Lung squamous cell carcinoma_LUSC_TCGA-77-8128-01A-11R-2247-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

404 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-77-8128-01A-11R-2247-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AAA1 aortic aneurysm, familial abdominal 1
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ABHD15 abhydrolase domain containing 15
ACO1 aconitase 1, soluble
ACRBP acrosin binding protein
ACVR2B activin A receptor, type IIB
ADRBK2 adrenergic, beta, receptor kinase 2
ADSS adenylosuccinate synthase
AKR1C2 aldo-keto reductase family 1, member C2
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
ALG3 ALG3, alpha-1,3- mannosyltransferase
ANKRD13B ankyrin repeat domain 13B
ANKRD35 ankyrin repeat domain 35
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
APTX aprataxin
ARHGEF39 Rho guanine nucleotide exchange factor (GEF) 39
ASCL2 achaete-scute family bHLH transcription factor 2
ASPHD2 aspartate beta-hydroxylase domain containing 2
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
ATRNL1 attractin-like 1
B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BAG1 BCL2-associated athanogene
BAIAP2 BAI1-associated protein 2
BAIAP2L2 BAI1-associated protein 2-like 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BCL7A B-cell CLL/lymphoma 7A
BCORL1 BCL6 corepressor-like 1
BDNF brain-derived neurotrophic factor
BEND4 BEN domain containing 4
BLMH bleomycin hydrolase
BRAT1 BRCA1-associated ATM activator 1
C10ORF90 chromosome 10 open reading frame 90
C11ORF87 chromosome 11 open reading frame 87
C12ORF75 chromosome 12 open reading frame 75
C17ORF82 chromosome 17 open reading frame 82
C19ORF47 chromosome 19 open reading frame 47
C21ORF91 chromosome 21 open reading frame 91
C22ORF31 chromosome 22 open reading frame 31
C9ORF72 chromosome 9 open reading frame 72
CAAP1 caspase activity and apoptosis inhibitor 1
CABIN1 calcineurin binding protein 1
CALB1 calbindin 1, 28kDa
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
CCDC117 coiled-coil domain containing 117
CCDC136 coiled-coil domain containing 136
CCDC177 coiled-coil domain containing 177
CCDC38 coiled-coil domain containing 38
CCDC86 coiled-coil domain containing 86
CCND2 cyclin D2
CDC25A cell division cycle 25A
CDC45 cell division cycle 45
CDH13 cadherin 13
CDHR1 cadherin-related family member 1
CECR5 cat eye syndrome chromosome region, candidate 5
CECR6 cat eye syndrome chromosome region, candidate 6
CHEK2 checkpoint kinase 2
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLCN2 chloride channel, voltage-sensitive 2
CLTA clathrin, light chain A
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNTFR ciliary neurotrophic factor receptor
CNTNAP2 contactin associated protein-like 2
COL10A1 collagen, type X, alpha 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CORIN corin, serine peptidase
CPA2 carboxypeptidase A2 (pancreatic)
CRMP1 collapsin response mediator protein 1
CRYBB3 crystallin, beta B3
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DACT2 dishevelled-binding antagonist of beta-catenin 2
DCAF12 DDB1 and CUL4 associated factor 12
DDT D-dopachrome tautomerase
DDTL D-dopachrome tautomerase-like
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEGS1 delta(4)-desaturase, sphingolipid 1
DEPDC5 DEP domain containing 5
DGCR14 DiGeorge syndrome critical region gene 14
DGCR6L DiGeorge syndrome critical region gene 6-like
DGKE diacylglycerol kinase, epsilon 64kDa
DHFR dihydrofolate reductase
DISC1 disrupted in schizophrenia 1
DLX5 distal-less homeobox 5
DMRT1 doublesex and mab-3 related transcription factor 1
DMRT3 doublesex and mab-3 related transcription factor 3
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11
DNAJB7 DnaJ (Hsp40) homolog, subfamily B, member 7
DOCK3 dedicator of cytokinesis 3
DUSP19 dual specificity phosphatase 19
