Mevalonic Acid Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A dihydroxy monocarboxylic acid comprising valeric acid having two hydroxy groups at the 3- and 5-positions together with a methyl group at the 3-position. (Chemical Entities of Biological Interest Ontology, CHEBI_25351)
External Link http://ctdbase.org/detail.go?type=chem&acc=D008798
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Genes

64 genes/proteins interacting with the chemical Mevalonic Acid from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
BBC3 BCL2 binding component 3
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BID BH3 interacting domain death agonist
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CENPF centromere protein F, 350/400kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
DGAT1 diacylglycerol O-acyltransferase 1
EDN1 endothelin 1
EGFR epidermal growth factor receptor
FBXO32 F-box protein 32
HLA-DRA major histocompatibility complex, class II, DR alpha
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
ICAM1 intercellular adhesion molecule 1
IL12B interleukin 12B
IL1B interleukin 1, beta
IL6 interleukin 6
JAK1 Janus kinase 1
JAK2 Janus kinase 2
LEP leptin
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MMP1 matrix metallopeptidase 1
MMP9 matrix metallopeptidase 9
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS2 nitric oxide synthase 2, inducible
PARP1 poly (ADP-ribose) polymerase 1
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDGFB platelet-derived growth factor beta polypeptide
PLAT plasminogen activator, tissue
PPARA peroxisome proliferator-activated receptor alpha
PRKCD protein kinase C, delta
PXN paxillin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAP1A RAP1A, member of RAS oncogene family
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RETN resistin
RHOA ras homolog family member A
RHOB ras homolog family member B
RXRA retinoid X receptor, alpha
SELE selectin E
SOD2 superoxide dismutase 2, mitochondrial
SREBF2 sterol regulatory element binding transcription factor 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TFRC transferrin receptor
TH tyrosine hydroxylase
TNF tumor necrosis factor
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
VEGFA vascular endothelial growth factor A