Lung squamous cell carcinoma_LUSC_TCGA-85-8353-01A-21R-2296-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

234 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-85-8353-01A-21R-2296-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTN1 actinin, alpha 1
ADAM19 ADAM metallopeptidase domain 19
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADGRA2 adhesion G protein-coupled receptor A2
ADGRF2 adhesion G protein-coupled receptor F2
AMH anti-Mullerian hormone
ANGPTL2 angiopoietin-like 2
ANKRD20A3 ankyrin repeat domain 20 family, member A3
ANKRD20A4 ankyrin repeat domain 20 family, member A4
ANKRD52 ankyrin repeat domain 52
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATXN1 ataxin 1
AZIN1 antizyme inhibitor 1
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
BICC1 BicC family RNA binding protein 1
BICD1 bicaudal D homolog 1 (Drosophila)
BMP8A bone morphogenetic protein 8a
C1ORF100 chromosome 1 open reading frame 100
C2CD4A C2 calcium-dependent domain containing 4A
C2CD4C C2 calcium-dependent domain containing 4C
C3ORF67 chromosome 3 open reading frame 67
C4ORF50 chromosome 4 open reading frame 50
C6ORF223 chromosome 6 open reading frame 223
C9ORF50 chromosome 9 open reading frame 50
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CARD10 caspase recruitment domain family, member 10
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC82 coiled-coil domain containing 82
CCNT1 cyclin T1
CD109 CD109 molecule
CDC73 cell division cycle 73
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKL5 cyclin-dependent kinase-like 5
CHRM3 cholinergic receptor, muscarinic 3
COL13A1 collagen, type XIII, alpha 1
COL15A1 collagen, type XV, alpha 1
COL18A1 collagen, type XVIII, alpha 1
COL18A1-AS1 COL18A1 antisense RNA 1
COL3A1 collagen, type III, alpha 1
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
COL5A1 collagen, type V, alpha 1
COL6A2 collagen, type VI, alpha 2
COL6A3 collagen, type VI, alpha 3
CORO6 coronin 6
CPA6 carboxypeptidase A6
CREG2 cellular repressor of E1A-stimulated genes 2
CRISPLD1 cysteine-rich secretory protein LCCL domain containing 1
CSMD2 CUB and Sushi multiple domains 2
CTSV cathepsin V
DCBLD2 discoidin, CUB and LCCL domain containing 2
DDIT3 DNA-damage-inducible transcript 3
DDR2 discoidin domain receptor tyrosine kinase 2
DDX59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
DIRC1 disrupted in renal carcinoma 1
DMRT1 doublesex and mab-3 related transcription factor 1
DNAJC25-GNG10 DNAJC25-GNG10 readthrough
DOCK6 dedicator of cytokinesis 6
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
DZIP1 DAZ interacting zinc finger protein 1
E2F7 E2F transcription factor 7
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EFNA2 ephrin-A2
EGLN3 egl-9 family hypoxia-inducible factor 3
EMILIN1 elastin microfibril interfacer 1
ERO1L ERO1-like (S. cerevisiae)
ETV3 ets variant 3
FAM110C family with sequence similarity 110, member C
FAM120B family with sequence similarity 120B
FAM129A family with sequence similarity 129, member A
FAM157A family with sequence similarity 157, member A
FAM157B family with sequence similarity 157, member B
FAM168A family with sequence similarity 168, member A
FAM210A family with sequence similarity 210, member A
FAM63B family with sequence similarity 63, member B
FBXL3 F-box and leucine-rich repeat protein 3
FLNA filamin A, alpha
FLRT2 fibronectin leucine rich transmembrane protein 2
FOXD1 forkhead box D1
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
GDI1 GDP dissociation inhibitor 1
GEM GTP binding protein overexpressed in skeletal muscle
GGT5 gamma-glutamyltransferase 5
GLIS3 GLIS family zinc finger 3
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GOLGA2 golgin A2
GPATCH8 G patch domain containing 8
GPR27 G protein-coupled receptor 27
GREM1 gremlin 1, DAN family BMP antagonist
GTPBP2 GTP binding protein 2
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HK2 hexokinase 2
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IER3 immediate early response 3
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4
IL1RAP interleukin 1 receptor accessory protein
IL7R interleukin 7 receptor
INHBA inhibin, beta A
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
ITGB4 integrin, beta 4
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
IVNS1ABP influenza virus NS1A binding protein
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KDM4B lysine (K)-specific demethylase 4B
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA0355 KIAA0355
KIF26B kinesin family member 26B
KIRREL kin of IRRE like (Drosophila)
