Lung squamous cell carcinoma_LUSC_TCGA-90-7964-01A-21R-2187-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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380 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-90-7964-01A-21R-2187-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABHD2 abhydrolase domain containing 2
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ADAM15 ADAM metallopeptidase domain 15
ADCK3 aarF domain containing kinase 3
ADPRHL2 ADP-ribosylhydrolase like 2
ADSSL1 adenylosuccinate synthase like 1
AGBL3 ATP/GTP binding protein-like 3
AGFG1 ArfGAP with FG repeats 1
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AHCYL1 adenosylhomocysteinase-like 1
AHDC1 AT hook, DNA binding motif, containing 1
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AKR1C6P aldo-keto reductase family 1, member C6, pseudogene
AMN amnion associated transmembrane protein
ANKHD1 ankyrin repeat and KH domain containing 1
ANKRD9 ankyrin repeat domain 9
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
AR androgen receptor
ARHGAP35 Rho GTPase activating protein 35
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARRDC5 arrestin domain containing 5
ARSA arylsulfatase A
ASIC5 acid sensing (proton gated) ion channel family member 5
ASPH aspartate beta-hydroxylase
ATP13A2 ATPase type 13A2
AVPI1 arginine vasopressin-induced 1
BACE2 beta-site APP-cleaving enzyme 2
BMP10 bone morphogenetic protein 10
BPY2 basic charge, Y-linked, 2
BRD8 bromodomain containing 8
BSDC1 BSD domain containing 1
BTBD8 BTB (POZ) domain containing 8
C11ORF53 chromosome 11 open reading frame 53
C12ORF74 chromosome 12 open reading frame 74
C14ORF178 chromosome 14 open reading frame 178
C16ORF13 chromosome 16 open reading frame 13
C17ORF77 chromosome 17 open reading frame 77
C1ORF106 chromosome 1 open reading frame 106
C1ORF168 chromosome 1 open reading frame 168
C1ORF228 chromosome 1 open reading frame 228
C1ORF86 chromosome 1 open reading frame 86
C2CD2 C2 calcium-dependent domain containing 2
C2CD4D C2 calcium-dependent domain containing 4D
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAGE1 cancer antigen 1
CAPN12 calpain 12
CBR3 carbonyl reductase 3
CC2D1B coiled-coil and C2 domain containing 1B
CCDC129 coiled-coil domain containing 129
CCDC6 coiled-coil domain containing 6
CCDC61 coiled-coil domain containing 61
CCDC64 coiled-coil domain containing 64
CD151 CD151 molecule (Raph blood group)
CDC23 cell division cycle 23
CDC25C cell division cycle 25C
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CES1 carboxylesterase 1
CHODL-AS1 CHODL antisense RNA 1
CLC Charcot-Leyden crystal galectin
CLCC1 chloride channel CLIC-like 1
CLCN1 chloride channel, voltage-sensitive 1
CLDN3 claudin 3
CLN3 ceroid-lipofuscinosis, neuronal 3
CLPSL1 colipase-like 1
CLPSL2 colipase-like 2
CLU clusterin
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COLCA1 colorectal cancer associated 1
COLCA2 colorectal cancer associated 2
CPPED1 calcineurin-like phosphoesterase domain containing 1
CPSF3L cleavage and polyadenylation specific factor 3-like
CPT2 carnitine palmitoyltransferase 2
CPTP ceramide-1-phosphate transfer protein
CRACR2B calcium release activated channel regulator 2B
CSDE1 cold shock domain containing E1, RNA-binding
CSMD1 CUB and Sushi multiple domains 1
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTSC cathepsin C
CXXC5 CXXC finger protein 5
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYSTM1 cysteine-rich transmembrane module containing 1
DCPS decapping enzyme, scavenger
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DEFB131 defensin, beta 131
DET1 de-etiolated homolog 1 (Arabidopsis)
DHRS3 dehydrogenase/reductase (SDR family) member 3
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DIS3L DIS3 like exosome 3'-5' exoribonuclease
