Lung squamous cell carcinoma_LUSC_TCGA-92-8064-01A-11R-2247-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

416 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-92-8064-01A-11R-2247-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ABHD4 abhydrolase domain containing 4
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACIN1 apoptotic chromatin condensation inducer 1
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALKBH8 alkB, alkylation repair homolog 8 (E. coli)
ALMS1P Alstrom syndrome 1 pseudogene
AMDHD1 amidohydrolase domain containing 1
ANO1 anoctamin 1, calcium activated chloride channel
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOL1 apolipoprotein L, 1
APOL2 apolipoprotein L, 2
APOL4 apolipoprotein L, 4
APOL6 apolipoprotein L, 6
ARHGAP5 Rho GTPase activating protein 5
ARHGEF39 Rho guanine nucleotide exchange factor (GEF) 39
ARID2 AT rich interactive domain 2 (ARID, RFX-like)
ARID3C AT rich interactive domain 3C (BRIGHT-like)
ARRDC5 arrestin domain containing 5
ATP10B ATPase, class V, type 10B
ATXN2L ataxin 2-like
BATF2 basic leucine zipper transcription factor, ATF-like 2
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BCKDK branched chain ketoacid dehydrogenase kinase
BRMS1L breast cancer metastasis-suppressor 1-like
C11ORF30 chromosome 11 open reading frame 30
C14ORF119 chromosome 14 open reading frame 119
C15ORF53 chromosome 15 open reading frame 53
C16ORF58 chromosome 16 open reading frame 58
C17ORF105 chromosome 17 open reading frame 105
C1ORF110 chromosome 1 open reading frame 110
C21ORF91 chromosome 21 open reading frame 91
C2CD3 C2 calcium-dependent domain containing 3
C4ORF50 chromosome 4 open reading frame 50
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC22 coiled-coil domain containing 22
CCDC86 coiled-coil domain containing 86
CCL1 chemokine (C-C motif) ligand 1
CCL26 chemokine (C-C motif) ligand 26
CCL5 chemokine (C-C motif) ligand 5
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD274 CD274 molecule
CD38 CD38 molecule
CD6 CD6 molecule
CD7 CD7 molecule
CD8A CD8a molecule
CD96 CD96 molecule
CDC25B cell division cycle 25B
CDC37L1 cell division cycle 37-like 1
CDCA2 cell division cycle associated 2
CDH16 cadherin 16, KSP-cadherin
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CEP44 centrosomal protein 44kDa
CEP76 centrosomal protein 76kDa
CES1P1 carboxylesterase 1 pseudogene 1
CES2 carboxylesterase 2
CES3 carboxylesterase 3
CHD8 chromodomain helicase DNA binding protein 8
CHMP4A charged multivesicular body protein 4A
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CIDEB cell death-inducing DFFA-like effector b
CLASP1 cytoplasmic linker associated protein 1
CLLU1 chronic lymphocytic leukemia up-regulated 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNTLN centlein, centrosomal protein
CRTAM cytotoxic and regulatory T cell molecule
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CWF19L2 CWF19-like 2, cell cycle control (S. pombe)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR6 chemokine (C-X-C motif) receptor 6
CXORF40A chromosome X open reading frame 40A
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
CYTIP cytohesin 1 interacting protein
DCAF10 DDB1 and CUL4 associated factor 10
DCAF11 DDB1 and CUL4 associated factor 11
DCAF12 DDB1 and CUL4 associated factor 12
DCTN3 dynactin 3 (p22)
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DHRS4 dehydrogenase/reductase (SDR family) member 4
DHRS4-AS1 DHRS4 antisense RNA 1
DHRS4L1 dehydrogenase/reductase (SDR family) member 4 like 1
DHRS4L2 dehydrogenase/reductase (SDR family) member 4 like 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DPF1 D4, zinc and double PHD fingers family 1
DTD2 D-tyrosyl-tRNA deacylase 2 (putative)
DTX3L deltex 3 like, E3 ubiquitin ligase
DUSP2 dual specificity phosphatase 2
DZIP1L DAZ interacting zinc finger protein 1-like
EAPP E2F-associated phosphoprotein
EFS embryonal Fyn-associated substrate
EMC9 ER membrane protein complex subunit 9
