Lung squamous cell carcinoma_LUSC_TCGA-85-8287-01A-11R-2296-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

425 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-85-8287-01A-11R-2296-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AASDH aminoadipate-semialdehyde dehydrogenase
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6
ACVR2A activin A receptor, type IIA
ADAM6 ADAM metallopeptidase domain 6 (pseudogene)
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AEBP1 AE binding protein 1
AEN apoptosis enhancing nuclease
AFAP1 actin filament associated protein 1
AKAP9 A kinase (PRKA) anchor protein 9
AMPD1 adenosine monophosphate deaminase 1
ANGPTL2 angiopoietin-like 2
ANKRD6 ankyrin repeat domain 6
AOX2P aldehyde oxidase 2 pseudogene
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARID4B AT rich interactive domain 4B (RBP1-like)
ARL9 ADP-ribosylation factor-like 9
ARSJ arylsulfatase family, member J
ASB3 ankyrin repeat and SOCS box containing 3
ATF2 activating transcription factor 2
ATF7 activating transcription factor 7
ATOH1 atonal homolog 1 (Drosophila)
ATRX alpha thalassemia/mental retardation syndrome X-linked
ATXN7L1 ataxin 7-like 1
AUTS2 autism susceptibility candidate 2
AVPR1A arginine vasopressin receptor 1A
BAALC brain and acute leukemia, cytoplasmic
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BBS9 Bardet-Biedl syndrome 9
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BOD1L1 biorientation of chromosomes in cell division 1-like 1
BRD2 bromodomain containing 2
BRPF3 bromodomain and PHD finger containing, 3
BTN2A1 butyrophilin, subfamily 2, member A1
C11ORF95 chromosome 11 open reading frame 95
C17ORF70 chromosome 17 open reading frame 70
C1QTNF1 C1q and tumor necrosis factor related protein 1
C22ORF24 chromosome 22 open reading frame 24
C6ORF222 chromosome 6 open reading frame 222
C8ORF31 chromosome 8 open reading frame 31
CAB39 calcium binding protein 39
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CANT1 calcium activated nucleotidase 1
CASD1 CAS1 domain containing 1
CASP8AP2 caspase 8 associated protein 2
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC102A coiled-coil domain containing 102A
CCDC144CP coiled-coil domain containing 144C, pseudogene
CCDC186 coiled-coil domain containing 186
CCDC36 coiled-coil domain containing 36
CCDC80 coiled-coil domain containing 80
CCL11 chemokine (C-C motif) ligand 11
CCL28 chemokine (C-C motif) ligand 28
CD163L1 CD163 molecule-like 1
CD27 CD27 molecule
CDH13 cadherin 13
CDK14 cyclin-dependent kinase 14
CECR7 cat eye syndrome chromosome region, candidate 7 (non-protein coding)
CEMIP cell migration inducing protein, hyaluronan binding
CEP135 centrosomal protein 135kDa
CEP162 centrosomal protein 162kDa
CFHR1 complement factor H-related 1
CGGBP1 CGG triplet repeat binding protein 1
CHD3 chromodomain helicase DNA binding protein 3
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CIB2 calcium and integrin binding family member 2
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLIP2 CAP-GLY domain containing linker protein 2
CLOCK clock circadian regulator
CLRN3 clarin 3
CMTM1 CKLF-like MARVEL transmembrane domain containing 1
CMTM3 CKLF-like MARVEL transmembrane domain containing 3
CNPY4 canopy FGF signaling regulator 4
CNTN3 contactin 3 (plasmacytoma associated)
COL11A1 collagen, type XI, alpha 1
COL12A1 collagen, type XII, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL22A1 collagen, type XXII, alpha 1
COL26A1 collagen, type XXVI, alpha 1
COL3A1 collagen, type III, alpha 1
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
COL6A1 collagen, type VI, alpha 1
COL6A3 collagen, type VI, alpha 3
COL6A6 collagen, type VI, alpha 6
CPNE5 copine V
CPXM1 carboxypeptidase X (M14 family), member 1
CRABP1 cellular retinoic acid binding protein 1
CRAMP1L Crm, cramped-like (Drosophila)
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CROT carnitine O-octanoyltransferase
CSMD1 CUB and Sushi multiple domains 1
CSMD2 CUB and Sushi multiple domains 2
CSRNP3 cysteine-serine-rich nuclear protein 3
