Lung squamous cell carcinoma_LUSC_TCGA-85-7699-01A-11R-2125-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

435 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-85-7699-01A-11R-2125-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ADAMDEC1 ADAM-like, decysin 1
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADGRL2 adhesion G protein-coupled receptor L2
ALDH9A1 aldehyde dehydrogenase 9 family, member A1
ANO1 anoctamin 1, calcium activated chloride channel
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ARHGAP11B Rho GTPase activating protein 11B
ARHGAP35 Rho GTPase activating protein 35
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATAD2 ATPase family, AAA domain containing 2
ATAD5 ATPase family, AAA domain containing 5
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C12ORF4 chromosome 12 open reading frame 4
C17ORF85 chromosome 17 open reading frame 85
C19ORF44 chromosome 19 open reading frame 44
C1ORF112 chromosome 1 open reading frame 112
C5ORF34 chromosome 5 open reading frame 34
CASC5 cancer susceptibility candidate 5
CASP8AP2 caspase 8 associated protein 2
CCAR2 cell cycle and apoptosis regulator 2
CCDC18 coiled-coil domain containing 18
CCDC77 coiled-coil domain containing 77
CCDC88A coiled-coil domain containing 88A
CCDC97 coiled-coil domain containing 97
CCNB2 cyclin B2
CCND1 cyclin D1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR8 chemokine (C-C motif) receptor 8
CD8A CD8a molecule
CDC6 cell division cycle 6
CDC7 cell division cycle 7
CDCA2 cell division cycle associated 2
CDH19 cadherin 19, type 2
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CDK14 cyclin-dependent kinase 14
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CENPF centromere protein F, 350/400kDa
CEP128 centrosomal protein 128kDa
CEP170 centrosomal protein 170kDa
CEP170P1 centrosomal protein 170kDa pseudogene 1
CEP78 centrosomal protein 78kDa
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHD3 chromodomain helicase DNA binding protein 3
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIC capicua transcriptional repressor
CIT citron rho-interacting serine/threonine kinase
CLDN10 claudin 10
CLSPN claspin
COL4A2 collagen, type IV, alpha 2
COL8A2 collagen, type VIII, alpha 2
COL9A1 collagen, type IX, alpha 1
COL9A2 collagen, type IX, alpha 2
COL9A3 collagen, type IX, alpha 3
CSDE1 cold shock domain containing E1, RNA-binding
CSPG4 chondroitin sulfate proteoglycan 4
CSRP2 cysteine and glycine-rich protein 2
CTXN3 cortexin 3
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR3 chemokine (C-X-C motif) receptor 3
DCLRE1B DNA cross-link repair 1B
DHCR7 7-dehydrocholesterol reductase
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DMD dystrophin
DNAH17 dynein, axonemal, heavy chain 17
DNM1L dynamin 1-like
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DPY19L2P2 DPY19L2 pseudogene 2
DPY19L2P4 DPY19L2 pseudogene 4
DRAXIN dorsal inhibitory axon guidance protein
DROSHA drosha, ribonuclease type III
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DZIP1 DAZ interacting zinc finger protein 1
EBF3 early B-cell factor 3
EDAR ectodysplasin A receptor
EFTUD1 elongation factor Tu GTP binding domain containing 1
ENAH enabled homolog (Drosophila)
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2
EOMES eomesodermin
EP400 E1A binding protein p400
EPHB4 EPH receptor B4
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERI1 exoribonuclease 1
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2
ETV6 ets variant 6
EXO1 exonuclease 1
EXOSC10 exosome component 10
EYA3 EYA transcriptional coactivator and phosphatase 3
F5 coagulation factor V (proaccelerin, labile factor)
FADD Fas (TNFRSF6)-associated via death domain
FAIM2 Fas apoptotic inhibitory molecule 2
FAM101A family with sequence similarity 101, member A
FAM155A family with sequence similarity 155, member A
FAM179B family with sequence similarity 179, member B
