Lupus Erythematosus, Systemic Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart. (Human Disease Ontology, DOID_9074)
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Genes

682 genes associated with the Lupus Erythematosus, Systemic phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ABHD16A abhydrolase domain containing 16A
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACE angiotensin I converting enzyme
ACP1 acid phosphatase 1, soluble
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB3 adrenoceptor beta 3
AFF1 AF4/FMR2 family, member 1
AFF3 AF4/FMR2 family, member 3
AGER advanced glycosylation end product-specific receptor
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AIF1 allograft inflammatory factor 1
AIM2 absent in melanoma 2
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ANO3 anoctamin 3
ANXA5 annexin A5
APCS amyloid P component, serum
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
APOL1 apolipoprotein L, 1
APOO apolipoprotein O
AR androgen receptor
ARHGAP26 Rho GTPase activating protein 26
ARHGAP4 Rho GTPase activating protein 4
ARID5B AT rich interactive domain 5B (MRF1-like)
ATAT1 alpha tubulin acetyltransferase 1
ATF6B activating transcription factor 6 beta
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG5 autophagy related 5
ATG7 autophagy related 7
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
AVPR2 arginine vasopressin receptor 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAG6 BCL2-associated athanogene 6
BAK1 BCL2-antagonist/killer 1
BANK1 B-cell scaffold protein with ankyrin repeats 1
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BDNF brain-derived neurotrophic factor
BLK BLK proto-oncogene, Src family tyrosine kinase
BRD2 bromodomain containing 2
BTLA B and T lymphocyte associated
BTNL2 butyrophilin-like 2
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
C1R complement component 1, r subcomponent
C2 complement component 2
C2CD4B C2 calcium-dependent domain containing 4B
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
C4B complement component 4B (Chido blood group)
C5 complement component 5
C6ORF10 chromosome 6 open reading frame 10
C6ORF15 chromosome 6 open reading frame 15
C6ORF25 chromosome 6 open reading frame 25
C6ORF47 chromosome 6 open reading frame 47
C6ORF48 chromosome 6 open reading frame 48
C7 complement component 7
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CADPS Ca++-dependent secretion activator
CARD8 caspase recruitment domain family, member 8
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAT catalase
CBS cystathionine-beta-synthase
CCHCR1 coiled-coil alpha-helical rod protein 1
CCL14 chemokine (C-C motif) ligand 14
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CCL5 chemokine (C-C motif) ligand 5
CCL8 chemokine (C-C motif) ligand 8
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CD19 CD19 molecule
CD22 CD22 molecule
CD226 CD226 molecule
CD24 CD24 molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CD247 CD247 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD38 CD38 molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD80 CD80 molecule
CD86 CD86 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDSN corneodesmosin
CFB complement factor B
CFH complement factor H
CFHR1 complement factor H-related 1
CFHR2 complement factor H-related 2
CFHR3 complement factor H-related 3
CFHR4 complement factor H-related 4
CFHR5 complement factor H-related 5
CHD6 chromodomain helicase DNA binding protein 6
CIITA class II, major histocompatibility complex, transactivator
CLEC16A C-type lectin domain family 16, member A
CLIC1 chloride intracellular channel 1
CMTM4 CKLF-like MARVEL transmembrane domain containing 4
COL11A2 collagen, type XI, alpha 2
COMT catechol-O-methyltransferase
COTL1 coactosin-like F-actin binding protein 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRP C-reactive protein, pentraxin-related
CSMD1 CUB and Sushi multiple domains 1
CSNK2B casein kinase 2, beta polypeptide
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CUTA cutA divalent cation tolerance homolog (E. coli)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR5 chemokine (C-X-C motif) receptor 5
CYBA cytochrome b-245, alpha polypeptide
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DAXX death-domain associated protein
DDAH2 dimethylarginine dimethylaminohydrolase 2
DDR1 discoidin domain receptor tyrosine kinase 1
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DEFB1 defensin, beta 1
DEFB4A defensin, beta 4A
DHFR dihydrofolate reductase
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16
DIAPH3 diaphanous-related formin 3
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNASE1 deoxyribonuclease I
DNASE2 deoxyribonuclease II, lysosomal
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DPCR1 diffuse panbronchiolitis critical region 1
DRAM1 DNA-damage regulated autophagy modulator 1
EFNA5 ephrin-A5
EGFL8 EGF-like-domain, multiple 8
EGFR epidermal growth factor receptor
EGR2 early growth response 2
