Lung squamous cell carcinoma_LUSC_TCGA-85-8351-01A-11R-2296-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

364 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-85-8351-01A-11R-2296-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACTN1 actinin, alpha 1
ADGRL2 adhesion G protein-coupled receptor L2
ADSS adenylosuccinate synthase
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AKAP12 A kinase (PRKA) anchor protein 12
ALG6 ALG6, alpha-1,3-glucosyltransferase
ANKRD20A4 ankyrin repeat domain 20 family, member A4
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ANTXR2 anthrax toxin receptor 2
ANXA2 annexin A2
ANXA2P2 annexin A2 pseudogene 2
AOX2P aldehyde oxidase 2 pseudogene
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
AQP7P3 aquaporin 7 pseudogene 3
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL13A ADP-ribosylation factor-like 13A
ARL9 ADP-ribosylation factor-like 9
ARSJ arylsulfatase family, member J
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATG4C autophagy related 4C, cysteine peptidase
ATP13A3 ATPase type 13A3
BARX2 BARX homeobox 2
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BCAR1 breast cancer anti-estrogen resistance 1
BCL10 B-cell CLL/lymphoma 10
BCLAF1 BCL2-associated transcription factor 1
BEND3 BEN domain containing 3
BIVM basic, immunoglobulin-like variable motif containing
C10ORF2 chromosome 10 open reading frame 2
C15ORF39 chromosome 15 open reading frame 39
C17ORF70 chromosome 17 open reading frame 70
C19ORF48 chromosome 19 open reading frame 48
C2CD4A C2 calcium-dependent domain containing 4A
C8ORF48 chromosome 8 open reading frame 48
CA10 carbonic anhydrase X
CACHD1 cache domain containing 1
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
CAPN2 calpain 2, (m/II) large subunit
CD164 CD164 molecule, sialomucin
CD3EAP CD3e molecule, epsilon associated protein
CDC40 cell division cycle 40
CEP164 centrosomal protein 164kDa
CEP57L1 centrosomal protein 57kDa-like 1
CHD7 chromodomain helicase DNA binding protein 7
CHML choroideremia-like (Rab escort protein 2)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLUH clustered mitochondria (cluA/CLU1) homolog
COA7 cytochrome c oxidase assembly factor 7 (putative)
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
CREB5 cAMP responsive element binding protein 5
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSNK1D casein kinase 1, delta
CTU1 cytosolic thiouridylase subunit 1
CYB561 cytochrome b561
CYFIP1 cytoplasmic FMR1 interacting protein 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2
DCBLD2 discoidin, CUB and LCCL domain containing 2
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DFNA5 deafness, autosomal dominant 5
DHODH dihydroorotate dehydrogenase (quinone)
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DIEXF digestive organ expansion factor homolog (zebrafish)
DLEU2L deleted in lymphocytic leukemia 2-like
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOCK7 dedicator of cytokinesis 7
DOPEY1 dopey family member 1
DPH2 DPH2 homolog (S. cerevisiae)
DST dystonin
DTNA dystrobrevin, alpha
EEF2K eukaryotic elongation factor 2 kinase
EFCAB7 EF-hand calcium binding domain 7
EGFR epidermal growth factor receptor
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
ELAC2 elaC ribonuclease Z 2
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EMC10 ER membrane protein complex subunit 10
ENAH enabled homolog (Drosophila)
ERCC5 excision repair cross-complementation group 5
ESPNL espin-like
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM133A family with sequence similarity 133, member A
FAM57A family with sequence similarity 57, member A
FAM73A family with sequence similarity 73, member A
FAM86B1 family with sequence similarity 86, member B1
FAM86B2 family with sequence similarity 86, member B2
FASN fatty acid synthase
FBXL4 F-box and leucine-rich repeat protein 4
FBXO39 F-box protein 39
FGF5 fibroblast growth factor 5
FGGY FGGY carbohydrate kinase domain containing
FIG4 FIG4 phosphoinositide 5-phosphatase
FOXO3 forkhead box O3
FOXO3B forkhead box O3B pseudogene
FRMD5 FERM domain containing 5
FTSJ3 FtsJ homolog 3 (E. coli)
FUBP1 far upstream element (FUSE) binding protein 1
GALK2 galactokinase 2
GBA glucosidase, beta, acid
GBP7 guanylate binding protein 7
GEMIN4 gem (nuclear organelle) associated protein 4
GEMIN5 gem (nuclear organelle) associated protein 5
GLI3 GLI family zinc finger 3
GRM5 glutamate receptor, metabotropic 5
