Mesothelioma Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D008654
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Genes

318 genes/proteins associated with the disease Mesothelioma from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 2.88009
FGF2 fibroblast growth factor 2 (basic) 2.88009
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 2.88009
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 2.88009
CDKN2A cyclin-dependent kinase inhibitor 2A 2.88009
MTOR mechanistic target of rapamycin (serine/threonine kinase) 2.88009
GSN gelsolin 2.88009
GSTM1 glutathione S-transferase mu 1 2.88009
NME2 NME/NM23 nucleoside diphosphate kinase 2 2.88009
EGR1 early growth response 1 2.88009
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 2.88009
PUF60 poly-U binding splicing factor 60KDa 2.88009
DIO2 deiodinase, iodothyronine, type II 2.88009
TP53 tumor protein p53 2.88009
NF2 neurofibromin 2 (merlin) 2.88009
SOD2 superoxide dismutase 2, mitochondrial 2.88009
EGFR epidermal growth factor receptor 2.88009
MUC1 mucin 1, cell surface associated 2.88009
PDGFA platelet-derived growth factor alpha polypeptide 2.88009
FHIT fragile histidine triad 2.88009
MSLN mesothelin 2.88009
GDF10 growth differentiation factor 10 2.88009
SYK spleen tyrosine kinase 2.88009
IFNG interferon, gamma 2.88009
ITLN1 intelectin 1 (galactofuranose binding) 2.88009
EID1 EP300 interacting inhibitor of differentiation 1 2.88009
APC adenomatous polyposis coli 2.88009
ESR1 estrogen receptor 1 2.88009
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.88009
MYO18B myosin XVIIIB 2.88009
SPP1 secreted phosphoprotein 1 2.88009
CAT catalase 2.88009
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 2.88009
PGR progesterone receptor 2.88009
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 2.88009
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 2.88009
GPC3 glypican 3 2.88009
FGF1 fibroblast growth factor 1 (acidic) 2.88009
PDGFC platelet derived growth factor C 2.88009
TXNRD1 thioredoxin reductase 1 2.88009
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.93292
CCND1 cyclin D1 1.92785
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.91317
FAS Fas cell surface death receptor 1.87892
BCL2L1 BCL2-like 1 1.85046
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.82656
BIRC5 baculoviral IAP repeat containing 5 1.79885
BCL2 B-cell CLL/lymphoma 2 1.78682
BAX BCL2-associated X protein 1.78302
DDIT3 DNA-damage-inducible transcript 3 1.78283
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.7652
RB1 retinoblastoma 1 1.76424
MCL1 myeloid cell leukemia 1 1.7554
VEGFA vascular endothelial growth factor A 1.74862
MAPK1 mitogen-activated protein kinase 1 1.72633
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.72055
BID BH3 interacting domain death agonist 1.71748
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.71399
CCND3 cyclin D3 1.71091
ATF3 activating transcription factor 3 1.69448
H2AFX H2A histone family, member X 1.68718
E2F1 E2F transcription factor 1 1.68337
ATF4 activating transcription factor 4 1.67633
MAPK3 mitogen-activated protein kinase 3 1.67483
GADD45A growth arrest and DNA-damage-inducible, alpha 1.63094
IL10 interleukin 10 1.62736
BIRC2 baculoviral IAP repeat containing 2 1.62535
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.61944
CCNB1 cyclin B1 1.61342
MAPK14 mitogen-activated protein kinase 14 1.60711
BRCA1 breast cancer 1, early onset 1.60571
JUN jun proto-oncogene 1.60477
PCNA proliferating cell nuclear antigen 1.58842
CDK1 cyclin-dependent kinase 1 1.58444
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.58137
TGFB1 transforming growth factor, beta 1 1.56337
CDK4 cyclin-dependent kinase 4 1.55846
RPS6 ribosomal protein S6 1.55574
TYMS thymidylate synthetase 1.54232