EOMES eomesodermin
ETV7 ets variant 7
EXOSC3 exosome component 3
FADD Fas (TNFRSF6)-associated via death domain
FAM120C family with sequence similarity 120C
FAM161A family with sequence similarity 161, member A
FAM163B family with sequence similarity 163, member B
FAM177A1 family with sequence similarity 177, member A1
FAM201A family with sequence similarity 201, member A
FAM214B family with sequence similarity 214, member B
FAM219A family with sequence similarity 219, member A
FAM71B family with sequence similarity 71, member B
FAM72D family with sequence similarity 72, member D
FANCG Fanconi anemia, complementation group G
FASLG Fas ligand (TNF superfamily, member 6)
FBN2 fibrillin 2
FBXO10 F-box protein 10
FBXO31 F-box protein 31
FCRL6 Fc receptor-like 6
FGF19 fibroblast growth factor 19
FZD10 frizzled class receptor 10
G2E3 G2/M-phase specific E3 ubiquitin protein ligase
G6PD glucose-6-phosphate dehydrogenase
GAB1 GRB2-associated binding protein 1
GALT galactose-1-phosphate uridylyltransferase
GBA2 glucosidase, beta (bile acid) 2
GBP1 guanylate binding protein 1, interferon-inducible
GBP2 guanylate binding protein 2, interferon-inducible
GBP5 guanylate binding protein 5
GFI1 growth factor independent 1 transcription repressor
GLI2 GLI family zinc finger 2
GMPR2 guanosine monophosphate reductase 2
GPR171 G protein-coupled receptor 171
GPR174 G protein-coupled receptor 174
GRAP2 GRB2-related adaptor protein 2
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GSG2 germ cell associated 2 (haspin)
GSTM3 glutathione S-transferase mu 3 (brain)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
HAUS7 HAUS augmin-like complex, subunit 7
HEATR5A HEAT repeat containing 5A
HEATR9 HEAT repeat containing 9
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HINT2 histidine triad nucleotide binding protein 2
HIST3H3 histone cluster 3, H3
HOMEZ homeobox and leucine zipper encoding
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IFI44L interferon-induced protein 44-like
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFNG interferon, gamma
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL12RB1 interleukin 12 receptor, beta 1
IL12RB2 interleukin 12 receptor, beta 2
IL18BP interleukin 18 binding protein
IL25 interleukin 25
INCENP inner centromere protein antigens 135/155kDa
IPO4 importin 4
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
IRF9 interferon regulatory factor 9
ISG20 interferon stimulated exonuclease gene 20kDa
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
JAKMIP1 janus kinase and microtubule interacting protein 1
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KCNK18 potassium channel, two pore domain subfamily K, member 18
KDM4C lysine (K)-specific demethylase 4C
KGFLP1 fibroblast growth factor 7 pseudogene
KHNYN KH and NYN domain containing
KIAA0391 KIAA0391
KIAA2026 KIAA2026
KIF16B kinesin family member 16B
KIF22 kinesin family member 22
KIF24 kinesin family member 24
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
KLRC2 killer cell lectin-like receptor subfamily C, member 2
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LAG3 lymphocyte-activation gene 3
LAX1 lymphocyte transmembrane adaptor 1
LGI3 leucine-rich repeat LGI family, member 3
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LIPT2 lipoyl(octanoyl) transferase 2 (putative)
LOC440896 uncharacterized LOC440896
LOC729609 uncharacterized LOC729609
LRCH2 leucine-rich repeats and calponin homology (CH) domain containing 2
LRRC16B leucine rich repeat containing 16B
LRRTM2 leucine rich repeat transmembrane neuronal 2
LTB4R leukotriene B4 receptor
LTB4R2 leukotriene B4 receptor 2
LUZP2 leucine zipper protein 2
MBD5 methyl-CpG binding domain protein 5
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1
MDP1 magnesium-dependent phosphatase 1
MECP2 methyl CpG binding protein 2
MELK maternal embryonic leucine zipper kinase
METTL17 methyltransferase like 17
METTL3 methyltransferase like 3
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type
MSANTD4 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
MTMR1 myotubularin related protein 1
MTSS1 metastasis suppressor 1
MYH11 myosin, heavy chain 11, smooth muscle
MYH14 myosin, heavy chain 14, non-muscle
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYO7A myosin VIIA
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit
NAV1 neuron navigator 1
NBPF15 neuroblastoma breakpoint family, member 15
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGDN neuroguidin, EIF4E binding protein
NIFK nucleolar protein interacting with the FHA domain of MKI67
NKG7 natural killer cell granule protein 7
NLRC3 NLR family, CARD domain containing 3
NLRC5 NLR family, CARD domain containing 5
NLRP6 NLR family, pyrin domain containing 6
NOA1 nitric oxide associated 1
NOP9 NOP9 nucleolar protein
NPAS1 neuronal PAS domain protein 1
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NPR2 natriuretic peptide receptor 2
NRL neural retina leucine zipper
NRXN2 neurexin 2
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OR2A1 olfactory receptor, family 2, subfamily A, member 1
OR2A4 olfactory receptor, family 2, subfamily A, member 4
OR2A9P olfactory receptor, family 2, subfamily A, member 9 pseudogene
OR5B21 olfactory receptor, family 5, subfamily B, member 21
ORAI3 ORAI calcium release-activated calcium modulator 3
ORAOV1 oral cancer overexpressed 1
OTOP2 otopetrin 2
OXA1L oxidase (cytochrome c) assembly 1-like
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
PAPOLG poly(A) polymerase gamma
PAPPA2 pappalysin 2
PARP10 poly (ADP-ribose) polymerase family, member 10
PARP14 poly (ADP-ribose) polymerase family, member 14
PARP2 poly (ADP-ribose) polymerase 2
PARP9 poly (ADP-ribose) polymerase family, member 9
PATE3 prostate and testis expressed 3
PC pyruvate carboxylase
PCDHGA10 protocadherin gamma subfamily A, 10
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PEX13 peroxisomal biogenesis factor 13
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PNCK pregnancy up-regulated nonubiquitous CaM kinase
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POLR1E polymerase (RNA) I polypeptide E, 53kDa
POU2AF1 POU class 2 associating factor 1
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPME1 protein phosphatase methylesterase 1
PPP1R3E protein phosphatase 1, regulatory subunit 3E
PRAMEF11 PRAME family member 11
PRAMEF4 PRAME family member 4
PRAMEF5 PRAME family member 5
PRAMEF6 PRAME family member 6
PRAMEF9 PRAME family member 9
PRDM1 PR domain containing 1, with ZNF domain
PRF1 perforin 1 (pore forming protein)
PRG1 p53-responsive gene 1
PRKY protein kinase, Y-linked, pseudogene
PRMT5 protein arginine methyltransferase 5
PROCR protein C receptor, endothelial
PRR14 proline rich 14
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PTK2B protein tyrosine kinase 2 beta
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PYHIN1 pyrin and HIN domain family, member 1
QRFPR pyroglutamylated RFamide peptide receptor
QTRT1 queuine tRNA-ribosyltransferase 1
RAB2B RAB2B, member RAS oncogene family
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RALB v-ral simian leukemia viral oncogene homolog B
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RANBP6 RAN binding protein 6
RAP1GAP2 RAP1 GTPase activating protein 2
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBM15 RNA binding motif protein 15
RBM19 RNA binding motif protein 19
RBM23 RNA binding motif protein 23
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RENBP renin binding protein
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RGS16 regulator of G-protein signaling 16
RGS6 regulator of G-protein signaling 6
RIC1 RAB6A GEF complex partner 1
RNF114 ring finger protein 114
RNF169 ring finger protein 169
RNF213 ring finger protein 213
RNF31 ring finger protein 31
RNF38 ring finger protein 38
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RPP25L ribonuclease P/MRP 25kDa subunit-like
