MS (Multiple Sclerosis)_CNS - Spinal Cord (MMHCC)_GSE842 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE842
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Genes

600 genes differentially expressed during MS (Multiple Sclerosis)_CNS - Spinal Cord (MMHCC)_GSE842 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
GLTP glycolipid transfer protein 4.22305
CCL3L3 chemokine (C-C motif) ligand 3-like 3 4.16983
PPIB peptidylprolyl isomerase B (cyclophilin B) 4.11732
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 4.11712
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 3.90319
EPN1 epsin 1 3.65851
FRMD8 FERM domain containing 8 3.61477
LAPTM5 lysosomal protein transmembrane 5 3.59535
EMB embigin 3.5586
RNPEP arginyl aminopeptidase (aminopeptidase B) 3.51582
CBX2 chromobox homolog 2 3.5037
RPLP0 ribosomal protein, large, P0 3.42164
MRPS18A mitochondrial ribosomal protein S18A 3.41064
RASAL3 RAS protein activator like 3 3.37197
RALGDS ral guanine nucleotide dissociation stimulator 3.32968
GOLM1 golgi membrane protein 1 3.27788
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 3.13588
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 3.12257
CXXC1 CXXC finger protein 1 3.11269
ENG endoglin 3.10107
TLE3 transducin-like enhancer of split 3 3.09388
TMED9 transmembrane emp24 protein transport domain containing 9 3.0773
PGLS 6-phosphogluconolactonase 3.07702
ZFP36L2 ZFP36 ring finger protein-like 2 3.06068
IL10RB interleukin 10 receptor, beta 3.00855
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 2.98812
CSF1 colony stimulating factor 1 (macrophage) 2.94717
C1QC complement component 1, q subcomponent, C chain 2.91782
OR4E2 olfactory receptor, family 4, subfamily E, member 2 2.89865
LYN LYN proto-oncogene, Src family tyrosine kinase 2.88345
SLC35E1 solute carrier family 35, member E1 2.86792
LYPD8 LY6/PLAUR domain containing 8 2.86717
S100A4 S100 calcium binding protein A4 2.8326
IL17RA interleukin 17 receptor A 2.79334
SRSF6 serine/arginine-rich splicing factor 6 2.78417
CDAN1 codanin 1 2.76679
CSK c-src tyrosine kinase 2.76061
FOSL2 FOS-like antigen 2 2.75836
TMEM141 transmembrane protein 141 2.72368
LCN2 lipocalin 2 2.72346
P4HB prolyl 4-hydroxylase, beta polypeptide 2.70888
TLN1 talin 1 2.68333
RAX retina and anterior neural fold homeobox 2.67989
GPX3 glutathione peroxidase 3 2.64078
RBM17 RNA binding motif protein 17 2.61245
CH25H cholesterol 25-hydroxylase 2.61176
UPP1 uridine phosphorylase 1 2.60717
NR1I3 nuclear receptor subfamily 1, group I, member 3 2.58084
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 2.55209
EBI3 Epstein-Barr virus induced 3 2.55197
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 2.54767
GAS7 growth arrest-specific 7 2.54608
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 2.54095
TPM3 tropomyosin 3 2.53587
IRF8 interferon regulatory factor 8 2.51706
COL4A1 collagen, type IV, alpha 1 2.49794
SAA1 serum amyloid A1 2.49542
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.48843
GALR2 galanin receptor 2 2.46685
C1QB complement component 1, q subcomponent, B chain 2.46347
CIAPIN1 cytokine induced apoptosis inhibitor 1 2.45151
C1QA complement component 1, q subcomponent, A chain 2.45013
TSPO translocator protein (18kDa) 2.44455
LGALS9B lectin, galactoside-binding, soluble, 9B 2.43648
IFT27 intraflagellar transport 27 2.38767
PTPN6 protein tyrosine phosphatase, non-receptor type 6 2.37285
CORO1A coronin, actin binding protein, 1A 2.35399
CPNE1 copine I 2.34851
ATAD2B ATPase family, AAA domain containing 2B 2.34127
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 2.33829
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) 2.32811
