Lung squamous cell carcinoma_LUSC_TCGA-77-8146-01A-11R-2247-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

325 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-77-8146-01A-11R-2247-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACADVL acyl-CoA dehydrogenase, very long chain
ACP6 acid phosphatase 6, lysophosphatidic
ACSL3 acyl-CoA synthetase long-chain family member 3
ADAM28 ADAM metallopeptidase domain 28
ADAM9 ADAM metallopeptidase domain 9
ADGRG1 adhesion G protein-coupled receptor G1
AGRN agrin
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDOA aldolase A, fructose-bisphosphate
AMIGO2 adhesion molecule with Ig-like domain 2
ANKK1 ankyrin repeat and kinase domain containing 1
ANKRD11 ankyrin repeat domain 11
ANP32A-IT1 ANP32A intronic transcript 1
ANXA2 annexin A2
ANXA2P2 annexin A2 pseudogene 2
APLP2 amyloid beta (A4) precursor-like protein 2
ARHGAP32 Rho GTPase activating protein 32
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
BBC3 BCL2 binding component 3
BCAM basal cell adhesion molecule (Lutheran blood group)
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BID BH3 interacting domain death agonist
BIN3 bridging integrator 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C16ORF13 chromosome 16 open reading frame 13
C16ORF62 chromosome 16 open reading frame 62
C1RL complement component 1, r subcomponent-like
C22ORF39 chromosome 22 open reading frame 39
C3ORF79 chromosome 3 open reading frame 79
C8ORF58 chromosome 8 open reading frame 58
CA7 carbonic anhydrase VII
CABP4 calcium binding protein 4
CALB2 calbindin 2
CAPN2 calpain 2, (m/II) large subunit
CAT catalase
CCAR2 cell cycle and apoptosis regulator 2
CCDC64B coiled-coil domain containing 64B
CCDC9 coiled-coil domain containing 9
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CD276 CD276 molecule
CDH26 cadherin 26
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK10 cyclin-dependent kinase 10
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CECR1 cat eye syndrome chromosome region, candidate 1
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CFAP44 cilia and flagella associated protein 44
CFH complement factor H
CFHR1 complement factor H-related 1
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
CIB1 calcium and integrin binding 1 (calmyrin)
CIB3 calcium and integrin binding family member 3
CLEC18A C-type lectin domain family 18, member A
CLEC18B C-type lectin domain family 18, member B
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CMBL carboxymethylenebutenolidase homolog (Pseudomonas)
CMTM8 CKLF-like MARVEL transmembrane domain containing 8
CNTN3 contactin 3 (plasmacytoma associated)
COL7A1 collagen, type VII, alpha 1
COMT catechol-O-methyltransferase
CPD carboxypeptidase D
CRELD1 cysteine-rich with EGF-like domains 1
CRIP2 cysteine-rich protein 2
CTSC cathepsin C
CX3CL1 chemokine (C-X3-C motif) ligand 1
D2HGDH D-2-hydroxyglutarate dehydrogenase
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCTN6 dynactin 6
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DGCR14 DiGeorge syndrome critical region gene 14
DGCR2 DiGeorge syndrome critical region gene 2
DHRS9 dehydrogenase/reductase (SDR family) member 9
DMTN dematin actin binding protein
DOCK5 dedicator of cytokinesis 5
DPP10 dipeptidyl-peptidase 10 (non-functional)
EHBP1L1 EH domain binding protein 1-like 1
ELMO3 engulfment and cell motility 3
ELP3 elongator acetyltransferase complex subunit 3
EME2 essential meiotic structure-specific endonuclease subunit 2
EML3 echinoderm microtubule associated protein like 3
ENDOD1 endonuclease domain containing 1
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
ERICH1 glutamate-rich 1
ERMP1 endoplasmic reticulum metallopeptidase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EXTL3 exostosin-like glycosyltransferase 3
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM131B family with sequence similarity 131, member B
FAM138E family with sequence similarity 138, member E
FAM160B2 family with sequence similarity 160, member B2
FAM173A family with sequence similarity 173, member A
FAM95B1 family with sequence similarity 95, member B1
FBLIM1 filamin binding LIM protein 1
FBXL8 F-box and leucine-rich repeat protein 8
