Lung squamous cell carcinoma_LUSC_TCGA-66-2792-01A-01R-0980-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

417 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-66-2792-01A-01R-0980-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ABHD15 abhydrolase domain containing 15
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTL6A actin-like 6A
ACVR1 activin A receptor, type I
ADGRG7 adhesion G protein-coupled receptor G7
ADORA2B adenosine A2b receptor
AK3 adenylate kinase 3
ALG3 ALG3, alpha-1,3- mannosyltransferase
ALKBH5 AlkB family member 5, RNA demethylase
AMMECR1L AMMECR1-like
AOAH acyloxyacyl hydrolase (neutrophil)
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ARL13B ADP-ribosylation factor-like 13B
ARL4D ADP-ribosylation factor-like 4D
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ATRNL1 attractin-like 1
ATXN7L1 ataxin 7-like 1
AURKB aurora kinase B
BCAS3 breast carcinoma amplified sequence 3
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTBD7 BTB (POZ) domain containing 7
C17ORF53 chromosome 17 open reading frame 53
C17ORF96 chromosome 17 open reading frame 96
C19ORF54 chromosome 19 open reading frame 54
C20ORF194 chromosome 20 open reading frame 194
C9ORF40 chromosome 9 open reading frame 40
C9ORF41 chromosome 9 open reading frame 41
C9ORF64 chromosome 9 open reading frame 64
C9ORF91 chromosome 9 open reading frame 91
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CBX1 chromobox homolog 1
CCDC115 coiled-coil domain containing 115
CCDC126 coiled-coil domain containing 126
CCDC3 coiled-coil domain containing 3
CCNB2 cyclin B2
CCND2 cyclin D2
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CDC14C cell division cycle 14C
CDC26 cell division cycle 26
CDC6 cell division cycle 6
CDH8 cadherin 8, type 2
CECR2 cat eye syndrome chromosome region, candidate 2
CECR5 cat eye syndrome chromosome region, candidate 5
CENPO centromere protein O
CENPP centromere protein P
CEP78 centrosomal protein 78kDa
CEP97 centrosomal protein 97kDa
CERS6 ceramide synthase 6
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2
CHRM3 cholinergic receptor, muscarinic 3
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
CKMT1A creatine kinase, mitochondrial 1A
CKMT1B creatine kinase, mitochondrial 1B
CLCN2 chloride channel, voltage-sensitive 2
CMSS1 cms1 ribosomal small subunit homolog (yeast)
CNTNAP2 contactin associated protein-like 2
COG5 component of oligomeric golgi complex 5
COPS3 COP9 signalosome subunit 3
COPZ2 coatomer protein complex, subunit zeta 2
CORO2A coronin, actin binding protein, 2A
CPA6 carboxypeptidase A6
CPOX coproporphyrinogen oxidase
CRMP1 collapsin response mediator protein 1
CSRP2 cysteine and glycine-rich protein 2
CTDNEP1 CTD nuclear envelope phosphatase 1
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CUX1 cut-like homeobox 1
CYB5D2 cytochrome b5 domain containing 2
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
DACT2 dishevelled-binding antagonist of beta-catenin 2
DCAF12L2 DDB1 and CUL4 associated factor 12-like 2
DCAF17 DDB1 and CUL4 associated factor 17
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1
DDIAS DNA damage-induced apoptosis suppressor
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40
DKKL1 dickkopf-like 1
DLD dihydrolipoamide dehydrogenase
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOLPP1 dolichyldiphosphatase 1
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
DUSP14 dual specificity phosphatase 14
DVL2 dishevelled segment polarity protein 2
DVL3 dishevelled segment polarity protein 3
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
ECE2 endothelin converting enzyme 2
EGFR epidermal growth factor receptor
EHF ets homologous factor
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EIF1 eukaryotic translation initiation factor 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ELP5 elongator acetyltransferase complex subunit 5
EMILIN3 elastin microfibril interfacer 3