DVL3 dishevelled segment polarity protein 3
DYNLT3 dynein, light chain, Tctex-type 3
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EFCAB3 EF-hand calcium binding domain 3
EID2 EP300 interacting inhibitor of differentiation 2
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EMILIN3 elastin microfibril interfacer 3
EML1 echinoderm microtubule associated protein like 1
EMX1 empty spiracles homeobox 1
EN2 engrailed homeobox 2
ENHO energy homeostasis associated
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPHB3 EPH receptor B3
EXOSC7 exosome component 7
FADS6 fatty acid desaturase 6
FAM117B family with sequence similarity 117, member B
FAM131A family with sequence similarity 131, member A
FAM167A-AS1 FAM167A antisense RNA 1
FAM184B family with sequence similarity 184, member B
FAM213A family with sequence similarity 213, member A
FAM214B family with sequence similarity 214, member B
FAM219A family with sequence similarity 219, member A
FAM226B family with sequence similarity 226, member B (non-protein coding)
FANCG Fanconi anemia, complementation group G
FAXC failed axon connections homolog (Drosophila)
FBL fibrillarin
FBN2 fibrillin 2
FBRSL1 fibrosin-like 1
FBXO7 F-box protein 7
FEZF1 FEZ family zinc finger 1
FGD1 FYVE, RhoGEF and PH domain containing 1
FGFR2 fibroblast growth factor receptor 2
FOLH1B folate hydrolase 1B
FOXD1 forkhead box D1
FOXE1 forkhead box E1
FOXP2 forkhead box P2
FSTL4 follistatin-like 4
FZD10 frizzled class receptor 10
FZD7 frizzled class receptor 7
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAL galanin/GMAP prepropeptide
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13
GAS2L1 growth arrest-specific 2 like 1
GDF11 growth differentiation factor 11
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJC1 gap junction protein, gamma 1, 45kDa
GLI1 GLI family zinc finger 1
GLS2 glutaminase 2 (liver, mitochondrial)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPR63 G protein-coupled receptor 63
GSTA4 glutathione S-transferase alpha 4
HDAC4 histone deacetylase 4
HEATR4 HEAT repeat containing 4
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HHAT hedgehog acyltransferase
HIC2 hypermethylated in cancer 2
HIRA histone cell cycle regulator
HPS4 Hermansky-Pudlak syndrome 4
HRASLS5 HRAS-like suppressor family, member 5
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IFT74 intraflagellar transport 74
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGF2BP2-AS1 IGF2BP2 antisense RNA 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGSF9 immunoglobulin superfamily, member 9
IL17RA interleukin 17 receptor A
IRS2 insulin receptor substrate 2
ISCA1 iron-sulfur cluster assembly 1
ISM1 isthmin 1, angiogenesis inhibitor
ISPD isoprenoid synthase domain containing
ITPKB inositol-trisphosphate 3-kinase B
JAKMIP2 janus kinase and microtubule interacting protein 2
JOSD1 Josephin domain containing 1
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCTD15 potassium channel tetramerization domain containing 15
KGFLP2 keratinocyte growth factor-like protein 2
KIAA1045 KIAA1045
KIAA1671 KIAA1671
KIF21A kinesin family member 21A
KIF24 kinesin family member 24
KLHL42 kelch-like family member 42
KLRG2 killer cell lectin-like receptor subfamily G, member 2
KREMEN1 kringle containing transmembrane protein 1
KRT17 keratin 17, type I
KRT74 keratin 74, type II
KRT82 keratin 82, type II
LARGE like-glycosyltransferase
LEUTX leucine twenty homeobox
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LIN7C lin-7 homolog C (C. elegans)
LINC00092 long intergenic non-protein coding RNA 92
LINC00161 long intergenic non-protein coding RNA 161
LOC143666 uncharacterized LOC143666
LOH12CR1 loss of heterozygosity, 12, chromosomal region 1
LPAR5 lysophosphatidic acid receptor 5
LPPR5 lipid phosphate phosphatase-related protein type 5
