Lung squamous cell carcinoma_LUSC_TCGA-77-A5GB-01B-11R-A27Q-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

382 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-77-A5GB-01B-11R-A27Q-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ABLIM2 actin binding LIM protein family, member 2
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4
AGAP5 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5
AIM1L absent in melanoma 1-like
AKIP1 A kinase (PRKA) interacting protein 1
AKR7A2P1 aldo-keto reductase family 7, member A2 pseudogene 1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARFRP1 ADP-ribosylation factor related protein 1
ARHGEF37 Rho guanine nucleotide exchange factor (GEF) 37
ARPC5L actin related protein 2/3 complex, subunit 5-like
ATG16L2 autophagy related 16-like 2 (S. cerevisiae)
ATP13A2 ATPase type 13A2
B3GALTL beta 1,3-galactosyltransferase-like
BICD2 bicaudal D homolog 2 (Drosophila)
BMP2 bone morphogenetic protein 2
BMS1 BMS1 ribosome biogenesis factor
BNC1 basonuclin 1
C10ORF55 chromosome 10 open reading frame 55
C11ORF42 chromosome 11 open reading frame 42
C19ORF18 chromosome 19 open reading frame 18
C1ORF68 chromosome 1 open reading frame 68
C1ORF74 chromosome 1 open reading frame 74
C20ORF197 chromosome 20 open reading frame 197
C2CD4C C2 calcium-dependent domain containing 4C
C2ORF80 chromosome 2 open reading frame 80
C9ORF40 chromosome 9 open reading frame 40
CA2 carbonic anhydrase II
CARD10 caspase recruitment domain family, member 10
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CCDC15 coiled-coil domain containing 15
CCDC18 coiled-coil domain containing 18
CCDC93 coiled-coil domain containing 93
CCHCR1 coiled-coil alpha-helical rod protein 1
CCL27 chemokine (C-C motif) ligand 27
CCM2 cerebral cavernous malformation 2
CCNE1 cyclin E1
CCNE2 cyclin E2
CDC16 cell division cycle 16
CDC25B cell division cycle 25B
CDC37 cell division cycle 37
CDCA7 cell division cycle associated 7
CDH16 cadherin 16, KSP-cadherin
CDHR1 cadherin-related family member 1
CDK1 cyclin-dependent kinase 1
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDRT15P1 CMT1A duplicated region transcript 15 pseudogene 1
CEACAM19 carcinoembryonic antigen-related cell adhesion molecule 19
CENPP centromere protein P
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
CLLU1 chronic lymphocytic leukemia up-regulated 1
CLSPN claspin
CNGB1 cyclic nucleotide gated channel beta 1
CNIH2 cornichon family AMPA receptor auxiliary protein 2
CNTFR ciliary neurotrophic factor receptor
COL12A1 collagen, type XII, alpha 1
COL13A1 collagen, type XIII, alpha 1
COL5A3 collagen, type V, alpha 3
CORO6 coronin 6
CRCP CGRP receptor component
CRCT1 cysteine-rich C-terminal 1
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CTSV cathepsin V
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
CXCL14 chemokine (C-X-C motif) ligand 14
CYB5R1 cytochrome b5 reductase 1
CYCSP52 cytochrome c, somatic pseudogene 52
CYP27C1 cytochrome P450, family 27, subfamily C, polypeptide 1
DAGLB diacylglycerol lipase, beta
DAND5 DAN domain family member 5, BMP antagonist
DAPK3 death-associated protein kinase 3
DBF4 DBF4 zinc finger
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DFNA5 deafness, autosomal dominant 5
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6
DIRAS1 DIRAS family, GTP-binding RAS-like 1
DIRC1 disrupted in renal carcinoma 1
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNAH17 dynein, axonemal, heavy chain 17
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DOHH deoxyhypusine hydroxylase/monooxygenase
DONSON downstream neighbor of SON
DOT1L DOT1-like histone H3K79 methyltransferase
DSC2 desmocollin 2
DSC3 desmocollin 3
DSG1 desmoglein 1
DSP desmoplakin