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
FAM21A family with sequence similarity 21, member A
FAM65C family with sequence similarity 65, member C
FAM98B family with sequence similarity 98, member B
FANCD2 Fanconi anemia, complementation group D2
FANCM Fanconi anemia, complementation group M
FASLG Fas ligand (TNF superfamily, member 6)
FBXO43 F-box protein 43
FGF19 fibroblast growth factor 19
FGF3 fibroblast growth factor 3
FGFR1 fibroblast growth factor receptor 1
FOXC1 forkhead box C1
FOXD4 forkhead box D4
FOXM1 forkhead box M1
FOXP4 forkhead box P4
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FZD9 frizzled class receptor 9
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GINS4 GINS complex subunit 4 (Sld5 homolog)
GJC1 gap junction protein, gamma 1, 45kDa
GLCE glucuronic acid epimerase
GMDS GDP-mannose 4,6-dehydratase
GMEB1 glucocorticoid modulatory element binding protein 1
GPR25 G protein-coupled receptor 25
GRAP2 GRB2-related adaptor protein 2
GRIK1-AS1 GRIK1 antisense RNA 1
GSG2 germ cell associated 2 (haspin)
GTSE1 G-2 and S-phase expressed 1
GUSBP1 glucuronidase, beta pseudogene 1
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
HCG18 HLA complex group 18 (non-protein coding)
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HILS1 histone linker H1 domain, spermatid-specific 1, pseudogene
HMCN1 hemicentin 1
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HSP90AB2P heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ICE1 interactor of little elongation complex ELL subunit 1
ICOSLG inducible T-cell co-stimulator ligand
IFNG interferon, gamma
IL12B interleukin 12B
IL17A interleukin 17A
IL18R1 interleukin 18 receptor 1
IL21 interleukin 21
IL26 interleukin 26
IL27RA interleukin 27 receptor, alpha
IL4I1 interleukin 4 induced 1
IL9R interleukin 9 receptor
ILF3 interleukin enhancer binding factor 3, 90kDa
INTS10 integrator complex subunit 10
INTS7 integrator complex subunit 7
IPO8 importin 8
IRF2BPL interferon regulatory factor 2 binding protein-like
IRX2 iroquois homeobox 2
IRX4 iroquois homeobox 4
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGA9 integrin, alpha 9
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM5A lysine (K)-specific demethylase 5A
KIAA0753 KIAA0753
KIF11 kinesin family member 11
KIF14 kinesin family member 14
KIF15 kinesin family member 15
KIF18B kinesin family member 18B
KIF20B kinesin family member 20B
KIF23 kinesin family member 23
KIF24 kinesin family member 24
KIF2C kinesin family member 2C
KIF4A kinesin family member 4A
KIF4B kinesin family member 4B
KIFC1 kinesin family member C1
KIRREL3 kin of IRRE like 3 (Drosophila)
KPNB1 karyopherin (importin) beta 1
KRT23 keratin 23, type I
LAMA1 laminin, alpha 1
LIG1 ligase I, DNA, ATP-dependent
LINC00028 long intergenic non-protein coding RNA 28
LIPJ lipase, family member J
LMNB1 lamin B1
LOC284661 uncharacterized LOC284661
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRP6 low density lipoprotein receptor-related protein 6
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
LRRN1 leucine rich repeat neuronal 1
LTA lymphotoxin alpha
MAOB monoamine oxidase B
MCM7 minichromosome maintenance complex component 7
MDC1 mediator of DNA-damage checkpoint 1
MDFI MyoD family inhibitor
MDN1 MDN1, midasin homolog (yeast)
MED23 mediator complex subunit 23
MEGF8 multiple EGF-like-domains 8
MIA melanoma inhibitory activity
MIS18A MIS18 kinetochore protein A
MIS18BP1 MIS18 binding protein 1
MIXL1 Mix paired-like homeobox
MKI67 marker of proliferation Ki-67
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MTBP MDM2 binding protein
MTMR12 myotubularin related protein 12
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MURC muscle-related coiled-coil protein
MYBPC1 myosin binding protein C, slow type
MYO10 myosin X
NCAPD2 non-SMC condensin I complex, subunit D2
NCAPH non-SMC condensin I complex, subunit H
NCK2 NCK adaptor protein 2