KRT35 keratin 35, type I 2.32294
LTF lactotransferrin 2.32142
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.30766
RPL19 ribosomal protein L19 2.3061
IFT88 intraflagellar transport 88 2.29716
MSH2 mutS homolog 2 2.28537
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 2.27188
PID1 phosphotyrosine interaction domain containing 1 2.27093
KLF3 Kruppel-like factor 3 (basic) 2.25929
CLEC3B C-type lectin domain family 3, member B 2.25164
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 2.25084
AMPD3 adenosine monophosphate deaminase 3 2.24089
LAMB1 laminin, beta 1 2.23078
LCK LCK proto-oncogene, Src family tyrosine kinase 2.23032
BARX1 BARX homeobox 1 2.22279
LY86 lymphocyte antigen 86 2.21544
FCF1 FCF1 rRNA-processing protein 2.21165
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 2.21033
ANXA3 annexin A3 2.20583
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.20442
SLC31A1 solute carrier family 31 (copper transporter), member 1 2.19926
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 2.19285
CREB3L1 cAMP responsive element binding protein 3-like 1 2.16805
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.16728
LCOR ligand dependent nuclear receptor corepressor 2.16432
MYO1C myosin IC 2.16194
ACO1 aconitase 1, soluble 2.14632
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 2.13374
SEPT9 septin 9 2.13363
NEK2 NIMA-related kinase 2 2.12979
MEIS2 Meis homeobox 2 2.12903
HDAC7 histone deacetylase 7 2.12779
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 2.12571
BIRC5 baculoviral IAP repeat containing 5 2.1074
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 2.10609
FCGBP Fc fragment of IgG binding protein 2.10101
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.09863
TNXB tenascin XB 2.09485
RALB v-ral simian leukemia viral oncogene homolog B 2.0939
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 2.08827
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 2.08792
NR1H4 nuclear receptor subfamily 1, group H, member 4 2.0834
MRPL16 mitochondrial ribosomal protein L16 2.07353
PRRX2 paired related homeobox 2 2.07042
GNG12 guanine nucleotide binding protein (G protein), gamma 12 2.07037
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 2.06895
COL4A2 collagen, type IV, alpha 2 2.06512
MYOZ1 myozenin 1 2.05877
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 2.058
S100A8 S100 calcium binding protein A8 2.05247
GTPBP1 GTP binding protein 1 2.04253
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 2.03852
THAP7 THAP domain containing 7 2.03804
BAZ1B bromodomain adjacent to zinc finger domain, 1B 2.03622
CTSV cathepsin V 2.03428
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 2.02608
GADD45G growth arrest and DNA-damage-inducible, gamma 2.02171
C9ORF3 chromosome 9 open reading frame 3 2.02119
FN1 fibronectin 1 2.01045
ANKRD13A ankyrin repeat domain 13A 2.00538
RP1L1 retinitis pigmentosa 1-like 1 2.00265
PRPF31 pre-mRNA processing factor 31 2.0011
HAUS8 HAUS augmin-like complex, subunit 8 1.99787
TIAM1 T-cell lymphoma invasion and metastasis 1 1.98179
CCNL2 cyclin L2 1.97972
PTPRM protein tyrosine phosphatase, receptor type, M 1.97656
YARS tyrosyl-tRNA synthetase 1.97285
CCR4 chemokine (C-C motif) receptor 4 1.96983
CER1 cerberus 1, DAN family BMP antagonist 1.96916
SPATA13 spermatogenesis associated 13 1.96023
C3ORF38 chromosome 3 open reading frame 38 1.95719
SRSF7 serine/arginine-rich splicing factor 7 1.95012
APRT adenine phosphoribosyltransferase 1.94979
AHNAK AHNAK nucleoprotein 1.94248
PRL prolactin 1.93678
COL12A1 collagen, type XII, alpha 1 1.93586
ACVRL1 activin A receptor type II-like 1 1.93527