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ELF1 E74-like factor 1 (ets domain transcription factor)
ERBB3 erb-b2 receptor tyrosine kinase 3
ERC2 ELKS/RAB6-interacting/CAST family member 2
ERCC2 excision repair cross-complementation group 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FADD Fas (TNFRSF6)-associated via death domain
FAM167A family with sequence similarity 167, member A
FAM78B family with sequence similarity 78, member B
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCAR Fc fragment of IgA receptor
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCRL3 Fc receptor-like 3
FEN1 flap structure-specific endonuclease 1
FGB fibrinogen beta chain
FGF9 fibroblast growth factor 9
FGG fibrinogen gamma chain
FKBPL FK506 binding protein like
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLOT1 flotillin 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXJ1 forkhead box J1
FOXP3 forkhead box P3
FRS2 fibroblast growth factor receptor substrate 2
FYB FYN binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAS6 growth arrest-specific 6
GATA3 GATA binding protein 3
GIMAP5 GTPase, IMAP family member 5
GLDC glycine dehydrogenase (decarboxylating)
GNL1 guanine nucleotide binding protein-like 1
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPANK1 G patch domain and ankyrin repeats 1
GPR132 G protein-coupled receptor 132
GPSM3 G-protein signaling modulator 3
GSR glutathione reductase
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HAND1 heart and neural crest derivatives expressed 1
HAS2 hyaluronan synthase 2
HAVCR1 hepatitis A virus cellular receptor 1
HAVCR2 hepatitis A virus cellular receptor 2
HCFC1 host cell factor C1
HCG22 HLA complex group 22
HCG27 HLA complex group 27 (non-protein coding)
HCG9 HLA complex group 9 (non-protein coding)
HCLS1 hematopoietic cell-specific Lyn substrate 1
HCP5 HLA complex P5 (non-protein coding)
HFE hemochromatosis
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIPK1 homeodomain interacting protein kinase 1
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-F-AS1 HLA-F antisense RNA 1
HLA-G major histocompatibility complex, class I, G
HLA-K major histocompatibility complex, class I, K (pseudogene)
HLA-L major histocompatibility complex, class I, L (pseudogene)
HMHA1 histocompatibility (minor) HA-1
HMOX1 heme oxygenase 1
HRES1 HTLV-1 related endogenous sequence
HRH4 histamine receptor H4
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA1L heat shock 70kDa protein 1-like
HSPA2 heat shock 70kDa protein 2
IBD5 inflammatory bowel disease 5
ICA1 islet cell autoantigen 1, 69kDa
ICAM1 intercellular adhesion molecule 1
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
ICAM5 intercellular adhesion molecule 5, telencephalin
ICOS inducible T-cell co-stimulator
IER3 immediate early response 3
IFI16 interferon, gamma-inducible protein 16
IFIH1 interferon induced with helicase C domain 1
IFNA1 interferon, alpha 1
IFNA17 interferon, alpha 17
IFNA2 interferon, alpha 2
IFNA5 interferon, alpha 5
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IFNK interferon, kappa
IFNLR1 interferon, lambda receptor 1
IGF1R insulin-like growth factor 1 receptor
IGHM immunoglobulin heavy constant mu
IGLV@ immunoglobulin lambda variable cluster
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL10RB interleukin 10 receptor, beta
IL12A interleukin 12A
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL13 interleukin 13
IL16 interleukin 16
IL17A interleukin 17A
IL17F interleukin 17F
IL18 interleukin 18
IL19 interleukin 19
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL20 interleukin 20
IL21 interleukin 21
IL21R interleukin 21 receptor
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL24 interleukin 24
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL6 interleukin 6
IL6R interleukin 6 receptor
IL7R interleukin 7 receptor
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INHBC inhibin, beta C
IP6K3 inositol hexakisphosphate kinase 3
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK3 interleukin-1 receptor-associated kinase 3
IRF2 interferon regulatory factor 2
IRF3 interferon regulatory factor 3
IRF4 interferon regulatory factor 4
IRF5 interferon regulatory factor 5
IRF7 interferon regulatory factor 7
IRF8 interferon regulatory factor 8
IRGM immunity-related GTPase family, M
ITGA1 integrin, alpha 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JAK2 Janus kinase 2
JAZF1 JAZF zinc finger 1
JUN jun proto-oncogene
KDR kinase insert domain receptor
KIAA0319 KIAA0319
KIFC1 kinesin family member C1
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR2DP1 killer cell immunoglobulin-like receptor, two domains, pseudogene 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KLRC2 killer cell lectin-like receptor subfamily C, member 2
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KPNA1 karyopherin alpha 1 (importin alpha 5)
L1CAM L1 cell adhesion molecule
LAMA1 laminin, alpha 1
LAMC1 laminin, gamma 1 (formerly LAMB2)
