Mouth Neoplasms Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D009062
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Genes

310 genes/proteins associated with the disease Mouth Neoplasms from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
TP53 tumor protein p53 2.88009
TSC1 tuberous sclerosis 1 2.88009
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.88009
ANXA1 annexin A1 2.88009
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 2.88009
HOXD10 homeobox D10 2.88009
FGA fibrinogen alpha chain 2.88009
ANXA5 annexin A5 2.88009
SIRT3 sirtuin 3 2.88009
PPIA peptidylprolyl isomerase A (cyclophilin A) 2.88009
HRAS Harvey rat sarcoma viral oncogene homolog 2.88009
HOXD11 homeobox D11 2.88009
ICAM1 intercellular adhesion molecule 1 2.88009
SOD2 superoxide dismutase 2, mitochondrial 2.88009
IL18 interleukin 18 2.88009
KRT6B keratin 6B, type II 2.88009
DSPP dentin sialophosphoprotein 2.88009
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.88009
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 2.88009
TSC2 tuberous sclerosis 2 2.88009
MRPL13 mitochondrial ribosomal protein L13 2.88009
KRAS Kirsten rat sarcoma viral oncogene homolog 2.88009
PGAM1 phosphoglycerate mutase 1 (brain) 2.88009
HSPA8 heat shock 70kDa protein 8 2.88009
MT1A metallothionein 1A 2.88009
ATP7B ATPase, Cu++ transporting, beta polypeptide 2.88009
UMPS uridine monophosphate synthetase 2.88009
SFN stratifin 2.88009
LGALS7 lectin, galactoside-binding, soluble, 7 2.88009
ENO1 enolase 1, (alpha) 2.88009
HSPB1 heat shock 27kDa protein 1 2.88009
PRTFDC1 phosphoribosyl transferase domain containing 1 2.88009
CRYAB crystallin, alpha B 2.88009
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 2.88009
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.88009
VDAC2 voltage-dependent anion channel 2 2.88009
TPI1 triosephosphate isomerase 1 2.88009
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 2.88009
ANXA2 annexin A2 2.88009
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 2.88009
HOXA5 homeobox A5 2.88009
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 2.88009
PARP1 poly (ADP-ribose) polymerase 1 1.73719
BCL2 B-cell CLL/lymphoma 2 1.73211
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.71932
BCL2L1 BCL2-like 1 1.71769
CCNB1 cyclin B1 1.70035
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.69211
H2AFX H2A histone family, member X 1.69125
CCND1 cyclin D1 1.67825
CDK1 cyclin-dependent kinase 1 1.67569
GCLC glutamate-cysteine ligase, catalytic subunit 1.67333
MMP9 matrix metallopeptidase 9 1.66706
IL6 interleukin 6 1.66641
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.65068
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.63317
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.63094
JUN jun proto-oncogene 1.61037
HMOX1 heme oxygenase 1 1.60781
CXCL8 chemokine (C-X-C motif) ligand 8 1.59826
IGF1 insulin-like growth factor 1 (somatomedin C) 1.55946
BID BH3 interacting domain death agonist 1.54402
BBC3 BCL2 binding component 3 1.5382
EGFR epidermal growth factor receptor 1.53456
VEGFA vascular endothelial growth factor A 1.53332
BIRC2 baculoviral IAP repeat containing 2 1.52616
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.51936
MAPK8 mitogen-activated protein kinase 8 1.51506
TNF tumor necrosis factor 1.5123
IL1B interleukin 1, beta 1.50398
NQO1 NAD(P)H dehydrogenase, quinone 1 1.49558
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.49457
FGF2 fibroblast growth factor 2 (basic) 1.49148
F3 coagulation factor III (thromboplastin, tissue factor) 1.49148
SP1 Sp1 transcription factor 1.48222
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.47864
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.47348
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.47219
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.46251
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.4522
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.44626
MMP2 matrix metallopeptidase 2 1.44436
NOS2 nitric oxide synthase 2, inducible 1.443
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 1.44029
COL1A1 collagen, type I, alpha 1 1.4351
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.42238
ATF3 activating transcription factor 3 1.42238
MAPK14 mitogen-activated protein kinase 14 1.42129
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.41938
GSTT1 glutathione S-transferase theta 1 1.41884
MAP2K1 mitogen-activated protein kinase kinase 1 1.41285
PCNA proliferating cell nuclear antigen 1.41202
MKI67 marker of proliferation Ki-67 1.41119
CDKN2A cyclin-dependent kinase inhibitor 2A 1.40815
CTGF connective tissue growth factor 1.40677
MMP1 matrix metallopeptidase 1 1.40677
IFNG interferon, gamma 1.40429
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.40064
BAD BCL2-associated agonist of cell death 1.39757
STAT1 signal transducer and activator of transcription 1, 91kDa 1.3917
SOD1 superoxide dismutase 1, soluble 1.38641
