Lung squamous cell carcinoma_LUSC_TCGA-85-8355-01A-11R-2296-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

416 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-85-8355-01A-11R-2296-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AAK1 AP2 associated kinase 1
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ACP5 acid phosphatase 5, tartrate resistant
ACSM5 acyl-CoA synthetase medium-chain family member 5
ADAMDEC1 ADAM-like, decysin 1
ADGRE2 adhesion G protein-coupled receptor E2
ADGRE4P adhesion G protein-coupled receptor E4, pseudogene
ADIPOQ adiponectin, C1Q and collagen domain containing
AKNA AT-hook transcription factor
ALDH1L2 aldehyde dehydrogenase 1 family, member L2
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ALS2CR11 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11
ANKRD44 ankyrin repeat domain 44
ANKRD55 ankyrin repeat domain 55
AOX2P aldehyde oxidase 2 pseudogene
ARHGAP15 Rho GTPase activating protein 15
ARHGAP25 Rho GTPase activating protein 25
ARHGAP30 Rho GTPase activating protein 30
ARHGAP5 Rho GTPase activating protein 5
ARID4A AT rich interactive domain 4A (RBP1-like)
ASXL2 additional sex combs like transcriptional regulator 2
ATF7IP activating transcription factor 7 interacting protein
ATM ATM serine/threonine kinase
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCORP1 BCL6 corepressor pseudogene 1
BEST1 bestrophin 1
BIN2 bridging integrator 2
BLK BLK proto-oncogene, Src family tyrosine kinase
BMP2K BMP2 inducible kinase
BOD1L1 biorientation of chromosomes in cell division 1-like 1
BPIFA1 BPI fold containing family A, member 1
BTLA B and T lymphocyte associated
C11ORF21 chromosome 11 open reading frame 21
C16ORF54 chromosome 16 open reading frame 54
C9ORF139 chromosome 9 open reading frame 139
CA1 carbonic anhydrase I
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC134 coiled-coil domain containing 134
CCL21 chemokine (C-C motif) ligand 21
CCL24 chemokine (C-C motif) ligand 24
CCP110 centriolar coiled coil protein 110kDa
CCR4 chemokine (C-C motif) receptor 4
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CCR8 chemokine (C-C motif) receptor 8
CD1B CD1b molecule
CD209 CD209 molecule
CD226 CD226 molecule
CD247 CD247 molecule
CD27 CD27 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD37 CD37 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD40LG CD40 ligand
CD5 CD5 molecule
CD6 CD6 molecule
CD72 CD72 molecule
CD84 CD84 molecule
CD96 CD96 molecule
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CECR1 cat eye syndrome chromosome region, candidate 1
CECR2 cat eye syndrome chromosome region, candidate 2
CEP85L centrosomal protein 85kDa-like
CETP cholesteryl ester transfer protein, plasma
CFP complement factor properdin
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHIT1 chitinase 1 (chitotriosidase)
CLEC10A C-type lectin domain family 10, member A
CLEC17A C-type lectin domain family 17, member A
CLEC4C C-type lectin domain family 4, member C
CLEC4E C-type lectin domain family 4, member E
CLEC4G C-type lectin domain family 4, member G
CLEC4GP1 C-type lectin domain family 4, member G pseudogene 1
CLEC4M C-type lectin domain family 4, member M
CLGN calmegin
CLIP1 CAP-GLY domain containing linker protein 1
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLNK cytokine-dependent hematopoietic cell linker
CMKLR1 chemerin chemokine-like receptor 1
CNOT6L CCR4-NOT transcription complex, subunit 6-like
CNR2 cannabinoid receptor 2 (macrophage)
CPEB3 cytoplasmic polyadenylation element binding protein 3
CPT2 carnitine palmitoyltransferase 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CSF1R colony stimulating factor 1 receptor
CTH cystathionine gamma-lyase
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSS cathepsin S
CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR5 chemokine (C-X-C motif) receptor 5
CYTIP cytohesin 1 interacting protein
DCANP1 dendritic cell-associated nuclear protein