ERCC3 excision repair cross-complementation group 3
ERCC6L excision repair cross-complementation group 6-like
ERCC6L2 excision repair cross-complementation group 6-like 2
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1
FAM120AOS family with sequence similarity 120A opposite strand
FAM131A family with sequence similarity 131, member A
FAM134C family with sequence similarity 134, member C
FAM200A family with sequence similarity 200, member A
FAM221A family with sequence similarity 221, member A
FAN1 FANCD2/FANCI-associated nuclease 1
FANCC Fanconi anemia, complementation group C
FANCM Fanconi anemia, complementation group M
FAXC failed axon connections homolog (Drosophila)
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGF11 fibroblast growth factor 11
FN3KRP fructosamine 3 kinase related protein
FNTB farnesyltransferase, CAAX box, beta
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FRRS1L ferric-chelate reductase 1-like
FST follistatin
FSTL4 follistatin-like 4
FSTL5 follistatin-like 5
FXR1 fragile X mental retardation, autosomal homolog 1
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GBAS glioblastoma amplified sequence
GDA guanine deaminase
GEMIN4 gem (nuclear organelle) associated protein 4
GID4 GID complex subunit 4
GINS1 GINS complex subunit 1 (Psf1 homolog)
GLOD4 glyoxalase domain containing 4
GOLGA1 golgin A1
GPATCH11 G patch domain containing 11
GPC3 glypican 3
GPC4 glypican 4
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR1 G protein-coupled receptor 1
GREB1L growth regulation by estrogen in breast cancer-like
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRK7 G protein-coupled receptor kinase 7
GSG2 germ cell associated 2 (haspin)
GSTCD glutathione S-transferase, C-terminal domain containing
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GTSE1 G-2 and S-phase expressed 1
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
HAUS2 HAUS augmin-like complex, subunit 2
HAUS4 HAUS augmin-like complex, subunit 4
HAUS6 HAUS augmin-like complex, subunit 6
HCRTR1 hypocretin (orexin) receptor 1
HEATR4 HEAT repeat containing 4
HIATL1 hippocampus abundant transcript-like 1
HIPK3 homeodomain interacting protein kinase 3
HLF hepatic leukemia factor
HYAL3 hyaluronoglucosaminidase 3
IARS isoleucyl-tRNA synthetase
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IMP4 IMP4, U3 small nucleolar ribonucleoprotein
IMPACT impact RWD domain protein
INVS inversin
ISCA1 iron-sulfur cluster assembly 1
ISCA1P1 iron-sulfur cluster assembly 1 pseudogene 1
KATNBL1 katanin p80 subunit B-like 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM3A lysine (K)-specific demethylase 3A
KIAA1045 KIAA1045
KIAA1524 KIAA1524
KIAA1715 KIAA1715
KIAA2022 KIAA2022
KLHL11 kelch-like family member 11
KLHL13 kelch-like family member 13
KNSTRN kinetochore-localized astrin/SPAG5 binding protein
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRT19 keratin 19, type I
KRTAP4-1 keratin associated protein 4-1
KRTAP5-6 keratin associated protein 5-6
L2HGDH L-2-hydroxyglutarate dehydrogenase
LARGE like-glycosyltransferase
LCLAT1 lysocardiolipin acyltransferase 1
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LIG3 ligase III, DNA, ATP-dependent
LIMS1 LIM and senescent cell antigen-like domains 1
LOC100130691 uncharacterized LOC100130691
LOC100133985 uncharacterized LOC100133985
LOC154761 family with sequence similarity 115, member C pseudogene
LOC728554 THO complex 3 pseudogene
LPPR1 lipid phosphate phosphatase-related protein type 1
LRP4 low density lipoprotein receptor-related protein 4
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
LRRC4 leucine rich repeat containing 4
LRRC57 leucine rich repeat containing 57
LRRC8D leucine rich repeat containing 8 family, member D
LRRC8E leucine rich repeat containing 8 family, member E
LTBP1 latent transforming growth factor beta binding protein 1
LYPD6 LY6/PLAUR domain containing 6
