Lung squamous cell carcinoma_LUSC_TCGA-LA-A446-01A-21R-A24Z-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

397 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-LA-A446-01A-21R-A24Z-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AARS alanyl-tRNA synthetase
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACD adrenocortical dysplasia homolog (mouse)
ACER1 alkaline ceramidase 1
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADCK2 aarF domain containing kinase 2
ADCY8 adenylate cyclase 8 (brain)
AFF2 AF4/FMR2 family, member 2
AFG3L1P AFG3-like AAA ATPase 1, pseudogene
AFP alpha-fetoprotein
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9
AHSA2 AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast)
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALKBH7 alkB, alkylation repair homolog 7 (E. coli)
AMMECR1L AMMECR1-like
ANAPC1 anaphase promoting complex subunit 1
ANKRD11 ankyrin repeat domain 11
ANKRD20A11P ankyrin repeat domain 20 family, member A11, pseudogene
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGAP11A Rho GTPase activating protein 11A
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
ARMC5 armadillo repeat containing 5
ARMCX2 armadillo repeat containing, X-linked 2
ARMCX3 armadillo repeat containing, X-linked 3
ARMCX6 armadillo repeat containing, X-linked 6
ASF1A anti-silencing function 1A histone chaperone
ATG4D autophagy related 4D, cysteine peptidase
ATP10B ATPase, class V, type 10B
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
AVEN apoptosis, caspase activation inhibitor
AXDND1 axonemal dynein light chain domain containing 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BBS2 Bardet-Biedl syndrome 2
BRD2 bromodomain containing 2
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C15ORF39 chromosome 15 open reading frame 39
C1ORF229 chromosome 1 open reading frame 229
C2ORF76 chromosome 2 open reading frame 76
C3ORF22 chromosome 3 open reading frame 22
C6ORF1 chromosome 6 open reading frame 1
C7ORF49 chromosome 7 open reading frame 49
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CARD11 caspase recruitment domain family, member 11
CATSPER2P1 cation channel, sperm associated 2 pseudogene 1
CBWD2 COBW domain containing 2
CCDC115 coiled-coil domain containing 115
CCDC22 coiled-coil domain containing 22
CCDC93 coiled-coil domain containing 93
CCNA1 cyclin A1
CCSER1 coiled-coil serine-rich protein 1
CD99L2 CD99 molecule-like 2
CDAN1 codanin 1
CDK16 cyclin-dependent kinase 16
CENPJ centromere protein J
CENPN centromere protein N
CES1 carboxylesterase 1
CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5
CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
CKAP2L cytoskeleton associated protein 2-like
CMC4 C-x(9)-C motif containing 4
CPB1 carboxypeptidase B1 (tissue)
CRACR2A calcium release activated channel regulator 2A
CREB5 cAMP responsive element binding protein 5
CT83 cancer/testis antigen 83
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe)
CXORF40A chromosome X open reading frame 40A
CXORF40B chromosome X open reading frame 40B
CXORF56 chromosome X open reading frame 56
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
CYP4F29P cytochrome P450, family 4, subfamily F, polypeptide 29, pseudogene
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
D2HGDH D-2-hydroxyglutarate dehydrogenase
DCAF17 DDB1 and CUL4 associated factor 17
DCC DCC netrin 1 receptor
DCLK1 doublecortin-like kinase 1
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DHODH dihydroorotate dehydrogenase (quinone)
DIS3L DIS3 like exosome 3'-5' exoribonuclease
DMRT2 doublesex and mab-3 related transcription factor 2
DUS3L dihydrouridine synthase 3-like (S. cerevisiae)
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
E2F4 E2F transcription factor 4, p107/p130-binding
EDC4 enhancer of mRNA decapping 4
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific
ELF4 E74-like factor 4 (ets domain transcription factor)
