MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE2779 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2779
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Genes

600 genes differentially expressed during MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE2779 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 3.30543
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 3.05851
ADAR adenosine deaminase, RNA-specific 2.81547
ANKRD49 ankyrin repeat domain 49 2.74156
C2ORF47 chromosome 2 open reading frame 47 2.50606
ST7 suppression of tumorigenicity 7 2.49747
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 2.48347
COPS7A COP9 signalosome subunit 7A 2.42928
CORO1C coronin, actin binding protein, 1C 2.42575
EXT2 exostosin glycosyltransferase 2 2.39903
FASTKD5 FAST kinase domains 5 2.38329
UBE2A ubiquitin-conjugating enzyme E2A 2.36126
MAD2L1BP MAD2L1 binding protein 2.3507
TARS threonyl-tRNA synthetase 2.25946
TUBGCP4 tubulin, gamma complex associated protein 4 2.25754
MOB1A MOB kinase activator 1A 2.24226
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 2.23237
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 2.22543
ATF4 activating transcription factor 4 2.22498
MIA3 melanoma inhibitory activity family, member 3 2.19134
TUBA1C tubulin, alpha 1c 2.18143
POLR1C polymerase (RNA) I polypeptide C, 30kDa 2.16338
RBMX RNA binding motif protein, X-linked 2.15843
DSTN destrin (actin depolymerizing factor) 2.15301
MRPS35 mitochondrial ribosomal protein S35 2.15246
MAN2A2 mannosidase, alpha, class 2A, member 2 2.12211
DNPEP aspartyl aminopeptidase 2.1144
COPS2 COP9 signalosome subunit 2 2.10052
SNX3 sorting nexin 3 2.09823
RPN2 ribophorin II 2.07848
CLP1 cleavage and polyadenylation factor I subunit 1 2.06437
SOCS5 suppressor of cytokine signaling 5 2.06233
CHMP1A charged multivesicular body protein 1A 2.0534
SEPT7 septin 7 2.03551
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 2.02553
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.02464
C20ORF24 chromosome 20 open reading frame 24 2.00322
USP48 ubiquitin specific peptidase 48 1.9915
SLC35B1 solute carrier family 35, member B1 1.97613
LOC100129361 1.96901
FAM175B family with sequence similarity 175, member B 1.96791
GANAB glucosidase, alpha; neutral AB 1.96639
ISCA1 iron-sulfur cluster assembly 1 1.94864
EI24 etoposide induced 2.4 1.9465
ESYT1 extended synaptotagmin-like protein 1 1.94608
C5ORF22 chromosome 5 open reading frame 22 1.9436
TMEM9B TMEM9 domain family, member B 1.9352
ROPN1B rhophilin associated tail protein 1B 1.92534
CDC5L cell division cycle 5-like 1.92198
CMC2 C-x(9)-C motif containing 2 1.91981
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 1.91582
KAT7 K(lysine) acetyltransferase 7 1.9124
MARS methionyl-tRNA synthetase 1.91169
COPS8 COP9 signalosome subunit 8 1.90935
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 1.90575
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 1.90002
SUMO3 small ubiquitin-like modifier 3 1.89811
GORASP2 golgi reassembly stacking protein 2, 55kDa 1.89269
C10ORF88 chromosome 10 open reading frame 88 1.89149
ZNF468 zinc finger protein 468 1.87606
STAT1 signal transducer and activator of transcription 1, 91kDa 1.87361
SRCAP Snf2-related CREBBP activator protein 1.86537
GRWD1 glutamate-rich WD repeat containing 1 1.86225
DUT deoxyuridine triphosphatase 1.85918
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 1.85877
LSM1 LSM1, U6 small nuclear RNA associated 1.85309
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 1.85189
RCL1 RNA terminal phosphate cyclase-like 1 1.85062
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 1.84419
SQLE squalene epoxidase 1.8423
RFC3 replication factor C (activator 1) 3, 38kDa 1.84176
BZW1 basic leucine zipper and W2 domains 1 1.83796