LYPD6B LY6/PLAUR domain containing 6B
M1AP meiosis 1 associated protein
MAB21L1 mab-21-like 1 (C. elegans)
MAGEB6 melanoma antigen family B6
MAGEF1 melanoma antigen family F1
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPK6 mitogen-activated protein kinase 6
MBLAC1 metallo-beta-lactamase domain containing 1
MCM7 minichromosome maintenance complex component 7
MCM8 minichromosome maintenance complex component 8
MEGF10 multiple EGF-like-domains 10
MEPCE methylphosphate capping enzyme
MERTK MER proto-oncogene, tyrosine kinase
METTL2B methyltransferase like 2B
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MFN1 mitofusin 1
MFSD11 major facilitator superfamily domain containing 11
MIS12 MIS12 kinetochore complex component
MLH3 mutL homolog 3
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MNAT1 MNAT CDK-activating kinase assembly factor 1
MYO19 myosin XIX
MYO5A myosin VA (heavy chain 12, myoxin)
MZT2B mitotic spindle organizing protein 2B
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2
NAGA N-acetylgalactosaminidase, alpha-
NANP N-acetylneuraminic acid phosphatase
NBPF3 neuroblastoma breakpoint family, member 3
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NDNL2 necdin-like 2
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFE2L2 nuclear factor, erythroid 2-like 2
NKAIN1 Na+/K+ transporting ATPase interacting 1
NPBWR1 neuropeptides B/W receptor 1
NRG1 neuregulin 1
NRN1 neuritin 1
NRXN3 neurexin 3
NT5M 5',3'-nucleotidase, mitochondrial
NTN1 netrin 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUP88 nucleoporin 88kDa
OPRK1 opioid receptor, kappa 1
OR1J1 olfactory receptor, family 1, subfamily J, member 1
OR9A4 olfactory receptor, family 9, subfamily A, member 4
ORC5 origin recognition complex, subunit 5
OSTF1 osteoclast stimulating factor 1
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PALM2 paralemmin 2
PANK3 pantothenate kinase 3
PARD3 par-3 family cell polarity regulator
PARL presenilin associated, rhomboid-like
PCDH19 protocadherin 19
PCDHGB1 protocadherin gamma subfamily B, 1
PCGF2 polycomb group ring finger 2
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
PCSK5 proprotein convertase subtilisin/kexin type 5
PDE9A phosphodiesterase 9A
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PELI1 pellino E3 ubiquitin protein ligase 1
PELI2 pellino E3 ubiquitin protein ligase family member 2
PENK proenkephalin
PEX12 peroxisomal biogenesis factor 12
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGK1 phosphoglycerate kinase 1
PHF19 PHD finger protein 19
PHF3 PHD finger protein 3
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PIGW phosphatidylinositol glycan anchor biosynthesis, class W
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2R1 phospholipase A2 receptor 1, 180kDa
PLD6 phospholipase D family, member 6
PNPLA8 patatin-like phospholipase domain containing 8
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
POMZP3 POM121 and ZP3 fusion
PRDM11 PR domain containing 11
PRIMA1 proline rich membrane anchor 1
PROSER2 proline and serine rich 2
PRPF4 pre-mRNA processing factor 4
PSAT1 phosphoserine aminotransferase 1
PSEN1 presenilin 1
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSPH phosphoserine phosphatase
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PUS7 pseudouridylate synthase 7 (putative)
PYGO1 pygopus family PHD finger 1
RAB5C RAB5C, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAD51 RAD51 recombinase
RAD51D RAD51 paralog D
RALB v-ral simian leukemia viral oncogene homolog B
RB1CC1 RB1-inducible coiled-coil 1
RBBP8 retinoblastoma binding protein 8
RC3H2 ring finger and CCCH-type domains 2
RCOR2 REST corepressor 2
REV1 REV1, polymerase (DNA directed)
RFC5 replication factor C (activator 1) 5, 36.5kDa
RFX7 regulatory factor X, 7
RGMB repulsive guidance molecule family member b
RIMBP3 RIMS binding protein 3
RINT1 RAD50 interactor 1
RMI1 RecQ mediated genome instability 1
RNF167 ring finger protein 167