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL34 kelch-like family member 34
LAMA3 laminin, alpha 3
LAMC1 laminin, gamma 1 (formerly LAMB2)
LATS1 large tumor suppressor kinase 1
LOXL2 lysyl oxidase-like 2
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRP1 low density lipoprotein receptor-related protein 1
MAPK7 mitogen-activated protein kinase 7
MCF2 MCF.2 cell line derived transforming sequence
METTL4 methyltransferase like 4
MIER2 mesoderm induction early response 1, family member 2
MKNK2 MAP kinase interacting serine/threonine kinase 2
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MN1 meningioma (disrupted in balanced translocation) 1
MOB3A MOB kinase activator 3A
MXRA5 matrix-remodelling associated 5
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYO5A myosin VA (heavy chain 12, myoxin)
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAV1 neuron navigator 1
NBPF15 neuroblastoma breakpoint family, member 15
NDC80 NDC80 kinetochore complex component
NDRG1 N-myc downstream regulated 1
NEURL1B neuralized E3 ubiquitin protein ligase 1B
NID2 nidogen 2 (osteonidogen)
NLGN2 neuroligin 2
NMUR2 neuromedin U receptor 2
NOX4 NADPH oxidase 4
NRP2 neuropilin 2
NTSR1 neurotensin receptor 1 (high affinity)
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
OR2L3 olfactory receptor, family 2, subfamily L, member 3
OSM oncostatin M
PCDHGB2 protocadherin gamma subfamily B, 2
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGF placental growth factor
PGM3 phosphoglucomutase 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIPOX pipecolic acid oxidase
PITPNM3 PITPNM family member 3
PLEC plectin
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
PLXNB3 plexin B3
PNCK pregnancy up-regulated nonubiquitous CaM kinase
POSTN periostin, osteoblast specific factor
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPP1R18 protein phosphatase 1, regulatory subunit 18
PRDM1 PR domain containing 1, with ZNF domain
PRELID2 PRELI domain containing 2
PRKCDBP protein kinase C, delta binding protein
PRPF3 pre-mRNA processing factor 3
PRPF8 pre-mRNA processing factor 8
PTCHD1 patched domain containing 1
PTHLH parathyroid hormone-like hormone
RAP2B RAP2B, member of RAS oncogene family
RASEF RAS and EF-hand domain containing
RC3H2 ring finger and CCCH-type domains 2
RGS16 regulator of G-protein signaling 16
RPSAP52 ribosomal protein SA pseudogene 52
RSPH3 radial spoke 3 homolog (Chlamydomonas)
RUNX1 runt-related transcription factor 1
S100A2 S100 calcium binding protein A2
SEBOX SEBOX homeobox
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SH3PXD2B SH3 and PX domains 2B
SHC4 SHC (Src homology 2 domain containing) family, member 4
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC35E3 solute carrier family 35, member E3
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SMS spermine synthase
SNORA5C small nucleolar RNA, H/ACA box 5C
SNX9 sorting nexin 9
SPRED3 sprouty-related, EVH1 domain containing 3
SPRY2 sprouty homolog 2 (Drosophila)
STC1 stanniocalcin 1
STK32B serine/threonine kinase 32B
SULF1 sulfatase 1
SYNE3 spectrin repeat containing, nuclear envelope family member 3
TAOK1 TAO kinase 1
TAS2R41 taste receptor, type 2, member 41
TBP TATA box binding protein
TFB1M transcription factor B1, mitochondrial
THBS2 thrombospondin 2
THOC1 THO complex 1
TM4SF19 transmembrane 4 L six family member 19
TMEM2 transmembrane protein 2
TNC tenascin C
TNIK TRAF2 and NCK interacting kinase
TNK1 tyrosine kinase, non-receptor, 1
TOR1AIP1 torsin A interacting protein 1
TPBG trophoblast glycoprotein
TPR translocated promoter region, nuclear basket protein
TRAM2 translocation associated membrane protein 2
TRIB3 tribbles pseudokinase 3
TRIM6-TRIM34 TRIM6-TRIM34 readthrough
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TSC22D2 TSC22 domain family, member 2
TSHZ3 teashirt zinc finger homeobox 3
TTBK2 tau tubulin kinase 2
TYMSOS TYMS opposite strand
UBXN7 UBX domain protein 7
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
UPP1 uridine phosphorylase 1
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
VEGFA vascular endothelial growth factor A
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZBTB34 zinc finger and BTB domain containing 34
ZBTB37 zinc finger and BTB domain containing 37
ZFAT-AS1 ZFAT antisense RNA 1
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP92 ZFP92 zinc finger protein
ZNF281 zinc finger protein 281
ZNF354C zinc finger protein 354C
ZNF653 zinc finger protein 653

low expression

Symbol Name
LRIF1 ligand dependent nuclear receptor interacting factor 1