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DND1 DND microRNA-mediated repression inhibitor 1
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
DOCK5 dedicator of cytokinesis 5
DOPEY2 dopey family member 2
DPRXP4 divergent-paired related homeobox pseudogene 4
DUSP23 dual specificity phosphatase 23
DUSP5 dual specificity phosphatase 5
DVL1 dishevelled segment polarity protein 1
EGF epidermal growth factor
EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELMO3 engulfment and cell motility 3
EMB embigin
EPHB2 EPH receptor B2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB3 erb-b2 receptor tyrosine kinase 3
ERCC2 excision repair cross-complementation group 2
ERN2 endoplasmic reticulum to nucleus signaling 2
ETF1 eukaryotic translation termination factor 1
ETNPPL ethanolamine-phosphate phospho-lyase
EVA1C eva-1 homolog C (C. elegans)
EXOSC10 exosome component 10
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM107B family with sequence similarity 107, member B
FAM131B family with sequence similarity 131, member B
FAM13A-AS1 FAM13A antisense RNA 1
FAM213B family with sequence similarity 213, member B
FAM53C family with sequence similarity 53, member C
FAM71D family with sequence similarity 71, member D
FAM73A family with sequence similarity 73, member A
FAM86B1 family with sequence similarity 86, member B1
FAM86B2 family with sequence similarity 86, member B2
FBXL8 F-box and leucine-rich repeat protein 8
FKBP1AP1 FK506 binding protein 1A, 12kDa pseudogene 1
FKRP fukutin related protein
FTH1P3 ferritin, heavy polypeptide 1 pseudogene 3
FTL ferritin, light polypeptide
FUT2 fucosyltransferase 2 (secretor status included)
G6PD glucose-6-phosphate dehydrogenase
GADD45A growth arrest and DNA-damage-inducible, alpha
GALE UDP-galactose-4-epimerase
GCLM glutamate-cysteine ligase, modifier subunit
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GEMIN8P4 gem (nuclear organelle) associated protein 8 pseudogene 4
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPN2 GPN-loop GTPase 2
GRXCR2 glutaredoxin, cysteine rich 2
GSR glutathione reductase
GSTA3 glutathione S-transferase alpha 3
GSTM4 glutathione S-transferase mu 4
GSTT1 glutathione S-transferase theta 1
GUCY2EP guanylate cyclase 2E, pseudogene
HAGHL hydroxyacylglutathione hydrolase-like
HARS histidyl-tRNA synthetase
HARS2 histidyl-tRNA synthetase 2, mitochondrial
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HES1 hes family bHLH transcription factor 1
HHIPL2 HHIP-like 2
HHLA3 HERV-H LTR-associating 3
HKDC1 hexokinase domain containing 1
HOXA5 homeobox A5
HOXA6 homeobox A6
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13
HSP90AB4P heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene
HSPA12A heat shock 70kDa protein 12A
HSPA9 heat shock 70kDa protein 9 (mortalin)
HYI hydroxypyruvate isomerase (putative)
IDUA iduronidase, alpha-L-
IK IK cytokine, down-regulator of HLA II
IL25 interleukin 25
INADL InaD-like (Drosophila)
INAFM1 InaF-motif containing 1
IP6K3 inositol hexakisphosphate kinase 3
IRX3 iroquois homeobox 3
JAKMIP3 Janus kinase and microtubule interacting protein 3
KAZN kazrin, periplakin interacting protein
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDM5D lysine (K)-specific demethylase 5D
KIAA1107 KIAA1107
KIAA1147 KIAA1147
KIAA1522 KIAA1522
KIAA2013 KIAA2013
KIF20A kinesin family member 20A
KLHDC7A kelch domain containing 7A
KLHL17 kelch-like family member 17
KPNA6 karyopherin alpha 6 (importin alpha 7)
KRT7 keratin 7, type II
KRTAP5-9 keratin associated protein 5-9
KYNU kynureninase
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LGALS8 lectin, galactoside-binding, soluble, 8
LHFPL5 lipoma HMGIC fusion partner-like 5
LIME1 Lck interacting transmembrane adaptor 1