LBH limb bud and heart development
LCE3B late cornified envelope 3B
LCE3C late cornified envelope 3C
LEMD2 LEM domain containing 2
LIG4 ligase IV, DNA, ATP-dependent
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LINC00336 long intergenic non-protein coding RNA 336
LINC01242 long intergenic non-protein coding RNA 1242
LINC01270 long intergenic non-protein coding RNA 1270
LINC01556 long intergenic non-protein coding RNA 1556
LMAN1 lectin, mannose-binding, 1
LOC440982 uncharacterized LOC440982
LPAR1 lysophosphatidic acid receptor 1
LRRC18 leucine rich repeat containing 18
LRRC20 leucine rich repeat containing 20
LRRC74A leucine rich repeat containing 74A
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LST1 leukocyte specific transcript 1
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
LUM lumican
LY6G5B lymphocyte antigen 6 complex, locus G5B
LY6G5C lymphocyte antigen 6 complex, locus G5C
LY6G6C lymphocyte antigen 6 complex, locus G6C
LY6G6E lymphocyte antigen 6 complex, locus G6E (pseudogene)
LY6G6F lymphocyte antigen 6 complex, locus G6F
LY9 lymphocyte antigen 9
LYN LYN proto-oncogene, Src family tyrosine kinase
LYPLA2P1 lysophospholipase II pseudogene 1
MAN2A1 mannosidase, alpha, class 2A, member 1
MAS1L MAS1 proto-oncogene like, G protein-coupled receptor
MAS1LP1 MAS1L pseudogene 1
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MAVS mitochondrial antiviral signaling protein
MBL2 mannose-binding lectin (protein C) 2, soluble
MCCD1 mitochondrial coiled-coil domain 1
MDC1 mediator of DNA-damage checkpoint 1
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MEFV Mediterranean fever
MERTK MER proto-oncogene, tyrosine kinase
METTL9 methyltransferase like 9
MFGE8 milk fat globule-EGF factor 8 protein
MICB MHC class I polypeptide-related sequence B
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR1468 microRNA 1468
MIR146A microRNA 146a
MIR499A microRNA 499a
MLN motilin
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MNDA myeloid cell nuclear differentiation antigen
MOG myelin oligodendrocyte glycoprotein
MPO myeloperoxidase
MRPS18B mitochondrial ribosomal protein S18B
MSH5 mutS homolog 5
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MUC21 mucin 21, cell surface associated
MYD88 myeloid differentiation primary response 88
MYL8P myosin, light chain 8, pseudogene
MYO18B myosin XVIIIB
MYO9B myosin IXB
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NAV2 neuron navigator 2
NBN nibrin
NCF2 neutrophil cytosolic factor 2
NCR3 natural cytotoxicity triggering receptor 3
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NELFE negative elongation factor complex member E
NEU1 sialidase 1 (lysosomal sialidase)
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKX2-5 NK2 homeobox 5
NLRC4 NLR family, CARD domain containing 4
NLRP1 NLR family, pyrin domain containing 1
NLRP3 NLR family, pyrin domain containing 3
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH4 notch 4
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRM nurim (nuclear envelope membrane protein)
NTNG1 netrin G1
OLIG3 oligodendrocyte transcription factor 3
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
OR11A1 olfactory receptor, family 11, subfamily A, member 1
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OR12D3 olfactory receptor, family 12, subfamily D, member 3
OR14J1 olfactory receptor, family 14, subfamily J, member 1
OR2B3 olfactory receptor, family 2, subfamily B, member 3
OR2H1 olfactory receptor, family 2, subfamily H, member 1
OR2H2 olfactory receptor, family 2, subfamily H, member 2
OR2J2 olfactory receptor, family 2, subfamily J, member 2
OR2J3 olfactory receptor, family 2, subfamily J, member 3
OR2W1 olfactory receptor, family 2, subfamily W, member 1
OR5V1 olfactory receptor, family 5, subfamily V, member 1
OSMR oncostatin M receptor
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PADI2 peptidyl arginine deiminase, type II
PADI4 peptidyl arginine deiminase, type IV
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PBX2 pre-B-cell leukemia homeobox 2
PDCD1 programmed cell death 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEX5L peroxisomal biogenesis factor 5-like
PFDN6 prefoldin subunit 6
PHF1 PHD finger protein 1
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHRF1 PHD and ring finger domains 1
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PON1 paraoxonase 1
PON3 paraoxonase 3
POU5F1 POU class 5 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PPP1R18 protein phosphatase 1, regulatory subunit 18
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPT2 palmitoyl-protein thioesterase 2
PRDM1 PR domain containing 1, with ZNF domain
PRKCB protein kinase C, beta
PRL prolactin
PRLR prolactin receptor
PRR3 proline rich 3
PRRC2A proline-rich coiled-coil 2A
PRRT1 proline-rich transmembrane protein 1
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMG2 proteasome (prosome, macropain) assembly chaperone 2
PSORS1C1 psoriasis susceptibility 1 candidate 1
PSORS1C2 psoriasis susceptibility 1 candidate 2