EGF epidermal growth factor 1.53603
COL1A1 collagen, type I, alpha 1 1.52338
CFLAR CASP8 and FADD-like apoptosis regulator 1.5181
CXCL8 chemokine (C-X-C motif) ligand 8 1.51708
MKI67 marker of proliferation Ki-67 1.5108
TNF tumor necrosis factor 1.50448
MMP9 matrix metallopeptidase 9 1.50423
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.49711
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.48967
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.48941
GSK3B glycogen synthase kinase 3 beta 1.47711
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.47608
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.46961
KLK3 kallikrein-related peptidase 3 1.46858
MPO myeloperoxidase 1.46832
CD44 CD44 molecule (Indian blood group) 1.46781
TYMP thymidine phosphorylase 1.46198
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.46041
IL6 interleukin 6 1.45458
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.44327
CCNA2 cyclin A2 1.43564
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.43455
PARP1 poly (ADP-ribose) polymerase 1 1.42831
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.42696
BBC3 BCL2 binding component 3 1.42401
CDK2 cyclin-dependent kinase 2 1.42293
MAPK8 mitogen-activated protein kinase 8 1.42129
SAT1 spermidine/spermine N1-acetyltransferase 1 1.41911
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.41802
MDK midkine (neurite growth-promoting factor 2) 1.40925
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.4026
FADD Fas (TNFRSF6)-associated via death domain 1.3998
DIABLO diablo, IAP-binding mitochondrial protein 1.38918
FASLG Fas ligand (TNF superfamily, member 6) 1.38185
HRAS Harvey rat sarcoma viral oncogene homolog 1.37902
ERCC1 excision repair cross-complementation group 1 1.37874
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.37648
XBP1 X-box binding protein 1 1.37475
ERBB2 erb-b2 receptor tyrosine kinase 2 1.37303
TRIB3 tribbles pseudokinase 3 1.37103
MAP2K3 mitogen-activated protein kinase kinase 3 1.37047
SP1 Sp1 transcription factor 1.36763
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.36332
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.35386
FLT1 fms-related tyrosine kinase 1 1.35184
IL1B interleukin 1, beta 1.34664
MMP2 matrix metallopeptidase 2 1.34576
COL1A2 collagen, type I, alpha 2 1.34459
FOXO3 forkhead box O3 1.34227
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.34227
CD40LG CD40 ligand 1.33966
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.33612
KLF6 Kruppel-like factor 6 1.33553
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.32132
BIN1 bridging integrator 1 1.31686
CYCS cytochrome c, somatic 1.31566
LDLR low density lipoprotein receptor 1.31178
PECAM1 platelet/endothelial cell adhesion molecule 1 1.31119
RBM17 RNA binding motif protein 17 1.30727
IGFBP4 insulin-like growth factor binding protein 4 1.30208
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.30208
CDC25A cell division cycle 25A 1.29905
COL4A2 collagen, type IV, alpha 2 1.29812
TERT telomerase reverse transcriptase 1.29657
EMP3 epithelial membrane protein 3 1.29348
RPS27L ribosomal protein S27-like 1.29348
IL1A interleukin 1, alpha 1.29287
MAP2K2 mitogen-activated protein kinase kinase 2 1.29256
CTGF connective tissue growth factor 1.29133
HMOX1 heme oxygenase 1 1.29103
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.28641
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.2861
FOS FBJ murine osteosarcoma viral oncogene homolog 1.28487
CSF1 colony stimulating factor 1 (macrophage) 1.28456
CDC42 cell division cycle 42 1.28456
BAD BCL2-associated agonist of cell death 1.28241
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.27657
CCL2 chemokine (C-C motif) ligand 2 1.27626
