Lung squamous cell carcinoma_LUSC_TCGA-92-7340-01A-21R-2045-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

393 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-92-7340-01A-21R-2045-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AASDH aminoadipate-semialdehyde dehydrogenase
ACSL1 acyl-CoA synthetase long-chain family member 1
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTL8 actin-like 8
ADAM12 ADAM metallopeptidase domain 12
ADAM20 ADAM metallopeptidase domain 20
ADAM21P1 ADAM metallopeptidase domain 21 pseudogene 1
ADGRG7 adhesion G protein-coupled receptor G7
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
AMACR alpha-methylacyl-CoA racemase
ANKRD17 ankyrin repeat domain 17
ANKRD32 ankyrin repeat domain 32
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APLNR apelin receptor
APOD apolipoprotein D
ARF6 ADP-ribosylation factor 6
ARHGAP5-AS1 ARHGAP5 antisense RNA 1 (head to head)
ARL2BP ADP-ribosylation factor-like 2 binding protein
ASCC2 activating signal cointegrator 1 complex subunit 2
ASPN asporin
ATF7IP activating transcription factor 7 interacting protein
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
BACE2 beta-site APP-cleaving enzyme 2
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BCAS4 breast carcinoma amplified sequence 4
BCKDK branched chain ketoacid dehydrogenase kinase
BGN biglycan
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BOLA2 bolA family member 2
BRWD1 bromodomain and WD repeat domain containing 1
BTG1 B-cell translocation gene 1, anti-proliferative
BZW1 basic leucine zipper and W2 domains 1
C14ORF1 chromosome 14 open reading frame 1
C14ORF166 chromosome 14 open reading frame 166
C14ORF37 chromosome 14 open reading frame 37
C17ORF100 chromosome 17 open reading frame 100
C19ORF70 chromosome 19 open reading frame 70
C1ORF186 chromosome 1 open reading frame 186
C1QTNF3 C1q and tumor necrosis factor related protein 3
C2ORF47 chromosome 2 open reading frame 47
C2ORF69 chromosome 2 open reading frame 69
C5ORF46 chromosome 5 open reading frame 46
CALD1 caldesmon 1
CARF calcium responsive transcription factor
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CATSPERB catsper channel auxiliary subunit beta
CCL11 chemokine (C-C motif) ligand 11
CCNG2 cyclin G2
CCNI cyclin I
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDKN2AIP CDKN2A interacting protein
CDNF cerebral dopamine neurotrophic factor
CDYL2 chromodomain protein, Y-like 2
CEACAM20 carcinoembryonic antigen-related cell adhesion molecule 20
CENPC centromere protein C
CENPU centromere protein U
CERCAM cerebral endothelial cell adhesion molecule
CFAP47 cilia and flagella associated protein 47
CFAP97 cilia and flagella associated protein 97
CFLAR CASP8 and FADD-like apoptosis regulator
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHRM5 cholinergic receptor, muscarinic 5
CHSY3 chondroitin sulfate synthase 3
CLDN1 claudin 1
CNOT6L CCR4-NOT transcription complex, subunit 6-like
CNPY4 canopy FGF signaling regulator 4
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COL12A1 collagen, type XII, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
COPZ2 coatomer protein complex, subunit zeta 2
CORIN corin, serine peptidase
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
COX18 COX18 cytochrome c oxidase assembly factor
CPNE8 copine VIII
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CSNK1A1L casein kinase 1, alpha 1-like
CTF1 cardiotrophin 1
CTHRC1 collagen triple helix repeat containing 1
CTNND1 catenin (cadherin-associated protein), delta 1
CTSK cathepsin K
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL6 chemokine (C-X-C motif) ligand 6
DCLK3 doublecortin-like kinase 3
