Lymphatic Diseases Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D008206
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Genes

353 genes/proteins associated with the disease Lymphatic Diseases from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
IL6 interleukin 6 1.96193
CAT catalase 1.85221
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.78378
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.73129
TP53 tumor protein p53 1.69951
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.69297
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.65249
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.65023
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.63698
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.59148
TNF tumor necrosis factor 1.58936
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.58208
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.5816
CXCL8 chemokine (C-X-C motif) ligand 8 1.56994
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.5528
ANGPTL4 angiopoietin-like 4 1.53357
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.52566
IL10 interleukin 10 1.52136
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.50979
BAX BCL2-associated X protein 1.50725
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.50273
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.49174
IGF1 insulin-like growth factor 1 (somatomedin C) 1.48813
DDIT3 DNA-damage-inducible transcript 3 1.4817
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.47296
BCL2 B-cell CLL/lymphoma 2 1.45989
CXCL2 chemokine (C-X-C motif) ligand 2 1.45326
VEGFA vascular endothelial growth factor A 1.44166
JUN jun proto-oncogene 1.44111
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.43591
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.43212
GSTP1 glutathione S-transferase pi 1 1.41396
NOS2 nitric oxide synthase 2, inducible 1.41063
IFNG interferon, gamma 1.40429
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.39869
POR P450 (cytochrome) oxidoreductase 1.39702
TGFB2 transforming growth factor, beta 2 1.39226
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.38891
MMP13 matrix metallopeptidase 13 1.38128
MMP9 matrix metallopeptidase 9 1.38015
F3 coagulation factor III (thromboplastin, tissue factor) 1.37987
CCL2 chemokine (C-C motif) ligand 2 1.37619
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.37475
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.37475
NQO1 NAD(P)H dehydrogenase, quinone 1 1.36876
ERN1 endoplasmic reticulum to nucleus signaling 1 1.36591
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.36076
FABP4 fatty acid binding protein 4, adipocyte 1.36047
MMP3 matrix metallopeptidase 3 1.35906
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.35357
FADS2 fatty acid desaturase 2 1.34372
IFITM3 interferon induced transmembrane protein 3 1.3414
AHR aryl hydrocarbon receptor 1.34111
IL1B interleukin 1, beta 1.34111
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.33731
NR1H3 nuclear receptor subfamily 1, group H, member 3 1.33081
CCND1 cyclin D1 1.32905
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.32667
HMGB1 high mobility group box 1 1.31686
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.30941
IL1R1 interleukin 1 receptor, type I 1.30512
S100A9 S100 calcium binding protein A9 1.29966
COL1A1 collagen, type I, alpha 1 1.29966
CLU clusterin 1.29564
XDH xanthine dehydrogenase 1.29564
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.29564
CIDEA cell death-inducing DFFA-like effector a 1.29256
GSTM1 glutathione S-transferase mu 1 1.28703
NFE2L2 nuclear factor, erythroid 2-like 2 1.27997
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.27751
BBC3 BCL2 binding component 3 1.27626
TLR2 toll-like receptor 2 1.26763
ECI1 enoyl-CoA delta isomerase 1 1.26545
CKM creatine kinase, muscle 1.25713
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.25463
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.25432
PPARG peroxisome proliferator-activated receptor gamma 1.254
CCL3 chemokine (C-C motif) ligand 3 1.25369
LCAT lecithin-cholesterol acyltransferase 1.25152
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.24874
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.24843
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.24718
CDK2 cyclin-dependent kinase 2 1.24244
