Lung squamous cell carcinoma_LUSC_TCGA-92-7341-01A-31R-2045-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

412 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-92-7341-01A-31R-2045-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAK1 AP2 associated kinase 1
AARS alanyl-tRNA synthetase
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD15 abhydrolase domain containing 15
ABI2 abl-interactor 2
ACLY ATP citrate lyase
ACSF3 acyl-CoA synthetase family member 3
ACTL6A actin-like 6A
ACTR6 ARP6 actin-related protein 6 homolog (yeast)
ADAT1 adenosine deaminase, tRNA-specific 1
ADCY8 adenylate cyclase 8 (brain)
ADD2 adducin 2 (beta)
ADRA1D adrenoceptor alpha 1D
ADRA2C adrenoceptor alpha 2C
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANAPC1 anaphase promoting complex subunit 1
ANKRD31 ankyrin repeat domain 31
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ARHGAP28 Rho GTPase activating protein 28
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASPN asporin
ATMIN ATM interactor
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP5SL ATP5S-like
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BLVRA biliverdin reductase A
BLVRB biliverdin reductase B
BRD4 bromodomain containing 4
BTBD1 BTB (POZ) domain containing 1
BTBD11 BTB (POZ) domain containing 11
C16ORF70 chromosome 16 open reading frame 70
C16ORF87 chromosome 16 open reading frame 87
C17ORF105 chromosome 17 open reading frame 105
C2ORF69 chromosome 2 open reading frame 69
C4ORF27 chromosome 4 open reading frame 27
C9ORF64 chromosome 9 open reading frame 64
CALN1 calneuron 1
CASC4 cancer susceptibility candidate 4
CASC5 cancer susceptibility candidate 5
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CATSPER2P1 cation channel, sperm associated 2 pseudogene 1
CBR4 carbonyl reductase 4
CCDC177 coiled-coil domain containing 177
CCDC51 coiled-coil domain containing 51
CCDC97 coiled-coil domain containing 97
CCNA1 cyclin A1
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CD109 CD109 molecule
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH13 cadherin 13
CDK17 cyclin-dependent kinase 17
CDKN2AIP CDKN2A interacting protein
CDT1 chromatin licensing and DNA replication factor 1
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CENPBD1 CENPB DNA-binding domains containing 1
CENPH centromere protein H
CFAP97 cilia and flagella associated protein 97
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHD8 chromodomain helicase DNA binding protein 8
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
CIAPIN1 cytokine induced apoptosis inhibitor 1
CLASP1 cytoplasmic linker associated protein 1
CLCN3 chloride channel, voltage-sensitive 3
CLEC2L C-type lectin domain family 2, member L
CLIP2 CAP-GLY domain containing linker protein 2
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CMIP c-Maf inducing protein
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
CNOT1 CCR4-NOT transcription complex, subunit 1
CNTNAP2 contactin associated protein-like 2
COG8 component of oligomeric golgi complex 8
COPS2 COP9 signalosome subunit 2
CORO1C coronin, actin binding protein, 1C
COX8C cytochrome c oxidase subunit VIIIC
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPNE2 copine II
CPXM2 carboxypeptidase X (M14 family), member 2
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CREBBP CREB binding protein
CSNK1G1 casein kinase 1, gamma 1
CSNK2A2 casein kinase 2, alpha prime polypeptide
CYB5B cytochrome b5 type B (outer mitochondrial membrane)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCTD dCMP deaminase
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DEDD2 death effector domain containing 2
DENND4A DENN/MADD domain containing 4A
DGKG diacylglycerol kinase, gamma 90kDa
DHCR7 7-dehydrocholesterol reductase
DHODH dihydroorotate dehydrogenase (quinone)
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DPH6 diphthamine biosynthesis 6
DPP8 dipeptidyl-peptidase 8
DUSP19 dual specificity phosphatase 19
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHBP1 EH domain binding protein 1
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EIF3C eukaryotic translation initiation factor 3, subunit C
EIF3J eukaryotic translation initiation factor 3, subunit J
EPDR1 ependymin related 1
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
ETF1 eukaryotic translation termination factor 1
EXOC6B exocyst complex component 6B
EXOSC6 exosome component 6
F2RL1 coagulation factor II (thrombin) receptor-like 1
F2RL2 coagulation factor II (thrombin) receptor-like 2
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FAM192A family with sequence similarity 192, member A
FAM83D family with sequence similarity 83, member D
FAM86C1 family with sequence similarity 86, member C1
FBXO22 F-box protein 22
FER1L6 fer-1-like family member 6
FKBP10 FK506 binding protein 10, 65 kDa
FOXC2 forkhead box C2
FOXL1 forkhead box L1
FRMPD4 FERM and PDZ domain containing 4