NCOR1 nuclear receptor corepressor 1
NFIB nuclear factor I/B
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NFYA nuclear transcription factor Y, alpha
NIPBL Nipped-B homolog (Drosophila)
NOL9 nucleolar protein 9
NOTCH1 notch 1
NPTXR neuronal pentraxin receptor
NPVF neuropeptide VF precursor
NPY1R neuropeptide Y receptor Y1
NRF1 nuclear respiratory factor 1
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
NUP133 nucleoporin 133kDa
NUP153 nucleoporin 153kDa
NUP155 nucleoporin 155kDa
NUP62 nucleoporin 62kDa
NUSAP1 nucleolar and spindle associated protein 1
NVL nuclear VCP-like
OBP2A odorant binding protein 2A
ORAOV1 oral cancer overexpressed 1
ORC1 origin recognition complex, subunit 1
OSR1 odd-skipped related transciption factor 1
PADI2 peptidyl arginine deiminase, type II
PALM2 paralemmin 2
PARP11 poly (ADP-ribose) polymerase family, member 11
PCDHA2 protocadherin alpha 2
PCDHGB5 protocadherin gamma subfamily B, 5
PCM1 pericentriolar material 1
PCNT pericentrin
PDCD1 programmed cell death 1
PDCD11 programmed cell death 11
PDCD7 programmed cell death 7
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFA platelet-derived growth factor alpha polypeptide
PFAS phosphoribosylformylglycinamidine synthase
PHC1 polyhomeotic homolog 1 (Drosophila)
PHPT1 phosphohistidine phosphatase 1
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
PLXNA1 plexin A1
PMEPA1 prostate transmembrane protein, androgen induced 1
PNMAL1 paraneoplastic Ma antigen family-like 1
PNMAL2 paraneoplastic Ma antigen family-like 2
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRDM15 PR domain containing 15
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRLR prolactin receptor
PRPF8 pre-mRNA processing factor 8
PRR11 proline rich 11
PRR16 proline rich 16
PRRC2A proline-rich coiled-coil 2A
PTX3 pentraxin 3, long
PUS7 pseudouridylate synthase 7 (putative)
QRICH2 glutamine rich 2
RAD21 RAD21 homolog (S. pombe)
RAD51 RAD51 recombinase
RAD51AP1 RAD51 associated protein 1
RAD51C RAD51 paralog C
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RBM23 RNA binding motif protein 23
RCC2 regulator of chromosome condensation 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
REP15 RAB15 effector protein
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1
RNF150 ring finger protein 150
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF24 ring finger protein 24
ROPN1 rhophilin associated tail protein 1
ROPN1B rhophilin associated tail protein 1B
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPA1 replication protein A1, 70kDa
RPL13AP6 ribosomal protein L13a pseudogene 6
RRP1B ribosomal RNA processing 1B
RTN4RL1 reticulon 4 receptor-like 1
RUNX1 runt-related transcription factor 1
RUNX3 runt-related transcription factor 3
SAE1 SUMO1 activating enzyme subunit 1
SASS6 spindle assembly 6 homolog (C. elegans)
SAV1 salvador family WW domain containing protein 1
SCARB1 scavenger receptor class B, member 1
SELV selenoprotein V
SEPT3 septin 3
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SFMBT2 Scm-like with four mbt domains 2
SFPQ splicing factor proline/glutamine-rich
SFRP1 secreted frizzled-related protein 1
SH3RF3 SH3 domain containing ring finger 3
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHB Src homology 2 domain containing adaptor protein B
SHC4 SHC (Src homology 2 domain containing) family, member 4
SIAH3 siah E3 ubiquitin protein ligase family member 3
SIGLEC10 sialic acid binding Ig-like lectin 10
SIGLEC8 sialic acid binding Ig-like lectin 8
SIKE1 suppressor of IKBKE 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC25A51 solute carrier family 25, member 51
SLCO5A1 solute carrier organic anion transporter family, member 5A1
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
SMC1A structural maintenance of chromosomes 1A
SMC2 structural maintenance of chromosomes 2
SMC5 structural maintenance of chromosomes 5
SMG9 SMG9 nonsense mediated mRNA decay factor