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
GYLTL1B glycosyltransferase-like 1B
HAS3 hyaluronan synthase 3
HDX highly divergent homeobox
HEATR1 HEAT repeat containing 1
HELZ helicase with zinc finger
HEPH hephaestin
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HMGA2 high mobility group AT-hook 2
HOOK1 hook microtubule-tethering protein 1
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
HS6ST2 heparan sulfate 6-O-sulfotransferase 2
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
IGF2R insulin-like growth factor 2 receptor
IL12RB2 interleukin 12 receptor, beta 2
IL15 interleukin 15
INADL InaD-like (Drosophila)
INHBB inhibin, beta B
INO80 INO80 complex subunit
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IPO4 importin 4
IPO9 importin 9
IQCH IQ motif containing H
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
ITGB4 integrin, beta 4
JAK1 Janus kinase 1
JOSD2 Josephin domain containing 2
JUN jun proto-oncogene
KCTD8 potassium channel tetramerization domain containing 8
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIAA1804 mixed lineage kinase 4
KLHL1 kelch-like family member 1
KLHL2 kelch-like family member 2
KLHL30 kelch-like family member 30
KLHL33 kelch-like family member 33
KRT75 keratin 75, type II
L3MBTL3 l(3)mbt-like 3 (Drosophila)
LAMP2 lysosomal-associated membrane protein 2
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LEPROT leptin receptor overlapping transcript
LIMS3-LOC440895 LIMS3-LOC440895 readthrough
LIN28B lin-28 homolog B (C. elegans)
LINC00346 long intergenic non-protein coding RNA 346
LIPG lipase, endothelial
LOC652276 potassium channel tetramerization domain containing 5 pseudogene
LPAR3 lysophosphatidic acid receptor 3
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MANBA mannosidase, beta A, lysosomal
MAP7D3 MAP7 domain containing 3
MCTP1 multiple C2 domains, transmembrane 1
MDN1 MDN1, midasin homolog (yeast)
MGA MGA, MAX dimerization protein
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MINK1 misshapen-like kinase 1
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MOCS3 molybdenum cofactor synthesis 3
MRPS9 mitochondrial ribosomal protein S9
MSN moesin
MTAP methylthioadenosine phosphorylase
MTG2 mitochondrial ribosome-associated GTPase 2
MYBBP1A MYB binding protein (P160) 1a
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYSM1 Myb-like, SWIRM and MPN domains 1
NAF1 nuclear assembly factor 1 ribonucleoprotein
NCL nucleolin
NDC1 NDC1 transmembrane nucleoporin
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFIA nuclear factor I/A
NLN neurolysin (metallopeptidase M3 family)
NOA1 nitric oxide associated 1
NOL11 nucleolar protein 11
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP14 NOP14 nucleolar protein
NR1H2 nuclear receptor subfamily 1, group H, member 2
NSUN4 NOP2/Sun domain family, member 4
NUP155 nucleoporin 155kDa
ODF2L outer dense fiber of sperm tails 2-like
OLAH oleoyl-ACP hydrolase
OMA1 OMA1 zinc metallopeptidase
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
OSMR oncostatin M receptor
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PAQR3 progestin and adipoQ receptor family member III
PCDHGA1 protocadherin gamma subfamily A, 1
PCDHGB2 protocadherin gamma subfamily B, 2
PDE10A phosphodiesterase 10A
PDLIM5 PDZ and LIM domain 5
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PFAS phosphoribosylformylglycinamidine synthase
PGA3 pepsinogen 3, group I (pepsinogen A)
PGA4 pepsinogen 4, group I (pepsinogen A)
PGA5 pepsinogen 5, group I (pepsinogen A)
PGF placental growth factor
PGM1 phosphoglucomutase 1
PGM2L1 phosphoglucomutase 2-like 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta
PKN2 protein kinase N2
PLAGL1 pleiomorphic adenoma gene-like 1
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
POPDC3 popeye domain containing 3
POU4F3 POU class 4 homeobox 3
PPAT phosphoribosyl pyrophosphate amidotransferase
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRDM8 PR domain containing 8
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PROSER3 proline and serine rich 3
PRRC2C proline-rich coiled-coil 2C
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PSD3 pleckstrin and Sec7 domain containing 3
PTPRK protein tyrosine phosphatase, receptor type, K
PVR poliovirus receptor
PXN paxillin
PYGL phosphorylase, glycogen, liver
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAVER2 ribonucleoprotein, PTB-binding 2
RBMXL1 RNA binding motif protein, X-linked-like 1