PNPLA2 patatin-like phospholipase domain containing 2 1.93078
ERP29 endoplasmic reticulum protein 29 1.92854
NAGA N-acetylgalactosaminidase, alpha- 1.92585
TMOD3 tropomodulin 3 (ubiquitous) 1.92582
UMPS uridine monophosphate synthetase 1.92001
RRAS related RAS viral (r-ras) oncogene homolog 1.90909
RAP2B RAP2B, member of RAS oncogene family 1.90905
DPYSL2 dihydropyrimidinase-like 2 1.90437
PPP4C protein phosphatase 4, catalytic subunit 1.90388
GNS glucosamine (N-acetyl)-6-sulfatase 1.89675
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 1.88757
ADGRG3 adhesion G protein-coupled receptor G3 1.87336
JMJD6 jumonji domain containing 6 1.87309
ACRC acidic repeat containing 1.87263
PABPC1 poly(A) binding protein, cytoplasmic 1 1.8702
MAD2L1BP MAD2L1 binding protein 1.86821
TWSG1 twisted gastrulation BMP signaling modulator 1 1.86768
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 1.86644
HTT huntingtin 1.8588
GPI glucose-6-phosphate isomerase 1.85785
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 1.8565
CLU clusterin 1.85495
FAM20C family with sequence similarity 20, member C 1.85308
S100A10 S100 calcium binding protein A10 1.85183
GPN2 GPN-loop GTPase 2 1.84302
DTX1 deltex 1, E3 ubiquitin ligase 1.83967
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 1.83963
FBL fibrillarin 1.83905
HOXA11 homeobox A11 1.83007
BHLHE40 basic helix-loop-helix family, member e40 1.829
METTL8 methyltransferase like 8 1.82392
MBD3 methyl-CpG binding domain protein 3 1.8212
GJA5 gap junction protein, alpha 5, 40kDa 1.819
PHF23 PHD finger protein 23 1.81467
IRF9 interferon regulatory factor 9 1.81355
LAMA5 laminin, alpha 5 1.80907
UCK2 uridine-cytidine kinase 2 1.80405
SHISA5 shisa family member 5 1.80374
IGFBP6 insulin-like growth factor binding protein 6 1.80315
FLOT1 flotillin 1 1.80017
UBQLN4 ubiquilin 4 1.79962
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) 1.79752
CCRL2 chemokine (C-C motif) receptor-like 2 1.79286
ISG20 interferon stimulated exonuclease gene 20kDa 1.79268
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.79023
GDAP2 ganglioside induced differentiation associated protein 2 1.7893
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 1.78373
MOB1A MOB kinase activator 1A 1.77472
WDR43 WD repeat domain 43 1.77382
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 1.77233
TPST2 tyrosylprotein sulfotransferase 2 1.77074
TACSTD2 tumor-associated calcium signal transducer 2 1.7687
ZFR2 zinc finger RNA binding protein 2 1.76481
TSKS testis-specific serine kinase substrate 1.7634
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 1.76326
CKAP5 cytoskeleton associated protein 5 1.76303
GADD45A growth arrest and DNA-damage-inducible, alpha 1.76097
GRN granulin 1.75777
SYPL2 synaptophysin-like 2 1.75682
FTH1 ferritin, heavy polypeptide 1 1.75353
CYB5R4 cytochrome b5 reductase 4 1.75293
NFIL3 nuclear factor, interleukin 3 regulated 1.74915
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.7473
CLIC3 chloride intracellular channel 3 1.74323
S100A6 S100 calcium binding protein A6 1.74176
PXN paxillin 1.73977
XPO6 exportin 6 1.73654
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 1.73485
HCRT hypocretin (orexin) neuropeptide precursor 1.73346
SYNGR1 synaptogyrin 1 1.72686
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 1.72675
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 1.72456
FXYD1 FXYD domain containing ion transport regulator 1 1.72164
C16ORF70 chromosome 16 open reading frame 70 1.71382
IKBIP IKBKB interacting protein 1.71342
TINAGL1 tubulointerstitial nephritis antigen-like 1 1.7105
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 1.70897