EFNA1 ephrin-A1 1.23868
ANXA4 annexin A4 1.23616
WEE1 WEE1 G2 checkpoint kinase 1.23616
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.23201
CHEK1 checkpoint kinase 1 1.23042
NPAS2 neuronal PAS domain protein 2 1.22979
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 1.22979
TF transferrin 1.22306
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.2208
IGF1R insulin-like growth factor 1 receptor 1.22016
GSR glutathione reductase 1.21951
CDK1 cyclin-dependent kinase 1 1.21887
CCL5 chemokine (C-C motif) ligand 5 1.21823
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.21663
ENDOD1 endonuclease domain containing 1 1.21534
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.21435
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.21337
HMOX1 heme oxygenase 1 1.21271
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.21173
HADH hydroxyacyl-CoA dehydrogenase 1.21173
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 1.21076
SOD2 superoxide dismutase 2, mitochondrial 1.21043
DBT dihydrolipoamide branched chain transacylase E2 1.20622
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.2059
PPP1R3B protein phosphatase 1, regulatory subunit 3B 1.20163
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.20064
TSPO translocator protein (18kDa) 1.19379
LIMA1 LIM domain and actin binding 1 1.19345
IGFBP3 insulin-like growth factor binding protein 3 1.19146
PRKD3 protein kinase D3 1.18915
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 1.18554
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase 1.18521
CAPSL calcyphosine-like 1.18489
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 1.18326
ORM1 orosomucoid 1 1.18159
APOA4 apolipoprotein A-IV 1.18126
POLA2 polymerase (DNA directed), alpha 2, accessory subunit 1.17695
GYS2 glycogen synthase 2 (liver) 1.17695
SDS serine dehydratase 1.17695
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.17695
ZEB2 zinc finger E-box binding homeobox 2 1.17333
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.17268
OR2L13 olfactory receptor, family 2, subfamily L, member 13 1.17235
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.17134
ICAM1 intercellular adhesion molecule 1 1.17101
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.16933
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.16933
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 1.16933
CRIP2 cysteine-rich protein 2 1.16933
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.16933
HLA-B major histocompatibility complex, class I, B 1.166
DCT dopachrome tautomerase 1.16567
EIF1 eukaryotic translation initiation factor 1 1.16567
CD36 CD36 molecule (thrombospondin receptor) 1.16533
INSR insulin receptor 1.16533
IDI1 isopentenyl-diphosphate delta isomerase 1 1.16335
APOA1 apolipoprotein A-I 1.16302
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 1.16236
ENPEP glutamyl aminopeptidase (aminopeptidase A) 1.16203
DBN1 drebrin 1 1.16203
G6PD glucose-6-phosphate dehydrogenase 1.16203
SORBS1 sorbin and SH3 domain containing 1 1.16203
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 1.16203
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.16137
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.15933
RRAS2 related RAS viral (r-ras) oncogene homolog 2 1.15831
PC pyruvate carboxylase 1.15831
FKBP5 FK506 binding protein 5 1.15763
RNF2 ring finger protein 2 1.15661
ASPA aspartoacylase 1.15492
SHMT1 serine hydroxymethyltransferase 1 (soluble) 1.15458
PGRMC1 progesterone receptor membrane component 1 1.15458
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.15189
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 1.15189
HRAS Harvey rat sarcoma viral oncogene homolog 1.15022
SQLE squalene epoxidase 1.14989
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 1.14816
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 1.14747
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.14644
G6PC glucose-6-phosphatase, catalytic subunit 1.14438
EGR1 early growth response 1 1.14336
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.14234
PHEX phosphate regulating endopeptidase homolog, X-linked 1.14166
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.14132
PPARD peroxisome proliferator-activated receptor delta 1.14064
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.13963
IL1A interleukin 1, alpha 1.13895
