Lung squamous cell carcinoma_LUSC_TCGA-98-A538-01A-11R-A262-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
Similar Terms
Downloads & Tools

Genes

433 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-98-A538-01A-11R-A262-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
ACO2 aconitase 2, mitochondrial
ACP1 acid phosphatase 1, soluble
ADAM20 ADAM metallopeptidase domain 20
ADAMTSL5 ADAMTS-like 5
ADGRG7 adhesion G protein-coupled receptor G7
ADRBK1 adrenergic, beta, receptor kinase 1
ADSSL1 adenylosuccinate synthase like 1
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMER1 APC membrane recruitment protein 1
ANKRD13C ankyrin repeat domain 13C
ANKRD17 ankyrin repeat domain 17
ANXA11 annexin A11
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
APOPT1 apoptogenic 1, mitochondrial
ARF6 ADP-ribosylation factor 6
ARHGAP19 Rho GTPase activating protein 19
ARHGAP35 Rho GTPase activating protein 35
ARHGAP5 Rho GTPase activating protein 5
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARL4C ADP-ribosylation factor-like 4C
ARSK arylsulfatase family, member K
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
AUTS2 autism susceptibility candidate 2
BAG5 BCL2-associated athanogene 5
BCAS2 breast carcinoma amplified sequence 2
BCL2L12 BCL2-like 12 (proline rich)
BCOR BCL6 corepressor
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2
BMP7 bone morphogenetic protein 7
BRD1 bromodomain containing 1
BRDT bromodomain, testis-specific
BRMS1 breast cancer metastasis suppressor 1
BTBD6 BTB (POZ) domain containing 6
BTC betacellulin
C10ORF12 chromosome 10 open reading frame 12
C11ORF24 chromosome 11 open reading frame 24
C12ORF60 chromosome 12 open reading frame 60
C14ORF2 chromosome 14 open reading frame 2
C14ORF79 chromosome 14 open reading frame 79
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C2ORF69 chromosome 2 open reading frame 69
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CAPN1 calpain 1, (mu/I) large subunit
CAPN14 calpain 14
CBWD2 COBW domain containing 2
CCBL2 cysteine conjugate-beta lyase 2
CCDC134 coiled-coil domain containing 134
CCDC47 coiled-coil domain containing 47
CCDC85C coiled-coil domain containing 85C
CCNJ cyclin J
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDCA4 cell division cycle associated 4
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CEP170B centrosomal protein 170B
CEP55 centrosomal protein 55kDa
CERK ceramide kinase
CHUK conserved helix-loop-helix ubiquitous kinase
CKB creatine kinase, brain
CLCN5 chloride channel, voltage-sensitive 5
CLDN12 claudin 12
CLEC2L C-type lectin domain family 2, member L
CLGN calmegin
CLSTN1 calsyntenin 1
CNBD2 cyclic nucleotide binding domain containing 2
COBLL1 cordon-bleu WH2 repeat protein-like 1
COPG2 coatomer protein complex, subunit gamma 2
CORO1B coronin, actin binding protein, 1B
CORO2A coronin, actin binding protein, 2A
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
COX18 COX18 cytochrome c oxidase assembly factor
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPA6 carboxypeptidase A6
CREB1 cAMP responsive element binding protein 1
CRYBG3 beta-gamma crystallin domain containing 3
CSNK1G2 casein kinase 1, gamma 2
CSNK1G3 casein kinase 1, gamma 3
CTTN cortactin
CUEDC1 CUE domain containing 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXORF38 chromosome X open reading frame 38
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DCK deoxycytidine kinase
DENND2C DENN/MADD domain containing 2C
DEPDC7 DEP domain containing 7
DEPTOR DEP domain containing MTOR-interacting protein
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DMC1 DNA meiotic recombinase 1
DMRTA2 DMRT-like family A2
DNMBP dynamin binding protein
DPP3 dipeptidyl-peptidase 3
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DSC2 desmocollin 2
DSC3 desmocollin 3
DSCR4 Down syndrome critical region 4
DSCR8 Down syndrome critical region 8
DSG2 desmoglein 2
DSG3 desmoglein 3
