Major depressive disorder Gene Set

Dataset GWAS Catalog SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An endogenous depression that is characterized by an all-encompassing low mood accompanied by low self-esteem, and by loss of interest or pleasure in normally enjoyable activities. (Human Disease Ontology, DOID_1470)
External Link https://www.ebi.ac.uk/gwas/search?query=Major depressive disorder
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Genes

24 genes associated with the Major depressive disorder phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
MYO10 myosin X 0.405958
LOC643542 uncharacterized LOC643542 0.314454
ITGA11 integrin, alpha 11 0.295129
ENOX1 ecto-NOX disulfide-thiol exchanger 1 0.280662
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 0.246511
IL12A-AS1 IL12A antisense RNA 1 0.220915
PCLO piccolo presynaptic cytomatrix protein 0.220915
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.220915
LOC101927998 uncharacterized LOC101927998 0.220915
GMPR guanosine monophosphate reductase 0.220915
SHC4 SHC (Src homology 2 domain containing) family, member 4 0.165905
CCBE1 collagen and calcium binding EGF domains 1 0.129504
PIEZO2 piezo-type mechanosensitive ion channel component 2 0.129504
DMRT1 doublesex and mab-3 related transcription factor 1 0.104568
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5 0.104568
ZCCHC14 zinc finger, CCHC domain containing 14 0.085234
DVL3 dishevelled segment polarity protein 3 0.085234
SP4 Sp4 transcription factor 0.070053
PARP15 poly (ADP-ribose) polymerase family, member 15 0.070053
ATXN7L2 ataxin 7-like 2 0.070053
OFCC1 orofacial cleft 1 candidate 1 0.070053
AK8 adenylate kinase 8 0.048624
TRPS1 trichorhinophalangeal syndrome I 0.048624
ESRRG estrogen-related receptor gamma 0.042592