Migraine Gene Set

Dataset GWAS Catalog SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A brain disease that is characterized by moderate to severe headaches, nausea, extreme sensitivity to light and sound and intense unilaterial throbbing or pulsing. (Human Disease Ontology, DOID_6364)
External Link https://www.ebi.ac.uk/gwas/search?query=Migraine
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Genes

36 genes associated with the Migraine phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
LRP1 low density lipoprotein receptor-related protein 1 1.00206
PRDM16 PR domain containing 16 0.786836
TRPM8 transient receptor potential cation channel, subfamily M, member 8 0.767895
FHL5 four and a half LIM domains 5 0.656287
LOC101927066 uncharacterized LOC101927066 0.637972
MEF2D myocyte enhancer factor 2D 0.602611
SUGCT succinyl-CoA:glutarate-CoA transferase 0.522843
PHACTR1 phosphatase and actin regulator 1 0.389385
ASTN2 astrotactin 2 0.377988
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) 0.342586
MRVI1 murine retrovirus integration site 1 homolog 0.314454
LEPROTL1 leptin receptor overlapping transcript-like 1 0.314454
PRKG1 protein kinase, cGMP-dependent, type I 0.295129
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.280662
MMP17 matrix metallopeptidase 17 (membrane-inserted) 0.266721
KCNK5 potassium channel, two pore domain subfamily K, member 5 0.266721
TGFB1 transforming growth factor, beta 1 0.238523
MRPL37 mitochondrial ribosomal protein L37 0.238523
WASL Wiskott-Aldrich syndrome-like 0.220915
MARCH4 membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase 0.220915
RSU1 Ras suppressor protein 1 0.165905
EYA1 EYA transcriptional coactivator and phosphatase 1 0.165905
ZDHHC6 zinc finger, DHHC-type containing 6 0.165905
ARL15 ADP-ribosylation factor-like 15 0.165905
NRP1 neuropilin 1 0.129504
NR2F2-AS1 NR2F2 antisense RNA 1 0.129504
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 0.129504
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.104568
HPSE2 heparanase 2 (inactive) 0.104568
SNX24 sorting nexin 24 0.104568
KSR2 kinase suppressor of ras 2 0.085234
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.070053
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.057619
ADRA1B adrenoceptor alpha 1B 0.057619
FRMD4A FERM domain containing 4A 0.048624
KIAA1456 KIAA1456 0.042592