SOX17 SRY (sex determining region Y)-box 17 1.13793
AK2 adenylate kinase 2 1.13758
IL2 interleukin 2 1.13586
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.13484
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.13381
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.13211
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.13041
LPL lipoprotein lipase 1.13041
HSPB1 heat shock 27kDa protein 1 1.1294
GSTA1 glutathione S-transferase alpha 1 1.1294
GLUL glutamate-ammonia ligase 1.12872
TGFB1 transforming growth factor, beta 1 1.12805
CKAP2 cytoskeleton associated protein 2 1.12771
TMEM97 transmembrane protein 97 1.12771
RAD51 RAD51 recombinase 1.12703
S100A8 S100 calcium binding protein A8 1.12703
STMN1 stathmin 1 1.12703
CA14 carbonic anhydrase XIV 1.12461
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 1.12461
NADK2 NAD kinase 2, mitochondrial 1.12426
GPX2 glutathione peroxidase 2 1.12357
ANXA2 annexin A2 1.12185
CDT1 chromatin licensing and DNA replication factor 1 1.11877
SUSD4 sushi domain containing 4 1.11707
ACADL acyl-CoA dehydrogenase, long chain 1.11571
APOB apolipoprotein B 1.11536
EBP emopamil binding protein (sterol isomerase) 1.11536
GADD45B growth arrest and DNA-damage-inducible, beta 1.11396
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.11255
MVP major vault protein 1.11255
GSTA2 glutathione S-transferase alpha 2 1.11081
ACSL1 acyl-CoA synthetase long-chain family member 1 1.11046
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 1.11011
ARSG arylsulfatase G 1.10977
MAPK3 mitogen-activated protein kinase 3 1.10942
GCLM glutamate-cysteine ligase, modifier subunit 1.10665
RELN reelin 1.10665
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.10596
TXNIP thioredoxin interacting protein 1.10562
TXNRD1 thioredoxin reductase 1 1.10562
MFAP5 microfibrillar associated protein 5 1.10353
S1PR5 sphingosine-1-phosphate receptor 5 1.10317
IL4 interleukin 4 1.10282
ATF3 activating transcription factor 3 1.09857
CSF1R colony stimulating factor 1 receptor 1.09822
INSIG1 insulin induced gene 1 1.09786
ACHE acetylcholinesterase (Yt blood group) 1.09681
BEX4 brain expressed, X-linked 4 1.09646
ADIPOR2 adiponectin receptor 2 1.09576
NDRG1 N-myc downstream regulated 1 1.0919
PHTF1 putative homeodomain transcription factor 1 1.09083
FAM65B family with sequence similarity 65, member B 1.09011
TMEM47 transmembrane protein 47 1.09011
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 1.09011
DUT deoxyuridine triphosphatase 1.08975
MAPK8 mitogen-activated protein kinase 8 1.08868
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.08726
VCL vinculin 1.0869
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.08584
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.08584
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 1.08442
CXCR4 chemokine (C-X-C motif) receptor 4 1.08442
TGIF1 TGFB-induced factor homeobox 1 1.08442
ENO1 enolase 1, (alpha) 1.08301
ACSL3 acyl-CoA synthetase long-chain family member 3 1.08231
NT5E 5'-nucleotidase, ecto (CD73) 1.08196
MCM7 minichromosome maintenance complex component 7 1.08196
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 1.08161
E2F1 E2F transcription factor 1 1.08161
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.08019
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase 1.07911
CTSB cathepsin B 1.07875
IGFBP1 insulin-like growth factor binding protein 1 1.07875
TTC39A tetratricopeptide repeat domain 39A 1.0784
GSTM3 glutathione S-transferase mu 3 (brain) 1.07732
LEPR leptin receptor 1.07696
ATF4 activating transcription factor 4 1.07589
CFD complement factor D (adipsin) 1.07411
EIF5 eukaryotic translation initiation factor 5 1.07411
ESR1 estrogen receptor 1 1.07376
MRPL19 mitochondrial ribosomal protein L19 1.07305
MAMDC2 MAM domain containing 2 1.07199
CCNF cyclin F 1.07163
F10 coagulation factor X 1.07163
TKT transketolase 1.06917
GSK3B glycogen synthase kinase 3 beta 1.06808
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.06734
DCAF11 DDB1 and CUL4 associated factor 11 1.06734
ICK intestinal cell (MAK-like) kinase 1.06698
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 1.06661
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.06625
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.06588
STIP1 stress-induced phosphoprotein 1 1.06442
LIPC lipase, hepatic 1.06442