ELK1 ELK1, member of ETS oncogene family
EMC8 ER membrane protein complex subunit 8
EMD emerin
EPPK1 epiplakin 1
ERCC3 excision repair cross-complementation group 3
EVI5L ecotropic viral integration site 5-like
EVPLL envoplakin-like
EXOSC3 exosome component 3
FAM122B family with sequence similarity 122B
FAM127A family with sequence similarity 127, member A
FAM127B family with sequence similarity 127, member B
FAM127C family with sequence similarity 127, member C
FAM192A family with sequence similarity 192, member A
FAM199X family with sequence similarity 199, X-linked
FAM201A family with sequence similarity 201, member A
FAM3A family with sequence similarity 3, member A
FAM58A family with sequence similarity 58, member A
FAN1 FANCD2/FANCI-associated nuclease 1
FAXC failed axon connections homolog (Drosophila)
FBXO11 F-box protein 11
FBXO17 F-box protein 17
FBXO27 F-box protein 27
FBXO41 F-box protein 41
FGD1 FYVE, RhoGEF and PH domain containing 1
FGFBP1 fibroblast growth factor binding protein 1
FLYWCH1 FLYWCH-type zinc finger 1
FMR1 fragile X mental retardation 1
FNDC8 fibronectin type III domain containing 8
G6PD glucose-6-phosphate dehydrogenase
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GCC1 GRIP and coiled-coil domain containing 1
GCLM glutamate-cysteine ligase, modifier subunit
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GCSH glycine cleavage system protein H (aminomethyl carrier)
GK3P glycerol kinase 3 pseudogene
GLA galactosidase, alpha
GMEB2 glucocorticoid modulatory element binding protein 2
GNL1 guanine nucleotide binding protein-like 1
GPKOW G patch domain and KOW motifs
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR135 G protein-coupled receptor 135
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GRIPAP1 GRIP1 associated protein 1
GSTM5 glutathione S-transferase mu 5
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa
H2AFX H2A histone family, member X
HAUS7 HAUS augmin-like complex, subunit 7
HBE1 hemoglobin, epsilon 1
HCFC1 host cell factor C1
HDAC10 histone deacetylase 10
HDAC6 histone deacetylase 6
HIST1H3C histone cluster 1, H3c
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1
HOOK2 hook microtubule-tethering protein 2
HOXD8 homeobox D8
HS6ST2 heparan sulfate 6-O-sulfotransferase 2
HSDL1 hydroxysteroid dehydrogenase like 1
HSF4 heat shock transcription factor 4
IDS iduronate 2-sulfatase
IFT27 intraflagellar transport 27
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IMP4 IMP4, U3 small nucleolar ribonucleoprotein
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IQSEC2 IQ motif and Sec7 domain 2
IRAK1 interleukin-1 receptor-associated kinase 1
IRF5 interferon regulatory factor 5
KANSL3 KAT8 regulatory NSL complex subunit 3
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KDM4B lysine (K)-specific demethylase 4B
KEAP1 kelch-like ECH-associated protein 1
KIAA0319 KIAA0319
KIF13A kinesin family member 13A
KIF7 kinesin family member 7
KLHDC4 kelch domain containing 4
KLHL13 kelch-like family member 13
KLHL36 kelch-like family member 36
KPNA1 karyopherin alpha 1 (importin alpha 5)
KRT15 keratin 15, type I
KRTAP20-2 keratin associated protein 20-2
KRTAP4-5 keratin associated protein 4-5
LAMP2 lysosomal-associated membrane protein 2
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LINC00116 long intergenic non-protein coding RNA 116
LMNTD2 lamin tail domain containing 2
LOC100130093 uncharacterized LOC100130093
LOC285629 uncharacterized LOC285629
LONP1 lon peptidase 1, mitochondrial
LRFN1 leucine rich repeat and fibronectin type III domain containing 1
LRRC29 leucine rich repeat containing 29
LRRC4 leucine rich repeat containing 4
LUZP2 leucine zipper protein 2
MAGEA6 melanoma antigen family A6
MAGEB18 melanoma antigen family B18
MAGEB6 melanoma antigen family B6
MAP1A microtubule-associated protein 1A
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAVS mitochondrial antiviral signaling protein
MBTPS1 membrane-bound transcription factor peptidase, site 1