ZNF134 zinc finger protein 134 1.82777
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal 1.82441
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.81597
PNN pinin, desmosome associated protein 1.78916
FAM162A family with sequence similarity 162, member A 1.78395
PTP4A2 protein tyrosine phosphatase type IVA, member 2 1.78134
SUMO4 small ubiquitin-like modifier 4 1.77951
SSB Sjogren syndrome antigen B (autoantigen La) 1.77487
GOLGA7 golgin A7 1.77419
TMEM164 transmembrane protein 164 1.77099
CHMP3 charged multivesicular body protein 3 1.76556
RNF10 ring finger protein 10 1.76455
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 1.76027
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa 1.75845
RNF187 ring finger protein 187 1.75832
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2 1.75794
ZNF443 zinc finger protein 443 1.75724
EIF5 eukaryotic translation initiation factor 5 1.75401
SEC31A SEC31 homolog A (S. cerevisiae) 1.74485
GSPT1 G1 to S phase transition 1 1.74411
TRIM13 tripartite motif containing 13 1.74377
ASNSD1 asparagine synthetase domain containing 1 1.7435
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) 1.7359
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 1.73317
ELF4 E74-like factor 4 (ets domain transcription factor) 1.72007
UBE2D3 ubiquitin-conjugating enzyme E2D 3 1.7171
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 1.71634
PGAM1 phosphoglycerate mutase 1 (brain) 1.70442
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 1.69783
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 1.69569
IDE insulin-degrading enzyme 1.69344
OPTN optineurin 1.69296
LAMP2 lysosomal-associated membrane protein 2 1.69038
ARF3 ADP-ribosylation factor 3 1.68782
PTGES3 prostaglandin E synthase 3 (cytosolic) 1.68295
ENDOD1 endonuclease domain containing 1 1.67514
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.67442
METTL22 methyltransferase like 22 1.67073
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 1.66959
UROD uroporphyrinogen decarboxylase 1.66876
HYOU1 hypoxia up-regulated 1 1.66854
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 1.6656
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.6603
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 1.65711
PTPRO protein tyrosine phosphatase, receptor type, O 1.6561
TCP10L t-complex 10-like 1.65356
YES1 YES proto-oncogene 1, Src family tyrosine kinase 1.64855
PITPNB phosphatidylinositol transfer protein, beta 1.63947
RANBP6 RAN binding protein 6 1.63697
TMCO1 transmembrane and coiled-coil domains 1 1.63278
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 1.63208
TSPAN31 tetraspanin 31 1.62801
PABPC1 poly(A) binding protein, cytoplasmic 1 1.62647
OSBPL9 oxysterol binding protein-like 9 1.62048
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 1.61985
GSTK1 glutathione S-transferase kappa 1 1.6176
ACAT2 acetyl-CoA acetyltransferase 2 1.61208
BAG5 BCL2-associated athanogene 5 1.60909
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 1.60846
RNF139 ring finger protein 139 1.60813
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) 1.60201
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 1.59977
RUSC1 RUN and SH3 domain containing 1 1.59914
PNRC2 proline-rich nuclear receptor coactivator 2 1.59884
ZNF552 zinc finger protein 552 1.59869
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 1.59808
VTI1B vesicle transport through interaction with t-SNAREs 1B 1.59505
RBM8A RNA binding motif protein 8A 1.59288
GMCL1 germ cell-less, spermatogenesis associated 1 1.59127
DUSP12 dual specificity phosphatase 12 1.59111
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 1.58849
EMC3 ER membrane protein complex subunit 3 1.58849
HOMER2 homer scaffolding protein 2 1.58654
CYCS cytochrome c, somatic 1.58573
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 1.58381
LRRC8B leucine rich repeat containing 8 family, member B 1.57716
XKR8 XK, Kell blood group complex subunit-related family, member 8 1.57689
RNF114 ring finger protein 114 1.57521
ITM2A integral membrane protein 2A 1.57166
FBXO7 F-box protein 7 1.57124
SLC25A46 solute carrier family 25, member 46 1.57009
ACTR5 ARP5 actin-related protein 5 homolog (yeast) 1.56805
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.55918
BZW2 basic leucine zipper and W2 domains 2 1.55768
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 1.55458
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 1.55374
CRTC1 CREB regulated transcription coactivator 1 1.55272
SEC14L5 SEC14-like 5 (S. cerevisiae) 1.55094
ZNF14 zinc finger protein 14 1.54478
ATXN10 ataxin 10 1.54469
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 1.54066
C1ORF95 chromosome 1 open reading frame 95 1.53811
SETD6 SET domain containing 6 1.5377
NXPE3 neurexophilin and PC-esterase domain family, member 3 1.53596
PROSER1 proline and serine rich 1 1.53556
WIPF1 WAS/WASL interacting protein family, member 1 1.53535
RWDD3 RWD domain containing 3 1.53358
UBAP1 ubiquitin associated protein 1 1.52596
PAIP1 poly(A) binding protein interacting protein 1 1.52334
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 1.52052
MORF4L2 mortality factor 4 like 2 1.51975
CMC4 C-x(9)-C motif containing 4 1.51698
PCDHGB5 protocadherin gamma subfamily B, 5 1.51334
DESI2 desumoylating isopeptidase 2 1.51301
LGALS8 lectin, galactoside-binding, soluble, 8 1.50894
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 1.50782
EIF4A3 eukaryotic translation initiation factor 4A3 1.50643
KIF2A kinesin heavy chain member 2A 1.50566
RBM39 RNA binding motif protein 39 1.50244
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 1.50158
EIF1B eukaryotic translation initiation factor 1B 1.50069
ABHD4 abhydrolase domain containing 4 1.4992
APMAP adipocyte plasma membrane associated protein 1.49035
GTF2A2 general transcription factor IIA, 2, 12kDa 1.49018
ACSL3 acyl-CoA synthetase long-chain family member 3 1.48869
TFAM transcription factor A, mitochondrial 1.48852
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 1.48519
FAS Fas cell surface death receptor 1.48271
CREG1 cellular repressor of E1A-stimulated genes 1 1.47884
RAB3B RAB3B, member RAS oncogene family 1.4762
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 1.47593
PTPRH protein tyrosine phosphatase, receptor type, H 1.46748
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 1.46586
PEX19 peroxisomal biogenesis factor 19 1.46518
ATF2 activating transcription factor 2 1.46454
MUC8 mucin 8 1.46373
MAPK6 mitogen-activated protein kinase 6 1.46232
CHUK conserved helix-loop-helix ubiquitous kinase 1.45557
RNASEH1 ribonuclease H1 1.45091
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 1.45031
FAM8A1 family with sequence similarity 8, member A1 1.45007
RPS13 ribosomal protein S13 1.44647
UBE2E1 ubiquitin-conjugating enzyme E2E 1 1.44578
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 1.44525
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 1.44403
EFS embryonal Fyn-associated substrate 1.43996
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 1.43964
GBP2 guanylate binding protein 2, interferon-inducible 1.43931
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 1.43896
GTPBP8 GTP-binding protein 8 (putative) 1.4368
RFK riboflavin kinase 1.43622
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 1.43529
TCEAL4 transcription elongation factor A (SII)-like 4 1.43453
RAP2C RAP2C, member of RAS oncogene family 1.43376
RPL23A ribosomal protein L23a 1.43141
TBR1 T-box, brain, 1 1.42973
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 1.42889
SH3BGRL SH3 domain binding glutamate-rich protein like 1.42841