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRIT2 leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
LYPLAL1 lysophospholipase-like 1
M1AP meiosis 1 associated protein
MAGEF1 melanoma antigen family F1
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MARK1 MAP/microtubule affinity-regulating kinase 1
MATN2 matrilin 2
MCM5 minichromosome maintenance complex component 5
MED15 mediator complex subunit 15
MIAT myocardial infarction associated transcript (non-protein coding)
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MIS18A MIS18 kinetochore protein A
MMP11 matrix metallopeptidase 11
MN1 meningioma (disrupted in balanced translocation) 1
MNX1 motor neuron and pancreas homeobox 1
MOB3B MOB kinase activator 3B
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
MPPED1 metallophosphoesterase domain containing 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSI1 musashi RNA-binding protein 1
MTCL1 microtubule crosslinking factor 1
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MYH7 myosin, heavy chain 7, cardiac muscle, beta
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NF2 neurofibromin 2 (merlin)
NFX1 nuclear transcription factor, X-box binding 1
NKD2 naked cuticle homolog 2 (Drosophila)
NKX3-2 NK3 homeobox 2
NPBWR1 neuropeptides B/W receptor 1
NPSR1 neuropeptide S receptor 1
NRXN2 neurexin 2
NRXN3 neurexin 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19
OLMALINC oligodendrocyte maturation-associated long intergenic non-coding RNA
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene)
OR2C1 olfactory receptor, family 2, subfamily C, member 1
OR6C70 olfactory receptor, family 6, subfamily C, member 70
OR7A5 olfactory receptor, family 7, subfamily A, member 5
ORAI3 ORAI calcium release-activated calcium modulator 3
OTOP2 otopetrin 2
OTOP3 otopetrin 3
PANK1 pantothenate kinase 1
PARD6G par-6 family cell polarity regulator gamma
PARL presenilin associated, rhomboid-like
PCDHGB7 protocadherin gamma subfamily B, 7
PCSK2 proprotein convertase subtilisin/kexin type 2
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PES1 pescadillo ribosomal biogenesis factor 1
PEX26 peroxisomal biogenesis factor 26
PEX6 peroxisomal biogenesis factor 6
PGBD5 piggyBac transposable element derived 5
PHF2 PHD finger protein 2
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIANP PILR alpha associated neural protein
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PITPNB phosphatidylinositol transfer protein, beta
PLAA phospholipase A2-activating protein
PLD3 phospholipase D family, member 3
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PNMA6A paraneoplastic Ma antigen family member 6A
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POMC proopiomelanocortin
PPY2P pancreatic polypeptide 2, pseudogene
PRKX protein kinase, X-linked
PRODH proline dehydrogenase (oxidase) 1
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1
PRR14L proline rich 14-like
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTCD1 pentatricopeptide repeat domain 1
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RAB15 RAB15, member RAS oncogene family
RAB6C RAB6C, member RAS oncogene family
RAD51B RAD51 paralog B
RANGAP1 Ran GTPase activating protein 1
RBP7 retinol binding protein 7, cellular
RCOR2 REST corepressor 2
RFC4 replication factor C (activator 1) 4, 37kDa
RFX8 RFX family member 8, lacking RFX DNA binding domain
RHBDD3 rhomboid domain containing 3
RIMBP3 RIMS binding protein 3
RIMS2 regulating synaptic membrane exocytosis 2
RIPPLY3 ripply transcriptional repressor 3
RNF157 ring finger protein 157
RNF38 ring finger protein 38
RPL23P8 ribosomal protein L23 pseudogene 8
RPP25 ribonuclease P/MRP 25kDa subunit
RPP25L ribonuclease P/MRP 25kDa subunit-like
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RRAGD Ras-related GTP binding D
