Malignant mesothelioma of pleura_Pleura_GSE2549 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2549
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Genes

600 genes differentially expressed during Malignant mesothelioma of pleura_Pleura_GSE2549 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
STX6 syntaxin 6 2.88916
TSSC1 tumor suppressing subtransferable candidate 1 2.69299
CLINT1 clathrin interactor 1 2.41708
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 2.41048
TFE3 transcription factor binding to IGHM enhancer 3 2.40527
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 2.39035
ATF2 activating transcription factor 2 2.38832
ARMC1 armadillo repeat containing 1 2.37991
CDYL chromodomain protein, Y-like 2.36786
THUMPD1 THUMP domain containing 1 2.36749
LARP4B La ribonucleoprotein domain family, member 4B 2.34862
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 2.33559
RIOK3 RIO kinase 3 2.32757
SGPL1 sphingosine-1-phosphate lyase 1 2.32293
NRD1 nardilysin (N-arginine dibasic convertase) 2.31933
GTF2IRD1 GTF2I repeat domain containing 1 2.31596
SLC38A10 solute carrier family 38, member 10 2.30013
BAG6 BCL2-associated athanogene 6 2.29736
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 2.28044
STRADA STE20-related kinase adaptor alpha 2.26781
COPB1 coatomer protein complex, subunit beta 1 2.25814
RNASEH1 ribonuclease H1 2.24961
NONO non-POU domain containing, octamer-binding 2.24339
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.24186
MTDH metadherin 2.22645
TMED3 transmembrane emp24 protein transport domain containing 3 2.21646
PALB2 partner and localizer of BRCA2 2.20751
ATXN10 ataxin 10 2.20107
ZNF706 zinc finger protein 706 2.19886
RNF10 ring finger protein 10 2.19826
C2CD3 C2 calcium-dependent domain containing 3 2.18507
IPO7 importin 7 2.18483
TMCO1 transmembrane and coiled-coil domains 1 2.1825
RNF14 ring finger protein 14 2.17746
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.17411
TOPBP1 topoisomerase (DNA) II binding protein 1 2.1535
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 2.13139
SMC4 structural maintenance of chromosomes 4 2.1275
TP53BP1 tumor protein p53 binding protein 1 2.12506
MTX1 metaxin 1 2.12399
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 2.11511
ELAVL1 ELAV like RNA binding protein 1 2.08144
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 2.07839
CUL4B cullin 4B 2.06984
OBSL1 obscurin-like 1 2.05789
GMFB glia maturation factor, beta 2.05782
KDM5B lysine (K)-specific demethylase 5B 2.04175
UBE2Z ubiquitin-conjugating enzyme E2Z 2.02863
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) 2.01701
KLF7 Kruppel-like factor 7 (ubiquitous) 2.01245
NKIRAS2 NFKB inhibitor interacting Ras-like 2 2.00826
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 2.00103
DVL3 dishevelled segment polarity protein 3 1.99828
ATP13A1 ATPase type 13A1 1.99433
BPTF bromodomain PHD finger transcription factor 1.9874
TRMT61B tRNA methyltransferase 61B 1.98445
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 1.97715
AAMP angio-associated, migratory cell protein 1.97541
FXN frataxin 1.97344
UBAP2 ubiquitin associated protein 2 1.9715
HYOU1 hypoxia up-regulated 1 1.95159
ZNF24 zinc finger protein 24 1.94784
CHIC2 cysteine-rich hydrophobic domain 2 1.94249
TCTN3 tectonic family member 3 1.93767
ACSL3 acyl-CoA synthetase long-chain family member 3 1.91067
DNAAF5 dynein, axonemal, assembly factor 5 1.90951
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 1.90761
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) 1.90624
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 1.90152
TMEM41B transmembrane protein 41B 1.90104
UCK2 uridine-cytidine kinase 2 1.89824
COASY CoA synthase 1.88191