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DENND1C DENN/MADD domain containing 1C
DHRS4 dehydrogenase/reductase (SDR family) member 4
DHRS4L1 dehydrogenase/reductase (SDR family) member 4 like 1
DHRS4L2 dehydrogenase/reductase (SDR family) member 4 like 2
DNAH1 dynein, axonemal, heavy chain 1
DNASE2B deoxyribonuclease II beta
DOCK10 dedicator of cytokinesis 10
DOCK2 dedicator of cytokinesis 2
DOCK8 dedicator of cytokinesis 8
DUPD1 dual specificity phosphatase and pro isomerase domain containing 1
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EBF3 early B-cell factor 3
ECH1 enoyl CoA hydratase 1, peroxisomal
EPB41 erythrocyte membrane protein band 4.1
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR2 estrogen receptor 2 (ER beta)
EVI2B ecotropic viral integration site 2B
EVL Enah/Vasp-like
EXOC6B exocyst complex component 6B
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM102A family with sequence similarity 102, member A
FAM117B family with sequence similarity 117, member B
FAM126B family with sequence similarity 126, member B
FAM129A family with sequence similarity 129, member A
FAM135A family with sequence similarity 135, member A
FAM159A family with sequence similarity 159, member A
FAM180B family with sequence similarity 180, member B
FAM184B family with sequence similarity 184, member B
FAM21C family with sequence similarity 21, member C
FAM43A family with sequence similarity 43, member A
FAM49A family with sequence similarity 49, member A
FAM65B family with sequence similarity 65, member B
FAM78A family with sequence similarity 78, member A
FANCE Fanconi anemia, complementation group E
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXO27 F-box protein 27
FCMR Fc fragment of IgM receptor
FCRL3 Fc receptor-like 3
FERMT3 fermitin family member 3
FGD2 FYVE, RhoGEF and PH domain containing 2
FGD3 FYVE, RhoGEF and PH domain containing 3
FGF23 fibroblast growth factor 23
FGL2 fibrinogen-like 2
FLJ42627 uncharacterized LOC645644
FLT3 fms-related tyrosine kinase 3
FNBP1 formin binding protein 1
FOXD4L6 forkhead box D4-like 6
FOXO3 forkhead box O3
FOXO3B forkhead box O3B pseudogene
FOXP3 forkhead box P3
FUCA1 fucosidase, alpha-L- 1, tissue
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FXR1 fragile X mental retardation, autosomal homolog 1
FZD10 frizzled class receptor 10
FZD7 frizzled class receptor 7
GFOD1 glucose-fructose oxidoreductase domain containing 1
GLI1 GLI family zinc finger 1
GM2A GM2 ganglioside activator
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPATCH8 G patch domain containing 8
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR1 G protein-coupled receptor 1
GPR132 G protein-coupled receptor 132
GPR171 G protein-coupled receptor 171
GPR174 G protein-coupled receptor 174
GPR182 G protein-coupled receptor 182
GPR55 G protein-coupled receptor 55
GPRIN3 GPRIN family member 3
GRAP2 GRB2-related adaptor protein 2
GVINP1 GTPase, very large interferon inducible pseudogene 1
HEATR5A HEAT repeat containing 5A
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMHA1 histocompatibility (minor) HA-1
HPSE heparanase
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HSF5 heat shock transcription factor family member 5
ICOS inducible T-cell co-stimulator
IGF2R insulin-like growth factor 2 receptor
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10RA interleukin 10 receptor, alpha
IL12B interleukin 12B
IL16 interleukin 16
IL18BP interleukin 18 binding protein
IL7R interleukin 7 receptor
IL9R interleukin 9 receptor
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IPCEF1 interaction protein for cytohesin exchange factors 1
IPMK inositol polyphosphate multikinase
IQGAP2 IQ motif containing GTPase activating protein 2
IRF4 interferon regulatory factor 4
IRF8 interferon regulatory factor 8
ITGAD integrin, alpha D
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITK IL2-inducible T-cell kinase