DCLRE1C DNA cross-link repair 1C
DCTD dCMP deaminase
DEFB1 defensin, beta 1
DEFB126 defensin, beta 126
DESI2 desumoylating isopeptidase 2
DHRS7 dehydrogenase/reductase (SDR family) member 7
DICER1 dicer 1, ribonuclease type III
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DIRC1 disrupted in renal carcinoma 1
DLD dihydrolipoamide dehydrogenase
DLG3 discs, large homolog 3 (Drosophila)
DMRTA1 DMRT-like family A1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOPEY2 dopey family member 2
DPT dermatopontin
DSC2 desmocollin 2
DUSP18 dual specificity phosphatase 18
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EEA1 early endosome antigen 1
EFCAB11 EF-hand calcium binding domain 11
EIF5B eukaryotic translation initiation factor 5B
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EXD2 exonuclease 3'-5' domain containing 2
EXOC3-AS1 EXOC3 antisense RNA 1
FAIM Fas apoptotic inhibitory molecule
FAM117B family with sequence similarity 117, member B
FAM126B family with sequence similarity 126, member B
FAM131C family with sequence similarity 131, member C
FAM185A family with sequence similarity 185, member A
FAM198B family with sequence similarity 198, member B
FAM227B family with sequence similarity 227, member B
FAM27C family with sequence similarity 27, member C
FAP fibroblast activation protein, alpha
FBN1 fibrillin 1
FBXO34 F-box protein 34
FCF1 FCF1 rRNA-processing protein
FKBP7 FK506 binding protein 7
FLJ30679 uncharacterized protein FLJ30679
FNDC1 fibronectin type III domain containing 1
FOXS1 forkhead box S1
FRG1 FSHD region gene 1
FRMD6 FERM domain containing 6
FSTL1 follistatin-like 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GABPB2 GA binding protein transcription factor, beta subunit 2
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GAS2L1 growth arrest-specific 2 like 1
GBA glucosidase, beta, acid
GBAP1 glucosidase, beta, acid pseudogene 1
GCH1 GTP cyclohydrolase 1
GGCX gamma-glutamyl carboxylase
GLMP glycosylated lysosomal membrane protein
GLT8D2 glycosyltransferase 8 domain containing 2
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GPR85 G protein-coupled receptor 85
HEATR6 HEAT repeat containing 6
HEPH hephaestin
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H2AM histone cluster 1, H2am
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMGN1 high mobility group nucleosome binding domain 1
HTRA1 HtrA serine peptidase 1
HTRA3 HtrA serine peptidase 3
IFNAR1 interferon (alpha, beta and omega) receptor 1
IKBIP IKBKB interacting protein
IL10RB interleukin 10 receptor, beta
IL31 interleukin 31
ING2 inhibitor of growth family, member 2
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
INTS9 integrator complex subunit 9
IQCF6 IQ motif containing F6
IRF2 interferon regulatory factor 2
ISM1 isthmin 1, angiogenesis inhibitor
ITGA11 integrin, alpha 11
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCTD18 potassium channel tetramerization domain containing 18
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIAA0391 KIAA0391
KIAA1551 KIAA1551
KIF5B kinesin family member 5B
KITLG KIT ligand
KLHL28 kelch-like family member 28
KRTAP17-1 keratin associated protein 17-1
KRTAP4-1 keratin associated protein 4-1
KRTCAP2 keratinocyte associated protein 2
LCA5L Leber congenital amaurosis 5-like
LINC00111 long intergenic non-protein coding RNA 111
LINC01547 long intergenic non-protein coding RNA 1547
LINC01559 long intergenic non-protein coding RNA 1559
LOC100132831 A20-binding inhibitor of NF-kappaB activation 2 pseudogene
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3
LRRC15 leucine rich repeat containing 15
LTN1 listerin E3 ubiquitin protein ligase 1
LY6D lymphocyte antigen 6 complex, locus D