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) 1.87761
CHD4 chromodomain helicase DNA binding protein 4 1.87609
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 1.87108
MBD1 methyl-CpG binding domain protein 1 1.86613
NRF1 nuclear respiratory factor 1 1.86576
QARS glutaminyl-tRNA synthetase 1.86304
NUP50 nucleoporin 50kDa 1.86256
CYLD cylindromatosis (turban tumor syndrome) 1.86115
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 1.8597
PABPC3 poly(A) binding protein, cytoplasmic 3 1.85703
MRPL11 mitochondrial ribosomal protein L11 1.85588
UBE2A ubiquitin-conjugating enzyme E2A 1.85484
ARF3 ADP-ribosylation factor 3 1.85415
URI1 URI1, prefoldin-like chaperone 1.85011
RIC8A RIC8 guanine nucleotide exchange factor A 1.84572
ZNF207 zinc finger protein 207 1.84243
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 1.83681
HELZ helicase with zinc finger 1.8329
RACGAP1 Rac GTPase activating protein 1 1.83115
ZNF185 zinc finger protein 185 (LIM domain) 1.83099
PA2G4 proliferation-associated 2G4, 38kDa 1.82705
NSUN5 NOP2/Sun domain family, member 5 1.81967
TMEM50B transmembrane protein 50B 1.8138
EIF4A1 eukaryotic translation initiation factor 4A1 1.81006
DIABLO diablo, IAP-binding mitochondrial protein 1.79499
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 1.7945
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 1.78945
KIAA0368 KIAA0368 1.78896
GLUD1 glutamate dehydrogenase 1 1.78155
DPP8 dipeptidyl-peptidase 8 1.77576
HIGD2A HIG1 hypoxia inducible domain family, member 2A 1.77572
POTEKP POTE ankyrin domain family, member K, pseudogene 1.77559
CUTA cutA divalent cation tolerance homolog (E. coli) 1.7753
ARMCX3 armadillo repeat containing, X-linked 3 1.77528
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A 1.77443
PABPN1 poly(A) binding protein, nuclear 1 1.77394
NME2 NME/NM23 nucleoside diphosphate kinase 2 1.77387
MRS2 MRS2 magnesium transporter 1.77383
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 1.77372
NKRF NFKB repressing factor 1.77333
ADPGK ADP-dependent glucokinase 1.77114
TPGS2 tubulin polyglutamylase complex subunit 2 1.76775
BCL2L1 BCL2-like 1 1.76238
TEAD4 TEA domain family member 4 1.76165
STAU1 staufen double-stranded RNA binding protein 1 1.7561
HAUS7 HAUS augmin-like complex, subunit 7 1.75511
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 1.74841
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 1.74828
KIAA0556 KIAA0556 1.74335
CANT1 calcium activated nucleotidase 1 1.73759
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 1.73681
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 1.7368
AUP1 ancient ubiquitous protein 1 1.73411
FUBP1 far upstream element (FUSE) binding protein 1 1.73265
PRPF4B pre-mRNA processing factor 4B 1.73251
HNRNPL heterogeneous nuclear ribonucleoprotein L 1.73074
INTS6 integrator complex subunit 6 1.72741
SPAG9 sperm associated antigen 9 1.72614
SCAND1 SCAN domain containing 1 1.7247
PTBP2 polypyrimidine tract binding protein 2 1.72432
PPIC peptidylprolyl isomerase C (cyclophilin C) 1.72263
YEATS4 YEATS domain containing 4 1.72022
LINC00597 long intergenic non-protein coding RNA 597 1.71859
ZC3H11A zinc finger CCCH-type containing 11A 1.71633
UBE2G1 ubiquitin-conjugating enzyme E2G 1 1.71017
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 1.70209
ECT2 epithelial cell transforming 2 1.70045
HMMR hyaluronan-mediated motility receptor (RHAMM) 1.70003
DLG1 discs, large homolog 1 (Drosophila) 1.69997
PRPF8 pre-mRNA processing factor 8 1.69807
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) 1.69621
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 1.68948
WDR70 WD repeat domain 70 1.68807
LARS leucyl-tRNA synthetase 1.68276
SART3 squamous cell carcinoma antigen recognized by T cells 3 1.68043