BAK1 BCL2-antagonist/killer 1 1.2707
KIF20A kinesin family member 20A 1.26825
F3 coagulation factor III (thromboplastin, tissue factor) 1.25776
BECN1 beclin 1, autophagy related 1.25276
TRAF1 TNF receptor-associated factor 1 1.25245
CTSB cathepsin B 1.25028
LCN2 lipocalin 2 1.25028
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.24781
IL4 interleukin 4 1.24687
ATM ATM serine/threonine kinase 1.24338
HSPA1A heat shock 70kDa protein 1A 1.24275
STK17A serine/threonine kinase 17a 1.24275
CAV1 caveolin 1, caveolae protein, 22kDa 1.2415
HSPB1 heat shock 27kDa protein 1 1.2415
C3 complement component 3 1.2415
LMNA lamin A/C 1.23775
DPYD dihydropyrimidine dehydrogenase 1.23775
AURKA aurora kinase A 1.23552
CCNE1 cyclin E1 1.23106
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.22948
FOSL1 FOS-like antigen 1 1.22948
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.22566
RBM14 RNA binding motif protein 14 1.22469
PRKCD protein kinase C, delta 1.2208
PLAU plasminogen activator, urokinase 1.21567
FN1 fibronectin 1 1.20295
BIRC3 baculoviral IAP repeat containing 3 1.19639
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 1.19607
IGFBP6 insulin-like growth factor binding protein 6 1.19312
CFD complement factor D (adipsin) 1.18981
ILF3 interleukin enhancer binding factor 3, 90kDa 1.1862
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.18126
CXCL3 chemokine (C-X-C motif) ligand 3 1.18059
CDC20 cell division cycle 20 1.17926
MAP2K1 mitogen-activated protein kinase kinase 1 1.17926
PTK2 protein tyrosine kinase 2 1.17728
HIST1H4C histone cluster 1, H4c 1.17629
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.17431
IGF1 insulin-like growth factor 1 (somatomedin C) 1.17
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.16567
PTEN phosphatase and tensin homolog 1.16567
EIF4E eukaryotic translation initiation factor 4E 1.16567
GDF15 growth differentiation factor 15 1.16567
G6PD glucose-6-phosphate dehydrogenase 1.16434
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.16269
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.16203
RRM2 ribonucleotide reductase M2 1.15933
PPIB peptidylprolyl isomerase B (cyclophilin B) 1.15729
COL6A2 collagen, type VI, alpha 2 1.15729
CXCL2 chemokine (C-X-C motif) ligand 2 1.15729
VIM vimentin 1.1556
CCNB2 cyclin B2 1.15526
COL4A1 collagen, type IV, alpha 1 1.15425
IFI30 interferon, gamma-inducible protein 30 1.1485
IL1RN interleukin 1 receptor antagonist 1.14747
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.14713
MAP2K6 mitogen-activated protein kinase kinase 6 1.14302
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.142
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 1.1403
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.13963
AREG amphiregulin 1.13621
PALLD palladin, cytoskeletal associated protein 1.13552
PDPK1 3-phosphoinositide dependent protein kinase 1 1.13518
PKN2 protein kinase N2 1.13143
CCNG2 cyclin G2 1.12737
PDLIM7 PDZ and LIM domain 7 (enigma) 1.12703
RAB8A RAB8A, member RAS oncogene family 1.12426
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 1.12391
BCL2L2 BCL2-like 2 1.12323
TMSB4X thymosin beta 4, X-linked 1.12288
MGMT O-6-methylguanine-DNA methyltransferase 1.12185
BTG2 BTG family, member 2 1.12185
S100A4 S100 calcium binding protein A4 1.11945
VCAM1 vascular cell adhesion molecule 1 1.11571
PPL periplakin 1.11536
BTG1 B-cell translocation gene 1, anti-proliferative 1.11466
ACTA2 actin, alpha 2, smooth muscle, aorta 1.1122
FDXR ferredoxin reductase 1.11116
CD59 CD59 molecule, complement regulatory protein 1.11116
ALDOA aldolase A, fructose-bisphosphate 1.10977
PROCR protein C receptor, endothelial 1.10353
TUBB tubulin, beta class I 1.10353
NOLC1 nucleolar and coiled-body phosphoprotein 1 1.10353