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.06406
DIO1 deiodinase, iodothyronine, type I 1.06188
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 1.06188
SQSTM1 sequestosome 1 1.06188
BCL6 B-cell CLL/lymphoma 6 1.06152
SPP1 secreted phosphoprotein 1 1.0608
TIMP1 TIMP metallopeptidase inhibitor 1 1.06008
RAD50 RAD50 homolog (S. cerevisiae) 1.05972
BCL2L1 BCL2-like 1 1.05936
COL1A2 collagen, type I, alpha 2 1.059
COBL cordon-bleu WH2 repeat protein 1.0561
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 1.05573
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.05498
CD9 CD9 molecule 1.05461
C1S complement component 1, s subcomponent 1.05461
PDIA6 protein disulfide isomerase family A, member 6 1.05461
CYB5R1 cytochrome b5 reductase 1 1.05089
TLCD1 TLC domain containing 1 1.05089
F2 coagulation factor II (thrombin) 1.04831
GADD45A growth arrest and DNA-damage-inducible, alpha 1.04684
RPIA ribose 5-phosphate isomerase A 1.04611
FLI1 Fli-1 proto-oncogene, ETS transcription factor 1.04574
EPS15 epidermal growth factor receptor pathway substrate 15 1.04538
GATA3 GATA binding protein 3 1.04538
SH3BGRL SH3 domain binding glutamate-rich protein like 1.04538
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 1.04538
TMTC2 transmembrane and tetratricopeptide repeat containing 2 1.04538
INHBE inhibin, beta E 1.04352
SIGMAR1 sigma non-opioid intracellular receptor 1 1.04314
FOS FBJ murine osteosarcoma viral oncogene homolog 1.04163
PKLR pyruvate kinase, liver and RBC 1.04088
GSTO1 glutathione S-transferase omega 1 1.04088
MRAP melanocortin 2 receptor accessory protein 1.04088
CCAR1 cell division cycle and apoptosis regulator 1 1.04051
AKAP2 A kinase (PRKA) anchor protein 2 1.04014
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.03789
KDR kinase insert domain receptor 1.03789
FLT4 fms-related tyrosine kinase 4 1.03678
BMP5 bone morphogenetic protein 5 1.03641
CD38 CD38 molecule 1.03604
MAP2K6 mitogen-activated protein kinase kinase 6 1.03604
ADCY9 adenylate cyclase 9 1.03567
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 1.03567
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.0353
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.03456
JAK1 Janus kinase 1 1.03382
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 1.03382
LDLR low density lipoprotein receptor 1.03308
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 1.03122
COX8BP cytochrome c oxidase subunit VIIIB, pseudogene 1.03122
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 1.03046
PRKCA protein kinase C, alpha 1.02896
MGLL monoglyceride lipase 1.02746
GSTA3 glutathione S-transferase alpha 3 1.02671
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 1.02671
RPA3 replication protein A3, 14kDa 1.02634
PPAP2C phosphatidic acid phosphatase type 2C 1.02596
ACSM3 acyl-CoA synthetase medium-chain family member 3 1.02596
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 1.02559
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 1.02559
RB1 retinoblastoma 1 1.02522
UNG uracil-DNA glycosylase 1.02336
FMR1 fragile X mental retardation 1 1.02299
SCN1A sodium channel, voltage gated, type I alpha subunit 1.02188
GCK glucokinase (hexokinase 4) 1.02077
GHR growth hormone receptor 1.02077
KLF9 Kruppel-like factor 9 1.02077
MKI67 marker of proliferation Ki-67 1.02077
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 1.02077
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.0189
CYCS cytochrome c, somatic 1.01852
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 1.01776
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 1.01776
GSTA5 glutathione S-transferase alpha 5 1.01739
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 1.01739
MMP1 matrix metallopeptidase 1 1.01739
S100A6 S100 calcium binding protein A6 1.01701
PDE2A phosphodiesterase 2A, cGMP-stimulated 1.01701
FAM72A family with sequence similarity 72, member A 1.01512
ELOVL6 ELOVL fatty acid elongase 6 1.01286
COX7B cytochrome c oxidase subunit VIIb 1.01286
STARD4 StAR-related lipid transfer (START) domain containing 4 1.01286
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 1.01286
CTPS1 CTP synthase 1 1.01286
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 1.01249
TOP2A topoisomerase (DNA) II alpha 170kDa 1.01137
H2AFX H2A histone family, member X 1.01137
PLIN2 perilipin 2 1.01099
G0S2 G0/G1 switch 2 1.01099