UBE2J1 ubiquitin-conjugating enzyme E2, J1 1.67871
KIAA0355 KIAA0355 1.6787
WBP4 WW domain binding protein 4 1.67792
PGLS 6-phosphogluconolactonase 1.67687
PKN2 protein kinase N2 1.67599
CREBZF CREB/ATF bZIP transcription factor 1.67568
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 1.67532
AP2B1 adaptor-related protein complex 2, beta 1 subunit 1.67354
CDR2 cerebellar degeneration-related protein 2, 62kDa 1.67006
TARDBP TAR DNA binding protein 1.66969
TNPO1 transportin 1 1.66912
PHIP pleckstrin homology domain interacting protein 1.66411
VAT1 vesicle amine transport 1 1.66291
PHF21A PHD finger protein 21A 1.6575
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 1.65497
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 1.65447
CEP57 centrosomal protein 57kDa 1.65287
REC8 REC8 meiotic recombination protein 1.65146
ADRM1 adhesion regulating molecule 1 1.64933
PRPS2 phosphoribosyl pyrophosphate synthetase 2 1.64537
PBK PDZ binding kinase 1.64055
GANAB glucosidase, alpha; neutral AB 1.63733
ZNF354A zinc finger protein 354A 1.63576
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 1.62958
CHPF chondroitin polymerizing factor 1.62676
UBE2G2 ubiquitin-conjugating enzyme E2G 2 1.62559
XKR8 XK, Kell blood group complex subunit-related family, member 8 1.61887
TMEM185B transmembrane protein 185B 1.61674
COX11 COX11 cytochrome c oxidase copper chaperone 1.60974
PARP1 poly (ADP-ribose) polymerase 1 1.60938
TRIM37 tripartite motif containing 37 1.60823
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 1.60398
S100A10 S100 calcium binding protein A10 1.60229
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 1.60184
CKAP2 cytoskeleton associated protein 2 1.59858
GSS glutathione synthetase 1.59529
LMNA lamin A/C 1.59484
CRAT carnitine O-acetyltransferase 1.59248
SSR1 signal sequence receptor, alpha 1.59019
ATG4B autophagy related 4B, cysteine peptidase 1.58785
TRIP13 thyroid hormone receptor interactor 13 1.5832
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 1.58188
USP11 ubiquitin specific peptidase 11 1.58188
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.57994
DOLK dolichol kinase 1.5771
MRPL23 mitochondrial ribosomal protein L23 1.57702
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.57685
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.57636
VMA21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) 1.57435
PMF1 polyamine-modulated factor 1 1.57129
CACYBP calcyclin binding protein 1.56971
FDPS farnesyl diphosphate synthase 1.56829
FAM102A family with sequence similarity 102, member A 1.568
SMG9 SMG9 nonsense mediated mRNA decay factor 1.56605
NEK1 NIMA-related kinase 1 1.56176
ETNK1 ethanolamine kinase 1 1.5609
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 1.56087
GOLGA4 golgin A4 1.55889
IGSF3 immunoglobulin superfamily, member 3 1.55832
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 1.55156
C12ORF10 chromosome 12 open reading frame 10 1.55009
SERBP1 SERPINE1 mRNA binding protein 1 1.54826
MAN2C1 mannosidase, alpha, class 2C, member 1 1.54792
MTO1 mitochondrial tRNA translation optimization 1 1.54491
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 1.5399
PUM2 pumilio RNA-binding family member 2 1.53816
USP8 ubiquitin specific peptidase 8 1.53718
SND1 staphylococcal nuclease and tudor domain containing 1 1.53689
TGOLN2 trans-golgi network protein 2 1.53687
MGEA5 meningioma expressed antigen 5 (hyaluronidase) 1.53628
KIAA0907 KIAA0907 1.53284
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 1.53195
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 1.53
TUBB6 tubulin, beta 6 class V 1.52747
XPC xeroderma pigmentosum, complementation group C 1.52636
CNPY3 canopy FGF signaling regulator 3 1.52582
DNM1L dynamin 1-like 1.52497
ZNF281 zinc finger protein 281 1.5219
METTL22 methyltransferase like 22 1.52139
C19ORF53 chromosome 19 open reading frame 53 1.51921
UBB ubiquitin B 1.51675
SORD sorbitol dehydrogenase 1.51661
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 1.51511
PMS2P1 postmeiotic segregation increased 2 pseudogene 1 1.51324
HINT1 histidine triad nucleotide binding protein 1 1.5086
STX16 syntaxin 16 1.5082
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 1.50774
TTC4 tetratricopeptide repeat domain 4 1.50677
BMS1 BMS1 ribosome biogenesis factor 1.50088
TPI1 triosephosphate isomerase 1 1.50004
XPO6 exportin 6 1.49854
RAI14 retinoic acid induced 14 1.49782
KIAA0509 uncharacterized LOC57242 1.49598
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2 1.49507
VAX2 ventral anterior homeobox 2 1.49499
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 1.49404
UROS uroporphyrinogen III synthase 1.49099
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 1.49065
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa 1.48944
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 1.4889
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 1.48853
PRSS50 protease, serine, 50 1.48694
XPOT exportin, tRNA 1.4868
RAD17 RAD17 homolog (S. pombe) 1.48585
POT1 protection of telomeres 1 1.47878
HLA-A major histocompatibility complex, class I, A 1.47863
PEX7 peroxisomal biogenesis factor 7 1.47719
EEF1G eukaryotic translation elongation factor 1 gamma 1.47671
KNTC1 kinetochore associated 1 1.47599
TOMM34 translocase of outer mitochondrial membrane 34 1.47553
DONSON downstream neighbor of SON 1.47394
SMAD4 SMAD family member 4 1.47126
PMM2 phosphomannomutase 2 1.47116
KIAA0101 KIAA0101 1.46929
FBXL12 F-box and leucine-rich repeat protein 12 1.4673
TMEM223 transmembrane protein 223 1.46668
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.46656
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 1.46361
DRD5 dopamine receptor D5 1.45925
CCDC86 coiled-coil domain containing 86 1.45787
FKBP1A FK506 binding protein 1A, 12kDa 1.4574
PARN poly(A)-specific ribonuclease 1.4561
GRB10 growth factor receptor-bound protein 10 1.45572
PFDN2 prefoldin subunit 2 1.45387
TPRKB TP53RK binding protein 1.4532
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 1.45278
METTL13 methyltransferase like 13 1.44948
TTF1 transcription termination factor, RNA polymerase I 1.44726
SEPT10 septin 10 1.44651
KEAP1 kelch-like ECH-associated protein 1 1.44618
LRRC40 leucine rich repeat containing 40 1.44392
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 1.44062
USF2 upstream transcription factor 2, c-fos interacting 1.43936
LRRC1 leucine rich repeat containing 1 1.43274
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 1.43255
LPCAT4 lysophosphatidylcholine acyltransferase 4 1.43109
KAT2A K(lysine) acetyltransferase 2A 1.43
PARP6 poly (ADP-ribose) polymerase family, member 6 1.42875
TRAP1 TNF receptor-associated protein 1 1.42863
AMACR alpha-methylacyl-CoA racemase 1.4284
NCK2 NCK adaptor protein 2 1.42783
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1 1.4277
RNF38 ring finger protein 38 1.42739
PTK2 protein tyrosine kinase 2 1.42634
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 1.42551
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene 1.42179
SYP synaptophysin 1.42174
STX17 syntaxin 17 1.42156
CANX calnexin 1.4186
PUS7 pseudouridylate synthase 7 (putative) 1.41613
BRAP BRCA1 associated protein 1.41593
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 1.41562
MRPS30 mitochondrial ribosomal protein S30 1.4126

decreased expression

Symbol Name Standardized Value
PARL presenilin associated, rhomboid-like -2.99786
PTEN phosphatase and tensin homolog -2.59486
MGST2 microsomal glutathione S-transferase 2 -2.58274
HADH hydroxyacyl-CoA dehydrogenase -2.54722
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) -2.50377
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -2.50173
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -2.48872
STX8 syntaxin 8 -2.45131
METTL18 methyltransferase like 18 -2.40652
RNF7 ring finger protein 7 -2.37831
HHEX hematopoietically expressed homeobox -2.3283
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -2.32461
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 -2.27734
HECA headcase homolog (Drosophila) -2.25443
DIO2 deiodinase, iodothyronine, type II -2.24082
LINC00341 long intergenic non-protein coding RNA 341 -2.20967
C6 complement component 6 -2.20021
SOX10 SRY (sex determining region Y)-box 10 -2.18783
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.17577
ANKRD46 ankyrin repeat domain 46 -2.16097
EMC3 ER membrane protein complex subunit 3 -2.14836
MYL4 myosin, light chain 4, alkali; atrial, embryonic -2.14529
GAPVD1 GTPase activating protein and VPS9 domains 1 -2.1398
TOR1B torsin family 1, member B (torsin B) -2.12609
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -2.10273
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) -2.09157
TBC1D10B TBC1 domain family, member 10B -2.08916
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) -2.07606
RPIA ribose 5-phosphate isomerase A -2.07255
METTL4 methyltransferase like 4 -2.07034
NCOA4 nuclear receptor coactivator 4 -2.06773
MLX MLX, MAX dimerization protein -2.06274
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -2.05593
TSC1 tuberous sclerosis 1 -2.05559
FBXL7 F-box and leucine-rich repeat protein 7 -2.0462
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) -2.03316
ZNF638 zinc finger protein 638 -2.0203
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -2.0168
CLN5 ceroid-lipofuscinosis, neuronal 5 -2.01598
CLP1 cleavage and polyadenylation factor I subunit 1 -2.01559
ANAPC15 anaphase promoting complex subunit 15 -2.01548
RPL22 ribosomal protein L22 -2.01276
ERLIN2 ER lipid raft associated 2 -2.01208
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -2.00706
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.00281
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.00045
SPAG1 sperm associated antigen 1 -1.98805
RPL27A ribosomal protein L27a -1.97511
AKR1C1 aldo-keto reductase family 1, member C1 -1.95545
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -1.95011
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -1.94798
MAN1A1 mannosidase, alpha, class 1A, member 1 -1.94067
KATNA1 katanin p60 (ATPase containing) subunit A 1 -1.93616
HEXB hexosaminidase B (beta polypeptide) -1.9337
RAB22A RAB22A, member RAS oncogene family -1.91571
MPC1 mitochondrial pyruvate carrier 1 -1.91129
DBR1 debranching RNA lariats 1 -1.9032
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) -1.89693
HBG2 hemoglobin, gamma G -1.89386
TM2D3 TM2 domain containing 3 -1.89192
RPL9 ribosomal protein L9 -1.88807
CCDC59 coiled-coil domain containing 59 -1.88636
ACACB acetyl-CoA carboxylase beta -1.87799
STXBP1 syntaxin binding protein 1 -1.8762
TMEM59 transmembrane protein 59 -1.84923
SELP selectin P (granule membrane protein 140kDa, antigen CD62) -1.84639
WFS1 Wolfram syndrome 1 (wolframin) -1.8447
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -1.83861
CCNH cyclin H -1.82806
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -1.82646
HBB hemoglobin, beta -1.82401
ETFDH electron-transferring-flavoprotein dehydrogenase -1.82079
CIDEC cell death-inducing DFFA-like effector c -1.8198
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -1.81072
SAP18 Sin3A-associated protein, 18kDa -1.80674
MTMR9 myotubularin related protein 9 -1.80292
ACSL1 acyl-CoA synthetase long-chain family member 1 -1.79006
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -1.78842
CTR9 CTR9, Paf1/RNA polymerase II complex component -1.78759
PDCD2 programmed cell death 2 -1.78589
GCC1 GRIP and coiled-coil domain containing 1 -1.77895
TPMT thiopurine S-methyltransferase -1.77293
MAPK14 mitogen-activated protein kinase 14 -1.77256
GSN gelsolin -1.76793
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) -1.76512
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa -1.75376
TGS1 trimethylguanosine synthase 1 -1.75071
ATF4 activating transcription factor 4 -1.74796
FURIN furin (paired basic amino acid cleaving enzyme) -1.74186
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 -1.73934
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 -1.73435
SRCAP Snf2-related CREBBP activator protein -1.73127
NOL9 nucleolar protein 9 -1.72696
BCL6 B-cell CLL/lymphoma 6 -1.72166
APMAP adipocyte plasma membrane associated protein -1.71448
USP16 ubiquitin specific peptidase 16 -1.71377
ZNF676 zinc finger protein 676 -1.71205
TCF20 transcription factor 20 (AR1) -1.7108
EDNRB endothelin receptor type B -1.70899
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) -1.70632
RPS3A ribosomal protein S3A -1.70377
CAB39 calcium binding protein 39 -1.70354
FZD4 frizzled class receptor 4 -1.70197
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa -1.69921
ACPP acid phosphatase, prostate -1.69849
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -1.69377
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -1.69374
SAV1 salvador family WW domain containing protein 1 -1.69308
C4ORF27 chromosome 4 open reading frame 27 -1.693
GTPBP3 GTP binding protein 3 (mitochondrial) -1.69139
CYB5R3 cytochrome b5 reductase 3 -1.68784
LMO2 LIM domain only 2 (rhombotin-like 1) -1.68753
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 -1.68439
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) -1.67964
MRPS14 mitochondrial ribosomal protein S14 -1.67939
S100B S100 calcium binding protein B -1.67825
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) -1.67679
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -1.67329
ZNF232 zinc finger protein 232 -1.66967
GYG2 glycogenin 2 -1.66854
RBX1 ring-box 1, E3 ubiquitin protein ligase -1.66831
CEPT1 choline/ethanolamine phosphotransferase 1 -1.66596
EPOR erythropoietin receptor -1.66562
HEBP2 heme binding protein 2 -1.66303
UQCRB ubiquinol-cytochrome c reductase binding protein -1.66289
PSKH1 protein serine kinase H1 -1.66275
ERN1 endoplasmic reticulum to nucleus signaling 1 -1.6626
CARD14 caspase recruitment domain family, member 14 -1.66072
KIF5C kinesin family member 5C -1.65991
PCF11 PCF11 cleavage and polyadenylation factor subunit -1.65831
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -1.65704
SPTBN5 spectrin, beta, non-erythrocytic 5 -1.65619
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 -1.65599
TMEM135 transmembrane protein 135 -1.65072
LINC00663 long intergenic non-protein coding RNA 663 -1.64987
ADIPOR2 adiponectin receptor 2 -1.64862
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -1.64669
HBA1 hemoglobin, alpha 1 -1.64586
NYX nyctalopin -1.64121
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -1.63985
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 -1.63212
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 -1.63003
MRPS22 mitochondrial ribosomal protein S22 -1.62884
JMJD6 jumonji domain containing 6 -1.62598
STX12 syntaxin 12 -1.62025
TTC19 tetratricopeptide repeat domain 19 -1.61931
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -1.61871
TALDO1 transaldolase 1 -1.61669
ZNF606 zinc finger protein 606 -1.61593
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -1.61485
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -1.61372
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -1.61138
ZNF672 zinc finger protein 672 -1.60772
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -1.60712
GTDC1 glycosyltransferase-like domain containing 1 -1.60703
MARVELD2 MARVEL domain containing 2 -1.60441
PAPD7 PAP associated domain containing 7 -1.60429
C9ORF78 chromosome 9 open reading frame 78 -1.60331
NGLY1 N-glycanase 1 -1.59857
ITGB1BP1 integrin beta 1 binding protein 1 -1.59811
SH2B3 SH2B adaptor protein 3 -1.59806
MKL2 MKL/myocardin-like 2 -1.59752
LAPTM4A lysosomal protein transmembrane 4 alpha -1.59687
EPHB4 EPH receptor B4 -1.59658
RPS20 ribosomal protein S20 -1.59582
BCL2 B-cell CLL/lymphoma 2 -1.59483
STOM stomatin -1.59023
SEC14L1 SEC14-like 1 (S. cerevisiae) -1.58983
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -1.58954
COQ10B coenzyme Q10 homolog B (S. cerevisiae) -1.58472
PANK4 pantothenate kinase 4 -1.58443
APOL3 apolipoprotein L, 3 -1.5799
TMEM62 transmembrane protein 62 -1.5782
FAM53C family with sequence similarity 53, member C -1.57507
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -1.57363
UIMC1 ubiquitin interaction motif containing 1 -1.57301
ASF1A anti-silencing function 1A histone chaperone -1.57089
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -1.56918
CRADD CASP2 and RIPK1 domain containing adaptor with death domain -1.56836
HBA2 hemoglobin, alpha 2 -1.56715
RPL30 ribosomal protein L30 -1.56694
MINA MYC induced nuclear antigen -1.56547
NIPBL Nipped-B homolog (Drosophila) -1.55966
ZNF35 zinc finger protein 35 -1.55878
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -1.55359
CERK ceramide kinase -1.55181
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) -1.54941
COPS4 COP9 signalosome subunit 4 -1.54866
TBC1D12 TBC1 domain family, member 12 -1.54654
BCL2L2 BCL2-like 2 -1.54609
CES2 carboxylesterase 2 -1.54454
ANKRD17 ankyrin repeat domain 17 -1.54395
ZHX3 zinc fingers and homeoboxes 3 -1.54295
CRYZL1 crystallin, zeta (quinone reductase)-like 1 -1.54215
FLT1 fms-related tyrosine kinase 1 -1.54066
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -1.53514
GCLC glutamate-cysteine ligase, catalytic subunit -1.5349
C14ORF169 chromosome 14 open reading frame 169 -1.53391
C9ORF91 chromosome 9 open reading frame 91 -1.5279
HPGDS hematopoietic prostaglandin D synthase -1.52779
ERP44 endoplasmic reticulum protein 44 -1.52574
AGA aspartylglucosaminidase -1.5235
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -1.5232
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -1.51867
GPR35 G protein-coupled receptor 35 -1.51579
CDC42SE1 CDC42 small effector 1 -1.51572
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -1.51479
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) -1.51459
KIAA0232 KIAA0232 -1.51075
REV1 REV1, polymerase (DNA directed) -1.5099
NFU1 NFU1 iron-sulfur cluster scaffold -1.50906
AKR1C2 aldo-keto reductase family 1, member C2 -1.50493
HBBP1 hemoglobin, beta pseudogene 1 -1.50416
ACAT1 acetyl-CoA acetyltransferase 1 -1.50373
EIF3E eukaryotic translation initiation factor 3, subunit E -1.50232
ZNF45 zinc finger protein 45 -1.5001
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 -1.49893
N4BP3 NEDD4 binding protein 3 -1.49891
ARRB1 arrestin, beta 1 -1.49663
MPRIP myosin phosphatase Rho interacting protein -1.4934
GNG4 guanine nucleotide binding protein (G protein), gamma 4 -1.49179
RNF139 ring finger protein 139 -1.48851
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -1.48829
DOLPP1 dolichyldiphosphatase 1 -1.48361
KANK2 KN motif and ankyrin repeat domains 2 -1.4817
ZNF79 zinc finger protein 79 -1.48038
SLC35B1 solute carrier family 35, member B1 -1.47841
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -1.47802
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -1.47762
NEU3 sialidase 3 (membrane sialidase) -1.47643
PPARG peroxisome proliferator-activated receptor gamma -1.47441
GGT1 gamma-glutamyltransferase 1 -1.46684
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -1.46089
CTSG cathepsin G -1.46044
TPCN1 two pore segment channel 1 -1.46009
PRDX4 peroxiredoxin 4 -1.45894
LPL lipoprotein lipase -1.45776
PDIA5 protein disulfide isomerase family A, member 5 -1.45773
TTTY1 testis-specific transcript, Y-linked 1 (non-protein coding) -1.4573
SERTAD4 SERTA domain containing 4 -1.45542
RPL36A ribosomal protein L36a -1.45537
LHFP lipoma HMGIC fusion partner -1.45518
TINAGL1 tubulointerstitial nephritis antigen-like 1 -1.45492
MRPS2 mitochondrial ribosomal protein S2 -1.45346
COPS5 COP9 signalosome subunit 5 -1.45303
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -1.45196
ADCY6 adenylate cyclase 6 -1.45167
C7ORF25 chromosome 7 open reading frame 25 -1.45153
CPA3 carboxypeptidase A3 (mast cell) -1.45086
RPL5 ribosomal protein L5 -1.45073
RBM22 RNA binding motif protein 22 -1.45034
ZNF75D zinc finger protein 75D -1.44905
PLEKHO2 pleckstrin homology domain containing, family O member 2 -1.44659
CDK19 cyclin-dependent kinase 19 -1.44443
VDAC1 voltage-dependent anion channel 1 -1.44415
ADD1 adducin 1 (alpha) -1.44234
LSM1 LSM1, U6 small nuclear RNA associated -1.44101
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B -1.44088
C1ORF54 chromosome 1 open reading frame 54 -1.4404
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) -1.43971
CASP9 caspase 9, apoptosis-related cysteine peptidase -1.4391
TACC2 transforming, acidic coiled-coil containing protein 2 -1.43784
OR2C1 olfactory receptor, family 2, subfamily C, member 1 -1.43714
USP5 ubiquitin specific peptidase 5 (isopeptidase T) -1.4368
TMEM97 transmembrane protein 97 -1.43348
SOX1 SRY (sex determining region Y)-box 1 -1.43155
CUTC cutC copper transporter -1.42973
REST RE1-silencing transcription factor -1.42859
RXRG retinoid X receptor, gamma -1.42714
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -1.42713
TROVE2 TROVE domain family, member 2 -1.42593
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -1.42486
RFTN1 raftlin, lipid raft linker 1 -1.42355
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) -1.42282
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -1.42209
MFN2 mitofusin 2 -1.42201
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -1.4197
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -1.41268
IFFO2 intermediate filament family orphan 2 -1.41254
CPT1A carnitine palmitoyltransferase 1A (liver) -1.4116
GFOD2 glucose-fructose oxidoreductase domain containing 2 -1.40982
EP400 E1A binding protein p400 -1.40874
PCOLCE2 procollagen C-endopeptidase enhancer 2 -1.40191
GOT2P1 glutamic-oxaloacetic transaminase 2 pseudogene 1 -1.40045
MYO5C myosin VC -1.40024
LARP7 La ribonucleoprotein domain family, member 7 -1.40003
REEP5 receptor accessory protein 5 -1.3986
TSPAN8 tetraspanin 8 -1.39699
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 -1.39494
YLPM1 YLP motif containing 1 -1.39407
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -1.39353
OXSM 3-oxoacyl-ACP synthase, mitochondrial -1.39049
CALM1 calmodulin 1 (phosphorylase kinase, delta) -1.39046
CDK6 cyclin-dependent kinase 6 -1.38882
JAK1 Janus kinase 1 -1.38736
NECAB3 N-terminal EF-hand calcium binding protein 3 -1.38611
XYLB xylulokinase homolog (H. influenzae) -1.38404
ARG2 arginase 2 -1.38292
CEP104 centrosomal protein 104kDa -1.38136
ROM1 retinal outer segment membrane protein 1 -1.38129