DTX2 deltex 2, E3 ubiquitin ligase
DUS2 dihydrouridine synthase 2
DZIP1L DAZ interacting zinc finger protein 1-like
E2F2 E2F transcription factor 2
E2F8 E2F transcription factor 8
ECD ecdysoneless homolog (Drosophila)
EIF3IP1 eukaryotic translation initiation factor 3, subunit I pseudogene 1
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EIF4H eukaryotic translation initiation factor 4H
ELL elongation factor RNA polymerase II
EPHA8 EPH receptor A8
ERCC6 excision repair cross-complementation group 6
FAM111B family with sequence similarity 111, member B
FAM205A family with sequence similarity 205, member A
FAM205BP transmembrane protein C9orf144B pseudogene
FAM20C family with sequence similarity 20, member C
FAM213A family with sequence similarity 213, member A
FAM72D family with sequence similarity 72, member D
FAM83B family with sequence similarity 83, member B
FBLIM1 filamin binding LIM protein 1
FBXL18 F-box and leucine-rich repeat protein 18
FBXL6 F-box and leucine-rich repeat protein 6
FBXO42 F-box protein 42
FBXO46 F-box protein 46
FERMT1 fermitin family member 1
FGF16 fibroblast growth factor 16
FGFBP1 fibroblast growth factor binding protein 1
FLNB filamin B, beta
FSCN1 fascin actin-bundling protein 1
FSD2 fibronectin type III and SPRY domain containing 2
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GANC glucosidase, alpha; neutral C
GJB2 gap junction protein, beta 2, 26kDa
GJB3 gap junction protein, beta 3, 31kDa
GJB6 gap junction protein, beta 6, 30kDa
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GPR153 G protein-coupled receptor 153
GPR52 G protein-coupled receptor 52
GPR68 G protein-coupled receptor 68
GPRIN1 G protein regulated inducer of neurite outgrowth 1
GPSM2 G-protein signaling modulator 2
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIP2 glutamate receptor interacting protein 2
GSDMC gasdermin C
HAUS2 HAUS augmin-like complex, subunit 2
HCG26 HLA complex group 26 (non-protein coding)
HEPHL1 hephaestin-like 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HES2 hes family bHLH transcription factor 2
HHLA3 HERV-H LTR-associating 3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOMER2 homer scaffolding protein 2
HOMER3 homer scaffolding protein 3
ICMT isoprenylcysteine carboxyl methyltransferase
IFFO2 intermediate filament family orphan 2
IFNLR1 interferon, lambda receptor 1
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1
IL12RB2 interleukin 12 receptor, beta 2
IL20 interleukin 20
IL20RB interleukin 20 receptor beta
IL22RA1 interleukin 22 receptor, alpha 1
IL36G interleukin 36, gamma
INGX inhibitor of growth family, X-linked, pseudogene
INHBA inhibin, beta A
INTS4P2 integrator complex subunit 4 pseudogene 2
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF6 interferon regulatory factor 6
IVL involucrin
JAG1 jagged 1
JARID2 jumonji, AT rich interactive domain 2
KATNAL1 katanin p60 subunit A-like 1
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNK10 potassium channel, two pore domain subfamily K, member 10
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KIAA1644 KIAA1644
KIFC3 kinesin family member C3
KLHL17 kelch-like family member 17
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT6B keratin 6B, type II
KRT6C keratin 6C, type II
KRT82 keratin 82, type II
KRTAP11-1 keratin associated protein 11-1
KRTAP13-1 keratin associated protein 13-1
KRTAP13-2 keratin associated protein 13-2
LAD1 ladinin 1
LCAT lecithin-cholesterol acyltransferase
LCE3D late cornified envelope 3D
LCE3E late cornified envelope 3E
LGALS7B lectin, galactoside-binding, soluble, 7B
LINC00174 long intergenic non-protein coding RNA 174
LINC00202-1 long intergenic non-protein coding RNA 202-1
LMNB2 lamin B2