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.38213
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.38043
GSTP1 glutathione S-transferase pi 1 1.37761
ERBB2 erb-b2 receptor tyrosine kinase 2 1.37676
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.37619
MGMT O-6-methylguanine-DNA methyltransferase 1.37132
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.36763
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.36648
BIRC5 baculoviral IAP repeat containing 5 1.36648
BAX BCL2-associated X protein 1.36304
MMP3 matrix metallopeptidase 3 1.3556
NFE2L2 nuclear factor, erythroid 2-like 2 1.35271
GSR glutathione reductase 1.33523
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.33346
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.32786
MAPK3 mitogen-activated protein kinase 3 1.32577
IGFBP3 insulin-like growth factor binding protein 3 1.32369
PPARG peroxisome proliferator-activated receptor gamma 1.32015
IL12B interleukin 12B 1.31927
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.31927
LDLR low density lipoprotein receptor 1.31566
RAD51 RAD51 recombinase 1.31506
MAPK1 mitogen-activated protein kinase 1 1.31446
TGFB1 transforming growth factor, beta 1 1.31297
GPX2 glutathione peroxidase 2 1.31089
THBS1 thrombospondin 1 1.30881
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.30758
BDNF brain-derived neurotrophic factor 1.30451
NGF nerve growth factor (beta polypeptide) 1.30177
KEAP1 kelch-like ECH-associated protein 1 1.29626
CCL5 chemokine (C-C motif) ligand 5 1.29256
CFLAR CASP8 and FADD-like apoptosis regulator 1.29225
CAT catalase 1.29194
FOS FBJ murine osteosarcoma viral oncogene homolog 1.29103
CYR61 cysteine-rich, angiogenic inducer, 61 1.29011
TOP2A topoisomerase (DNA) II alpha 170kDa 1.28796
CCND3 cyclin D3 1.2861
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.28027
GSK3B glycogen synthase kinase 3 beta 1.27875
FASLG Fas ligand (TNF superfamily, member 6) 1.27471
CXCL2 chemokine (C-X-C motif) ligand 2 1.27193
DDIT3 DNA-damage-inducible transcript 3 1.27039
TIMP1 TIMP metallopeptidase inhibitor 1 1.26856
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.26421
S100A4 S100 calcium binding protein A4 1.26113
IL7 interleukin 7 1.25929
TUBB tubulin, beta class I 1.25929
IL12A interleukin 12A 1.25776
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.25619
KLF4 Kruppel-like factor 4 (gut) 1.25619
TRAF1 TNF receptor-associated factor 1 1.25557
GADD45A growth arrest and DNA-damage-inducible, alpha 1.25214
CD44 CD44 molecule (Indian blood group) 1.24181
DPYD dihydropyrimidine dehydrogenase 1.24118
GGT1 gamma-glutamyltransferase 1 1.23899
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.23648
SQSTM1 sequestosome 1 1.23328
MAPK10 mitogen-activated protein kinase 10 1.22979
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 1.22979
COL1A2 collagen, type I, alpha 2 1.22979
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.22821
CCNA2 cyclin A2 1.22501
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.22274
GSTM1 glutathione S-transferase mu 1 1.21695
WISP1 WNT1 inducible signaling pathway protein 1 1.21599
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.21534
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.21468
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.21304
CDK2 cyclin-dependent kinase 2 1.21206
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.20654
MT2A metallothionein 2A 1.20493
BIRC3 baculoviral IAP repeat containing 3 1.20031
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.19999
LBP lipopolysaccharide binding protein 1.19933
WT1 Wilms tumor 1 1.19933
PRC1 protein regulator of cytokinesis 1 1.19607
IL2 interleukin 2 1.18948
CDC25C cell division cycle 25C 1.18915
PRKDC protein kinase, DNA-activated, catalytic polypeptide 1.18685
HSPB8 heat shock 22kDa protein 8 1.18391
CDC20 cell division cycle 20 1.18293
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.18159
PTK2 protein tyrosine kinase 2 1.18093
CYBA cytochrome b-245, alpha polypeptide 1.17893
TERT telomerase reverse transcriptase 1.17268
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.17101
GDF15 growth differentiation factor 15 1.17
FANCG Fanconi anemia, complementation group G 1.16967
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.169
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.166
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.166
TGFBR3 transforming growth factor, beta receptor III 1.165
RRM2 ribonucleotide reductase M2 1.16302
DDIT4L DNA-damage-inducible transcript 4-like 1.16035
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 1.15865
SOX18 SRY (sex determining region Y)-box 18 1.15593
MCL1 myeloid cell leukemia 1 1.15256
NOS3 nitric oxide synthase 3 (endothelial cell) 1.14954
CSF1 colony stimulating factor 1 (macrophage) 1.14919
IL4 interleukin 4 1.14781
BAK1 BCL2-antagonist/killer 1 1.14747
AGR2 anterior gradient 2 1.14678
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.14268
APLN apelin 1.14268
CD79A CD79a molecule, immunoglobulin-associated alpha 1.14234
CXCR4 chemokine (C-X-C motif) receptor 4 1.13449
BGN biglycan 1.13415
CDK4 cyclin-dependent kinase 4 1.13211
E2F1 E2F transcription factor 1 1.13109
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.1294
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.12634
DIABLO diablo, IAP-binding mitochondrial protein 1.12564
CXCL10 chemokine (C-X-C motif) ligand 10 1.12288
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.12219
HDAC1 histone deacetylase 1 1.12048
VCAM1 vascular cell adhesion molecule 1 1.12014
SAT1 spermidine/spermine N1-acetyltransferase 1 1.1198
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 1.11945
C3 complement component 3 1.11877
BECN1 beclin 1, autophagy related 1.11809
CCNE1 cyclin E1 1.11775
ERCC1 excision repair cross-complementation group 1 1.11571
RB1 retinoblastoma 1 1.11536
TIMP2 TIMP metallopeptidase inhibitor 2 1.11186
MAPK9 mitogen-activated protein kinase 9 1.11151
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.10872
CYCS cytochrome c, somatic 1.10631
UBE2C ubiquitin-conjugating enzyme E2C 1.10596
SNAI2 snail family zinc finger 2 1.10282
CXCL12 chemokine (C-X-C motif) ligand 12 1.10175
GCLM glutamate-cysteine ligase, modifier subunit 1.09998
PCF11 PCF11 cleavage and polyadenylation factor subunit 1.09857
PRKCD protein kinase C, delta 1.09857
CP ceruloplasmin (ferroxidase) 1.09857
EPRS glutamyl-prolyl-tRNA synthetase 1.09857
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 1.09541
PLAU plasminogen activator, urokinase 1.09366
NAIP NLR family, apoptosis inhibitory protein 1.09226
C1QA complement component 1, q subcomponent, A chain 1.0919
POSTN periostin, osteoblast specific factor 1.0919
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.09154
FN1 fibronectin 1 1.09011
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.0894
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.0894
CCNE2 cyclin E2 1.0894
GSTA4 glutathione S-transferase alpha 4 1.08868
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.08868
MAP2K4 mitogen-activated protein kinase kinase 4 1.08833
FAS Fas cell surface death receptor 1.08797
KLK3 kallikrein-related peptidase 3 1.08726
TYMS thymidylate synthetase 1.0869
FOXO3 forkhead box O3 1.08055
IFNAR2 interferon (alpha, beta and omega) receptor 2 1.07947
DHFR dihydrofolate reductase 1.07804
TRAF3IP3 TRAF3 interacting protein 3 1.07732
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.07447
KLF6 Kruppel-like factor 6 1.07376
EDN1 endothelin 1 1.07376
IGFBP5 insulin-like growth factor binding protein 5 1.07376
REV1 REV1, polymerase (DNA directed) 1.0734
CCAR1 cell division cycle and apoptosis regulator 1 1.06771
MALT1 MALT1 paracaspase 1.06771
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 1.06771
MPO myeloperoxidase 1.06734
CALCA calcitonin-related polypeptide alpha 1.06698
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.06698
RPS6 ribosomal protein S6 1.06515
GSTA3 glutathione S-transferase alpha 3 1.0637
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 1.06152
UBE3A ubiquitin protein ligase E3A 1.06152
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.05237
POU3F3 POU class 3 homeobox 3 1.05126
PROM1 prominin 1 1.05126
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.05126
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 1.04831
EPO erythropoietin 1.04647
ISG15 ISG15 ubiquitin-like modifier 1.04538
PIR pirin (iron-binding nuclear protein) 1.04538
TJP3 tight junction protein 3 1.04501
FGF7 fibroblast growth factor 7 1.04239
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.04239
CYBB cytochrome b-245, beta polypeptide 1.04014
GJA1 gap junction protein, alpha 1, 43kDa 1.03715
CTSS cathepsin S 1.03641
HMMR hyaluronan-mediated motility receptor (RHAMM) 1.03604
XDH xanthine dehydrogenase 1.03456
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.03235
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.03235
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.03009
WEE1 WEE1 G2 checkpoint kinase 1.03009
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.02671
IRS1 insulin receptor substrate 1 1.02634
TLR1 toll-like receptor 1 1.02447
TXNIP thioredoxin interacting protein 1.02447
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.02447
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 1.0241
PECAM1 platelet/endothelial cell adhesion molecule 1 1.0241
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.02151
ARHGAP4 Rho GTPase activating protein 4 1.01776
COL3A1 collagen, type III, alpha 1 1.01701
IGFBP4 insulin-like growth factor binding protein 4 1.01549
DUSP1 dual specificity phosphatase 1 1.01512
CHEK2 checkpoint kinase 2 1.01512
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.01474
PKP2 plakophilin 2 1.01474
CD274 CD274 molecule 1.01437
BRCA1 breast cancer 1, early onset 1.01324
BCL2A1 BCL2-related protein A1 1.01025
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.01025