REST RE1-silencing transcription factor
RHOBTB3 Rho-related BTB domain containing 3
RIF1 replication timing regulatory factor 1
RIN1 Ras and Rab interactor 1
RITA1 RBPJ interacting and tubulin associated 1
RNF220 ring finger protein 220
RNMTL1 RNA methyltransferase like 1
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPF1 ribosome production factor 1 homolog (S. cerevisiae)
RPL4 ribosomal protein L4
RPUSD4 RNA pseudouridylate synthase domain containing 4
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae)
RTTN rotatin
SCFD2 sec1 family domain containing 2
SCO1 SCO1 cytochrome c oxidase assembly protein
SEC61G Sec61 gamma subunit
SEC63 SEC63 homolog (S. cerevisiae)
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SEPT9 septin 9
SERBP1 SERPINE1 mRNA binding protein 1
SESN1 sestrin 1
SF3B3 splicing factor 3b, subunit 3, 130kDa
SF3B6 splicing factor 3b, subunit 6, 14kDa
SGSH N-sulfoglucosamine sulfohydrolase
SH2D5 SH2 domain containing 5
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC35F2 solute carrier family 35, member F2
SLC38A1 solute carrier family 38, member 1
SLC39A10 solute carrier family 39 (zinc transporter), member 10
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNORA45B small nucleolar RNA, H/ACA box 45B
SOBP sine oculis binding protein homolog (Drosophila)
SOX7 SRY (sex determining region Y)-box 7
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRPK3 SRSF protein kinase 3
SSH1 slingshot protein phosphatase 1
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
STEAP3 STEAP family member 3, metalloreductase
STK4 serine/threonine kinase 4
STX1A syntaxin 1A (brain)
STX6 syntaxin 6
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
SYNE4 spectrin repeat containing, nuclear envelope family member 4
TACSTD2 tumor-associated calcium signal transducer 2
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBCK TBC1 domain containing kinase
TBX18 T-box 18
TEX30 testis expressed 30
TGIF2LX TGFB-induced factor homeobox 2-like, X-linked
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
TM2D1 TM2 domain containing 1
TMC7 transmembrane channel-like 7
TMEM192 transmembrane protein 192
TMEM241 transmembrane protein 241
TMEM69 transmembrane protein 69
TMPRSS15 transmembrane protease, serine 15
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TOP1 topoisomerase (DNA) I
TP53BP2 tumor protein p53 binding protein 2
TPBG trophoblast glycoprotein
TPD52L2 tumor protein D52-like 2
TPP2 tripeptidyl peptidase II
TPTE transmembrane phosphatase with tensin homology
TRERF1 transcriptional regulating factor 1
TRIM28 tripartite motif containing 28
TRIM47 tripartite motif containing 47
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC4 tetratricopeptide repeat domain 4
TTI1 TELO2 interacting protein 1
TXLNG taxilin gamma
UBE2O ubiquitin-conjugating enzyme E2O
UBE3D ubiquitin protein ligase E3D
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast)
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP1 ubiquitin specific peptidase 1
USP24 ubiquitin specific peptidase 24
USP36 ubiquitin specific peptidase 36
USP38 ubiquitin specific peptidase 38
USP43 ubiquitin specific peptidase 43
USP45 ubiquitin specific peptidase 45
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
VSTM2A V-set and transmembrane domain containing 2A
WASF1 WAS protein family, member 1
WDR17 WD repeat domain 17
WDR3 WD repeat domain 3
WDR36 WD repeat domain 36
WLS wntless Wnt ligand secretion mediator
YY2 YY2 transcription factor
ZBTB2 zinc finger and BTB domain containing 2
ZBTB24 zinc finger and BTB domain containing 24
ZBTB45 zinc finger and BTB domain containing 45
ZFP28 ZFP28 zinc finger protein
ZIK1 zinc finger protein interacting with K protein 1
ZNF132 zinc finger protein 132
ZNF134 zinc finger protein 134
ZNF146 zinc finger protein 146
ZNF239 zinc finger protein 239
ZNF324B zinc finger protein 324B
ZNF460 zinc finger protein 460
ZNF470 zinc finger protein 470
ZNF471 zinc finger protein 471
ZNF532 zinc finger protein 532
ZNF544 zinc finger protein 544
ZNF550 zinc finger protein 550
ZNF551 zinc finger protein 551
ZNF582 zinc finger protein 582
ZNF583 zinc finger protein 583
ZNF772 zinc finger protein 772
ZNF787 zinc finger protein 787
ZNF8 zinc finger protein 8
ZNF804A zinc finger protein 804A
ZNF84 zinc finger protein 84
ZNHIT6 zinc finger, HIT-type containing 6
ZSCAN22 zinc finger and SCAN domain containing 22
ZSCAN5A zinc finger and SCAN domain containing 5A
ZZZ3 zinc finger, ZZ-type containing 3