LINC01554 long intergenic non-protein coding RNA 1554
LINGO4 leucine rich repeat and Ig domain containing 4
LMTK3 lemur tyrosine kinase 3
LOC388242 coiled-coil domain containing 101 pseudogene
LOC644172 mitogen-activated protein kinase 8 interacting protein 1 pseudogene
LONP2 lon peptidase 2, peroxisomal
LPP LIM domain containing preferred translocation partner in lipoma
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRP1B low density lipoprotein receptor-related protein 1B
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC37A leucine rich repeat containing 37A
LRRC37A2 leucine rich repeat containing 37, member A2
LRRC39 leucine rich repeat containing 39
LRRC41 leucine rich repeat containing 41
LYPLA2 lysophospholipase II
MAP10 microtubule-associated protein 10
MAP2 microtubule-associated protein 2
MAPK12 mitogen-activated protein kinase 12
MATR3 matrin 3
MBOAT7 membrane bound O-acyltransferase domain containing 7
MED25 mediator complex subunit 25
MFF mitochondrial fission factor
MKNK1 MAP kinase interacting serine/threonine kinase 1
MOV10 Mov10 RISC complex RNA helicase
MPL MPL proto-oncogene, thrombopoietin receptor
MRS2P2 MRS2 pseudogene 2
MVP major vault protein
MYH14 myosin, heavy chain 14, non-muscle
MZF1 myeloid zinc finger 1
NADK NAD kinase
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NEK8 NIMA-related kinase 8
NFIA nuclear factor I/A
NLGN4Y neuroligin 4, Y-linked
NLRP2 NLR family, pyrin domain containing 2
NME3 NME/NM23 nucleoside diphosphate kinase 3
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOL9 nucleolar protein 9
NQO1 NAD(P)H dehydrogenase, quinone 1
NR0B1 nuclear receptor subfamily 0, group B, member 1
NRD1 nardilysin (N-arginine dibasic convertase)
NSMCE1 non-SMC element 1 homolog (S. cerevisiae)
NSUN4 NOP2/Sun domain family, member 4
NTNG2 netrin G2
ODF2L outer dense fiber of sperm tails 2-like
OOEP oocyte expressed protein
OPN3 opsin 3
OR2AE1 olfactory receptor, family 2, subfamily AE, member 1
OR5A2 olfactory receptor, family 5, subfamily A, member 2
OSBPL9 oxysterol binding protein-like 9
OSGIN1 oxidative stress induced growth inhibitor 1
PANX2 pannexin 2
PAQR7 progestin and adipoQ receptor family member VII
PARP8 poly (ADP-ribose) polymerase family, member 8
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHGB6 protocadherin gamma subfamily B, 6
PCED1B PC-esterase domain containing 1B
PCNXL2 pecanex-like 2 (Drosophila)
PCP4L1 Purkinje cell protein 4 like 1
PERM1 PPARGC1 and ESRR induced regulator, muscle 1
PEX14 peroxisomal biogenesis factor 14
PFDN1 prefoldin subunit 1
PGBD2 piggyBac transposable element derived 2
PGD phosphogluconate dehydrogenase
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PKM pyruvate kinase, muscle
PLB1 phospholipase B1
PLD4 phospholipase D family, member 4
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7
PLEKHN1 pleckstrin homology domain containing, family N member 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLK2 polo-like kinase 2
PNPLA2 patatin-like phospholipase domain containing 2
POU2AF1 POU class 2 associating factor 1
POU2F1 POU class 2 homeobox 1
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PQLC2 PQ loop repeat containing 2
PRDX1 peroxiredoxin 1
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKY protein kinase, Y-linked, pseudogene
PRR12 proline rich 12
PRSS42 protease, serine, 42
PTPRF protein tyrosine phosphatase, receptor type, F
PUM1 pumilio RNA-binding family member 1
PURA purine-rich element binding protein A
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RAP1GAP RAP1 GTPase activating protein
RBBP6 retinoblastoma binding protein 6
RBM15 RNA binding motif protein 15
RCC1 regulator of chromosome condensation 1
RHBDL2 rhomboid, veinlet-like 2 (Drosophila)
RNASET2 ribonuclease T2