DST dystonin
EFNA2 ephrin-A2
EHF ets homologous factor
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ELL2 elongation factor, RNA polymerase II, 2
EMC1 ER membrane protein complex subunit 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHA6 EPH receptor A6
ERLIN1 ER lipid raft associated 1
ESPN espin
EXOC5 exocyst complex component 5
EXOC6 exocyst complex component 6
FADD Fas (TNFRSF6)-associated via death domain
FAM102B family with sequence similarity 102, member B
FAM110C family with sequence similarity 110, member C
FAM117B family with sequence similarity 117, member B
FAM126B family with sequence similarity 126, member B
FAM83E family with sequence similarity 83, member E
FAM83F family with sequence similarity 83, member F
FBXO34 F-box protein 34
FBXO45 F-box protein 45
FOXP2 forkhead box P2
FOXQ1 forkhead box Q1
FRA10AC1 fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1
FRAT2 frequently rearranged in advanced T-cell lymphomas 2
FRRS1 ferric-chelate reductase 1
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GAGE1 G antigen 1
GAGE10 G antigen 10
GAGE2D G antigen 2D
GAGE4 G antigen 4
GAL3ST2 galactose-3-O-sulfotransferase 2
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GBP6 guanylate binding protein family, member 6
GEN1 GEN1 Holliday junction 5' flap endonuclease
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPR157 G protein-coupled receptor 157
GPSM2 G-protein signaling modulator 2
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRAMD4 GRAM domain containing 4
GRB2 growth factor receptor-bound protein 2
GRSF1 G-rich RNA sequence binding factor 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
H3F3C H3 histone, family 3C
HELLS helicase, lymphoid-specific
HELZ helicase with zinc finger
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIST1H2AD histone cluster 1, H2ad
HLF hepatic leukemia factor
HOMER2 homer scaffolding protein 2
HOOK1 hook microtubule-tethering protein 1
HPS1 Hermansky-Pudlak syndrome 1
HRAS Harvey rat sarcoma viral oncogene homolog
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6
HSPA2 heat shock 70kDa protein 2
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IGHMBP2 immunoglobulin mu binding protein 2
IKZF2 IKAROS family zinc finger 2 (Helios)
JAG2 jagged 2
KCNK10 potassium channel, two pore domain subfamily K, member 10
KDM2A lysine (K)-specific demethylase 2A
KIAA1468 KIAA1468
KIF1B kinesin family member 1B
KLC1 kinesin light chain 1
KLF3 Kruppel-like factor 3 (basic)
KRT13 keratin 13, type I
KRT15 keratin 15, type I
L2HGDH L-2-hydroxyglutarate dehydrogenase
LAMA5 laminin, alpha 5
LCOR ligand dependent nuclear receptor corepressor
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LMF2 lipase maturation factor 2
LOC100133050 glucuronidase, beta pseudogene
LOC440461 Rho GTPase activating protein 27 pseudogene
LPAR3 lysophosphatidic acid receptor 3
LPP LIM domain containing preferred translocation partner in lipoma
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRP5 low density lipoprotein receptor-related protein 5
LRRC16A leucine rich repeat containing 16A
LRRC24 leucine rich repeat containing 24
LRRC8B leucine rich repeat containing 8 family, member B
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LYPD6 LY6/PLAUR domain containing 6
MAB21L3 mab-21-like 3 (C. elegans)
MAEL maelstrom spermatogenic transposon silencer
MAN1A2 mannosidase, alpha, class 1A, member 2
MAOA monoamine oxidase A
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK13 mitogen-activated protein kinase 13
MAPK6 mitogen-activated protein kinase 6
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK3 MAP/microtubule affinity-regulating kinase 3
MCM3AP minichromosome maintenance complex component 3 associated protein
MED16 mediator complex subunit 16
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MFN2 mitofusin 2
MGC2889 uncharacterized protein MGC2889
MID1 midline 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MOB1B MOB kinase activator 1B
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRPL11 mitochondrial ribosomal protein L11
MRPL21 mitochondrial ribosomal protein L21
MRPL44 mitochondrial ribosomal protein L44
MRPL57 mitochondrial ribosomal protein L57
MSGN1 mesogenin 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MYOF myoferlin
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D
NCALD neurocalcin delta
NCAPH2 non-SMC condensin II complex, subunit H2
NDC1 NDC1 transmembrane nucleoporin
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NFIA nuclear factor I/A
NKX2-3 NK2 homeobox 3
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRXN3 neurexin 3
NTS neurotensin
NUP205 nucleoporin 205kDa
NUP50 nucleoporin 50kDa
NXPH4 neurexophilin 4
NYNRIN NYN domain and retroviral integrase containing
OR8D2 olfactory receptor, family 8, subfamily D, member 2 (gene/pseudogene)
ORAOV1 oral cancer overexpressed 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PASD1 PAS domain containing 1
PAX9 paired box 9
PC pyruvate carboxylase
PCDHB13 protocadherin beta 13
PCDHB6 protocadherin beta 6
PDLIM1 PDZ and LIM domain 1
PER3 period circadian clock 3
PGAM1 phosphoglycerate mutase 1 (brain)
PGAM4 phosphoglycerate mutase family member 4
PGAP2 post-GPI attachment to proteins 2
PHAX phosphorylated adaptor for RNA export
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PHTF2 putative homeodomain transcription factor 2
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIAS2 protein inhibitor of activated STAT, 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PITX1 paired-like homeodomain 1
PITX2 paired-like homeodomain 2
PIWIL2 piwi-like RNA-mediated gene silencing 2
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PKP3 plakophilin 3
PLCE1 phospholipase C, epsilon 1
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLXNA2 plexin A2
PLXNB2 plexin B2
PNMA5 paraneoplastic Ma antigen family member 5
POMZP3 POM121 and ZP3 fusion
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPIF peptidylprolyl isomerase F
PPP4R1 protein phosphatase 4, regulatory subunit 1
PPP6R3 protein phosphatase 6, regulatory subunit 3
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae)
PRKCH protein kinase C, eta
PRMT2 protein arginine methyltransferase 2
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PTDSS2 phosphatidylserine synthase 2
PTN pleiotrophin
PVRL3 poliovirus receptor-related 3
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB1B RAB1B, member RAS oncogene family
RAB23 RAB23, member RAS oncogene family
RAB40C RAB40C, member RAS oncogene family
RAD9A RAD9 homolog A (S. pombe)
RBBP8 retinoblastoma binding protein 8
RBM28 RNA binding motif protein 28
RCAN3 RCAN family member 3
RCE1 Ras converting CAAX endopeptidase 1
RECQL4 RecQ protein-like 4
RERG RAS-like, estrogen-regulated, growth inhibitor
RFESD Rieske (Fe-S) domain containing
RGMA repulsive guidance molecule family member a
RIC8A RIC8 guanine nucleotide exchange factor A
RIN1 Ras and Rab interactor 1
RIOK3 RIO kinase 3
RNF126 ring finger protein 126
RNF32 ring finger protein 32
RNH1 ribonuclease/angiogenin inhibitor 1
RPL23AP82 ribosomal protein L23a pseudogene 82
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RPUSD1 RNA pseudouridylate synthase domain containing 1
RREB1 ras responsive element binding protein 1
RRM1 ribonucleotide reductase M1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RSBN1 round spermatid basic protein 1
RSBN1L round spermatid basic protein 1-like
RTCA RNA 3'-terminal phosphate cyclase
RUFY3 RUN and FYVE domain containing 3
SBF1 SET binding factor 1
SCARB2 scavenger receptor class B, member 2
SCO2 SCO2 cytochrome c oxidase assembly protein
SDAD1 SDA1 domain containing 1
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEPHS2 selenophosphate synthetase 2
SERBP1 SERPINE1 mRNA binding protein 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SETD9 SET domain containing 9