TLR6 toll-like receptor 6 1.70734
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.70006
PRKD2 protein kinase D2 1.69807
NHP2 NHP2 ribonucleoprotein 1.69637
TADA2B transcriptional adaptor 2B 1.69554
TAGLN2 transgelin 2 1.69208
PRRC2A proline-rich coiled-coil 2A 1.69124
SCX scleraxis basic helix-loop-helix transcription factor 1.68992
FAM195B family with sequence similarity 195, member B 1.68202
C3 complement component 3 1.68088
CCL2 chemokine (C-C motif) ligand 2 1.68042
TBRG4 transforming growth factor beta regulator 4 1.67223
ARHGAP9 Rho GTPase activating protein 9 1.67194
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.66569
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 1.65942
PFKL phosphofructokinase, liver 1.65941
MYO1F myosin IF 1.65556
LAT linker for activation of T cells 1.65334
CYBA cytochrome b-245, alpha polypeptide 1.65259
SOX13 SRY (sex determining region Y)-box 13 1.64897
BAX BCL2-associated X protein 1.64843
ACTN4 actinin, alpha 4 1.64793
SARNP SAP domain containing ribonucleoprotein 1.6463
SBF2 SET binding factor 2 1.64617
LDHA lactate dehydrogenase A 1.64594
JAK3 Janus kinase 3 1.64049
CD37 CD37 molecule 1.63287
GABARAP GABA(A) receptor-associated protein 1.63089
IRF5 interferon regulatory factor 5 1.62852
CTSH cathepsin H 1.62418
CNN3 calponin 3, acidic 1.62148
NFYA nuclear transcription factor Y, alpha 1.62028
NUP85 nucleoporin 85kDa 1.62007
WDR81 WD repeat domain 81 1.61937
ACY1 aminoacylase 1 1.61862
ATG4B autophagy related 4B, cysteine peptidase 1.6169
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 1.61589
HOXB6 homeobox B6 1.61497
OGFR opioid growth factor receptor 1.61417
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1.61074
METAP1 methionyl aminopeptidase 1 1.60467
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21 1.60261
GNG10 guanine nucleotide binding protein (G protein), gamma 10 1.60141
HIST1H3C histone cluster 1, H3c 1.60013
PNPT1 polyribonucleotide nucleotidyltransferase 1 1.59918
GIF gastric intrinsic factor (vitamin B synthesis) 1.59872
SAT1 spermidine/spermine N1-acetyltransferase 1 1.59747
IKZF4 IKAROS family zinc finger 4 (Eos) 1.59727
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 1.59647
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 1.59293
NUBP1 nucleotide binding protein 1 1.59003
SAP30L SAP30-like 1.58746
TGS1 trimethylguanosine synthase 1 1.58664
LAMC2 laminin, gamma 2 1.57934
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 1.57666
NT5DC3 5'-nucleotidase domain containing 3 1.57659
PROS1 protein S (alpha) 1.57581
FES FES proto-oncogene, tyrosine kinase 1.57569
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) 1.57521
CD9 CD9 molecule 1.57431
GFPT2 glutamine-fructose-6-phosphate transaminase 2 1.57186
SFTPC surfactant protein C 1.57099
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 1.56628
KLF6 Kruppel-like factor 6 1.56473
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) 1.56187
SUSD6 sushi domain containing 6 1.56121
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 1.56058
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 1.5552
PSEN2 presenilin 2 1.55038
PPP6R3 protein phosphatase 6, regulatory subunit 3 1.54273
LGALS1 lectin, galactoside-binding, soluble, 1 1.5424
IQGAP3 IQ motif containing GTPase activating protein 3 1.53539
HBS1L HBS1-like translational GTPase 1.53444
SSTR1 somatostatin receptor 1 1.53249
CD14 CD14 molecule 1.52275

decreased expression

Symbol Name Standardized Value
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant -3.48788
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 -2.75515
AUH AU RNA binding protein/enoyl-CoA hydratase -2.7512