CTCF CCCTC-binding factor (zinc finger protein)
CTSK cathepsin K
CTSL3P cathepsin L family member 3, pseudogene
CTTN cortactin
CXCL12 chemokine (C-X-C motif) ligand 12
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
CYP4X1 cytochrome P450, family 4, subfamily X, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
CYTH1 cytohesin 1
DCHS1 dachsous cadherin-related 1
DCP2 decapping mRNA 2
DERL3 derlin 3
DET1 de-etiolated homolog 1 (Arabidopsis)
DKFZP434K028 uncharacterized LOC26070
DKFZP586I1420 uncharacterized protein DKFZp586I1420
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK2 delta-like 2 homolog (Drosophila)
DMTF1 cyclin D binding myb-like transcription factor 1
DNAH17 dynein, axonemal, heavy chain 17
DOPEY1 dopey family member 1
DPT dermatopontin
DUSP16 dual specificity phosphatase 16
DUSP2 dual specificity phosphatase 2
EBF4 early B-cell factor 4
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ENGASE endo-beta-N-acetylglucosaminidase
EOMES eomesodermin
EPC2 enhancer of polycomb homolog 2 (Drosophila)
EPHB4 EPH receptor B4
EVC Ellis van Creveld protein
EVX2 even-skipped homeobox 2
EXOC1 exocyst complex component 1
FAM101A family with sequence similarity 101, member A
FAM106CP family with sequence similarity 106, member C, pseudogene
FAM161A family with sequence similarity 161, member A
FAM170B family with sequence similarity 170, member B
FAM41C family with sequence similarity 41, member C
FAM65C family with sequence similarity 65, member C
FANCI Fanconi anemia, complementation group I
FBLN1 fibulin 1
FBLN2 fibulin 2
FBN3 fibrillin 3
FGD6 FYVE, RhoGEF and PH domain containing 6
FIBIN fin bud initiation factor homolog (zebrafish)
FILIP1L filamin A interacting protein 1-like
FKBP14 FK506 binding protein 14, 22 kDa
FLJ42627 uncharacterized LOC645644
FNDC1 fibronectin type III domain containing 1
FOXC1 forkhead box C1
FOXD4L3 forkhead box D4-like 3
FOXP3 forkhead box P3
FRK fyn-related Src family tyrosine kinase
FSTL1 follistatin-like 1
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GATS GATS, stromal antigen 3 opposite strand
GATSL2 GATS protein-like 2
GDPGP1 GDP-D-glucose phosphorylase 1
GEM GTP binding protein overexpressed in skeletal muscle
GH1 growth hormone 1
GHR growth hormone receptor
GIGYF1 GRB10 interacting GYF protein 1
GIGYF2 GRB10 interacting GYF protein 2
GLI3 GLI family zinc finger 3
GLT8D1 glycosyltransferase 8 domain containing 1
GLTSCR1L GLTSCR1-like
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GOPC golgi-associated PDZ and coiled-coil motif containing
GPR158 G protein-coupled receptor 158
GPR55 G protein-coupled receptor 55
GRIP2 glutamate receptor interacting protein 2
GRM2 glutamate receptor, metabotropic 2
GTF2I general transcription factor IIi
GTF2IP1 general transcription factor IIi pseudogene 1
GTF2IRD2 GTF2I repeat domain containing 2
GTF2IRD2P1 GTF2I repeat domain containing 2 pseudogene 1
GXYLT2 glucoside xylosyltransferase 2
GYLTL1B glycosyltransferase-like 1B
GYS2 glycogen synthase 2 (liver)
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIP1 huntingtin interacting protein 1
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HOXA9 homeobox A9
HPYR1 Helicobacter pylori responsive 1 (non-protein coding)
HSPG2 heparan sulfate proteoglycan 2
IBSP integrin-binding sialoprotein
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4
IL22RA2 interleukin 22 receptor, alpha 2
INO80D INO80 complex subunit D
IREB2 iron-responsive element binding protein 2
IRF7 interferon regulatory factor 7
IRX4 iroquois homeobox 4
IRX5 iroquois homeobox 5
ISG20 interferon stimulated exonuclease gene 20kDa
ISM1 isthmin 1, angiogenesis inhibitor
KBTBD2 kelch repeat and BTB (POZ) domain containing 2
KCTD7 potassium channel tetramerization domain containing 7
KIAA1211 KIAA1211
KIAA1324L KIAA1324-like
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KMT2A lysine (K)-specific methyltransferase 2A
KMT2E lysine (K)-specific methyltransferase 2E
KPNA5 karyopherin alpha 5 (importin alpha 6)
LAMB1 laminin, beta 1
LAMB4 laminin, beta 4
LATS1 large tumor suppressor kinase 1