FKRP fukutin related protein
FLJ23867 uncharacterized protein FLJ23867
FLRT2 fibronectin leucine rich transmembrane protein 2
FOXL1 forkhead box L1
FRMD5 FERM domain containing 5
FSCN2 fascin actin-bundling protein 2, retinal
G6PD glucose-6-phosphate dehydrogenase
GAA glucosidase, alpha; acid
GALE UDP-galactose-4-epimerase
GALNS galactosamine (N-acetyl)-6-sulfatase
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GANAB glucosidase, alpha; neutral AB
GAS8-AS1 GAS8 antisense RNA 1
GDAP2 ganglioside induced differentiation associated protein 2
GDF15 growth differentiation factor 15
GDNF glial cell derived neurotrophic factor
GLIPR1L1 GLI pathogenesis-related 1 like 1
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPC1 glypican 1
GSR glutathione reductase
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa
GUCY2F guanylate cyclase 2F, retinal
GYLTL1B glycosyltransferase-like 1B
HIRA histone cell cycle regulator
HIST3H3 histone cluster 3, H3
HP haptoglobin
HPYR1 Helicobacter pylori responsive 1 (non-protein coding)
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSF4 heat shock transcription factor 4
IER5L immediate early response 5-like
IFITM4P interferon induced transmembrane protein 4 pseudogene
IL17RA interleukin 17 receptor A
ILDR1 immunoglobulin-like domain containing receptor 1
INTS9 integrator complex subunit 9
IRS1 insulin receptor substrate 1
ITFG3 integrin alpha FG-GAP repeat containing 3
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB6 integrin, beta 6
JMJD8 jumonji domain containing 8
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7
KIAA0895L KIAA0895-like
KLHDC7A kelch domain containing 7A
KRTAP5-1 keratin associated protein 5-1
KRTAP9-4 keratin associated protein 9-4
LAMA3 laminin, alpha 3
LAMA5 laminin, alpha 5
LINC00521 long intergenic non-protein coding RNA 521
LOC100134368 uncharacterized LOC100134368
LOC284788 uncharacterized LOC284788
LOC388242 coiled-coil domain containing 101 pseudogene
LOC91450 uncharacterized LOC91450
LSR lipolysis stimulated lipoprotein receptor
LTBP3 latent transforming growth factor beta binding protein 3
LZTS2 leucine zipper, putative tumor suppressor 2
MAN2C1 mannosidase, alpha, class 2C, member 1
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1
MED15 mediator complex subunit 15
MESDC1 mesoderm development candidate 1
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MISP mitotic spindle positioning
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRPL40 mitochondrial ribosomal protein L40
MRPL42P5 mitochondrial ribosomal protein L42 pseudogene 5
MST1R macrophage stimulating 1 receptor
MT1B metallothionein 1B
MTHFSD methenyltetrahydrofolate synthetase domain containing
MUC16 mucin 16, cell surface associated
MVK mevalonate kinase
MYO5C myosin VC
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NELL1 NEL-like 1 (chicken)
NKX1-2 NK1 homeobox 2
NMB neuromedin B
NME3 NME/NM23 nucleoside diphosphate kinase 3
NME4 NME/NM23 nucleoside diphosphate kinase 4
NODAL nodal growth differentiation factor
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NPM2 nucleophosmin/nucleoplasmin 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NR2F6 nuclear receptor subfamily 2, group F, member 6
NRG1 neuregulin 1
NTN1 netrin 1
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NXNL1 nucleoredoxin-like 1
OR10A6 olfactory receptor, family 10, subfamily A, member 6 (gene/pseudogene)
ORAI3 ORAI calcium release-activated calcium modulator 3
PBLD phenazine biosynthesis-like protein domain containing
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH20 protocadherin 20
PCDHGB8P protocadherin gamma subfamily B, 8 pseudogene
PDIA3 protein disulfide isomerase family A, member 3
PDIA3P1 protein disulfide isomerase family A, member 3 pseudogene 1
PDLIM7 PDZ and LIM domain 7 (enigma)
PEX26 peroxisomal biogenesis factor 26
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PKD2L2 polycystic kidney disease 2-like 2
PKM pyruvate kinase, muscle
PLAT plasminogen activator, tissue
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
PLS1 plastin 1
PLXNB1 plexin B1
PNKP polynucleotide kinase 3'-phosphatase
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POM121L8P POM121 transmembrane nucleoporin-like 8 pseudogene