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 -2.6663
AMH anti-Mullerian hormone -2.6486
CX3CL1 chemokine (C-X3-C motif) ligand 1 -2.62317
DHODH dihydroorotate dehydrogenase (quinone) -2.57858
ZNF22 zinc finger protein 22 -2.53193
STX1B syntaxin 1B -2.33081
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -2.31849
TMEM169 transmembrane protein 169 -2.22981
PSTK phosphoseryl-tRNA kinase -2.15228
CDC25A cell division cycle 25A -2.11071
CCNDBP1 cyclin D-type binding-protein 1 -2.04521
MECOM MDS1 and EVI1 complex locus -2.0446
NR1D2 nuclear receptor subfamily 1, group D, member 2 -2.01009
KIF5C kinesin family member 5C -1.99266
GATA4 GATA binding protein 4 -1.94576
FOXO4 forkhead box O4 -1.91884
RUVBL1 RuvB-like AAA ATPase 1 -1.91462
GAMT guanidinoacetate N-methyltransferase -1.90184
CA5A carbonic anhydrase VA, mitochondrial -1.88847
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 -1.87642
NGRN neugrin, neurite outgrowth associated -1.8732
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -1.86808
DEPTOR DEP domain containing MTOR-interacting protein -1.84201
GSTP1 glutathione S-transferase pi 1 -1.82229
AIP aryl hydrocarbon receptor interacting protein -1.79553
ADGRE5 adhesion G protein-coupled receptor E5 -1.77596
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 -1.77047
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -1.75459
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -1.75113
MYH10 myosin, heavy chain 10, non-muscle -1.7437
BOK BCL2-related ovarian killer -1.73586
FNBP1 formin binding protein 1 -1.72175
CYHR1 cysteine/histidine-rich 1 -1.71192
UTF1 undifferentiated embryonic cell transcription factor 1 -1.71024
KRTAP3-1 keratin associated protein 3-1 -1.70369
MAPK9 mitogen-activated protein kinase 9 -1.7011
SLC22A23 solute carrier family 22, member 23 -1.69549
GFM1 G elongation factor, mitochondrial 1 -1.68364
TXLNG taxilin gamma -1.68176
SBNO1 strawberry notch homolog 1 (Drosophila) -1.67028
USP22 ubiquitin specific peptidase 22 -1.65865
MKNK1 MAP kinase interacting serine/threonine kinase 1 -1.65785
LAMC1 laminin, gamma 1 (formerly LAMB2) -1.62866
GCDH glutaryl-CoA dehydrogenase -1.6286
BTBD3 BTB (POZ) domain containing 3 -1.60364
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa -1.58949
METTL7A methyltransferase like 7A -1.56563
EPN2 epsin 2 -1.55077
GSN gelsolin -1.54293
BDKRB1 bradykinin receptor B1 -1.52503
C14ORF1 chromosome 14 open reading frame 1 -1.5113
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -1.51112
HOXD8 homeobox D8 -1.50905
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae) -1.50359
ACTL6B actin-like 6B -1.50087
SPHK2 sphingosine kinase 2 -1.48152
ZNF32 zinc finger protein 32 -1.48149
GTF2I general transcription factor IIi -1.47807
AXIN2 axin 2 -1.47788
RAP1GAP RAP1 GTPase activating protein -1.47472
ATG5 autophagy related 5 -1.45843
SUV420H2 suppressor of variegation 4-20 homolog 2 (Drosophila) -1.45815
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) -1.45291
HSPA4L heat shock 70kDa protein 4-like -1.4526
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide -1.44895
HPN hepsin -1.43644
BLK BLK proto-oncogene, Src family tyrosine kinase -1.43509
SFXN2 sideroflexin 2 -1.43294
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 -1.42391
SMYD1 SET and MYND domain containing 1 -1.40757
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -1.39954
SEPT6 septin 6 -1.39775
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) -1.39572
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled -1.3951
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 -1.37407