YME1L1 YME1-like 1 ATPase 1.42681
VAMP3 vesicle-associated membrane protein 3 1.4217
EGR4 early growth response 4 1.42052
CCBL2 cysteine conjugate-beta lyase 2 1.4197
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 1.41811
TBC1D13 TBC1 domain family, member 13 1.41716
NET1 neuroepithelial cell transforming 1 1.41422
TMPRSS3 transmembrane protease, serine 3 1.41398
CDV3 CDV3 homolog (mouse) 1.41197
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 1.41177
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 1.40893
COMMD9 COMM domain containing 9 1.40808
PARN poly(A)-specific ribonuclease 1.40632
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.40495
DDIT3 DNA-damage-inducible transcript 3 1.40493
PSORS1C1 psoriasis susceptibility 1 candidate 1 1.40463
C1ORF50 chromosome 1 open reading frame 50 1.40387
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 1.40244
CGRRF1 cell growth regulator with ring finger domain 1 1.40222
ZCCHC2 zinc finger, CCHC domain containing 2 1.40161
MEST mesoderm specific transcript 1.40047
RAB22A RAB22A, member RAS oncogene family 1.39908
ATG3 autophagy related 3 1.39895
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 1.39892
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) 1.39839
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.39529
UBE2N ubiquitin-conjugating enzyme E2N 1.39401
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.39283
FKBP14 FK506 binding protein 14, 22 kDa 1.39182
CANX calnexin 1.39073
PNPO pyridoxamine 5'-phosphate oxidase 1.39046
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 1.38996
ZBTB5 zinc finger and BTB domain containing 5 1.38768
GYPB glycophorin B (MNS blood group) 1.38717
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 1.38696
MAN2B2 mannosidase, alpha, class 2B, member 2 1.38469
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 1.38385
ECD ecdysoneless homolog (Drosophila) 1.38196
ZBTB39 zinc finger and BTB domain containing 39 1.38183
TRIM21 tripartite motif containing 21 1.3817
TNIP2 TNFAIP3 interacting protein 2 1.38091
WBP1L WW domain binding protein 1-like 1.38058
PCNP PEST proteolytic signal containing nuclear protein 1.38039
HMGN3 high mobility group nucleosomal binding domain 3 1.37954
H2AFV H2A histone family, member V 1.37724
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 1.37576
ADAMDEC1 ADAM-like, decysin 1 1.37533
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 1.3743
GPR157 G protein-coupled receptor 157 1.37356
FASLG Fas ligand (TNF superfamily, member 6) 1.37352
MUL1 mitochondrial E3 ubiquitin protein ligase 1 1.36713
UBE2E3 ubiquitin-conjugating enzyme E2E 3 1.3671
ITM2B integral membrane protein 2B 1.36699
DNAAF5 dynein, axonemal, assembly factor 5 1.36515
KCNK5 potassium channel, two pore domain subfamily K, member 5 1.3632
SMNDC1 survival motor neuron domain containing 1 1.36208
CNOT7 CCR4-NOT transcription complex, subunit 7 1.36122
API5 apoptosis inhibitor 5 1.35951
TBL2 transducin (beta)-like 2 1.35904
RIC8A RIC8 guanine nucleotide exchange factor A 1.35849
LPAR1 lysophosphatidic acid receptor 1 1.35826
NOL6 nucleolar protein 6 (RNA-associated) 1.35422
NAGA N-acetylgalactosaminidase, alpha- 1.35282
GAPT GRB2-binding adaptor protein, transmembrane 1.35184
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 1.35145
ARMCX6 armadillo repeat containing, X-linked 6 1.35125
TMEM184C transmembrane protein 184C 1.35003
TMEM45A transmembrane protein 45A 1.34947
LPAR3 lysophosphatidic acid receptor 3 1.34815
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 1.34753
SNX11 sorting nexin 11 1.34574
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 1.34564
GAS8 growth arrest-specific 8 1.34531
RNF11 ring finger protein 11 1.34498
DYNLL1 dynein, light chain, LC8-type 1 1.34375
DUSP3 dual specificity phosphatase 3 1.34069