FSTL5 follistatin-like 5
FTH1P3 ferritin, heavy polypeptide 1 pseudogene 3
FZD7 frizzled class receptor 7
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GALK2 galactokinase 2
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GAN gigaxonin
GARS glycyl-tRNA synthetase
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GATSL2 GATS protein-like 2
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GCSH glycine cleavage system protein H (aminomethyl carrier)
GDA guanine deaminase
GDAP1 ganglioside induced differentiation associated protein 1
GINS3 GINS complex subunit 3 (Psf3 homolog)
GLG1 golgi glycoprotein 1
GLRB glycine receptor, beta
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GNB5 guanine nucleotide binding protein (G protein), beta 5
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPI glucose-6-phosphate isomerase
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2
GSK3A glycogen synthase kinase 3 alpha
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HAS3 hyaluronan synthase 3
HAUS2 HAUS augmin-like complex, subunit 2
HCG4B HLA complex group 4B (non-protein coding)
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HHEX hematopoietically expressed homeobox
HK1 hexokinase 1
HMOX2 heme oxygenase 2
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HRNR hornerin
HSPA4 heat shock 70kDa protein 4
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HYAL3 hyaluronoglucosaminidase 3
IQCJ IQ motif containing J
IRF5 interferon regulatory factor 5
ITFG1 integrin alpha FG-GAP repeat containing 1
ITGA6 integrin, alpha 6
IWS1 IWS1 homolog (S. cerevisiae)
JADE2 jade family PHD finger 2
KANSL3 KAT8 regulatory NSL complex subunit 3
KCNG3 potassium channel, voltage gated modifier subfamily G, member 3
KCTD18 potassium channel tetramerization domain containing 18
KIAA1549 KIAA1549
KIAA1549L KIAA1549-like
KIAA1715 KIAA1715
KLHL34 kelch-like family member 34
KNSTRN kinetochore-localized astrin/SPAG5 binding protein
KRT32 keratin 32, type I
LAMB2P1 laminin, beta 2 pseudogene 1
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LMAN2L lectin, mannose-binding 2-like
LOC100133985 uncharacterized LOC100133985
LOC145783 uncharacterized LOC145783
LONP2 lon peptidase 2, peroxisomal
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRIF1 ligand dependent nuclear receptor interacting factor 1
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRTM1 leucine rich repeat transmembrane neuronal 1
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
MAGEB2 melanoma antigen family B2
MAGEB6 melanoma antigen family B6
MAGEF1 melanoma antigen family F1
MAML3 mastermind-like 3 (Drosophila)
MAP1A microtubule-associated protein 1A
MAP1B microtubule-associated protein 1B
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K5 mitogen-activated protein kinase kinase 5
MARVELD2 MARVEL domain containing 2
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MFAP1 microfibrillar-associated protein 1
MFAP3L microfibrillar-associated protein 3-like
MFN1 mitofusin 1
MFSD6 major facilitator superfamily domain containing 6
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MPHOSPH6 M-phase phosphoprotein 6
MPI mannose phosphate isomerase
MRPL47 mitochondrial ribosomal protein L47
MSC musculin
MSMO1 methylsterol monooxygenase 1
MTFMT mitochondrial methionyl-tRNA formyltransferase
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MTO1 mitochondrial tRNA translation optimization 1
MVD mevalonate (diphospho) decarboxylase
MYO5A myosin VA (heavy chain 12, myoxin)
NAE1 NEDD8 activating enzyme E1 subunit 1
NAF1 nuclear assembly factor 1 ribonucleoprotein
NDRG4 NDRG family member 4
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
NEK1 NIMA-related kinase 1
NELFCD negative elongation factor complex member C/D
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NF1 neurofibromin 1
NIP7 NIP7, nucleolar pre-rRNA processing protein
NLN neurolysin (metallopeptidase M3 family)
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
NOTCH3 notch 3
NPC1 Niemann-Pick disease, type C1
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NPTN neuroplastin
NRCAM neuronal cell adhesion molecule
NUDCD3 NudC domain containing 3
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21
NUP205 nucleoporin 205kDa
NUP35 nucleoporin 35kDa
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1
OR10H2 olfactory receptor, family 10, subfamily H, member 2
OR4F4 olfactory receptor, family 4, subfamily F, member 4
OSGIN1 oxidative stress induced growth inhibitor 1
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PAIP2 poly(A) binding protein interacting protein 2
PALLD palladin, cytoskeletal associated protein
PAPD5 PAP associated domain containing 5
PAQR3 progestin and adipoQ receptor family member III
PC pyruvate carboxylase
PCDHGB4 protocadherin gamma subfamily B, 4
PCDHGB6 protocadherin gamma subfamily B, 6
PDCD7 programmed cell death 7