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KIAA0125 KIAA0125
KIAA1551 KIAA1551
KIF21B kinesin family member 21B
KLHL6 kelch-like family member 6
KMT2C lysine (K)-specific methyltransferase 2C
KRTAP6-3 keratin associated protein 6-3
LAX1 lymphocyte transmembrane adaptor 1
LDHC lactate dehydrogenase C
LGALS2 lectin, galactoside-binding, soluble, 2
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LIPA lipase A, lysosomal acid, cholesterol esterase
LOC100128542
LOC653786 otoancorin pseudogene
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LTF lactotransferrin
LY9 lymphocyte antigen 9
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAP7D2 MAP7 domain containing 2
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha)
MDN1 MDN1, midasin homolog (yeast)
MERTK MER proto-oncogene, tyrosine kinase
METTL4 methyltransferase like 4
MFN1 mitofusin 1
MPEG1 macrophage expressed 1
MTCL1 microtubule crosslinking factor 1
MTO1 mitochondrial tRNA translation optimization 1
MUC7 mucin 7, secreted
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYO18A myosin XVIIIA
MYO9B myosin IXB
MYOM1 myomesin 1
N4BP2 NEDD4 binding protein 2
NCF1C neutrophil cytosolic factor 1C pseudogene
NCKAP1L NCK-associated protein 1-like
NDC80 NDC80 kinetochore complex component
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
NFAM1 NFAT activating protein with ITAM motif 1
NIN ninein (GSK3B interacting protein)
NLRC3 NLR family, CARD domain containing 3
NLRC5 NLR family, CARD domain containing 5
NMRK2 nicotinamide riboside kinase 2
NOS1 nitric oxide synthase 1 (neuronal)
NOVA1 neuro-oncological ventral antigen 1
NRD1 nardilysin (N-arginine dibasic convertase)
NUCB2 nucleobindin 2
NUGGC nuclear GTPase, germinal center associated
OR11H4 olfactory receptor, family 11, subfamily H, member 4
OR2G2 olfactory receptor, family 2, subfamily G, member 2
OR4D2 olfactory receptor, family 4, subfamily D, member 2
OR4S2 olfactory receptor, family 4, subfamily S, member 2
OR52N4 olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene)
OR56B1 olfactory receptor, family 56, subfamily B, member 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
P2RY8 purinergic receptor P2Y, G-protein coupled, 8
PAGE2 P antigen family, member 2 (prostate associated)
PARP15 poly (ADP-ribose) polymerase family, member 15
PARVG parvin, gamma
PAX5 paired box 5
PCDHGA1 protocadherin gamma subfamily A, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCNX pecanex homolog (Drosophila)
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
PI16 peptidase inhibitor 16
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLA2G2D phospholipase A2, group IID
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCB2 phospholipase C, beta 2
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PLIN1 perilipin 1
PLIN4 perilipin 4
PLXNC1 plexin C1
PMEL premelanosome protein
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POMC proopiomelanocortin
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCB protein kinase C, beta
PRM1 protamine 1
PSAT1 phosphoserine aminotransferase 1
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRT protein tyrosine phosphatase, receptor type, T
PUM1 pumilio RNA-binding family member 1
PVRIG poliovirus receptor related immunoglobulin domain containing
PYHIN1 pyrin and HIN domain family, member 1
RAB12 RAB12, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABGAP1 RAB GTPase activating protein 1
RAET1L retinoic acid early transcript 1L
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBP5 retinol binding protein 5, cellular
RC3H2 ring finger and CCCH-type domains 2
RCSD1 RCSD domain containing 1
REST RE1-silencing transcription factor
RGL4 ral guanine nucleotide dissociation stimulator-like 4
RGS9BP regulator of G protein signaling 9 binding protein
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RYR1 ryanodine receptor 1 (skeletal)
SASH3 SAM and SH3 domain containing 3
SCIMP SLP adaptor and CSK interacting membrane protein
SCML4 sex comb on midleg-like 4 (Drosophila)
SCN9A sodium channel, voltage gated, type IX alpha subunit
SERINC5 serine incorporator 5
SESN2 sestrin 2
SETX senataxin
SFMBT2 Scm-like with four mbt domains 2
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC10 sialic acid binding Ig-like lectin 10
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRPG signal-regulatory protein gamma
SLA Src-like-adaptor
SLA2 Src-like-adaptor 2
SLAMF1 signaling lymphocytic activation molecule family member 1
SLAMF6 SLAM family member 6
SLAMF8 SLAM family member 8
SLC25A45 solute carrier family 25, member 45
SLC26A7 solute carrier family 26 (anion exchanger), member 7
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLFN12L schlafen family member 12-like
SLFN14 schlafen family member 14
SLFN5 schlafen family member 5
SMAP2 small ArfGAP2
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SMR3A submaxillary gland androgen regulated protein 3A
SMTNL1 smoothelin-like 1
SNAI3 snail family zinc finger 3
SNORA56 small nucleolar RNA, H/ACA box 56
SNX20 sorting nexin 20
SNX29 sorting nexin 29
SNX29P2 sorting nexin 29 pseudogene 2
SOGA1 suppressor of glucose, autophagy associated 1
SP140 SP140 nuclear body protein
SPATA32 spermatogenesis associated 32
SREBF2 sterol regulatory element binding transcription factor 2
SSX6 synovial sarcoma, X breakpoint 6 (pseudogene)
STAB1 stabilin 1
STAB2 stabilin 2
STIM1 stromal interaction molecule 1
STK10 serine/threonine kinase 10
STK4 serine/threonine kinase 4
STRADB STE20-related kinase adaptor beta
STRN striatin, calmodulin binding protein
SYNE3 spectrin repeat containing, nuclear envelope family member 3
TAGAP T-cell activation RhoGTPase activating protein
TAS2R3 taste receptor, type 2, member 3
TCF20 transcription factor 20 (AR1)
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCN2 transcobalamin II
TDRD6 tudor domain containing 6
TESPA1 thymocyte expressed, positive selection associated 1
TIFAB TRAF-interacting protein with forkhead-associated domain, family member B
TIGIT T cell immunoreceptor with Ig and ITIM domains
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TLR9 toll-like receptor 9
TMEM63A transmembrane protein 63A
TMIGD1 transmembrane and immunoglobulin domain containing 1
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TRAF3IP3 TRAF3 interacting protein 3
TRAK2 trafficking protein, kinesin binding 2
TRAT1 T cell receptor associated transmembrane adaptor 1
TREML1 triggering receptor expressed on myeloid cells-like 1
TRIM14 tripartite motif containing 14
TSHZ2 teashirt zinc finger homeobox 2
TSPAN32 tetraspanin 32
TTC22 tetratricopeptide repeat domain 22
TTC24 tetratricopeptide repeat domain 24
TUSC5 tumor suppressor candidate 5
TXK TXK tyrosine kinase
UBASH3A ubiquitin associated and SH3 domain containing A
UHRF1BP1 UHRF1 binding protein 1
USP24 ubiquitin specific peptidase 24
USP35 ubiquitin specific peptidase 35
WARS tryptophanyl-tRNA synthetase
WAS Wiskott-Aldrich syndrome
WDFY4 WDFY family member 4
WDR64 WD repeat domain 64
WIPF1 WAS/WASL interacting protein family, member 1
XCR1 chemokine (C motif) receptor 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YPEL4 yippee-like 4 (Drosophila)
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZC3H12D zinc finger CCCH-type containing 12D
ZCCHC11 zinc finger, CCHC domain containing 11
ZDBF2 zinc finger, DBF-type containing 2
ZFYVE26 zinc finger, FYVE domain containing 26
ZNF101 zinc finger protein 101
ZNF208 zinc finger protein 208
ZNF257 zinc finger protein 257
ZNF442 zinc finger protein 442
ZNF527 zinc finger protein 527
ZNF569 zinc finger protein 569
ZNF570 zinc finger protein 570
ZNF573 zinc finger protein 573
ZNF592 zinc finger protein 592
ZNF676 zinc finger protein 676
ZNF735 zinc finger protein 735
ZNF737 zinc finger protein 737
ZNF831 zinc finger protein 831
ZYG11A zyg-11 family member A, cell cycle regulator