POU5F2 POU domain class 5, transcription factor 2
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PRDM8 PR domain containing 8
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRO0628 uncharacterized LOC29053
PRR15 proline rich 15
PRSS1 protease, serine, 1 (trypsin 1)
PRSS3P2 protease, serine, 3 pseudogene 2
PRSS8 protease, serine, 8
PSD3 pleckstrin and Sec7 domain containing 3
PTGFRN prostaglandin F2 receptor inhibitor
PTK2B protein tyrosine kinase 2 beta
PTK6 protein tyrosine kinase 6
PXN paxillin
PYROXD2 pyridine nucleotide-disulphide oxidoreductase domain 2
R3HCC1 R3H domain and coiled-coil containing 1
RAB26 RAB26, member RAS oncogene family
RAB40C RAB40C, member RAS oncogene family
RAI1 retinoic acid induced 1
REEP4 receptor accessory protein 4
RGL3 ral guanine nucleotide dissociation stimulator-like 3
RGS17 regulator of G-protein signaling 17
RGS21 regulator of G-protein signaling 21
RGS7BP regulator of G-protein signaling 7 binding protein
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHBDL1 rhomboid, veinlet-like 1 (Drosophila)
RHOT2 ras homolog family member T2
RICTOR RPTOR independent companion of MTOR, complex 2
ROGDI rogdi homolog (Drosophila)
RRN3P3 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 3
SCARA3 scavenger receptor class A, member 3
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SEPT5 septin 5
SERINC4 serine incorporator 4
SGK223 homolog of rat pragma of Rnd2
SGSH N-sulfoglucosamine sulfohydrolase
SGSM2 small G protein signaling modulator 2
SIDT1 SID1 transmembrane family, member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC2A4RG SLC2A4 regulator
SLC35G5 solute carrier family 35, member G5
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC7A5P2 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2
SLITRK6 SLIT and NTRK-like family, member 6
SLX1B SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
SNAP29 synaptosomal-associated protein, 29kDa
SNORA15 small nucleolar RNA, H/ACA box 15
SORBS3 sorbin and SH3 domain containing 3
SPACA4 sperm acrosome associated 4
SPATA20 spermatogenesis associated 20
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SPTSSB serine palmitoyltransferase, small subunit B
SSC4D scavenger receptor cysteine rich family, 4 domains
SSH3 slingshot protein phosphatase 3
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
ST7-AS2 ST7 antisense RNA 2
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STRA6 stimulated by retinoic acid 6
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
STX1A syntaxin 1A (brain)
STX6 syntaxin 6
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
SUMF1 sulfatase modifying factor 1
SYCE1 synaptonemal complex central element protein 1
TAS2R16 taste receptor, type 2, member 16
TAS2R31 taste receptor, type 2, member 31
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMC4 transmembrane channel-like 4
TMC7 transmembrane channel-like 7
TMEM132A transmembrane protein 132A
TMEM184A transmembrane protein 184A
TMEM8A transmembrane protein 8A
TMOD3 tropomodulin 3 (ubiquitous)
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TOR4A torsin family 4, member A
TPRXL tetra-peptide repeat homeobox-like
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRADD TNFRSF1A-associated via death domain
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TSKU tsukushi, small leucine rich proteoglycan
TSPAN1 tetraspanin 1
TTTY10 testis-specific transcript, Y-linked 10 (non-protein coding)
TUBB3 tubulin, beta 3 class III
TUSC3 tumor suppressor candidate 3
TXNRD2 thioredoxin reductase 2
UBE3B ubiquitin protein ligase E3B
UNKL unkempt family zinc finger-like
VASP vasodilator-stimulated phosphoprotein
VHLL von Hippel-Lindau tumor suppressor-like
VILL villin-like
WNT3A wingless-type MMTV integration site family, member 3A
WNT9A wingless-type MMTV integration site family, member 9A
WWTR1 WW domain containing transcription regulator 1
ZDHHC7 zinc finger, DHHC-type containing 7
ZDHHC8 zinc finger, DHHC-type containing 8
ZNF395 zinc finger protein 395
ZNF516 zinc finger protein 516
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase

low expression

Symbol Name
LRIF1 ligand dependent nuclear receptor interacting factor 1