Migraine with Aura Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A migraine characterized by migraine headache which is preceded or accompanied by a transient focal neurological phenomenon. (Human Disease Ontology, DOID_10024)
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Genes

63 genes associated with the Migraine with Aura phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADORA2A adenosine A2a receptor
APOE apolipoprotein E
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CASZ1 castor zinc finger 1
COMT catechol-O-methyltransferase
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD5 dopamine receptor D5
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
ESR1 estrogen receptor 1
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FASLG Fas ligand (TNF superfamily, member 6)
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IL1A interleukin 1, alpha
IL6 interleukin 6
INSR insulin receptor
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9
LDLR low density lipoprotein receptor
LTA lymphotoxin alpha
MMP2 matrix metallopeptidase 2
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NNMT nicotinamide N-methyltransferase
NOS3 nitric oxide synthase 3 (endothelial cell)
OPRM1 opioid receptor, mu 1
PRRT2 proline-rich transmembrane protein 2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
TNF tumor necrosis factor
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TYMS thymidylate synthetase