Motor Neuron Disease Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A neurodegenerative disease that is located_in the motor neurones. (Human Disease Ontology, DOID_231)
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Genes

23 genes associated with the Motor Neuron Disease phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ATXN2 ataxin 2
C9ORF72 chromosome 9 open reading frame 72
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
GRN granulin
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
MT-TL1 tRNA
MYH7 myosin, heavy chain 7, cardiac muscle, beta
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NEFH neurofilament, heavy polypeptide
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1
PVR poliovirus receptor
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
SOD1 superoxide dismutase 1, soluble
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
TMEM106B transmembrane protein 106B