Lung squamous cell carcinoma_LUSC_TCGA-77-7338-01A-11R-2045-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

346 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-77-7338-01A-11R-2045-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AACS acetoacetyl-CoA synthetase
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACACA acetyl-CoA carboxylase alpha
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACKR3 atypical chemokine receptor 3
ACVR1 activin A receptor, type I
ADCY8 adenylate cyclase 8 (brain)
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AFAP1L2 actin filament associated protein 1-like 2
AGFG1 ArfGAP with FG repeats 1
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AHCTF1 AT hook containing transcription factor 1
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
AKAP11 A kinase (PRKA) anchor protein 11
AKT3 v-akt murine thymoma viral oncogene homolog 3
AMTN amelotin
ANKRD13C ankyrin repeat domain 13C
AP1AR adaptor-related protein complex 1 associated regulatory protein
AP3M1 adaptor-related protein complex 3, mu 1 subunit
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARID4B AT rich interactive domain 4B (RBP1-like)
ARL15 ADP-ribosylation factor-like 15
ARSJ arylsulfatase family, member J
ATP10D ATPase, class V, type 10D
ATP13A3 ATPase type 13A3
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATRN attractin
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BBS7 Bardet-Biedl syndrome 7
BCL10 B-cell CLL/lymphoma 10
BNC1 basonuclin 1
BPY2 basic charge, Y-linked, 2
BTBD1 BTB (POZ) domain containing 1
C1ORF106 chromosome 1 open reading frame 106
C1ORF226 chromosome 1 open reading frame 226
C22ORF23 chromosome 22 open reading frame 23
C2CD2 C2 calcium-dependent domain containing 2
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CCSER1 coiled-coil serine-rich protein 1
CCSER2 coiled-coil serine-rich protein 2
CD46 CD46 molecule, complement regulatory protein
CDC73 cell division cycle 73
CDH13 cadherin 13
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CEND1 cell cycle exit and neuronal differentiation 1
CES1P1 carboxylesterase 1 pseudogene 1
CHD9 chromodomain helicase DNA binding protein 9
CHODL-AS1 CHODL antisense RNA 1
CHRM3 cholinergic receptor, muscarinic 3
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLDN14 claudin 14
CLDN8 claudin 8
CNGA1 cyclic nucleotide gated channel alpha 1
COL24A1 collagen, type XXIV, alpha 1
CPEB2 cytoplasmic polyadenylation element binding protein 2
CREB5 cAMP responsive element binding protein 5
CREG2 cellular repressor of E1A-stimulated genes 2
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CTAGE4 CTAGE family, member 4
CTAGE6 CTAGE family, member 6
CTAGE9 CTAGE family, member 9
DCAF6 DDB1 and CUL4 associated factor 6
DCC DCC netrin 1 receptor
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DIEXF digestive organ expansion factor homolog (zebrafish)
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DLG1 discs, large homolog 1 (Drosophila)
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
DPH3P1 diphthamide biosynthesis 3 pseudogene 1
DPP8 dipeptidyl-peptidase 8
DSC3 desmocollin 3
DSG3 desmoglein 3
DSTYK dual serine/threonine and tyrosine protein kinase
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EDIL3 EGF-like repeats and discoidin I-like domains 3
EFNA5 ephrin-A5
EGR2 early growth response 2
EIF5A2 eukaryotic translation initiation factor 5A2
ELOVL6 ELOVL fatty acid elongase 6
EN1 engrailed homeobox 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHB3 EPH receptor B3
EPRS glutamyl-prolyl-tRNA synthetase
ETV3 ets variant 3
EVI5 ecotropic viral integration site 5
EXOC8 exocyst complex component 8
EXOSC9 exosome component 9
F2RL1 coagulation factor II (thrombin) receptor-like 1
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FAM114A1 family with sequence similarity 114, member A1
FAM172A family with sequence similarity 172, member A
FAM25A family with sequence similarity 25, member A
FAM69A family with sequence similarity 69, member A
FAM90A7P putative protein FAM90A7
FAT2 FAT atypical cadherin 2
FBXO45 F-box protein 45
FEM1B fem-1 homolog b (C. elegans)
FERMT1 fermitin family member 1
FGF2 fibroblast growth factor 2 (basic)
FGFBP2 fibroblast growth factor binding protein 2
FKBP1AP1 FK506 binding protein 1A, 12kDa pseudogene 1