LAX1 lymphocyte transmembrane adaptor 1
LINC00029 long intergenic non-protein coding RNA 29
LINC01548 long intergenic non-protein coding RNA 1548
LINC01590 long intergenic non-protein coding RNA 1590
LINC01600 long intergenic non-protein coding RNA 1600
LOC100130093 uncharacterized LOC100130093
LOC100133050 glucuronidase, beta pseudogene
LOC283922 pyruvate dehydrogenase phosphatase regulatory subunit pseudogene
LRP4 low density lipoprotein receptor-related protein 4
LRP5 low density lipoprotein receptor-related protein 5
LRRC15 leucine rich repeat containing 15
LRRN4CL LRRN4 C-terminal like
LZTS1 leucine zipper, putative tumor suppressor 1
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MARCH11 membrane-associated ring finger (C3HC4) 11
MARVELD1 MARVEL domain containing 1
MBD5 methyl-CpG binding domain protein 5
MBTPS1 membrane-bound transcription factor peptidase, site 1
MDN1 MDN1, midasin homolog (yeast)
MED13L mediator complex subunit 13-like
MEI1 meiosis inhibitor 1
MEX3B mex-3 RNA binding family member B
MFGE8 milk fat globule-EGF factor 8 protein
MGC16142 uncharacterized protein MGC16142
MMP11 matrix metallopeptidase 11
MMP2 matrix metallopeptidase 2
MMP27 matrix metallopeptidase 27
MOB1B MOB kinase activator 1B
MON1B MON1 secretory trafficking family member B
MORN3 MORN repeat containing 3
MOXD1 monooxygenase, DBH-like 1
MRPL46 mitochondrial ribosomal protein L46
MRPS11 mitochondrial ribosomal protein S11
MSTN myostatin
MTNR1A melatonin receptor 1A
N4BP2 NEDD4 binding protein 2
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D
NCOA2 nuclear receptor coactivator 2
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1
NFYA nuclear transcription factor Y, alpha
NGRN neugrin, neurite outgrowth associated
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR2C2 nuclear receptor subfamily 2, group C, member 2
NTN1 netrin 1
NTN3 netrin 3
NUAK1 NUAK family, SNF1-like kinase, 1
NWD1 NACHT and WD repeat domain containing 1
OCLM oculomedin
OMD osteomodulin
OR2L13 olfactory receptor, family 2, subfamily L, member 13
OR2L1P olfactory receptor, family 2, subfamily L, member 1 pseudogene
OR2L3 olfactory receptor, family 2, subfamily L, member 3
OR4F29 olfactory receptor, family 4, subfamily F, member 29
OR52N4 olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene)
ORAI2 ORAI calcium release-activated calcium modulator 2
OSBPL5 oxysterol binding protein-like 5
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PBRM1 polybromo 1
PCDHA4 protocadherin alpha 4
PCDHB11 protocadherin beta 11
PCDHB2 protocadherin beta 2
PCDHGA5 protocadherin gamma subfamily A, 5
PCDHGB2 protocadherin gamma subfamily B, 2
PCGEM1 PCGEM1, prostate-specific transcript (non-protein coding)
PCLO piccolo presynaptic cytomatrix protein
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
PDE7A phosphodiesterase 7A
PDGFA platelet-derived growth factor alpha polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRL platelet-derived growth factor receptor-like
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PDZRN3 PDZ domain containing ring finger 3
PGS1 phosphatidylglycerophosphate synthase 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PHF20 PHD finger protein 20
PIWIL2 piwi-like RNA-mediated gene silencing 2
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLXDC1 plexin domain containing 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POLG polymerase (DNA directed), gamma
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POM121 POM121 transmembrane nucleoporin
POM121C POM121 transmembrane nucleoporin C
POTEE POTE ankyrin domain family, member E
POU6F2 POU class 6 homeobox 2
PP2D1 protein phosphatase 2C-like domain containing 1
PPAT phosphoribosyl pyrophosphate amidotransferase
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASA4 RAS p21 protein activator 4
RBMXL2 RNA binding motif protein, X-linked-like 2
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RGS13 regulator of G-protein signaling 13
RGS21 regulator of G-protein signaling 21
RIF1 replication timing regulatory factor 1
RIMS2 regulating synaptic membrane exocytosis 2
RNF152 ring finger protein 152
RNF212 ring finger protein 212
RSBN1L round spermatid basic protein 1-like
RUFY3 RUN and FYVE domain containing 3
RUNX2 runt-related transcription factor 2
SATB1 SATB homeobox 1
SCRN1 secernin 1
SEC14L1 SEC14-like 1 (S. cerevisiae)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SENP6 SUMO1/sentrin specific peptidase 6
SEPT9 septin 9
SETD5 SET domain containing 5
SFRP4 secreted frizzled-related protein 4
SGCE sarcoglycan, epsilon
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SH3PXD2B SH3 and PX domains 2B
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
SLC10A5 solute carrier family 10, member 5
SLC25A40 solute carrier family 25, member 40
SLC35G6 solute carrier family 35, member G6
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNORA25 small nucleolar RNA, H/ACA box 25
SNORA4 small nucleolar RNA, H/ACA box 4
SNORA65 small nucleolar RNA, H/ACA box 65
SOX7 SRY (sex determining region Y)-box 7
SPACA5 sperm acrosome associated 5
SPANXN3 SPANX family, member N3
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPATA2 spermatogenesis associated 2
SRP72 signal recognition particle 72kDa
SRPK2 SRSF protein kinase 2
SRRT serrate, RNA effector molecule
SSPN sarcospan
STAG3L2 stromal antigen 3-like 2 (pseudogene)
STEAP2 STEAP family member 2, metalloreductase
STMN3 stathmin-like 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
SYCP2L synaptonemal complex protein 2-like
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TAS1R3 taste receptor, type 1, member 3
TATDN2 TatD DNase domain containing 2
TBC1D32 TBC1 domain family, member 32
TBC1D5 TBC1 domain family, member 5
TCF23 transcription factor 23
TDO2 tryptophan 2,3-dioxygenase
TECRL trans-2,3-enoyl-CoA reductase-like
TECTA tectorin alpha
TFCP2L1 transcription factor CP2-like 1
THBS2 thrombospondin 2
THSD7B thrombospondin, type I, domain containing 7B
TIAM2 T-cell lymphoma invasion and metastasis 2
TICRR TOPBP1-interacting checkpoint and replication regulator
TIMP2 TIMP metallopeptidase inhibitor 2
TMEM150C transmembrane protein 150C
TMEM151B transmembrane protein 151B
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNRC6C trinucleotide repeat containing 6C
TOP2B topoisomerase (DNA) II beta 180kDa
TP53TG1 TP53 target 1 (non-protein coding)
TRIL TLR4 interactor with leucine-rich repeats
TRIM42 tripartite motif containing 42
TRIM56 tripartite motif containing 56
TRIM78P tripartite motif containing 78, pseudogene
TSC22D4 TSC22 domain family, member 4
TTLL13P tubulin tyrosine ligase-like family member 13, pseudogene
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
TYW5 tRNA-yW synthesizing protein 5
UBTFL1 upstream binding transcription factor, RNA polymerase I-like 1
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
USP36 ubiquitin specific peptidase 36
USP50 ubiquitin specific peptidase 50
VCAN versican
VGLL4 vestigial-like family member 4
VWA2 von Willebrand factor A domain containing 2
WDR82 WD repeat domain 82
WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules
WIPF1 WAS/WASL interacting protein family, member 1
WNT10A wingless-type MMTV integration site family, member 10A
XKR5 XK, Kell blood group complex subunit-related family, member 5
XYLT1 xylosyltransferase I
ZBP1 Z-DNA binding protein 1
ZBTB12 zinc finger and BTB domain containing 12
ZBTB49 zinc finger and BTB domain containing 49
ZCCHC5 zinc finger, CCHC domain containing 5
ZDHHC17 zinc finger, DHHC-type containing 17
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF107 zinc finger protein 107
ZNF251 zinc finger protein 251
ZNF292 zinc finger protein 292
ZNF334 zinc finger protein 334
ZNF500 zinc finger protein 500
ZNF654 zinc finger protein 654
ZNF679 zinc finger protein 679
ZNF713 zinc finger protein 713
ZNF727 zinc finger protein 727
ZNF785 zinc finger protein 785
ZNF80 zinc finger protein 80
ZNF821 zinc finger protein 821
ZNF827 zinc finger protein 827
ZSCAN12 zinc finger and SCAN domain containing 12
ZSCAN2 zinc finger and SCAN domain containing 2