Metabolic Diseases Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D008659
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Genes

106 genes/proteins associated with the disease Metabolic Diseases from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
ESRRA estrogen-related receptor alpha 2.88009
CRP C-reactive protein, pentraxin-related 2.88009
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 2.88009
ETFDH electron-transferring-flavoprotein dehydrogenase 2.88009
UPB1 ureidopropionase, beta 2.88009
PPARG peroxisome proliferator-activated receptor gamma 2.88009
INS insulin 2.88009
DSG1 desmoglein 1 2.88009
CAT catalase 1.52987
FASN fatty acid synthase 1.47838
TNF tumor necrosis factor 1.46648
LEP leptin 1.41451
FOS FBJ murine osteosarcoma viral oncogene homolog 1.37761
SREBF1 sterol regulatory element binding transcription factor 1 1.36247
ADIPOQ adiponectin, C1Q and collagen domain containing 1.35589
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.35242
ACACB acetyl-CoA carboxylase beta 1.3311
PPARA peroxisome proliferator-activated receptor alpha 1.33022
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.3228
NOS3 nitric oxide synthase 3 (endothelial cell) 1.31956
GPX1 glutathione peroxidase 1 1.29812
ATF4 activating transcription factor 4 1.29657
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.28672
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.27689
SOD1 superoxide dismutase 1, soluble 1.2744
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 1.26669
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 1.26113
CCL2 chemokine (C-C motif) ligand 2 1.25525
LDLR low density lipoprotein receptor 1.25494
APOA4 apolipoprotein A-IV 1.24181
FDPS farnesyl diphosphate synthase 1.23201
APOE apolipoprotein E 1.23074
TGFB1 transforming growth factor, beta 1 1.22048
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.21435
DUSP1 dual specificity phosphatase 1 1.21108
LPL lipoprotein lipase 1.20262
ALG9 ALG9, alpha-1,2-mannosyltransferase 1.19966
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 1.18126
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.17993
APOB apolipoprotein B 1.1786
PRDX1 peroxiredoxin 1 1.17563
GSR glutathione reductase 1.17464
IRS1 insulin receptor substrate 1 1.17101
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.16236
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.1485
PRRC2A proline-rich coiled-coil 2A 1.142
SP1 Sp1 transcription factor 1.142
CPT1A carnitine palmitoyltransferase 1A (liver) 1.13793
APOC3 apolipoprotein C-III 1.13758
GSTP1 glutathione S-transferase pi 1 1.13689
LCAT lecithin-cholesterol acyltransferase 1.13449
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.13313
EIF5 eukaryotic translation initiation factor 5 1.12906
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.12703
IL1B interleukin 1, beta 1.12703
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 1.12254
LIPC lipase, hepatic 1.12014
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 1.11741
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.11325
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.11151
VCAM1 vascular cell adhesion molecule 1 1.10699
SIRT1 sirtuin 1 1.10388
ALB albumin 1.10317
HADH hydroxyacyl-CoA dehydrogenase 1.09751
IL6 interleukin 6 1.09646
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.09541
JAK1 Janus kinase 1 1.09083
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 1.09083
EGR1 early growth response 1 1.08407
H2AFX H2A histone family, member X 1.07983
GCK glucokinase (hexokinase 4) 1.07875
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 1.0784
FGD4 FYVE, RhoGEF and PH domain containing 4 1.0734
HNF4A hepatocyte nuclear factor 4, alpha 1.07305
ACOT4 acyl-CoA thioesterase 4 1.06917
MPO myeloperoxidase 1.06771
IGF1 insulin-like growth factor 1 (somatomedin C) 1.06625
PCP4L1 Purkinje cell protein 4 like 1 1.06515
VEGFA vascular endothelial growth factor A 1.0637
JUN jun proto-oncogene 1.06297
DDIT3 DNA-damage-inducible transcript 3 1.06008
GPX4 glutathione peroxidase 4 1.0561
SOD2 superoxide dismutase 2, mitochondrial 1.05461
PGK1 phosphoglycerate kinase 1 1.05423
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.05237
GNAS GNAS complex locus 1.04684
MMP2 matrix metallopeptidase 2 1.04647
POR P450 (cytochrome) oxidoreductase 1.04501
UBE2D3 ubiquitin-conjugating enzyme E2D 3 1.04465
GFRA2 GDNF family receptor alpha 2 1.04088
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 1.04051
APOA5 apolipoprotein A-V 1.03419
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.03382
CDC34 cell division cycle 34 1.03345
PRIM2 primase, DNA, polypeptide 2 (58kDa) 1.03308
JUND jun D proto-oncogene 1.03159
SDS serine dehydratase 1.02971
IFNG interferon, gamma 1.02896
ABHD4 abhydrolase domain containing 4 1.02634
TUBGCP4 tubulin, gamma complex associated protein 4 1.02596
BCL2 B-cell CLL/lymphoma 2 1.02447
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.02336
MAPK14 mitogen-activated protein kinase 14 1.01852
CCNL1 cyclin L1 1.01587
CYBB cytochrome b-245, beta polypeptide 1.01099
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.01025