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 1.34029
MRPS10 mitochondrial ribosomal protein S10 1.34028
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 1.33826
YAF2 YY1 associated factor 2 1.33801

decreased expression

Symbol Name Standardized Value
SEPHS1 selenophosphate synthetase 1 -2.88369
PHF10 PHD finger protein 10 -2.79416
LRMP lymphoid-restricted membrane protein -2.77587
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.65311
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 -2.56602
ZNF365 zinc finger protein 365 -2.5152
CHMP1B charged multivesicular body protein 1B -2.49474
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -2.46687
KIF13A kinesin family member 13A -2.46341
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 -2.42873
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -2.39864
FYCO1 FYVE and coiled-coil domain containing 1 -2.39625
COL3A1 collagen, type III, alpha 1 -2.39542
DPP8 dipeptidyl-peptidase 8 -2.36349
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 -2.35152
ADCY9 adenylate cyclase 9 -2.33154
TSPAN14 tetraspanin 14 -2.32536
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -2.31871
MYO1B myosin IB -2.31103
PHKB phosphorylase kinase, beta -2.31096
EPHB2 EPH receptor B2 -2.30345
ZC3H4 zinc finger CCCH-type containing 4 -2.26191
MCF2L MCF.2 cell line derived transforming sequence-like -2.26097
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -2.24634
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -2.23938
POU4F1 POU class 4 homeobox 1 -2.2229
WDR59 WD repeat domain 59 -2.20532
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -2.20369
TWIST1 twist family bHLH transcription factor 1 -2.19116
ITGA10 integrin, alpha 10 -2.18464
TRIP4 thyroid hormone receptor interactor 4 -2.1821
MARK3 MAP/microtubule affinity-regulating kinase 3 -2.18136
DHODH dihydroorotate dehydrogenase (quinone) -2.18083
HPS4 Hermansky-Pudlak syndrome 4 -2.18007
SEC63 SEC63 homolog (S. cerevisiae) -2.16851
KIAA0355 KIAA0355 -2.15256
ARHGAP17 Rho GTPase activating protein 17 -2.15168
RPL5 ribosomal protein L5 -2.14498
PARP1 poly (ADP-ribose) polymerase 1 -2.13291
TMBIM4 transmembrane BAX inhibitor motif containing 4 -2.1304
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) -2.11889
TJP1 tight junction protein 1 -2.11251
ATG2B autophagy related 2B -2.10509
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -2.08707
DESI1 desumoylating isopeptidase 1 -2.0841
SESN1 sestrin 1 -2.08263
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -2.08126
FAM111A family with sequence similarity 111, member A -2.07842
HIST1H2AB histone cluster 1, H2ab -2.0631
CDK13 cyclin-dependent kinase 13 -2.06017
CTBP2 C-terminal binding protein 2 -2.05746
MTUS1 microtubule associated tumor suppressor 1 -2.05651
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) -2.04981
SETDB1 SET domain, bifurcated 1 -2.0352
CCNH cyclin H -2.03493
BTN2A2 butyrophilin, subfamily 2, member A2 -2.032
UBXN1 UBX domain protein 1 -2.02323
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) -2.01677
EFNB3 ephrin-B3 -2.00938
ITPKC inositol-trisphosphate 3-kinase C -1.99147
GSTA4 glutathione S-transferase alpha 4 -1.98782
LINC00341 long intergenic non-protein coding RNA 341 -1.98324
C22ORF24 chromosome 22 open reading frame 24 -1.98169
ZNF133 zinc finger protein 133 -1.98106
RREB1 ras responsive element binding protein 1 -1.95932
MID1IP1 MID1 interacting protein 1 -1.94907
ZNF672 zinc finger protein 672 -1.94101
NUDCD3 NudC domain containing 3 -1.93983
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 -1.93965
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -1.93902
ZNF7 zinc finger protein 7 -1.92789
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) -1.90952
KRIT1 KRIT1, ankyrin repeat containing -1.89787