SAMD8 sterile alpha motif domain containing 8
SBNO1 strawberry notch homolog 1 (Drosophila)
SCAF11 SR-related CTD-associated factor 11
SCN3B sodium channel, voltage gated, type III beta subunit
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1
SECTM1 secreted and transmembrane 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETBP1 SET binding protein 1
SFMBT2 Scm-like with four mbt domains 2
SGK223 homolog of rat pragma of Rnd2
SIGLEC10 sialic acid binding Ig-like lectin 10
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRPG signal-regulatory protein gamma
SLA2 Src-like-adaptor 2
SLC10A3 solute carrier family 10, member 3
SLC22A20 solute carrier family 22, member 20
SLC22A25 solute carrier family 22, member 25
SLC22A9 solute carrier family 22 (organic anion transporter), member 9
SLC25A51 solute carrier family 25, member 51
SLC25A51P1 solute carrier family 25, member 51 pseudogene 1
SLC25A52 solute carrier family 25, member 52
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SLFN12L schlafen family member 12-like
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMG6 SMG6 nonsense mediated mRNA decay factor
SMTNL1 smoothelin-like 1
SNORA51 small nucleolar RNA, H/ACA box 51
SNORA65 small nucleolar RNA, H/ACA box 65
SNORA72 small nucleolar RNA, H/ACA box 72
SNX6 sorting nexin 6
SOS1 son of sevenless homolog 1 (Drosophila)
SOX5 SRY (sex determining region Y)-box 5
SP110 SP110 nuclear body protein
SPIN2B spindlin family, member 2B
SPNS1 spinster homolog 1 (Drosophila)
SPTSSA serine palmitoyltransferase, small subunit A
SRCAP Snf2-related CREBBP activator protein
SRP54 signal recognition particle 54kDa
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STOML2 stomatin (EPB72)-like 2
STOX2 storkhead box 2
STRN3 striatin, calmodulin binding protein 3
STX1B syntaxin 1B
STX4 syntaxin 4
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SYNDIG1 synapse differentiation inducing 1
TAGAP T-cell activation RhoGTPase activating protein
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D31 TBC1 domain family, member 31
TBX21 T-box 21
TCP11L1 t-complex 11, testis-specific-like 1
TESK1 testis-specific kinase 1
THTPA thiamine triphosphatase
TIGIT T cell immunoreceptor with Ig and ITIM domains
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TM9SF1 transmembrane 9 superfamily member 1
TMEM185B transmembrane protein 185B
TMEM55B transmembrane protein 55B
TMEM8B transmembrane protein 8B
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast)
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TOX4 TOX high mobility group box family member 4
TRAFD1 TRAF-type zinc finger domain containing 1
TREX1 three prime repair exonuclease 1
TRIM21 tripartite motif containing 21
TRIM22 tripartite motif containing 22
TRMT10B tRNA methyltransferase 10 homolog B (S. cerevisiae)
TSKU tsukushi, small leucine rich proteoglycan
TSN translin
TSPAN32 tetraspanin 32
TTC24 tetratricopeptide repeat domain 24
TTC5 tetratricopeptide repeat domain 5
TUFT1 tuftelin 1
UBAP1 ubiquitin associated protein 1
UBAP2 ubiquitin associated protein 2
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBE2R2 ubiquitin-conjugating enzyme E2R 2
USH1G Usher syndrome 1G (autosomal recessive)
USP11 ubiquitin specific peptidase 11
VCP valosin containing protein
WDFY1 WD repeat and FYVE domain containing 1
XAF1 XIAP associated factor 1
XIRP1 xin actin binding repeat containing 1
XPO1 exportin 1
XRN1 5'-3' exoribonuclease 1
ZAN zonadhesin (gene/pseudogene)
ZAR1L zygote arrest 1-like
ZBP1 Z-DNA binding protein 1
ZBTB5 zinc finger and BTB domain containing 5
ZC3HAV1L zinc finger CCCH-type, antiviral 1-like
ZCCHC7 zinc finger, CCHC domain containing 7
ZHX2 zinc fingers and homeoboxes 2
ZNF267 zinc finger protein 267
ZNF280C zinc finger protein 280C
ZNF343 zinc finger protein 343
ZNF48 zinc finger protein 48
ZNF646 zinc finger protein 646
ZNF683 zinc finger protein 683
ZNF689 zinc finger protein 689
ZNF747 zinc finger protein 747
ZNF843 zinc finger protein 843