Lupus Nephritis Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Glomerulonephritis associated with autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Lupus nephritis is histologically classified into 6 classes: class I - normal glomeruli, class II - pure mesangial alterations, class III - focal segmental glomerulonephritis, class IV - diffuse glomerulonephritis, class V - diffuse membranous glomerulonephritis, and class VI - advanced sclerosing glomerulonephritis (The World Health Organization classification 1982). (Experimental Factor Ontology, EFO_0005761)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D008181
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Genes

34 genes/proteins associated with the disease Lupus Nephritis from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 2.88009
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2.88009
MMP2 matrix metallopeptidase 2 2.88009
MMP9 matrix metallopeptidase 9 2.88009
IL4 interleukin 4 1.49407
TNF tumor necrosis factor 1.45299
CCL2 chemokine (C-C motif) ligand 2 1.43374
CCL11 chemokine (C-C motif) ligand 11 1.42374
IL6 interleukin 6 1.39394
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.31237
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.27905
VEGFA vascular endothelial growth factor A 1.25028
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.19835
LCN2 lipocalin 2 1.18259
GSTM1 glutathione S-transferase mu 1 1.14404
TGFB1 transforming growth factor, beta 1 1.14336
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.13552
BAX BCL2-associated X protein 1.13041
FAS Fas cell surface death receptor 1.13007
LTF lactotransferrin 1.12771
IL5 interleukin 5 1.12048
JUN jun proto-oncogene 1.11775
MPO myeloperoxidase 1.11536
FGA fibrinogen alpha chain 1.09716
BCL2 B-cell CLL/lymphoma 2 1.08797
IFNG interferon, gamma 1.08513
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.07234
MUCL1 mucin-like 1 1.06808
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.0561
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.04684
SPP1 secreted phosphoprotein 1 1.02783
GADD45A growth arrest and DNA-damage-inducible, alpha 1.01549
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.01324
TP53 tumor protein p53 1.01212