SMYD4 SET and MYND domain containing 4
SNORA61 small nucleolar RNA, H/ACA box 61
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5)
SON SON DNA binding protein
SOX10 SRY (sex determining region Y)-box 10
SOX4 SRY (sex determining region Y)-box 4
SOX9 SRY (sex determining region Y)-box 9
SP6 Sp6 transcription factor
SPHK2 sphingosine kinase 2
SRR serine racemase
SSBP3 single stranded DNA binding protein 3
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIL SCL/TAL1 interrupting locus
STK38L serine/threonine kinase 38 like
STRIP1 striatin interacting protein 1
SUMO3 small ubiquitin-like modifier 3
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
SYNM synemin, intermediate filament protein
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
TCF12 transcription factor 12
TCTN2 tectonic family member 2
TICRR TOPBP1-interacting checkpoint and replication regulator
TIFAB TRAF-interacting protein with forkhead-associated domain, family member B
TLE3 transducin-like enhancer of split 3
TMEM151B transmembrane protein 151B
TMEM181 transmembrane protein 181
TMEM39B transmembrane protein 39B
TMEM86B transmembrane protein 86B
TMPO thymopoietin
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TOP2A topoisomerase (DNA) II alpha 170kDa
TP73 tumor protein p73
TPR translocated promoter region, nuclear basket protein
TRAF2 TNF receptor-associated factor 2
TRAF3IP3 TRAF3 interacting protein 3
TRPS1 trichorhinophalangeal syndrome I
TTC3 tetratricopeptide repeat domain 3
TTLL5 tubulin tyrosine ligase-like family member 5
TYMS thymidylate synthetase
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
UBTF upstream binding transcription factor, RNA polymerase I
UHRF1 ubiquitin-like with PHD and ring finger domains 1
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VASH2 vasohibin 2
VGLL4 vestigial-like family member 4
VRK3 vaccinia related kinase 3
WBP11 WW domain binding protein 11
WBP11P1 WW domain binding protein 11 pseudogene 1
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR70 WD repeat domain 70
WHAMMP2 WAS protein homolog associated with actin, golgi membranes and microtubules pseudogene 2
WRAP53 WD repeat containing, antisense to TP53
WRN Werner syndrome, RecQ helicase-like
WTIP Wilms tumor 1 interacting protein
XIRP1 xin actin binding repeat containing 1
XKR5 XK, Kell blood group complex subunit-related family, member 5
XPO7 exportin 7
ZBTB24 zinc finger and BTB domain containing 24
ZCCHC5 zinc finger, CCHC domain containing 5
ZFR zinc finger RNA binding protein
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZMYM4 zinc finger, MYM-type 4
ZNF106 zinc finger protein 106
ZNF112 zinc finger protein 112
ZNF131 zinc finger protein 131
ZNF175 zinc finger protein 175
ZNF180 zinc finger protein 180
ZNF221 zinc finger protein 221
ZNF225 zinc finger protein 225
ZNF227 zinc finger protein 227
ZNF230 zinc finger protein 230
ZNF234 zinc finger protein 234
ZNF253 zinc finger protein 253
ZNF264 zinc finger protein 264
ZNF286A zinc finger protein 286A
ZNF30 zinc finger protein 30
ZNF326 zinc finger protein 326
ZNF329 zinc finger protein 329
ZNF347 zinc finger protein 347
ZNF391 zinc finger protein 391
ZNF407 zinc finger protein 407
ZNF419 zinc finger protein 419
ZNF428 zinc finger protein 428
ZNF45 zinc finger protein 45
ZNF470 zinc finger protein 470
ZNF473 zinc finger protein 473
ZNF496 zinc finger protein 496
ZNF497 zinc finger protein 497
ZNF521 zinc finger protein 521
ZNF530 zinc finger protein 530
ZNF547 zinc finger protein 547
ZNF549 zinc finger protein 549
ZNF569 zinc finger protein 569
ZNF594 zinc finger protein 594
ZNF615 zinc finger protein 615
ZNF618 zinc finger protein 618
ZNF678 zinc finger protein 678
ZNF749 zinc finger protein 749
ZNF773 zinc finger protein 773
ZNF8 zinc finger protein 8
ZNF84 zinc finger protein 84
ZSCAN22 zinc finger and SCAN domain containing 22
ZSCAN5A zinc finger and SCAN domain containing 5A
ZWILCH zwilch kinetochore protein