MARCKS myristoylated alanine-rich protein kinase C substrate
MAX MYC associated factor X
MED6 mediator complex subunit 6
METTL21C methyltransferase like 21C
MFAP5 microfibrillar associated protein 5
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MIS18A MIS18 kinetochore protein A
MKRN1 makorin ring finger protein 1
MMP2 matrix metallopeptidase 2
MORC3 MORC family CW-type zinc finger 3
MOSPD3 motile sperm domain containing 3
MRPL1 mitochondrial ribosomal protein L1
MRPS33 mitochondrial ribosomal protein S33
MRVI1 murine retrovirus integration site 1 homolog
MTAP methylthioadenosine phosphorylase
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MX1 MX dynamin-like GTPase 1
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NBEAL1 neurobeachin-like 1
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
NET1 neuroepithelial cell transforming 1
NF2 neurofibromin 2 (merlin)
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
NMT2 N-myristoyltransferase 2
NOA1 nitric oxide associated 1
NOP58 NOP58 ribonucleoprotein
NOX4 NADPH oxidase 4
NRTN neurturin
NUP54 nucleoporin 54kDa
OMD osteomodulin
ORAI3 ORAI calcium release-activated calcium modulator 3
ORC2 origin recognition complex, subunit 2
OSBPL8 oxysterol binding protein-like 8
P3H1 prolyl 3-hydroxylase 1
PAPOLA poly(A) polymerase alpha
PCDHA5 protocadherin alpha 5
PCDHB11 protocadherin beta 11
PCDHB14 protocadherin beta 14
PCDHB5 protocadherin beta 5
PDE9A phosphodiesterase 9A
PDGFRL platelet-derived growth factor receptor-like
PDLIM3 PDZ and LIM domain 3
PEX13 peroxisomal biogenesis factor 13
PHYH phytanoyl-CoA 2-hydroxylase
PIGP phosphatidylinositol glycan anchor biosynthesis, class P
PITRM1 pitrilysin metallopeptidase 1
PKNOX1 PBX/knotted 1 homeobox 1
PLA2G5 phospholipase A2, group V
PLAC1 placenta-specific 1
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
POSTN periostin, osteoblast specific factor
POTED POTE ankyrin domain family, member D
PPAP2C phosphatidic acid phosphatase type 2C
PPAPDC1A phosphatidic acid phosphatase type 2 domain containing 1A
PPIL3 peptidylprolyl isomerase (cyclophilin)-like 3
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPP4C protein phosphatase 4, catalytic subunit
PRIMPOL primase and polymerase (DNA-directed)
PRKCH protein kinase C, eta
PRMT2 protein arginine methyltransferase 2
PRPF18 pre-mRNA processing factor 18
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PRR16 proline rich 16
PSEN1 presenilin 1
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTTG1IP pituitary tumor-transforming 1 interacting protein
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RHCE Rh blood group, CcEe antigens
RIPK4 receptor-interacting serine-threonine kinase 4
RNASE10 ribonuclease, RNase A family, 10 (non-active)
RNASEK ribonuclease, RNase K
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF185 ring finger protein 185
RPL13AP6 ribosomal protein L13a pseudogene 6
RPS4X ribosomal protein S4, X-linked
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRP1B ribosomal RNA processing 1B
RSRC1 arginine/serine-rich coiled-coil 1
RUNX1 runt-related transcription factor 1
RWDD2B RWD domain containing 2B
RWDD4 RWD domain containing 4
S100A11 S100 calcium binding protein A11
S100A2 S100 calcium binding protein A2
SCARB2 scavenger receptor class B, member 2
SCT secretin
SDAD1 SDA1 domain containing 1
SEC23A Sec23 homolog A (S. cerevisiae)
SEPT11 septin 11
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP2 secreted frizzled-related protein 2
SFRP4 secreted frizzled-related protein 4
SGOL2 shugoshin-like 2 (S. pombe)
SHBG sex hormone-binding globulin
SHOX2 short stature homeobox 2
SIX1 SIX homeobox 1