MCFD2 multiple coagulation factor deficiency 2
MCTS1 malignant T cell amplified sequence 1
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1
MEPCE methylphosphate capping enzyme
MERTK MER proto-oncogene, tyrosine kinase
METAP1D methionyl aminopeptidase type 1D (mitochondrial)
METTL8 methyltransferase like 8
MID2 midline 2
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
MLYCD malonyl-CoA decarboxylase
MON1B MON1 secretory trafficking family member B
MRPS12 mitochondrial ribosomal protein S12
MSH6 mutS homolog 6
MTM1 myotubularin 1
MTMR1 myotubularin related protein 1
MTX2 metaxin 2
MYBBP1A MYB binding protein (P160) 1a
MYO5A myosin VA (heavy chain 12, myoxin)
MZT2B mitotic spindle organizing protein 2B
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NAIF1 nuclear apoptosis inducing factor 1
NAMPT nicotinamide phosphoribosyltransferase
NAV1 neuron navigator 1
NDRG4 NDRG family member 4
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
NELFCD negative elongation factor complex member C/D
NELL1 NEL-like 1 (chicken)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NIFK nucleolar protein interacting with the FHA domain of MKI67
NKAIN2 Na+/K+ transporting ATPase interacting 2
NKAP NFKB activating protein
NKRF NFKB repressing factor
NNT nicotinamide nucleotide transhydrogenase
NOM1 nucleolar protein with MIF4G domain 1
NPEPL1 aminopeptidase-like 1
NPR2 natriuretic peptide receptor 2
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NR0B1 nuclear receptor subfamily 0, group B, member 1
NRCAM neuronal cell adhesion molecule
NUP153 nucleoporin 153kDa
NXPE3 neurexophilin and PC-esterase domain family, member 3
OCRL oculocerebrorenal syndrome of Lowe
OR10A6 olfactory receptor, family 10, subfamily A, member 6 (gene/pseudogene)
OR2A14 olfactory receptor, family 2, subfamily A, member 14
OR2M4 olfactory receptor, family 2, subfamily M, member 4
OR51B4 olfactory receptor, family 51, subfamily B, member 4
OR51B5 olfactory receptor, family 51, subfamily B, member 5
OR51B6 olfactory receptor, family 51, subfamily B, member 6
OR5K3 olfactory receptor, family 5, subfamily K, member 3
OSGIN1 oxidative stress induced growth inhibitor 1
OTUD5 OTU deubiquitinase 5
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PARP16 poly (ADP-ribose) polymerase family, member 16
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PC pyruvate carboxylase
PCNXL3 pecanex-like 3 (Drosophila)
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIGF phosphatidylinositol glycan anchor biosynthesis, class F
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PIP5KL1 phosphatidylinositol-4-phosphate 5-kinase-like 1
PLXNA3 plexin A3
POLG polymerase (DNA directed), gamma
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR1E polymerase (RNA) I polypeptide E, 53kDa
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
PPARA peroxisome proliferator-activated receptor alpha
PPP1R21 protein phosphatase 1, regulatory subunit 21
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma
PPP6R2 protein phosphatase 6, regulatory subunit 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSD4 pleckstrin and Sec7 domain containing 4
PTGR1 prostaglandin reductase 1
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PUS10 pseudouridylate synthase 10
PVRL3 poliovirus receptor-related 3
PYCR2 pyrroline-5-carboxylate reductase family, member 2
PYCRL pyrroline-5-carboxylate reductase-like
PYDC2 pyrin domain containing 2
RAB11B RAB11B, member RAS oncogene family
RAB43 RAB43, member RAS oncogene family
RAD23A RAD23 homolog A (S. cerevisiae)
RANBP2 RAN binding protein 2
RANBP3 RAN binding protein 3
RASGEF1A RasGEF domain family, member 1A
RBM10 RNA binding motif protein 10
RBM11 RNA binding motif protein 11
RBMX2 RNA binding motif protein, X-linked 2
REPS1 RALBP1 associated Eps domain containing 1
RHOQ ras homolog family member Q
RINL Ras and Rab interactor-like
RNF217-AS1 RNF217 antisense RNA 1 (head to head)