FBXO9 F-box protein 9 -1.8975
FAM107A family with sequence similarity 107, member A -1.89434
KDM4C lysine (K)-specific demethylase 4C -1.89278
YPEL1 yippee-like 1 (Drosophila) -1.88508
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) -1.88295
RGS5 regulator of G-protein signaling 5 -1.87071
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -1.86897
NIPBL Nipped-B homolog (Drosophila) -1.86779
ETFDH electron-transferring-flavoprotein dehydrogenase -1.86297
TCF3 transcription factor 3 -1.85941
CALM1 calmodulin 1 (phosphorylase kinase, delta) -1.85064
LARP4B La ribonucleoprotein domain family, member 4B -1.84989
FAM178A family with sequence similarity 178, member A -1.84664
CA12 carbonic anhydrase XII -1.84448
ARID5B AT rich interactive domain 5B (MRF1-like) -1.83536
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -1.82398
RPS4X ribosomal protein S4, X-linked -1.82241
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -1.82204
ADAM17 ADAM metallopeptidase domain 17 -1.8209
SRR serine racemase -1.81694
SND1 staphylococcal nuclease and tudor domain containing 1 -1.81254
MDN1 MDN1, midasin homolog (yeast) -1.8024
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -1.80219
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 -1.80203
SRSF7 serine/arginine-rich splicing factor 7 -1.79561
TRIM45 tripartite motif containing 45 -1.79462
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 -1.79115
INSL3 insulin-like 3 (Leydig cell) -1.78426
R3HDM2 R3H domain containing 2 -1.78402
SYT11 synaptotagmin XI -1.78327
DRAM1 DNA-damage regulated autophagy modulator 1 -1.77245
GIPC3 GIPC PDZ domain containing family, member 3 -1.76267
TSG101 tumor susceptibility 101 -1.75915
BSPRY B-box and SPRY domain containing -1.75884
PXDN peroxidasin -1.75636
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -1.75603
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 -1.75241
RABGAP1 RAB GTPase activating protein 1 -1.7521
NEIL3 nei endonuclease VIII-like 3 (E. coli) -1.75159
CASP4 caspase 4, apoptosis-related cysteine peptidase -1.75082
KIF22 kinesin family member 22 -1.74799
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2 -1.74753
ULK2 unc-51 like autophagy activating kinase 2 -1.74641
ANAPC1 anaphase promoting complex subunit 1 -1.74372
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -1.73954
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene -1.73941
MELK maternal embryonic leucine zipper kinase -1.73899
FHIT fragile histidine triad -1.73588
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 -1.73529
R3HDM1 R3H domain containing 1 -1.73413
KIAA0226 KIAA0226 -1.73155
NOL7 nucleolar protein 7, 27kDa -1.72648
LDAH lipid droplet associated hydrolase -1.72489
NAIP NLR family, apoptosis inhibitory protein -1.71972
ZNF544 zinc finger protein 544 -1.71758
FAIM2 Fas apoptotic inhibitory molecule 2 -1.71408
IQSEC1 IQ motif and Sec7 domain 1 -1.70701
TOP2B topoisomerase (DNA) II beta 180kDa -1.70399
FBXL14 F-box and leucine-rich repeat protein 14 -1.70135
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -1.70081
DCN decorin -1.70042
TTC17 tetratricopeptide repeat domain 17 -1.7
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) -1.7
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -1.69952
CEP68 centrosomal protein 68kDa -1.6952
CSNK2A2 casein kinase 2, alpha prime polypeptide -1.6951
BCL2L13 BCL2-like 13 (apoptosis facilitator) -1.6902
HNF4A hepatocyte nuclear factor 4, alpha -1.68979
AMPD3 adenosine monophosphate deaminase 3 -1.68958
DIO2 deiodinase, iodothyronine, type II -1.68772
ARHGAP19 Rho GTPase activating protein 19 -1.67957
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -1.67842
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 -1.67682
ZNF248 zinc finger protein 248 -1.67554
PBX3 pre-B-cell leukemia homeobox 3 -1.67398