UBE2C ubiquitin-conjugating enzyme E2C 1.10246
NRP1 neuropilin 1 1.10246
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 1.09611
HSPE1 heat shock 10kDa protein 1 1.09541
LPAR1 lysophosphatidic acid receptor 1 1.09226
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.09083
PTTG1 pituitary tumor-transforming 1 1.09047
NAIP NLR family, apoptosis inhibitory protein 1.08975
POSTN periostin, osteoblast specific factor 1.08868
C1QA complement component 1, q subcomponent, A chain 1.08868
PSAP prosaposin 1.08868
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.08584
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.08584
DUSP10 dual specificity phosphatase 10 1.08513
SOD1 superoxide dismutase 1, soluble 1.08513
EWSR1 EWS RNA-binding protein 1 1.08337
AXL AXL receptor tyrosine kinase 1.08196
RUNX1 runt-related transcription factor 1 1.0784
RFC3 replication factor C (activator 1) 3, 38kDa 1.07804
IGFBP3 insulin-like growth factor binding protein 3 1.07518
MT2A metallothionein 2A 1.07518
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.07128
ATP7A ATPase, Cu++ transporting, alpha polypeptide 1.07128
IGFBP5 insulin-like growth factor binding protein 5 1.07022
CSF1R colony stimulating factor 1 receptor 1.06844
GPX1 glutathione peroxidase 1 1.06479
PPARD peroxisome proliferator-activated receptor delta 1.06406
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.06297
TTK TTK protein kinase 1.06152
FHL1 four and a half LIM domains 1 1.06116
GSTT1 glutathione S-transferase theta 1 1.06008
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.05972
VCAN versican 1.05828
FEN1 flap structure-specific endonuclease 1 1.05498
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.05349
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 1.05349
CDC25C cell division cycle 25C 1.04904
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 1.04831
MPZL1 myelin protein zero-like 1 1.04757
STMN1 stathmin 1 1.04684
TIMP3 TIMP metallopeptidase inhibitor 3 1.04684
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.04501
CDC14B cell division cycle 14B 1.04201
PRC1 protein regulator of cytokinesis 1 1.04201
EXT1 exostosin glycosyltransferase 1 1.04201
TOP2A topoisomerase (DNA) II alpha 170kDa 1.04051
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 1.03901
TP53BP1 tumor protein p53 binding protein 1 1.03827
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 1.03678
IFI6 interferon, alpha-inducible protein 6 1.03678
TPP2 tripeptidyl peptidase II 1.03678
DEK DEK proto-oncogene 1.03641
GLRX glutaredoxin (thioltransferase) 1.03604
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.03308
GJA1 gap junction protein, alpha 1, 43kDa 1.03308
PRKDC protein kinase, DNA-activated, catalytic polypeptide 1.03308
SOX4 SRY (sex determining region Y)-box 4 1.03271
DUSP6 dual specificity phosphatase 6 1.03271
ATG7 autophagy related 7 1.03197
AVPI1 arginine vasopressin-induced 1 1.03159
GADD45B growth arrest and DNA-damage-inducible, beta 1.03084
CLU clusterin 1.03046
EPCAM epithelial cell adhesion molecule 1.03009
KEAP1 kelch-like ECH-associated protein 1 1.02858
TFAM transcription factor A, mitochondrial 1.02373
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.02114
TXNIP thioredoxin interacting protein 1.02114
IL4R interleukin 4 receptor 1.01701
MED4 mediator complex subunit 4 1.01474
CIZ1 CDKN1A interacting zinc finger protein 1 1.01474
COL3A1 collagen, type III, alpha 1 1.01361
ALDOC aldolase C, fructose-bisphosphate 1.01249
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.01249
CD274 CD274 molecule 1.01174
RRAS related RAS viral (r-ras) oncogene homolog 1.01174
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.01174
CHEK2 checkpoint kinase 2 1.01174
INSIG1 insulin induced gene 1 1.01137