RNF6 ring finger protein (C3H2C3 type) 6
RPE ribulose-5-phosphate-3-epimerase
RPL36A ribosomal protein L36a
RRAGB Ras-related GTP binding B
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
SAMD4B sterile alpha motif domain containing 4B
SAP130 Sin3A-associated protein, 130kDa
SARS2 seryl-tRNA synthetase 2, mitochondrial
SATL1 spermidine/spermine N1-acetyl transferase-like 1
SBF1 SET binding factor 1
SCAMP2 secretory carrier membrane protein 2
SFT2D3 SFT2 domain containing 3
SIRT2 sirtuin 2
SLC10A3 solute carrier family 10, member 3
SLC22A18 solute carrier family 22, member 18
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC25A51 solute carrier family 25, member 51
SLC25A51P1 solute carrier family 25, member 51 pseudogene 1
SLC35F5 solute carrier family 35, member F5
SLC35G6 solute carrier family 35, member G6
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SLC7A5P2 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2
SMIM10L2A small integral membrane protein 10 like 2A
SMIM10L2B small integral membrane protein 10 like 2B
SMO smoothened, frizzled class receptor
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SND1-IT1 SND1 intronic transcript 1
SNHG11 small nucleolar RNA host gene 11
SP3 Sp3 transcription factor
ST20-AS1 ST20 antisense RNA 1
STAG2 stromal antigen 2
STK26 serine/threonine protein kinase 26
STXBP5L syntaxin binding protein 5-like
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TAZ tafazzin
TBC1D22A TBC1 domain family, member 22A
TBC1D25 TBC1 domain family, member 25
TDP2 tyrosyl-DNA phosphodiesterase 2
TFE3 transcription factor binding to IGHM enhancer 3
TFG TRK-fused gene
TGM6 transglutaminase 6
THNSL2 threonine synthase-like 2 (S. cerevisiae)
THOC2 THO complex 2
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLX2 T-cell leukemia homeobox 2
TMEM105 transmembrane protein 105
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM177 transmembrane protein 177
TMEM185A transmembrane protein 185A
TMEM187 transmembrane protein 187
TMEM87B transmembrane protein 87B
TNPO3 transportin 3
TP53TG3B TP53 target 3B
TREX2 three prime repair exonuclease 2
TRIM16 tripartite motif containing 16
TRIM16L tripartite motif containing 16-like
TRMT10B tRNA methyltransferase 10 homolog B (S. cerevisiae)
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TSHB thyroid stimulating hormone, beta
TSN translin
TUBGCP4 tubulin, gamma complex associated protein 4
UBL4A ubiquitin-like 4A
UBQLN2 ubiquilin 2
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UNKL unkempt family zinc finger-like
UROC1 urocanate hydratase 1
USP10 ubiquitin specific peptidase 10
USP34 ubiquitin specific peptidase 34
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
UXS1 UDP-glucuronate decarboxylase 1
VAC14 Vac14 homolog (S. cerevisiae)
VARS2 valyl-tRNA synthetase 2, mitochondrial
VMAC vimentin-type intermediate filament associated coiled-coil protein
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VWA7 von Willebrand factor A domain containing 7
WDR13 WD repeat domain 13
WDR44 WD repeat domain 44
WNT5A wingless-type MMTV integration site family, member 5A
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPOT exportin, tRNA
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZC3H18 zinc finger CCCH-type containing 18
ZC3H8 zinc finger CCCH-type containing 8
ZDHHC23 zinc finger, DHHC-type containing 23
ZNF275 zinc finger protein 275
ZNF280C zinc finger protein 280C
ZNF282 zinc finger protein 282
ZNF319 zinc finger protein 319
ZNF414 zinc finger protein 414
ZNF449 zinc finger protein 449
ZNF512B zinc finger protein 512B
ZNF598 zinc finger protein 598
ZNF675 zinc finger protein 675
ZNF746 zinc finger protein 746
ZNF777 zinc finger protein 777
ZNF853 zinc finger protein 853
ZXDA zinc finger, X-linked, duplicated A
ZXDC ZXD family zinc finger C

low expression

Symbol Name
CGGBP1 CGG triplet repeat binding protein 1
THUMPD3 THUMP domain containing 3
ZNF654 zinc finger protein 654