathepsin B
CTTN cortactin
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DCC DCC netrin 1 receptor
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DEC1 deleted in esophageal cancer 1
DGCR8 DGCR8 microprocessor complex subunit
DICER1 dicer 1, ribonuclease type III
DLEC1 deleted in lung and esophageal cancer 1
DRD2 dopamine receptor D2
EGFR epidermal growth factor receptor
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
ERCC6 excision repair cross-complementation group 6
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EXO1 exonuclease 1
F12 coagulation factor XII (Hageman factor)
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FAM212B family with sequence similarity 212, member B
FANCG Fanconi anemia, complementation group G
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FGF3 fibroblast growth factor 3
FGFR4 fibroblast growth factor receptor 4
FHIT fragile histidine triad
FLNC filamin C, gamma
FUT2 fucosyltransferase 2 (secretor status included)
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13
GAS1 growth arrest-specific 1
GEMIN4 gem (nuclear organelle) associated protein 4
GJB5 gap junction protein, beta 5, 31.1kDa
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPX1 glutathione peroxidase 1
GRIK2 glutamate receptor, ionotropic, kainate 2
GSK3B glycogen synthase kinase 3 beta
GSTA1 glutathione S-transferase alpha 1
GSTA2 glutathione S-transferase alpha 2
GSTM1 glutathione S-transferase mu 1
GSTM3 glutathione S-transferase mu 3 (brain)
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-C major histocompatibility complex, class I, C
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
HRAS Harvey rat sarcoma viral oncogene homolog
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2R insulin-like growth factor 2 receptor
IL10 interleukin 10
IL12B interleukin 12B
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL2 interleukin 2
IL23R interleukin 23 receptor
IL4 interleukin 4
IL6 interleukin 6
IRAK3 interleukin-1 receptor-associated kinase 3
IRF6 interferon regulatory factor 6
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB5 integrin, beta 5
KDM4C lysine (K)-specific demethylase 4C
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LEP leptin
LEPR leptin receptor
LIG3 ligase III, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
LOX lysyl oxidase
LTA lymphotoxin alpha
LTBP1 latent transforming growth factor beta binding protein 1
LZTS1 leucine zipper, putative tumor suppressor 1
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAPK1 mitogen-activated protein kinase 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MGMT O-6-methylguanine-DNA methyltransferase
MIR100 microRNA 100
MIR124-1 microRNA 124-1
MIR146A microRNA 146a
MIR149 microRNA 149
MIR196A2 microRNA 196a-2
MIR219A1 microRNA 219a-1
MIR26A1 microRNA 26a-1
MIR30A microRNA 30a
MIR30C1 microRNA 30c-1
MIR34B microRNA 34b
MIR373 microRNA 373
MIR423 microRNA 423
MIR492 microRNA 492
MIR499A microRNA 499a
MIR604 microRNA 604
MIR608 microRNA 608
MLH1 mutL homolog 1
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH3 mutS homolog 3
MSH6 mutS homolog 6
MT-TL2 tRNA
MT1A metallothionein 1A
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUTYH mutY homolog
MVP major vault protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NBL1 neuroblastoma 1, DAN family BMP antagonist
NBN nibrin
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOTCH1 notch 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
OGG1 8-oxoguanine DNA glycosylase
PCNA proliferating cell nuclear antigen
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
POLB polymerase (DNA directed), beta
PON1 paraoxonase 1
POPDC3 popeye domain containing 3
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPRJ protein tyrosine phosphatase, receptor type, J
RAG1 recombination activating gene 1
RAN RAN, member RAS oncogene family
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RB1 retinoblastoma 1
RECK reversion-inducing-cysteine-rich protein with kazal motifs
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RNASE3 ribonuclease, RNase A family, 3
RNF139 ring finger protein 139
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIM2 single-minded family bHLH transcription factor 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SOD2 superoxide dismutase 2, mitochondrial
SPP1 secreted phosphoprotein 1
STAT5B signal transducer and activator of transcription 5B
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYK spleen tyrosine kinase
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMP2 TIMP metallopeptidase inhibitor 2
TMPRSS11A transmembrane protease, serine 11A
TNF tumor necrosis factor
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TP53 tumor protein p53
TP73 tumor protein p73
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TUSC3 tumor suppressor candidate 3
TYMS thymidylate synthetase
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
WNT11 wingless-type MMTV integration site family, member 11
WNT3 wingless-type MMTV integration site family, member 3
WNT3A wingless-type MMTV integration site family, member 3A
WNT5A wingless-type MMTV integration site family, member 5A
WNT8A wingless-type MMTV integration site family, member 8A
WNT9B wingless-type MMTV integration site family, member 9B
WRAP53 WD repeat containing, antisense to TP53
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6