GSTM5 glutathione S-transferase mu 5 -1.37203
FAM110A family with sequence similarity 110, member A -1.37159
APC2 adenomatosis polyposis coli 2 -1.3691
UBTD2 ubiquitin domain containing 2 -1.36766
MYH14 myosin, heavy chain 14, non-muscle -1.34747
PDE8A phosphodiesterase 8A -1.34696
PEBP1 phosphatidylethanolamine binding protein 1 -1.34672
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -1.34429
CPLX1 complexin 1 -1.34336
INO80E INO80 complex subunit E -1.33281
NSF N-ethylmaleimide-sensitive factor -1.33208
CACNB2 calcium channel, voltage-dependent, beta 2 subunit -1.32871
TAT tyrosine aminotransferase -1.29538
SULT4A1 sulfotransferase family 4A, member 1 -1.28548
MMP17 matrix metallopeptidase 17 (membrane-inserted) -1.28357
CCKAR cholecystokinin A receptor -1.2816
BSN bassoon presynaptic cytomatrix protein -1.27904
ATP13A2 ATPase type 13A2 -1.27497
CENPA centromere protein A -1.27189
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 -1.27021
SLC22A17 solute carrier family 22, member 17 -1.26744
GSTK1 glutathione S-transferase kappa 1 -1.26567
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -1.26538
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 -1.26469
LY6H lymphocyte antigen 6 complex, locus H -1.25984
PCGF2 polycomb group ring finger 2 -1.25132
IL18R1 interleukin 18 receptor 1 -1.24639
FHDC1 FH2 domain containing 1 -1.24396
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -1.24193
GRB10 growth factor receptor-bound protein 10 -1.23594
TRAPPC2L trafficking protein particle complex 2-like -1.23579
ARL2 ADP-ribosylation factor-like 2 -1.23392
SYT11 synaptotagmin XI -1.2253
PHGDH phosphoglycerate dehydrogenase -1.22193
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) -1.21271
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 -1.19799
OCIAD1 OCIA domain containing 1 -1.19449
RIMKLB ribosomal modification protein rimK-like family member B -1.19432
UNC13B unc-13 homolog B (C. elegans) -1.19009
F2R coagulation factor II (thrombin) receptor -1.18566
PRF1 perforin 1 (pore forming protein) -1.18264
PDK3 pyruvate dehydrogenase kinase, isozyme 3 -1.18057
BBS9 Bardet-Biedl syndrome 9 -1.16676
MRPL38 mitochondrial ribosomal protein L38 -1.16539
RPP14 ribonuclease P/MRP 14kDa subunit -1.16501
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) -1.15805
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta -1.15538
NMU neuromedin U -1.1548
ELP5 elongator acetyltransferase complex subunit 5 -1.15237
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha -1.14286
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -1.14239
GAB1 GRB2-associated binding protein 1 -1.13809
LIMK1 LIM domain kinase 1 -1.13665
EVI5 ecotropic viral integration site 5 -1.1224
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -1.11036
HES1 hes family bHLH transcription factor 1 -1.10812
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -1.10428
ZXDB zinc finger, X-linked, duplicated B -1.10234
EYA2 EYA transcriptional coactivator and phosphatase 2 -1.10185
FABP2 fatty acid binding protein 2, intestinal -1.10018
MTX2 metaxin 2 -1.09973
ATXN10 ataxin 10 -1.09873
RRP1B ribosomal RNA processing 1B -1.0915
PCBP4 poly(rC) binding protein 4 -1.0912
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25 -1.08774
DQX1 DEAQ box RNA-dependent ATPase 1 -1.0874
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -1.08731
HDAC5 histone deacetylase 5 -1.0873
PHF5A PHD finger protein 5A -1.0775
AZGP1 alpha-2-glycoprotein 1, zinc-binding -1.07615
ITGB4 integrin, beta 4 -1.07374
ZFP92 ZFP92 zinc finger protein -1.07337
PSMG3 proteasome (prosome, macropain) assembly chaperone 3 -1.07333
FOXF1 forkhead box F1 -1.07055