SLC22A20 solute carrier family 22, member 20
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC37A3 solute carrier family 37, member 3
SLED1 proteoglycan 3 pseudogene
SMCO1 single-pass membrane protein with coiled-coil domains 1
SMCP sperm mitochondria-associated cysteine-rich protein
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SNORA11D small nucleolar RNA, H/ACA box 11D
SNORA2A small nucleolar RNA, H/ACA box 2A
SNORA47 small nucleolar RNA, H/ACA box 47
SNORA61 small nucleolar RNA, H/ACA box 61
SNORA65 small nucleolar RNA, H/ACA box 65
SNORA67 small nucleolar RNA, H/ACA box 67
SOCS2 suppressor of cytokine signaling 2
SON SON DNA binding protein
SOS2 son of sevenless homolog 2 (Drosophila)
SOWAHB sosondowah ankyrin repeat domain family member B
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPATS2L spermatogenesis associated, serine-rich 2-like
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SRP54 signal recognition particle 54kDa
SSPN sarcospan
SSR4P1 signal sequence receptor, delta pseudogene 1
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
ST7-AS1 ST7 antisense RNA 1
ST7L suppression of tumorigenicity 7 like
STK17B serine/threonine kinase 17b
STON2 stonin 2
STOX2 storkhead box 2
STYX serine/threonine/tyrosine interacting protein
SULF1 sulfatase 1
SUMO1 small ubiquitin-like modifier 1
SUMO1P3 SUMO1 pseudogene 3 (functional)
SUMO3 small ubiquitin-like modifier 3
SYCE1 synaptonemal complex central element protein 1
SYPL1 synaptophysin-like 1
TAGLN transgelin
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TBX15 T-box 15
TBX6 T-box 6
TC2N tandem C2 domains, nuclear
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB3 transforming growth factor, beta 3
THAP6 THAP domain containing 6
THBD thrombomodulin
THBS2 thrombospondin 2
THEG theg spermatid protein
THY1 Thy-1 cell surface antigen
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMP2 TIMP metallopeptidase inhibitor 2
TMEM135 transmembrane protein 135
TMEM156 transmembrane protein 156
TMEM168 transmembrane protein 168
TMEM237 transmembrane protein 237
TMEM30B transmembrane protein 30B
TMEM65 transmembrane protein 65
TMEM99 transmembrane protein 99
TMPRSS11D transmembrane protease, serine 11D
TMPRSS12 transmembrane (C-terminal) protease, serine 12
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNNI1 troponin I type 1 (skeletal, slow)
TRAPPC1 trafficking protein particle complex 1
TRAPPC10 trafficking protein particle complex 10
TRAPPC11 trafficking protein particle complex 11
TRIM59 tripartite motif containing 59
TRIP11 thyroid hormone receptor interactor 11
TTC26 tetratricopeptide repeat domain 26
TTC3 tetratricopeptide repeat domain 3
TUG1 taurine up-regulated 1 (non-protein coding)
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBQLN2 ubiquilin 2
UFSP2 UFM1-specific peptidase 2
UNCX UNC homeobox
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
URB1-AS1 URB1 antisense RNA 1 (head to head)
USO1 USO1 vesicle transport factor
VCAN versican
VTI1B vesicle transport through interaction with t-SNAREs 1B
WDR12 WD repeat domain 12
WNT2 wingless-type MMTV integration site family member 2
WNT2B wingless-type MMTV integration site family, member 2B
WRB tryptophan rich basic protein
YBEY ybeY metallopeptidase (putative)
YME1L1 YME1-like 1 ATPase
ZBTB21 zinc finger and BTB domain containing 21
ZCCHC5 zinc finger, CCHC domain containing 5
ZFP90 ZFP90 zinc finger protein
ZFYVE1 zinc finger, FYVE domain containing 1
ZMAT5 zinc finger, matrin-type 5
ZNF267 zinc finger protein 267
ZNF277 zinc finger protein 277
ZNF624 zinc finger protein 624
ZNF720 zinc finger protein 720

low expression

Symbol Name
AP3M1 adaptor-related protein complex 3, mu 1 subunit