FKTN fukutin
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FYTTD1 forty-two-three domain containing 1
GAN gigaxonin
GATSL2 GATS protein-like 2
GCLM glutamate-cysteine ligase, modifier subunit
GFM1 G elongation factor, mitochondrial 1
GJA3 gap junction protein, alpha 3, 46kDa
GJB6 gap junction protein, beta 6, 30kDa
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GNPDA2 glucosamine-6-phosphate deaminase 2
GPR161 G protein-coupled receptor 161
GPR50 G protein-coupled receptor 50
GRK4 G protein-coupled receptor kinase 4
GSTCD glutathione S-transferase, C-terminal domain containing
GSTM2P1 glutathione S-transferase mu 2 (muscle) pseudogene 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HHAT hedgehog acyltransferase
HIAT1 hippocampus abundant transcript 1
HK1 hexokinase 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HSPA12A heat shock 70kDa protein 12A
IDS iduronate 2-sulfatase
IGF1R insulin-like growth factor 1 receptor
IL1RAP interleukin 1 receptor accessory protein
IL22 interleukin 22
IRF2BP2 interferon regulatory factor 2 binding protein 2
IRF6 interferon regulatory factor 6
ITGAV integrin, alpha V
ITGB8 integrin, beta 8
JADE2 jade family PHD finger 2
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNIP4 Kv channel interacting protein 4
KDSR 3-ketodihydrosphingosine reductase
KIAA0226 KIAA0226
KIAA0232 KIAA0232
KIAA0368 KIAA0368
KIAA1109 KIAA1109
KIAA1549L KIAA1549-like
KIAA1804 mixed lineage kinase 4
KIAA2018 KIAA2018
KIF16B kinesin family member 16B
KIF1BP KIF1 binding protein
KLF12 Kruppel-like factor 12
KLHL24 kelch-like family member 24
KPNA6 karyopherin alpha 6 (importin alpha 7)
KRTAP10-1 keratin associated protein 10-1
KRTAP19-7 keratin associated protein 19-7
LACC1 laccase (multicopper oxidoreductase) domain containing 1
LAMA3 laminin, alpha 3
LAMC2 laminin, gamma 2
LARP7 La ribonucleoprotein domain family, member 7
LIN54 lin-54 DREAM MuvB core complex component
LIPN lipase, family member N
LMBR1 limb development membrane protein 1
LOC100129550 uncharacterized LOC100129550
LOC100132111 uncharacterized LOC100132111
LOC340017 uncharacterized LOC340017
LOC401127 WD repeat domain 5 pseudogene
LOC646214 p21 protein (Cdc42/Rac)-activated kinase 2 pseudogene
LOC652276 potassium channel tetramerization domain containing 5 pseudogene
LPCAT2 lysophosphatidylcholine acyltransferase 2
LPP LIM domain containing preferred translocation partner in lipoma
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRIT2 leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
LRP12 low density lipoprotein receptor-related protein 12
LRP1B low density lipoprotein receptor-related protein 1B
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC8C leucine rich repeat containing 8 family, member C
LTN1 listerin E3 ubiquitin protein ligase 1
LYNX1 Ly6/neurotoxin 1
MAB21L3 mab-21-like 3 (C. elegans)
MAP2 microtubule-associated protein 2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MB21D2 Mab-21 domain containing 2
MBOAT2 membrane bound O-acyltransferase domain containing 2
MEF2A myocyte enhancer factor 2A
METTL14 methyltransferase like 14
MFSD1 major facilitator superfamily domain containing 1
MFSD6 major facilitator superfamily domain containing 6
MLANA melan-A
MORC3 MORC family CW-type zinc finger 3
MYO1E myosin IE
MYO5A myosin VA (heavy chain 12, myoxin)
N4BP1 NEDD4 binding protein 1
NAV1 neuron navigator 1
NEFL neurofilament, light polypeptide
NELL2 NEL-like 2 (chicken)
NFASC neurofascin
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1
NIPAL1 NIPA-like domain containing 1
NIPAL2 NIPA-like domain containing 2
NOD2 nucleotide-binding oligomerization domain containing 2
NRBF2 nuclear receptor binding factor 2
NRIP1 nuclear receptor interacting protein 1
NSUN3 NOP2/Sun domain family, member 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OLFM1 olfactomedin 1
OPA1 optic atrophy 1 (autosomal dominant)
OSMR oncostatin M receptor
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PARD6G par-6 family cell polarity regulator gamma
PCDHGA7 protocadherin gamma subfamily A, 7
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDLIM5 PDZ and LIM domain 5
PDS5A PDS5 cohesin associated factor A
PGLYRP3 peptidoglycan recognition protein 3
PIGX phosphatidylinositol glycan anchor biosynthesis, class X