RNF24 ring finger protein 24
RNPEP arginyl aminopeptidase (aminopeptidase B)
RORC RAR-related orphan receptor C
RP1L1 retinitis pigmentosa 1-like 1
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RSC1A1 regulatory solute carrier protein, family 1, member 1
SAMD5 sterile alpha motif domain containing 5
SCAF1 SR-related CTD-associated factor 1
SCARA3 scavenger receptor class A, member 3
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SH2D7 SH2 domain containing 7
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIK1 salt-inducible kinase 1
SIL1 SIL1 nucleotide exchange factor
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC22A25 solute carrier family 22, member 25
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SLC35A4 solute carrier family 35, member A4
SLC35E2 solute carrier family 35, member E2
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC44A4 solute carrier family 44, member 4
SMOC1 SPARC related modular calcium binding 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNHG4 small nucleolar RNA host gene 4
SNORA16B small nucleolar RNA, H/ACA box 16B
SNORA29 small nucleolar RNA, H/ACA box 29
SNORA72 small nucleolar RNA, H/ACA box 72
SOD1 superoxide dismutase 1, soluble
SORD sorbitol dehydrogenase
SPDYE2 speedy/RINGO cell cycle regulator family member E2
SPHK2 sphingosine kinase 2
SPSB2 splA/ryanodine receptor domain and SOCS box containing 2
SRA1 steroid receptor RNA activator 1
SSH3 slingshot protein phosphatase 3
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STXBP3 syntaxin binding protein 3
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYCE3 synaptonemal complex central element protein 3
SYT12 synaptotagmin XII
SYTL1 synaptotagmin-like 1
TBL1Y transducin (beta)-like 1, Y-linked
TBXAS1 thromboxane A synthase 1 (platelet)
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
TEPP testis, prostate and placenta expressed
TEX38 testis expressed 38
THRAP3 thyroid hormone receptor associated protein 3
TLE3 transducin-like enhancer of split 3
TM7SF2 transmembrane 7 superfamily member 2
TMC4 transmembrane channel-like 4
TMCO5A transmembrane and coiled-coil domains 5A
TMCO6 transmembrane and coiled-coil domains 6
TMEM252 transmembrane protein 252
TMEM69 transmembrane protein 69
TMEM91 transmembrane protein 91
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIB2 tribbles pseudokinase 2
TRIM33 tripartite motif containing 33
TSEN34 TSEN34 tRNA splicing endonuclease subunit
TSKU tsukushi, small leucine rich proteoglycan
TSPAN1 tetraspanin 1
TSPAN7 tetraspanin 7
TTTY14 testis-specific transcript, Y-linked 14 (non-protein coding)
TTTY15 testis-specific transcript, Y-linked 15 (non-protein coding)
TTTY2 testis-specific transcript, Y-linked 2 (non-protein coding)
TUSC3 tumor suppressor candidate 3
TXLNGY taxilin gamma pseudogene, Y-linked
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBIAD1 UbiA prenyltransferase domain containing 1
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UNC93B1 unc-93 homolog B1 (C. elegans)
USP9Y ubiquitin specific peptidase 9, Y-linked
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
VAV3 vav 3 guanine nucleotide exchange factor
VRK3 vaccinia related kinase 3
WASF2 WAS protein family, member 2
WDR55 WD repeat domain 55
YBEY ybeY metallopeptidase (putative)
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2
ZBTB45 zinc finger and BTB domain containing 45
ZBTB48 zinc finger and BTB domain containing 48
ZDHHC18 zinc finger, DHHC-type containing 18
ZMAT2 zinc finger, matrin-type 2
ZNF296 zinc finger protein 296
ZNF362 zinc finger protein 362
ZNF446 zinc finger protein 446
ZNF552 zinc finger protein 552
ZNF628 zinc finger protein 628

low expression

Symbol Name
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit