Lung squamous cell carcinoma_LUSC_TCGA-85-8072-01A-31R-2247-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

409 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-85-8072-01A-31R-2247-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AANAT aralkylamine N-acetyltransferase
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABHD1 abhydrolase domain containing 1
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1
ACR acrosin
ADAM11 ADAM metallopeptidase domain 11
ADCY3 adenylate cyclase 3
ADCY7 adenylate cyclase 7
AFG3L1P AFG3-like AAA ATPase 1, pseudogene
AFP alpha-fetoprotein
AGBL5 ATP/GTP binding protein-like 5
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9
AGPS alkylglycerone phosphate synthase
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2
ALS2CL ALS2 C-terminal like
AMH anti-Mullerian hormone
ANAPC15 anaphase promoting complex subunit 15
ANKRD52 ankyrin repeat domain 52
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6
ANKUB1 ankyrin repeat and ubiquitin domain containing 1
ANO1 anoctamin 1, calcium activated chloride channel
AQP10 aquaporin 10
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ATF2 activating transcription factor 2
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
ATRN attractin
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BOC BOC cell adhesion associated, oncogene regulated
BTBD11 BTB (POZ) domain containing 11
C1ORF100 chromosome 1 open reading frame 100
C1ORF111 chromosome 1 open reading frame 111
C1ORF226 chromosome 1 open reading frame 226
C1ORF229 chromosome 1 open reading frame 229
C21ORF2 chromosome 21 open reading frame 2
C21ORF58 chromosome 21 open reading frame 58
C2ORF48 chromosome 2 open reading frame 48
C4ORF50 chromosome 4 open reading frame 50
C6ORF1 chromosome 6 open reading frame 1
C8ORF46 chromosome 8 open reading frame 46
CA8 carbonic anhydrase VIII
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALB2 calbindin 2
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CBX2 chromobox homolog 2
CCDC102A coiled-coil domain containing 102A
CCL26 chemokine (C-C motif) ligand 26
CCNA1 cyclin A1
CCND1 cyclin D1
CCR3 chemokine (C-C motif) receptor 3
CCSER1 coiled-coil serine-rich protein 1
CDCA7 cell division cycle associated 7
CDH24 cadherin 24, type 2
CDK10 cyclin-dependent kinase 10
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CENPT centromere protein T
CEP152 centrosomal protein 152kDa
CEP68 centrosomal protein 68kDa
CHP2 calcineurin-like EF-hand protein 2
CIB3 calcium and integrin binding family member 3
CIR1 corepressor interacting with RBPJ, 1
CIZ1 CDKN1A interacting zinc finger protein 1
CLCN7 chloride channel, voltage-sensitive 7
CLDN8 claudin 8
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLK2 CDC-like kinase 2
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CMTR2 cap methyltransferase 2
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COL9A3 collagen, type IX, alpha 3
COLCA1 colorectal cancer associated 1
CORO2B coronin, actin binding protein, 2B
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRAT carnitine O-acetyltransferase
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CXORF58 chromosome X open reading frame 58
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
DAB2IP DAB2 interacting protein
DBIL5P diazepam binding inhibitor-like 5, pseudogene
DCTN1 dynactin 1
DENND4B DENN/MADD domain containing 4B
DFNB59 deafness, autosomal recessive 59
DHCR7 7-dehydrocholesterol reductase
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DIRAS2 DIRAS family, GTP-binding RAS-like 2
DKFZP434J0226 uncharacterized LOC93429
DMRT1 doublesex and mab-3 related transcription factor 1
DMTN dematin actin binding protein
DPRXP4 divergent-paired related homeobox pseudogene 4
DRD4 dopamine receptor D4
DRP2 dystrophin related protein 2
DSTYK dual serine/threonine and tyrosine protein kinase
DUT deoxyuridine triphosphatase
EDDM3B epididymal protein 3B
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPT1 ethanolaminephosphotransferase 1
ERMP1 endoplasmic reticulum metallopeptidase 1
EXOC8 exocyst complex component 8
EYA1 EYA transcriptional coactivator and phosphatase 1
FADD Fas (TNFRSF6)-associated via death domain
FAM102A family with sequence similarity 102, member A
FAM157A family with sequence similarity 157, member A
FAM157B family with sequence similarity 157, member B
FAM160B2 family with sequence similarity 160, member B2
FAM50B family with sequence similarity 50, member B
FAM86C1 family with sequence similarity 86, member C1
FAM90A7P putative protein FAM90A7
FBXL8 F-box and leucine-rich repeat protein 8
FBXO48 F-box protein 48
FGD1 FYVE, RhoGEF and PH domain containing 1
FLCN folliculin
FLG filaggrin
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FLYWCH1 FLYWCH-type zinc finger 1
FOXD4 forkhead box D4
FOXD4L5 forkhead box D4-like 5
FSCN2 fascin actin-bundling protein 2, retinal
FUK fucokinase
GAA glucosidase, alpha; acid
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GAS8-AS1 GAS8 antisense RNA 1
GATS GATS, stromal antigen 3 opposite strand
GATSL2 GATS protein-like 2
GCLM glutamate-cysteine ligase, modifier subunit
GEN1 GEN1 Holliday junction 5' flap endonuclease
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLIS3 GLIS family zinc finger 3
GMEB2 glucocorticoid modulatory element binding protein 2
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GPATCH11 G patch domain containing 11
GRIPAP1 GRIP1 associated protein 1
GSG2 germ cell associated 2 (haspin)
GSR glutathione reductase
GSTM4 glutathione S-transferase mu 4
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
H2AFX H2A histone family, member X
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HCLS1 hematopoietic cell-specific Lyn substrate 1
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HES4 hes family bHLH transcription factor 4
HHIPL2 HHIP-like 2
HIST3H3 histone cluster 3, H3
HLX H2.0-like homeobox
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HPCAL1 hippocalcin-like 1
HRCT1 histidine rich carboxyl terminus 1
HRNR hornerin
HS1BP3 HCLS1 binding protein 3
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
HSPA12A heat shock 70kDa protein 12A
HUS1B HUS1 checkpoint homolog b (S. pombe)
IFNA8 interferon, alpha 8
IL6R interleukin 6 receptor
ILDR1 immunoglobulin-like domain containing receptor 1
INPPL1 inositol polyphosphate phosphatase-like 1
IQGAP3 IQ motif containing GTPase activating protein 3
IQSEC2 IQ motif and Sec7 domain 2
IRGC immunity-related GTPase family, cinema
IRS2 insulin receptor substrate 2
JAKMIP3 Janus kinase and microtubule interacting protein 3
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KBTBD13 kelch repeat and BTB (POZ) domain containing 13
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2
KHK ketohexokinase (fructokinase)
KIAA0319 KIAA0319
KIAA1804 mixed lineage kinase 4
KIF3C kinesin family member 3C
KLF11 Kruppel-like factor 11
KLHL36 kelch-like family member 36
KRTCAP3 keratinocyte associated protein 3
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMC3 laminin, gamma 3
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LBX2 ladybird homeobox 2
LIN54 lin-54 DREAM MuvB core complex component
LINC00319 long intergenic non-protein coding RNA 319
LINC00521 long intergenic non-protein coding RNA 521
LOC100128554 uncharacterized LOC100128554
LOC100129550 uncharacterized LOC100129550
LOC100132287 uncharacterized LOC100132287
LOC100133331 uncharacterized LOC100133331
LOC100190986 uncharacterized LOC100190986
LOC143666 uncharacterized LOC143666
LOC145783 uncharacterized LOC145783
LOC388242 coiled-coil domain containing 101 pseudogene
LOC613037 nuclear pore complex interacting protein pseudogene
LOC642852 uncharacterized LOC642852
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC37A3 leucine rich repeat containing 37, member A3
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LYZL6 lysozyme-like 6
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAP2 microtubule-associated protein 2
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MARC1 mitochondrial amidoxime reducing component 1
MARVELD1 MARVEL domain containing 1
MATN2 matrilin 2
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1
METAP1D methionyl aminopeptidase type 1D (mitochondrial)
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MGC12916 uncharacterized protein MGC12916
MIR600HG MIR600 host gene
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MOB3C MOB kinase activator 3C
MON1B MON1 secretory trafficking family member B
MSC musculin
MSH5 mutS homolog 5
MTHFSD methenyltetrahydrofolate synthetase domain containing
MTX2 metaxin 2
MYLK4 myosin light chain kinase family, member 4
NADSYN1 NAD synthetase 1
NBEAL2 neurobeachin-like 2
NCF2 neutrophil cytosolic factor 2
NDRG4 NDRG family member 4
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NFASC neurofascin
NHLH1 nescient helix loop helix 1
NLGN3 neuroligin 3
NLRC5 NLR family, CARD domain containing 5
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOTCH3 notch 3
NOXA1 NADPH oxidase activator 1
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
NPR2 natriuretic peptide receptor 2
NQO2 NAD(P)H dehydrogenase, quinone 2
NR0B1 nuclear receptor subfamily 0, group B, member 1
NRBP1 nuclear receptor binding protein 1
NT5DC3 5'-nucleotidase domain containing 3
NT5M 5',3'-nucleotidase, mitochondrial
NUAK2 NUAK family, SNF1-like kinase, 2
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
NUMA1 nuclear mitotic apparatus protein 1
NUP210 nucleoporin 210kDa
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OLA1 Obg-like ATPase 1
OR2H2 olfactory receptor, family 2, subfamily H, member 2
OR4D2 olfactory receptor, family 4, subfamily D, member 2
OR4K1 olfactory receptor, family 4, subfamily K, member 1
ORAOV1 oral cancer overexpressed 1
OSBPL6 oxysterol binding protein-like 6
OSGIN1 oxidative stress induced growth inhibitor 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PALM2 paralemmin 2
PANX2 pannexin 2
PAQR6 progestin and adipoQ receptor family member VI
PC pyruvate carboxylase
PFAS phosphoribosylformylglycinamidine synthase
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PFKL phosphofructokinase, liver
PHEX phosphate regulating endopeptidase homolog, X-linked
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PIR pirin (iron-binding nuclear protein)
PKDREJ polycystin (PKD) family receptor for egg jelly
PKNOX1 PBX/knotted 1 homeobox 1
PLA2G10 phospholipase A2, group X
PLB1 phospholipase B1
PLD2 phospholipase D2
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
PLIN5 perilipin 5
PLXNA2 plexin A2
PMVK phosphomevalonate kinase
POLQ polymerase (DNA directed), theta
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2
PPP1R26 protein phosphatase 1, regulatory subunit 26
PPP1R3G protein phosphatase 1, regulatory subunit 3G
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRDM16 PR domain containing 16
PRMT2 protein arginine methyltransferase 2
PRSS16 protease, serine, 16 (thymus)
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PTPRD protein tyrosine phosphatase, receptor type, D
RAB10 RAB10, member RAS oncogene family
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB43 RAB43, member RAS oncogene family
RABL2A RAB, member of RAS oncogene family-like 2A
RAP1GAP RAP1 GTPase activating protein
RAP2B RAP2B, member of RAS oncogene family
RBBP5 retinoblastoma binding protein 5
RBM15 RNA binding motif protein 15
RBM19 RNA binding motif protein 19
RBP3 retinol binding protein 3, interstitial
RELT RELT tumor necrosis factor receptor
RFX3 regulatory factor X, 3 (influences HLA class II expression)
RNF121 ring finger protein 121
RNF151 ring finger protein 151
RNPEP arginyl aminopeptidase (aminopeptidase B)
RPL23AP7 ribosomal protein L23a pseudogene 7
RPS10P7 ribosomal protein S10 pseudogene 7
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SACS sacsin molecular chaperone
SAXO1 stabilizer of axonemal microtubules 1
SBF1 SET binding factor 1
SCAMP3 secretory carrier membrane protein 3
SCIN scinderin
SCN2A sodium channel, voltage gated, type II alpha subunit
SCRN3 secernin 3
SFXN5 sideroflexin 5
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SHISA4 shisa family member 4
SHISA9 shisa family member 9
SIX2 SIX homeobox 2
SIX3 SIX homeobox 3
SKOR1 SKI family transcriptional corepressor 1
SLC12A8 solute carrier family 12, member 8
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12
SLC38A7 solute carrier family 38, member 7
SLC46A1 solute carrier family 46 (folate transporter), member 1
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SLC7A5P2 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2
SLX1B SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
SMOC2 SPARC related modular calcium binding 2
SMYD3 SET and MYND domain containing 3
SMYD5 SMYD family member 5
SNORA62 small nucleolar RNA, H/ACA box 62
SNORA65 small nucleolar RNA, H/ACA box 65
SOWAHB sosondowah ankyrin repeat domain family member B
SP3 Sp3 transcription factor
SPATA12 spermatogenesis associated 12
SPATA20 spermatogenesis associated 20
SPATC1L spermatogenesis and centriole associated 1-like
SPP1 secreted phosphoprotein 1
SPRN shadow of prion protein homolog (zebrafish)
SPRYD7 SPRY domain containing 7
SQSTM1 sequestosome 1
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYCE1L synaptonemal complex central element protein 1-like
SYCE3 synaptonemal complex central element protein 3
TCP10L t-complex 10-like
TDP2 tyrosyl-DNA phosphodiesterase 2
TDRD6 tudor domain containing 6
TEX38 testis expressed 38
THNSL2 threonine synthase-like 2 (S. cerevisiae)
THSD7A thrombospondin, type I, domain containing 7A
TM4SF19 transmembrane 4 L six family member 19
TMCC2 transmembrane and coiled-coil domain family 2
TMEM105 transmembrane protein 105
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNK2 tyrosine kinase, non-receptor, 2
TOR2A torsin family 2, member A
TP53I13 tumor protein p53 inducible protein 13
TPGS1 tubulin polyglutamylase complex subunit 1
TREML3P triggering receptor expressed on myeloid cells-like 3, pseudogene
TRIM16 tripartite motif containing 16
TRIM16L tripartite motif containing 16-like
TRIM25 tripartite motif containing 25
TRIM6 tripartite motif containing 6
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC1 tuberous sclerosis 1
TSPAN7 tetraspanin 7
TSSK3 testis-specific serine kinase 3
TTC22 tetratricopeptide repeat domain 22
TTC30A tetratricopeptide repeat domain 30A
TTC30B tetratricopeptide repeat domain 30B
TTC7A tetratricopeptide repeat domain 7A
TTTY14 testis-specific transcript, Y-linked 14 (non-protein coding)
TTTY1B testis-specific transcript, Y-linked 1B (non-protein coding)
TTTY2 testis-specific transcript, Y-linked 2 (non-protein coding)
TTYH2 tweety family member 2
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBAP2L ubiquitin associated protein 2-like
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1
UBQLN4 ubiquilin 4
UBXN2A UBX domain protein 2A
UCN urocortin
UNKL unkempt family zinc finger-like
USP10 ubiquitin specific peptidase 10
VPS9D1 VPS9 domain containing 1
WASF1 WAS protein family, member 1
WBSCR16 Williams-Beuren syndrome chromosome region 16
WNT11 wingless-type MMTV integration site family, member 11
WNT9A wingless-type MMTV integration site family, member 9A
YBX2 Y box binding protein 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZC3H18 zinc finger CCCH-type containing 18
ZC3H4 zinc finger CCCH-type containing 4
ZC3HAV1L zinc finger CCCH-type, antiviral 1-like
ZDHHC18 zinc finger, DHHC-type containing 18
ZDHHC23 zinc finger, DHHC-type containing 23
ZFPM1 zinc finger protein, FOG family member 1
ZNF292 zinc finger protein 292
ZNF319 zinc finger protein 319
ZNF496 zinc finger protein 496
ZNF746 zinc finger protein 746
ZSCAN31 zinc finger and SCAN domain containing 31

low expression

Symbol Name
BBS7 Bardet-Biedl syndrome 7
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
PEX7 peroxisomal biogenesis factor 7
PGGT1B protein geranylgeranyltransferase type I, beta subunit