FNTA farnesyltransferase, CAAX box, alpha -1.67377
ELAVL1 ELAV like RNA binding protein 1 -1.6734
UBE2Z ubiquitin-conjugating enzyme E2Z -1.67113
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 -1.66796
MTF2 metal response element binding transcription factor 2 -1.66361
BRCA1 breast cancer 1, early onset -1.66239
PIAS3 protein inhibitor of activated STAT, 3 -1.65935
CEP192 centrosomal protein 192kDa -1.65863
PDIA4 protein disulfide isomerase family A, member 4 -1.65706
ZNF692 zinc finger protein 692 -1.6564
NPC1 Niemann-Pick disease, type C1 -1.65495
PRPF3 pre-mRNA processing factor 3 -1.65467
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -1.64581
HMGB2 high mobility group box 2 -1.64495
NGDN neuroguidin, EIF4E binding protein -1.6448
POLB polymerase (DNA directed), beta -1.64077
BTBD3 BTB (POZ) domain containing 3 -1.64059
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial -1.63944
PCNX pecanex homolog (Drosophila) -1.63769
NME7 NME/NM23 family member 7 -1.63433
GEMIN8 gem (nuclear organelle) associated protein 8 -1.63174
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 -1.63165
AMBRA1 autophagy/beclin-1 regulator 1 -1.63163
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 -1.62605
CSNK1A1 casein kinase 1, alpha 1 -1.62257
SMAD2 SMAD family member 2 -1.62249
ADD3 adducin 3 (gamma) -1.61891
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) -1.61832
SYNE2 spectrin repeat containing, nuclear envelope 2 -1.61763
ZFHX2 zinc finger homeobox 2 -1.61739
CARD10 caspase recruitment domain family, member 10 -1.61245
IKZF1 IKAROS family zinc finger 1 (Ikaros) -1.60792
TBP TATA box binding protein -1.60752
SLC35E3 solute carrier family 35, member E3 -1.60652
TMCC1 transmembrane and coiled-coil domain family 1 -1.60251
CGGBP1 CGG triplet repeat binding protein 1 -1.60162
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa -1.59999
SRSF1 serine/arginine-rich splicing factor 1 -1.59992
NARF nuclear prelamin A recognition factor -1.59694
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -1.59478
PTEN phosphatase and tensin homolog -1.59204
KIFC1 kinesin family member C1 -1.59118
CALCOCO2 calcium binding and coiled-coil domain 2 -1.5899
TEX10 testis expressed 10 -1.58932
PCDH17 protocadherin 17 -1.5891
LIMK2 LIM domain kinase 2 -1.58738
WWTR1 WW domain containing transcription regulator 1 -1.58661
RIMS3 regulating synaptic membrane exocytosis 3 -1.58653
ACP2 acid phosphatase 2, lysosomal -1.58373
RFTN1 raftlin, lipid raft linker 1 -1.58308
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -1.58265
PSRC1 proline/serine-rich coiled-coil 1 -1.58173
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding) -1.57667
ACACB acetyl-CoA carboxylase beta -1.57581
FTO fat mass and obesity associated -1.57512
COG2 component of oligomeric golgi complex 2 -1.57368
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) -1.56946
TAPT1 transmembrane anterior posterior transformation 1 -1.56808
DET1 de-etiolated homolog 1 (Arabidopsis) -1.56709
WDR73 WD repeat domain 73 -1.56656
NUP88 nucleoporin 88kDa -1.56488
GOLGA1 golgin A1 -1.56352
PSPC1 paraspeckle component 1 -1.56321
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene -1.56191
MTMR4 myotubularin related protein 4 -1.56168
SKAP1 src kinase associated phosphoprotein 1 -1.55955
ENC1 ectodermal-neural cortex 1 (with BTB domain) -1.55625
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -1.55499
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -1.55408
OSBPL2 oxysterol binding protein-like 2 -1.55385
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 -1.55183
FNBP4 formin binding protein 4 -1.5518
APOLD1 apolipoprotein L domain containing 1 -1.55117
AHCYL2 adenosylhomocysteinase-like 2 -1.54335
ODC1 ornithine decarboxylase 1 -1.54316