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKLR pyruvate kinase, liver and RBC
PLA2G3 phospholipase A2, group III
PLXNA2 plexin A2
PNPLA1 patatin-like phospholipase domain containing 1
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRKCA protein kinase C, alpha
PRKCI protein kinase C, iota
PRSS3P2 protease, serine, 3 pseudogene 2
PTCHD3 patched domain containing 3
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTPN3 protein tyrosine phosphatase, non-receptor type 3
RAD21L1 RAD21-like 1 (S. pombe)
RAP2B RAP2B, member of RAS oncogene family
RBM11 RNA binding motif protein 11
REEP3 receptor accessory protein 3
RNASE10 ribonuclease, RNase A family, 10 (non-active)
RNF103 ring finger protein 103
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF2 ring finger protein 2
RNF4 ring finger protein 4
RPTN repetin
RUFY2 RUN and FYVE domain containing 2
RUNX1 runt-related transcription factor 1
RXFP1 relaxin/insulin-like family peptide receptor 1
SAMD8 sterile alpha motif domain containing 8
SCAMP1 secretory carrier membrane protein 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC24B SEC24 family member B
SEC24D SEC24 family member D
SENP5 SUMO1/sentrin specific peptidase 5
SERP2 stress-associated endoplasmic reticulum protein family member 2
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SETX senataxin
SGPL1 sphingosine-1-phosphate lyase 1
SKIL SKI-like proto-oncogene
SLAIN2 SLAIN motif family, member 2
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6
SLC26A10 solute carrier family 26, member 10
SLC30A7 solute carrier family 30 (zinc transporter), member 7
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC35F3 solute carrier family 35, member F3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC7A4 solute carrier family 7, member 4
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
SLMAP sarcolemma associated protein
SMN1 survival of motor neuron 1, telomeric
SNORA40 small nucleolar RNA, H/ACA box 40
SNORA62 small nucleolar RNA, H/ACA box 62
SNORA65 small nucleolar RNA, H/ACA box 65
SPATA1 spermatogenesis associated 1
SPATA5 spermatogenesis associated 5
SPPL2A signal peptide peptidase like 2A
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
ST7-AS2 ST7 antisense RNA 2
STK32B serine/threonine kinase 32B
STXBP5 syntaxin binding protein 5 (tomosyn)
SYNDIG1 synapse differentiation inducing 1
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TARBP1 TAR (HIV-1) RNA binding protein 1
TBC1D14 TBC1 domain family, member 14
TBCK TBC1 domain containing kinase
TBX20 T-box 20
TENM2 teneurin transmembrane protein 2
TET2 tet methylcytosine dioxygenase 2
TEX35 testis expressed 35
TGFBI transforming growth factor, beta-induced, 68kDa
THBD thrombomodulin
THSD4 thrombospondin, type I, domain containing 4
TLK1 tousled-like kinase 1
TLR6 toll-like receptor 6
TM9SF3 transmembrane 9 superfamily member 3
TMX3 thioredoxin-related transmembrane protein 3
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNNI1 troponin I type 1 (skeletal, slow)
TP53INP2 tumor protein p53 inducible nuclear protein 2
TRAM1L1 translocation associated membrane protein 1-like 1
TREML3P triggering receptor expressed on myeloid cells-like 3, pseudogene
TROVE2 TROVE domain family, member 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2K ubiquitin-conjugating enzyme E2K
UBE3C ubiquitin protein ligase E3C
UBQLN1 ubiquilin 1
UBQLN2 ubiquilin 2
UBXN7 UBX domain protein 7
UHMK1 U2AF homology motif (UHM) kinase 1
UNC5B unc-5 homolog B (C. elegans)
UPK1B uroplakin 1B
USP53 ubiquitin specific peptidase 53
VDAC2 voltage-dependent anion channel 2
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
VWA8 von Willebrand factor A domain containing 8
WNT5A wingless-type MMTV integration site family, member 5A
WSB2 WD repeat and SOCS box containing 2
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YOD1 YOD1 deubiquitinase
ZBTB41 zinc finger and BTB domain containing 41
ZC3H12C zinc finger CCCH-type containing 12C
ZC3H13 zinc finger CCCH-type containing 13
ZCCHC6 zinc finger, CCHC domain containing 6
ZFAT-AS1 ZFAT antisense RNA 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZMAT3 zinc finger, matrin-type 3
ZNF365 zinc finger protein 365
ZNF518B zinc finger protein 518B
ZNF770 zinc finger protein 770
ZZZ3 zinc finger, ZZ-type containing 3