LOC100130264 uncharacterized LOC100130264
LOC493754
LOC91450 uncharacterized LOC91450
LRRC74A leucine rich repeat containing 74A
LTB4R leukotriene B4 receptor
LTB4R2 leukotriene B4 receptor 2
LUZP1 leucine zipper protein 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MCU mitochondrial calcium uniporter
MDFI MyoD family inhibitor
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2
MFSD12 major facilitator superfamily domain containing 12
MIER2 mesoderm induction early response 1, family member 2
MIR17HG miR-17-92 cluster host gene
MMP1 matrix metallopeptidase 1
MMP23A matrix metallopeptidase 23A (pseudogene)
MMP3 matrix metallopeptidase 3
MOB2 MOB kinase activator 2
MOB3A MOB kinase activator 3A
MOGAT2 monoacylglycerol O-acyltransferase 2
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRGPRX3 MAS-related GPR, member X3
MRI1 methylthioribose-1-phosphate isomerase 1
MRPS16 mitochondrial ribosomal protein S16
MYOM3 myomesin 3
NAP1L4 nucleosome assembly protein 1-like 4
NES nestin
NLRX1 NLR family member X1
NOD2 nucleotide-binding oligomerization domain containing 2
NOTO notochord homeobox
NPAS4 neuronal PAS domain protein 4
NRBF2 nuclear receptor binding factor 2
NXF1 nuclear RNA export factor 1
OCM2 oncomodulin 2
OLFM2 olfactomedin 2
OR2C1 olfactory receptor, family 2, subfamily C, member 1
OR5C1 olfactory receptor, family 5, subfamily C, member 1
OSBPL3 oxysterol binding protein-like 3
PANX1 pannexin 1
PAQR4 progestin and adipoQ receptor family member IV
PARG poly (ADP-ribose) glycohydrolase
PARP2 poly (ADP-ribose) polymerase 2
PCDHB6 protocadherin beta 6
PCDHGC5 protocadherin gamma subfamily C, 5
PDDC1 Parkinson disease 7 domain containing 1
PDPN podoplanin
PERM1 PPARGC1 and ESRR induced regulator, muscle 1
PEX5 peroxisomal biogenesis factor 5
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PGBD3 piggyBac transposable element derived 3
PGLYRP4 peptidoglycan recognition protein 4
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIP5KL1 phosphatidylinositol-4-phosphate 5-kinase-like 1
PKLR pyruvate kinase, liver and RBC
PKP1 plakophilin 1
PKP3 plakophilin 3
PLAU plasminogen activator, urokinase
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLEKHN1 pleckstrin homology domain containing, family N member 1
PLIN3 perilipin 3
PMFBP1 polyamine modulated factor 1 binding protein 1
PNP purine nucleoside phosphorylase
PNPLA3 patatin-like phospholipase domain containing 3
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
POU3F1 POU class 3 homeobox 1
PPAN peter pan homolog (Drosophila)
PPARD peroxisome proliferator-activated receptor delta
PPIF peptidylprolyl isomerase F
PPP1R18 protein phosphatase 1, regulatory subunit 18
PQLC1 PQ loop repeat containing 1
PRIMA1 proline rich membrane anchor 1
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTGDR prostaglandin D2 receptor (DP)
PTGFRN prostaglandin F2 receptor inhibitor
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
QTRT1 queuine tRNA-ribosyltransferase 1
R3HDM4 R3H domain containing 4
RAB38 RAB38, member RAS oncogene family
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RALBP1 ralA binding protein 1
RBAK RB-associated KRAB zinc finger
RCAN1 regulator of calcineurin 1
REEP3 receptor accessory protein 3
RELT RELT tumor necrosis factor receptor
REP15 RAB15 effector protein
RIC8A RIC8 guanine nucleotide exchange factor A
RIMS3 regulating synaptic membrane exocytosis 3
RIN1 Ras and Rab interactor 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF152 ring finger protein 152
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPLP0P2 ribosomal protein, large, P0 pseudogene 2
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RRM1 ribonucleotide reductase M1