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
RRM2 ribonucleotide reductase M2
SAP130 Sin3A-associated protein, 130kDa
SAV1 salvador family WW domain containing protein 1
SDK2 sidekick cell adhesion molecule 2
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SESN3 sestrin 3
SFT2D3 SFT2 domain containing 3
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIX4 SIX homeobox 4
SLAMF9 SLAM family member 9
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC16A13 solute carrier family 16, member 13
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC25A35 solute carrier family 25, member 35
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC4A11 solute carrier family 4, sodium borate transporter, member 11
SMC2 structural maintenance of chromosomes 2
SMG6 SMG6 nonsense mediated mRNA decay factor
SMO smoothened, frizzled class receptor
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
SMYD3 SET and MYND domain containing 3
SPANXN3 SPANX family, member N3
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPIN1 spindlin 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRFBP1 serum response factor binding protein 1
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SRPK2 SRSF protein kinase 2
SRY sex determining region Y
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
STK39 serine threonine kinase 39
STRN striatin, calmodulin binding protein
STRN3 striatin, calmodulin binding protein 3
STXBP6 syntaxin binding protein 6 (amisyn)
SUMF2 sulfatase modifying factor 2
TADA2A transcriptional adaptor 2A
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D23 TBC1 domain family, member 23
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBX15 T-box 15
TGM4 transglutaminase 4
THAP5 THAP domain containing 5
THOC3 THO complex 3
THSD7B thrombospondin, type I, domain containing 7B
THTPA thiamine triphosphatase
TLX3 T-cell leukemia homeobox 3
TMEM145 transmembrane protein 145
TMEM185B transmembrane protein 185B
TMEM200B transmembrane protein 200B
TMEM209 transmembrane protein 209
TMEM246 transmembrane protein 246
TMEM260 transmembrane protein 260
TMPRSS13 transmembrane protease, serine 13
TMPRSS4 transmembrane protease, serine 4
TMSB4Y thymosin beta 4, Y-linked
TMX1 thioredoxin-related transmembrane protein 1
TOM1L1 target of myb1 (chicken)-like 1
TRIM2 tripartite motif containing 2
TRIM32 tripartite motif containing 32
TSPAN18 tetraspanin 18
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
TTC21B tetratricopeptide repeat domain 21B
TTC28 tetratricopeptide repeat domain 28
TTC39B tetratricopeptide repeat domain 39B
TUBGCP4 tubulin, gamma complex associated protein 4
TYRO3 TYRO3 protein tyrosine kinase
UBE3A ubiquitin protein ligase E3A
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
VLDLR very low density lipoprotein receptor
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
WBSCR27 Williams Beuren syndrome chromosome region 27
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR45B WD repeat domain 45B
WDR54 WD repeat domain 54
WWC2-AS2 WWC2 antisense RNA 2
YEATS2 YEATS domain containing 2
ZBTB25 zinc finger and BTB domain containing 25
ZBTB34 zinc finger and BTB domain containing 34
ZBTB6 zinc finger and BTB domain containing 6
ZFP3 ZFP3 zinc finger protein
ZFP37 ZFP37 zinc finger protein
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZMAT3 zinc finger, matrin-type 3
ZNF181 zinc finger protein 181
ZNF189 zinc finger protein 189
ZNF280B zinc finger protein 280B
ZNF287 zinc finger protein 287
ZNF30 zinc finger protein 30
ZNF462 zinc finger protein 462
ZNF510 zinc finger protein 510
ZNF624 zinc finger protein 624
ZNF639 zinc finger protein 639
ZNF714 zinc finger protein 714
ZNF829 zinc finger protein 829
ZSCAN21 zinc finger and SCAN domain containing 21
ZSCAN29 zinc finger and SCAN domain containing 29

low expression

Symbol Name
ARAF A-Raf proto-oncogene, serine/threonine kinase
ZNF562 zinc finger protein 562