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 -1.06166
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide -1.06143
NDN necdin, melanoma antigen (MAGE) family member -1.06123
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19 -1.05953
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 -1.05527
MRPL42 mitochondrial ribosomal protein L42 -1.0521
ZBTB17 zinc finger and BTB domain containing 17 -1.04975
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 -1.04853
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 -1.04359
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -1.04226
SAMD10 sterile alpha motif domain containing 10 -1.04075
ZNF561 zinc finger protein 561 -1.03801
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -1.03727
DPPA2 developmental pluripotency associated 2 -1.03587
SEPT4 septin 4 -1.03472
RRM1 ribonucleotide reductase M1 -1.03466
ELP3 elongator acetyltransferase complex subunit 3 -1.03152
EVI2A ecotropic viral integration site 2A -1.02266
ATXN7L3B ataxin 7-like 3B -1.02249
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 -1.01693
TMEM59 transmembrane protein 59 -1.01585
EXOC7 exocyst complex component 7 -1.01372
CPNE6 copine VI (neuronal) -1.01356
MATN4 matrilin 4 -1.01307
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -1.01195
LYSMD2 LysM, putative peptidoglycan-binding, domain containing 2 -1.0103
ATOH7 atonal homolog 7 (Drosophila) -1.00944
CLDND1 claudin domain containing 1 -1.00755
CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6 -1.00688
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa -1.00652
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -1.00629
TCTE1 t-complex-associated-testis-expressed 1 -1.00561
UPK2 uroplakin 2 -1.00128
CAND1 cullin-associated and neddylation-dissociated 1 -0.997778
TBX2 T-box 2 -0.995524
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.995097
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.994278
SMO smoothened, frizzled class receptor -0.993474
C1GALT1C1 C1GALT1-specific chaperone 1 -0.992557
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -0.990215
NKAIN1 Na+/K+ transporting ATPase interacting 1 -0.988544
NECAP1 NECAP endocytosis associated 1 -0.983341
PLP1 proteolipid protein 1 -0.981998
MED28 mediator complex subunit 28 -0.981603
C14ORF2 chromosome 14 open reading frame 2 -0.977392
TRPC5 transient receptor potential cation channel, subfamily C, member 5 -0.974202
GSX1 GS homeobox 1 -0.973317
ZBTB20 zinc finger and BTB domain containing 20 -0.972531
TUBB tubulin, beta class I -0.972164
MOG myelin oligodendrocyte glycoprotein -0.971099
TESK1 testis-specific kinase 1 -0.966888
NIT2 nitrilase family, member 2 -0.966648
PPARD peroxisome proliferator-activated receptor delta -0.963742
POLR1C polymerase (RNA) I polypeptide C, 30kDa -0.962071
AP2A1 adaptor-related protein complex 2, alpha 1 subunit -0.959692
ANKRD10 ankyrin repeat domain 10 -0.959632
ZNF503 zinc finger protein 503 -0.956835
LSG1 large 60S subunit nuclear export GTPase 1 -0.956205
ZNF143 zinc finger protein 143 -0.956139
ENSA endosulfine alpha -0.955301
PRPF6 pre-mRNA processing factor 6 -0.954631
SYPL1 synaptophysin-like 1 -0.948737
EPHA2 EPH receptor A2 -0.941891
KCNS2 potassium voltage-gated channel, modifier subfamily S, member 2 -0.939094
PLA2R1 phospholipase A2 receptor 1, 180kDa -0.934147
REG1A regenerating islet-derived 1 alpha -0.932687
ADAM23 ADAM metallopeptidase domain 23 -0.931246
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 -0.929394
KDM3A lysine (K)-specific demethylase 3A -0.928851
PDCD6IP programmed cell death 6 interacting protein -0.928438
GUCY2C guanylate cyclase 2C -0.928184