RTEL1 regulator of telomere elongation helicase 1
S100A7A S100 calcium binding protein A7A
SAMD1 sterile alpha motif domain containing 1
SAR1A secretion associated, Ras related GTPase 1A
SBNO2 strawberry notch homolog 2 (Drosophila)
SCN4B sodium channel, voltage gated, type IV beta subunit
SCO2 SCO2 cytochrome c oxidase assembly protein
SEC24C SEC24 family member C
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SF3A2 splicing factor 3a, subunit 2, 66kDa
SFN stratifin
SH2D5 SH2 domain containing 5
SH3D21 SH3 domain containing 21
SH3GL1 SH3-domain GRB2-like 1
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SIRT3 sirtuin 3
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC17A1 solute carrier family 17 (organic anion transporter), member 1
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2
SLC25A27 solute carrier family 25, member 27
SLC25A40 solute carrier family 25, member 40
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC39A12 solute carrier family 39 (zinc transporter), member 12
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMTN smoothelin
SMYD2 SET and MYND domain containing 2
SNAI2 snail family zinc finger 2
SNX13 sorting nexin 13
SPHK1 sphingosine kinase 1
SPINK6 serine peptidase inhibitor, Kazal type 6
SPRR2G small proline-rich protein 2G
ST5 suppression of tumorigenicity 5
SULT4A1 sulfotransferase family 4A, member 1
SYT7 synaptotagmin VII
TARDBP TAR DNA binding protein
TCF19 transcription factor 19
TEAD4 TEA domain family member 4
TEX29 testis expressed 29
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFBI transforming growth factor, beta-induced, 68kDa
TICAM1 toll-like receptor adaptor molecule 1
TICAM2 toll-like receptor adaptor molecule 2
TM4SF19 transmembrane 4 L six family member 19
TMEM254 transmembrane protein 254
TMEM255B transmembrane protein 255B
TMOD4 tropomodulin 4 (muscle)
TNFAIP8L3 tumor necrosis factor, alpha-induced protein 8-like 3
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNKS1BP1 tankyrase 1 binding protein 1, 182kDa
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1
TPM4 tropomyosin 4
TRIP10 thyroid hormone receptor interactor 10
TTLL13P tubulin tyrosine ligase-like family member 13, pseudogene
TTPAL tocopherol (alpha) transfer protein-like
TUBB6 tubulin, beta 6 class V
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UHRF1 ubiquitin-like with PHD and ring finger domains 1
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VAV2 vav 2 guanine nucleotide exchange factor
VCL vinculin
VDAC2 voltage-dependent anion channel 2
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
WASH5P WAS protein family homolog 5 pseudogene
WDFY2 WD repeat and FYVE domain containing 2
WFDC10A WAP four-disulfide core domain 10A
WFDC5 WAP four-disulfide core domain 5
WRNIP1 Werner helicase interacting protein 1
YOD1 YOD1 deubiquitinase
ZBTB17 zinc finger and BTB domain containing 17
ZBTB43 zinc finger and BTB domain containing 43
ZFAT-AS1 ZFAT antisense RNA 1
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate)
ZGLP1 zinc finger, GATA-like protein 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF133 zinc finger protein 133
ZNF33A zinc finger protein 33A
ZNF37A zinc finger protein 37A
ZNF700 zinc finger protein 700
ZNF846 zinc finger protein 846
ZNF878 zinc finger protein 878
ZP1 zona pellucida glycoprotein 1 (sperm receptor)
ZSWIM8 zinc finger, SWIM-type containing 8
ZWINT ZW10 interacting kinetochore protein

low expression

Symbol Name
DCAF7 DDB1 and CUL4 associated factor 7
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like
KCTD3 potassium channel tetramerization domain containing 3
MFSD11 major facilitator superfamily domain containing 11
USP9X ubiquitin specific peptidase 9, X-linked