SGPP2 sphingosine-1-phosphate phosphatase 2
SHROOM2 shroom family member 2
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIRT3 sirtuin 3
SIVA1 SIVA1, apoptosis-inducing factor
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A6 solute carrier family 16, member 6
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7
SLC6A10P solute carrier family 6 (neurotransmitter transporter), member 10, pseudogene
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SNORA51 small nucleolar RNA, H/ACA box 51
SPATC1L spermatogenesis and centriole associated 1-like
SPDL1 spindle apparatus coiled-coil protein 1
SPOPL speckle-type POZ protein-like
SPTBN2 spectrin, beta, non-erythrocytic 2
SSFA2 sperm specific antigen 2
SSTR5 somatostatin receptor 5
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STIM1 stromal interaction molecule 1
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TBC1D12 TBC1 domain family, member 12
TBL1X transducin (beta)-like 1X-linked
TCTN3 tectonic family member 3
TEX2 testis expressed 2
THAP6 THAP domain containing 6
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast)
TM9SF3 transmembrane 9 superfamily member 3
TMEM168 transmembrane protein 168
TMEM184B transmembrane protein 184B
TMEM88B transmembrane protein 88B
TMOD3 tropomodulin 3 (ubiquitous)
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNIK TRAF2 and NCK interacting kinase
TNPO3 transportin 3
TNRC6B trinucleotide repeat containing 6B
TOB2 transducer of ERBB2, 2
TOLLIP toll interacting protein
TPD52 tumor protein D52
TRABD TraB domain containing
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
TRIM47 tripartite motif containing 47
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UBIAD1 UbiA prenyltransferase domain containing 1
UBTD1 ubiquitin domain containing 1
UNC93B1 unc-93 homolog B1 (C. elegans)
USP3 ubiquitin specific peptidase 3
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
VAV3 vav 3 guanine nucleotide exchange factor
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WDFY1 WD repeat and FYVE domain containing 1
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR18 WD repeat domain 18
WDR3 WD repeat domain 3
WNT7B wingless-type MMTV integration site family, member 7B
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YTHDC1 YTH domain containing 1
ZBED4 zinc finger, BED-type containing 4
ZBTB42 zinc finger and BTB domain containing 42
ZCCHC2 zinc finger, CCHC domain containing 2
ZDHHC16 zinc finger, DHHC-type containing 16
ZDHHC20 zinc finger, DHHC-type containing 20
ZFAND3 zinc finger, AN1-type domain 3
ZFP28 ZFP28 zinc finger protein
ZFYVE21 zinc finger, FYVE domain containing 21
ZHX1 zinc fingers and homeoboxes 1
ZIK1 zinc finger protein interacting with K protein 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF112 zinc finger protein 112
ZNF134 zinc finger protein 134
ZNF221 zinc finger protein 221
ZNF225 zinc finger protein 225
ZNF229 zinc finger protein 229
ZNF235 zinc finger protein 235
ZNF274 zinc finger protein 274
ZNF28 zinc finger protein 28
ZNF285 zinc finger protein 285
ZNF329 zinc finger protein 329
ZNF395 zinc finger protein 395
ZNF429 zinc finger protein 429
ZNF436 zinc finger protein 436
ZNF470 zinc finger protein 470
ZNF473 zinc finger protein 473
ZNF518A zinc finger protein 518A
ZNF542P zinc finger protein 542, pseudogene
ZNF560 zinc finger protein 560
ZNF582 zinc finger protein 582
ZNF614 zinc finger protein 614
ZNF615 zinc finger protein 615
ZNF616 zinc finger protein 616
ZNF77 zinc finger protein 77
ZNF845 zinc finger protein 845
ZZZ3 zinc finger, ZZ-type containing 3

low expression

Symbol Name
CHIC1 cysteine-rich hydrophobic domain 1
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32
LARP7 La ribonucleoprotein domain family, member 7
MLYCD malonyl-CoA decarboxylase
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
STX5 syntaxin 5
TMCO4 transmembrane and coiled-coil domains 4
TRIM38 tripartite motif containing 38