PTEN phosphatase and tensin homolog
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRM protein tyrosine phosphatase, receptor type, M
PTTG1 pituitary tumor-transforming 1
PXK PX domain containing serine/threonine kinase
PYHIN1 pyrin and HIN domain family, member 1
RABGAP1L RAB GTPase activating protein 1-like
RAD52 RAD52 homolog (S. cerevisiae)
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RAVER2 ribonucleoprotein, PTB-binding 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBMS3 RNA binding motif, single stranded interacting protein 3
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RENBP renin binding protein
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RING1 ring finger protein 1
RIPK2 receptor-interacting serine-threonine kinase 2
RNF39 ring finger protein 39
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RPP21 ribonuclease P/MRP 21kDa subunit
RPS18 ribosomal protein S18
RSBN1 round spermatid basic protein 1
RUNX1 runt-related transcription factor 1
RXRB retinoid X receptor, beta
SALL1 spalt-like transcription factor 1
SAPCD1 suppressor APC domain containing 1
SCUBE1 signal peptide, CUB domain, EGF-like 1
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTA2 surfactant associated 2
SH2B3 SH2B adaptor protein 3
SH2D1A SH2 domain containing 1A
SHBG sex hormone-binding globulin
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIGLECL1 SIGLEC family like 1
SIRT1 sirtuin 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLAMF1 signaling lymphocytic activation molecule family member 1
SLAMF7 SLAM family member 7
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC44A4 solute carrier family 44, member 4
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SOCS1 suppressor of cytokine signaling 1
SOD2 superoxide dismutase 2, mitochondrial
SOS1 son of sevenless homolog 1 (Drosophila)
SPP1 secreted phosphoprotein 1
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT5A signal transducer and activator of transcription 5A
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK17A serine/threonine kinase 17a
STK19 serine/threonine kinase 19
SUCLA2P1 succinate-CoA ligase, ADP-forming, beta subunit pseudogene 1
SUMO4 small ubiquitin-like modifier 4
SYNGAP1 synaptic Ras GTPase activating protein 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TAPBPL TAP binding protein-like
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBX21 T-box 21
TCF19 transcription factor 19
TET3 tet methylcytosine dioxygenase 3
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TGM6 transglutaminase 6
THRB-AS1 THRB antisense RNA 1
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TMEM187 transmembrane protein 187
TMEM39A transmembrane protein 39A
TNF tumor necrosis factor
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNIP1 TNFAIP3 interacting protein 1
TNIP2 TNFAIP3 interacting protein 2
TNPO3 transportin 3
TNXB tenascin XB
TP53 tumor protein p53
TPH2 tryptophan hydroxylase 2
TPMT thiopurine S-methyltransferase
TRADD TNFRSF1A-associated via death domain
TRAF1 TNF receptor-associated factor 1
TRAF3IP2 TRAF3 interacting protein 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAJ50 T cell receptor alpha joining 50
TRB T cell receptor beta locus
TRBV16 T cell receptor beta variable 16 (gene/pseudogene)
TREX1 three prime repair exonuclease 1
TREX2 three prime repair exonuclease 2
TRIM10 tripartite motif containing 10
TRIM15 tripartite motif containing 15
TRIM21 tripartite motif containing 21
TRIM26 tripartite motif containing 26
TRIM27 tripartite motif containing 27
TRIM31 tripartite motif containing 31
TRIM39 tripartite motif containing 39
TRIM40 tripartite motif containing 40
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase
TUBB tubulin, beta class I
TYK2 tyrosine kinase 2
TYMS thymidylate synthetase
UBASH3A ubiquitin associated and SH3 domain containing A
UBD ubiquitin D
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UHRF1BP1 UHRF1 binding protein 1
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VARS valyl-tRNA synthetase
VARS2 valyl-tRNA synthetase 2, mitochondrial
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VKORC1 vitamin K epoxide reductase complex, subunit 1
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
VSIG2 V-set and immunoglobulin domain containing 2
VTCN1 V-set domain containing T cell activation inhibitor 1
VWA7 von Willebrand factor A domain containing 7
WDFY4 WDFY family member 4
WDR46 WD repeat domain 46
XDH xanthine dehydrogenase
XKR6 XK, Kell blood group complex subunit-related family, member 6
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XXYLT1 xyloside xylosyltransferase 1
ZBTB20 zinc finger and BTB domain containing 20
ZBTB22 zinc finger and BTB domain containing 22
ZBTB9 zinc finger and BTB domain containing 9
ZFAND6 zinc finger, AN1-type domain 6
ZFP57 ZFP57 zinc finger protein
ZNF311 zinc finger protein 311
ZNRD1 zinc ribbon domain containing 1
ZNRD1-AS1 ZNRD1 antisense RNA 1
ZPBP2 zona pellucida binding protein 2