RRM1 ribonucleotide reductase M1
RTN4R reticulon 4 receptor
RUSC2 RUN and SH3 domain containing 2
RYR1 ryanodine receptor 1 (skeletal)
SAMD1 sterile alpha motif domain containing 1
SCAF4 SR-related CTD-associated factor 4
SCAMP5 secretory carrier membrane protein 5
SCARF2 scavenger receptor class F, member 2
SCN5A sodium channel, voltage gated, type V alpha subunit
SELV selenoprotein V
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SEPT5 septin 5
SERTAD3 SERTA domain containing 3
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFT2D3 SFT2 domain containing 3
SIGMAR1 sigma non-opioid intracellular receptor 1
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC10A3 solute carrier family 10, member 3
SLC25A42 solute carrier family 25, member 42
SLC26A5 solute carrier family 26 (anion exchanger), member 5
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SMAD5-AS1 SMAD5 antisense RNA 1
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMO smoothened, frizzled class receptor
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SOX2 SRY (sex determining region Y)-box 2
SOX2-OT SOX2 overlapping transcript
SOX21 SRY (sex determining region Y)-box 21
SOX5 SRY (sex determining region Y)-box 5
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPRTN SprT-like N-terminal domain
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
ST7L suppression of tumorigenicity 7 like
STH saitohin
STMN3 stathmin-like 3
STOX1 storkhead box 1
SUGT1P1 SUGT1 pseudogene 1
TADA2A transcriptional adaptor 2A
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBX1 T-box 1
TBX2 T-box 2
TDH L-threonine dehydrogenase (pseudogene)
TESK1 testis-specific kinase 1
TEX35 testis expressed 35
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFIP11 tuftelin interacting protein 11
THAP8 THAP domain containing 8
TMEM184B transmembrane protein 184B
TMEM194A transmembrane protein 194A
TMEM240 transmembrane protein 240
TMEM246 transmembrane protein 246
TMEM260 transmembrane protein 260
TMEM38B transmembrane protein 38B
TMTC4 transmembrane and tetratricopeptide repeat containing 4
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TPRN taperin
TPST2 tyrosylprotein sulfotransferase 2
TSHZ1 teashirt zinc finger homeobox 1
TSPAN14 tetraspanin 14
TSPAN18 tetraspanin 18
TSPAN33 tetraspanin 33
TTC9B tetratricopeptide repeat domain 9B
TUFT1 tuftelin 1
TULP3 tubby like protein 3
TUSC1 tumor suppressor candidate 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBALD2 UBA-like domain containing 2
UBAP2 ubiquitin associated protein 2
UBE2O ubiquitin-conjugating enzyme E2O
UBE2R2 ubiquitin-conjugating enzyme E2R 2
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4
UNC13B unc-13 homolog B (C. elegans)
USH1G Usher syndrome 1G (autosomal recessive)
VAMP4 vesicle-associated membrane protein 4
VCP valosin containing protein
VGLL4 vestigial-like family member 4
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
VSIG10 V-set and immunoglobulin domain containing 10
WDR11 WD repeat domain 11
WDR34 WD repeat domain 34
WDSUB1 WD repeat, sterile alpha motif and U-box domain containing 1
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
WNT2B wingless-type MMTV integration site family, member 2B
YEATS2 YEATS domain containing 2
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZBTB7C zinc finger and BTB domain containing 7C
ZC2HC1B zinc finger, C2HC-type containing 1B
ZC3H18 zinc finger CCCH-type containing 18
ZDHHC3 zinc finger, DHHC-type containing 3
ZFHX3 zinc finger homeobox 3
ZMYND19 zinc finger, MYND-type containing 19
ZNF546 zinc finger protein 546
ZNF599 zinc finger protein 599
ZNF703 zinc finger protein 703
ZNF777 zinc finger protein 777
ZNF780B zinc finger protein 780B
ZNRF3 zinc and ring finger 3

low expression

Symbol Name
AP3B1 adaptor-related protein complex 3, beta 1 subunit
CUL3 cullin 3