GPR27 G protein-coupled receptor 27 -0.927415
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -0.923594
LPAR1 lysophosphatidic acid receptor 1 -0.923474
ATRX alpha thalassemia/mental retardation syndrome X-linked -0.918086
NDRG3 NDRG family member 3 -0.917713
HOXA5 homeobox A5 -0.917108
SNAP47 synaptosomal-associated protein, 47kDa -0.910134
HOXD9 homeobox D9 -0.907061
PCP4 Purkinje cell protein 4 -0.906788
SYN2 synapsin II -0.903418
FOXRED1 FAD-dependent oxidoreductase domain containing 1 -0.902703
PLTP phospholipid transfer protein -0.900881
MTSS1L metastasis suppressor 1-like -0.898978
THAP4 THAP domain containing 4 -0.897714
CDK8 cyclin-dependent kinase 8 -0.893919
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 -0.893753
GPC3 glypican 3 -0.890911
PROSC proline synthetase co-transcribed homolog (bacterial) -0.890822
BAIAP2 BAI1-associated protein 2 -0.889645
H2AFJ H2A histone family, member J -0.889233
ANKRD46 ankyrin repeat domain 46 -0.887907
CECR5 cat eye syndrome chromosome region, candidate 5 -0.887236
PIGS phosphatidylinositol glycan anchor biosynthesis, class S -0.884654
ANAPC13 anaphase promoting complex subunit 13 -0.884228
FH fumarate hydratase -0.883005
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.882329
UTS2R urotensin 2 receptor -0.881056
GALC galactosylceramidase -0.879878
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -0.877534
ZNF444 zinc finger protein 444 -0.875882
RBM10 RNA binding motif protein 10 -0.875458
CASP9 caspase 9, apoptosis-related cysteine peptidase -0.874924
EDF1 endothelial differentiation-related factor 1 -0.871729
RFK riboflavin kinase -0.869973
BAG2 BCL2-associated athanogene 2 -0.869609
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -0.869405
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) -0.868594
CDK5 cyclin-dependent kinase 5 -0.867194
GALR3 galanin receptor 3 -0.865992
LMF1 lipase maturation factor 1 -0.8656
EFS embryonal Fyn-associated substrate -0.864904
SMAD6 SMAD family member 6 -0.863787
TFF3 trefoil factor 3 (intestinal) -0.862415
FAM69B family with sequence similarity 69, member B -0.861001
CD8B CD8b molecule -0.860741
MID1IP1 MID1 interacting protein 1 -0.859802
ULK1 unc-51 like autophagy activating kinase 1 -0.858288
TSPAN12 tetraspanin 12 -0.857386
CA2 carbonic anhydrase II -0.855834
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 -0.851247
EGLN2 egl-9 family hypoxia-inducible factor 2 -0.849512
CYTH1 cytohesin 1 -0.847403
ARNTL aryl hydrocarbon receptor nuclear translocator-like -0.847069
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.842596
REL v-rel avian reticuloendotheliosis viral oncogene homolog -0.840122
ASTN1 astrotactin 1 -0.83997
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.838661
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 -0.838135
IL5 interleukin 5 -0.837515
SIRT2 sirtuin 2 -0.835143
MRPL35 mitochondrial ribosomal protein L35 -0.834118
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.832365
MPHOSPH9 M-phase phosphoprotein 9 -0.826939
TUBG2 tubulin, gamma 2 -0.824712
RNF13 ring finger protein 13 -0.824692
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.824616
OCLN occludin -0.823321
UNC45A unc-45 homolog A (C. elegans) -0.819103
MTM1 myotubularin 1 -0.819013
UGT8 UDP glycosyltransferase 8 -0.816095
SIAH2 siah E3 ubiquitin protein ligase 2 -0.815207
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.813743
ACPP acid phosphatase, prostate -0.813152
RNF167 ring finger protein 167 -0.810748
FGF1 fibroblast growth factor 1 (acidic) -0.810652
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) -0.809006
WDR5 WD repeat domain 5 -0.807738