PDF peptide deformylase (mitochondrial)
PDGFC platelet derived growth factor C
PDIA3 protein disulfide isomerase family A, member 3
PDIA3P1 protein disulfide isomerase family A, member 3 pseudogene 1
PDIA4 protein disulfide isomerase family A, member 4
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PELI2 pellino E3 ubiquitin protein ligase family member 2
PELO pelota homolog (Drosophila)
PGAP1 post-GPI attachment to proteins 1
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHKB phosphorylase kinase, beta
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PKN1 protein kinase N1
PNMAL1 paraneoplastic Ma antigen family-like 1
POLD2 polymerase (DNA directed), delta 2, accessory subunit
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
POU2F1 POU class 2 homeobox 1
PPID peptidylprolyl isomerase D
PPME1 protein phosphatase methylesterase 1
PRIMPOL primase and polymerase (DNA-directed)
PRR34 proline rich 34
PRSS21 protease, serine, 21 (testisin)
PSAT1 phosphoserine aminotransferase 1
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PTCD2 pentatricopeptide repeat domain 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PURB purine-rich element binding protein B
RAB3B RAB3B, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAD54L2 RAD54-like 2 (S. cerevisiae)
RFWD3 ring finger and WD repeat domain 3
RFX7 regulatory factor X, 7
RGMA repulsive guidance molecule family member a
RNF121 ring finger protein 121
RPAP1 RNA polymerase II associated protein 1
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
RWDD4 RWD domain containing 4
SAMD12 sterile alpha motif domain containing 12
SAMD4B sterile alpha motif domain containing 4B
SBNO1 strawberry notch homolog 1 (Drosophila)
SCARNA9L small Cajal body-specific RNA 9-like
SDK1 sidekick cell adhesion molecule 1
SEPT11 septin 11
SERINC5 serine incorporator 5
SFT2D3 SFT2 domain containing 3
SH2D5 SH2 domain containing 5
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHCBP1 SHC SH2-domain binding protein 1
SHISA2 shisa family member 2
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
SLC35E1 solute carrier family 35, member E1
SLC35E4 solute carrier family 35, member E4
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
SLC7A6OS solute carrier family 7, member 6 opposite strand
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SLURP1 secreted LY6/PLAUR domain containing 1
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SPIN2A spindlin family, member 2A
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SSTR4 somatostatin receptor 4
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STOX2 storkhead box 2
STRN3 striatin, calmodulin binding protein 3
SULF1 sulfatase 1
SULF2 sulfatase 2
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TBC1D22A TBC1 domain family, member 22A
TBL1X transducin (beta)-like 1X-linked
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TEX33 testis expressed 33
TGFB1 transforming growth factor, beta 1
TIPIN TIMELESS interacting protein
TLN2 talin 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM177 transmembrane protein 177
TMEM194B transmembrane protein 194B
TMEM206 transmembrane protein 206
TMEM41A transmembrane protein 41A
TNPO1 transportin 1
TOX4 TOX high mobility group box family member 4
TP53BP1 tumor protein p53 binding protein 1
TRAP1 TNF receptor-associated protein 1
TSHZ3 teashirt zinc finger homeobox 3
TSPAN18 tetraspanin 18
TTBK2 tau tubulin kinase 2
TUBGCP4 tubulin, gamma complex associated protein 4
TUBGCP5 tubulin, gamma complex associated protein 5
TUFT1 tuftelin 1
TYRO3 TYRO3 protein tyrosine kinase
UBA2 ubiquitin-like modifier activating enzyme 2
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE2H ubiquitin-conjugating enzyme E2H
UBN1 ubinuclein 1
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
UPK3BL uroplakin 3B-like
URI1 URI1, prefoldin-like chaperone
USP10 ubiquitin specific peptidase 10
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
USP8 ubiquitin specific peptidase 8
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VWA9 von Willebrand factor A domain containing 9
WBSCR16 Williams-Beuren syndrome chromosome region 16
WDR12 WD repeat domain 12
WDR62 WD repeat domain 62
WDR75 WD repeat domain 75
WNT11 wingless-type MMTV integration site family, member 11
XYLT1 xylosyltransferase I
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZC3H15 zinc finger CCCH-type containing 15
ZMAT3 zinc finger, matrin-type 3
ZMYND8 zinc finger, MYND-type containing 8
ZNF146 zinc finger protein 146
ZNF217 zinc finger protein 217
ZNF462 zinc finger protein 462
ZNF526 zinc finger protein 526
ZNF629 zinc finger protein 629
ZNF639 zinc finger protein 639
ZNF706 zinc finger protein 706
ZNF853 zinc finger protein 853

low expression

Symbol Name
AP4B1 adaptor-related protein complex 4, beta 1 subunit
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
RSBN1 round spermatid basic protein 1