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -1.54186
NCALD neurocalcin delta -1.54167
IFFO2 intermediate filament family orphan 2 -1.53912
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 -1.53564
PEX1 peroxisomal biogenesis factor 1 -1.53391
CADM1 cell adhesion molecule 1 -1.53332
FAM114A1 family with sequence similarity 114, member A1 -1.53146
CELF1 CUGBP, Elav-like family member 1 -1.52989
PRKDC protein kinase, DNA-activated, catalytic polypeptide -1.52841
GPSM2 G-protein signaling modulator 2 -1.52596
KIF3C kinesin family member 3C -1.52537
LAT2 linker for activation of T cells family, member 2 -1.52492
PRSS22 protease, serine, 22 -1.52479
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A -1.52397
MCAM melanoma cell adhesion molecule -1.52368
ADCY2 adenylate cyclase 2 (brain) -1.51936
TSPAN6 tetraspanin 6 -1.51857
SPTBN1 spectrin, beta, non-erythrocytic 1 -1.51759
LCMT2 leucine carboxyl methyltransferase 2 -1.5143
EP400 E1A binding protein p400 -1.51172
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 -1.51129
FAM64A family with sequence similarity 64, member A -1.51104
MAGED1 melanoma antigen family D1 -1.50711
ZNF536 zinc finger protein 536 -1.50403
ZNF451 zinc finger protein 451 -1.50285
PCDHGA9 protocadherin gamma subfamily A, 9 -1.50143
PCNT pericentrin -1.50076
KSR1 kinase suppressor of ras 1 -1.49795
KANK2 KN motif and ankyrin repeat domains 2 -1.49498
DDR1 discoidin domain receptor tyrosine kinase 1 -1.49203
BDH2 3-hydroxybutyrate dehydrogenase, type 2 -1.49144
NCAPD2 non-SMC condensin I complex, subunit D2 -1.49074
MYH14 myosin, heavy chain 14, non-muscle -1.48955
WDR70 WD repeat domain 70 -1.48896
TDP1 tyrosyl-DNA phosphodiesterase 1 -1.48825
BTG1 B-cell translocation gene 1, anti-proliferative -1.4875
REV1 REV1, polymerase (DNA directed) -1.4872
ZNRD1-AS1 ZNRD1 antisense RNA 1 -1.48633
GML glycosylphosphatidylinositol anchored molecule like -1.47868
OSBPL11 oxysterol binding protein-like 11 -1.47577
SYNRG synergin, gamma -1.47376
FBXL5 F-box and leucine-rich repeat protein 5 -1.47321
COL5A1 collagen, type V, alpha 1 -1.47096
RAG1 recombination activating gene 1 -1.47055
AGRN agrin -1.46927
TIMELESS timeless circadian clock -1.46815
IGF2R insulin-like growth factor 2 receptor -1.46783
TERF2 telomeric repeat binding factor 2 -1.46505
CRMP1 collapsin response mediator protein 1 -1.46423
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -1.45883
FAM208A family with sequence similarity 208, member A -1.45747
HSPD1 heat shock 60kDa protein 1 (chaperonin) -1.45731
PTPN9 protein tyrosine phosphatase, non-receptor type 9 -1.4567
PELI2 pellino E3 ubiquitin protein ligase family member 2 -1.45515
FAM53B family with sequence similarity 53, member B -1.45514
NGLY1 N-glycanase 1 -1.4519
HMGN2 high mobility group nucleosomal binding domain 2 -1.44856
C10ORF10 chromosome 10 open reading frame 10 -1.44802
NF2 neurofibromin 2 (merlin) -1.4479
CROT carnitine O-octanoyltransferase -1.4455
EIF1 eukaryotic translation initiation factor 1 -1.44315
MYB v-myb avian myeloblastosis viral oncogene homolog -1.44101
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -1.44076
RGS12 regulator of G-protein signaling 12 -1.43862
STK32B serine/threonine kinase 32B -1.43839
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -1.43473
KIF13B kinesin family member 13B -1.43454
JAM2 junctional adhesion molecule 2 -1.42936
AKAP1 A kinase (PRKA) anchor protein 1 -1.42933
GATAD1 GATA zinc finger domain containing 1 -1.42885
IVNS1ABP influenza virus NS1A binding protein -1.42813
AIM1 absent in melanoma 1 -1.42501
TEFM transcription elongation factor, mitochondrial -1.41984
VSIG10 V-set and immunoglobulin domain containing 10 -1.41967
CCL17 chemokine (C-C motif) ligand 17 -1.41925
MORF4L1 mortality factor 4 like 1 -1.41905
TFF3 trefoil factor 3 (intestinal) -1.41855