Lung squamous cell carcinoma_LUSC_TCGA-66-2783-01A-01R-1201-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

415 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-66-2783-01A-01R-1201-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACAD9 acyl-CoA dehydrogenase family, member 9
ACOT13 acyl-CoA thioesterase 13
ADAM15 ADAM metallopeptidase domain 15
ADGRV1 adhesion G protein-coupled receptor V1
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADIPOR1 adiponectin receptor 1
ADM adrenomedullin
AFP alpha-fetoprotein
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AHCYL1 adenosylhomocysteinase-like 1
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C2 aldo-keto reductase family 1, member C2
AKR1E2 aldo-keto reductase family 1, member E2
ALDH9A1 aldehyde dehydrogenase 9 family, member A1
ALDOA aldolase A, fructose-bisphosphate
AMZ2 archaelysin family metallopeptidase 2
ANAPC13 anaphase promoting complex subunit 13
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKRD37 ankyrin repeat domain 37
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOL1 apolipoprotein L, 1
APOL2 apolipoprotein L, 2
ARMC7 armadillo repeat containing 7
ARPC5L actin related protein 2/3 complex, subunit 5-like
ATL3 atlastin GTPase 3
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATXN1 ataxin 1
AXDND1 axonemal dynein light chain domain containing 1
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BCO1 beta-carotene oxygenase 1
BIK BCL2-interacting killer (apoptosis-inducing)
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted
BPIFA1 BPI fold containing family A, member 1
C10ORF99 chromosome 10 open reading frame 99
C1ORF177 chromosome 1 open reading frame 177
C1ORF21 chromosome 1 open reading frame 21
C3ORF58 chromosome 3 open reading frame 58
C4ORF3 chromosome 4 open reading frame 3
C5ORF52 chromosome 5 open reading frame 52
C6ORF52 chromosome 6 open reading frame 52
C9ORF172 chromosome 9 open reading frame 172
C9ORF69 chromosome 9 open reading frame 69
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CARD17 caspase recruitment domain family, member 17
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CASKIN2 CASK interacting protein 2
CBR1 carbonyl reductase 1
CBR3 carbonyl reductase 3
CBX6 chromobox homolog 6
CDC27 cell division cycle 27
CDH24 cadherin 24, type 2
CDIP1 cell death-inducing p53 target 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CDYL chromodomain protein, Y-like
CENPB centromere protein B, 80kDa
CEP97 centrosomal protein 97kDa
CES1 carboxylesterase 1
CH25H cholesterol 25-hydroxylase
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHMP1B charged multivesicular body protein 1B
CHODL chondrolectin
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CISD2 CDGSH iron sulfur domain 2
CLDN8 claudin 8
CLDND1 claudin domain containing 1
CLINT1 clathrin interactor 1
CNOT4 CCR4-NOT transcription complex, subunit 4
COBLL1 cordon-bleu WH2 repeat protein-like 1
COPZ2 coatomer protein complex, subunit zeta 2
CORO2A coronin, actin binding protein, 2A
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPOX coproporphyrinogen oxidase
CREG1 cellular repressor of E1A-stimulated genes 1
CRYGS crystallin, gamma S
CSNK1A1 casein kinase 1, alpha 1
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A3 casein kinase 2, alpha 3 polypeptide
CSTA cystatin A (stefin A)
DAB2IP DAB2 interacting protein
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBP D site of albumin promoter (albumin D-box) binding protein
DDRGK1 DDRGK domain containing 1
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DEAF1 DEAF1 transcription factor
DEFB126 defensin, beta 126
DEK DEK proto-oncogene
DESI1 desumoylating isopeptidase 1
DHFR dihydrofolate reductase
DHRS3 dehydrogenase/reductase (SDR family) member 3
DIRC2 disrupted in renal carcinoma 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAL4 dynein, axonemal, light chain 4
DSCR3 Down syndrome critical region 3
DTWD2 DTW domain containing 2
DTX3L deltex 3 like, E3 ubiquitin ligase
EGLN1 egl-9 family hypoxia-inducible factor 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELL2 elongation factor, RNA polymerase II, 2
ENO2 enolase 2 (gamma, neuronal)
EPHB1 EPH receptor B1
EPHB3 EPH receptor B3
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ETF1 eukaryotic translation termination factor 1
F12 coagulation factor XII (Hageman factor)
FADS2 fatty acid desaturase 2
FAF2 Fas associated factor family member 2
FAM102A family with sequence similarity 102, member A
FAM110C family with sequence similarity 110, member C
FAM111B family with sequence similarity 111, member B
FAM120A family with sequence similarity 120A
FAM129B family with sequence similarity 129, member B
FAM162A family with sequence similarity 162, member A
FAM170B family with sequence similarity 170, member B
FAM172A family with sequence similarity 172, member A
FAM207A family with sequence similarity 207, member A
FAM20B family with sequence similarity 20, member B
FAM50B family with sequence similarity 50, member B
FAM66D family with sequence similarity 66, member D
FAM83F family with sequence similarity 83, member F
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial
FBLIM1 filamin binding LIM protein 1
FBXW11 F-box and WD repeat domain containing 11
FBXW5 F-box and WD repeat domain containing 5
FDPS farnesyl diphosphate synthase
FEM1C fem-1 homolog c (C. elegans)
FOXK2 forkhead box K2
FRRS1 ferric-chelate reductase 1
FTH1 ferritin, heavy polypeptide 1
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
GAB1 GRB2-associated binding protein 1
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GAMT guanidinoacetate N-methyltransferase
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GBP6 guanylate binding protein family, member 6
GCLM glutamate-cysteine ligase, modifier subunit
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GFOD1 glucose-fructose oxidoreductase domain containing 1
GMPS guanine monphosphate synthase
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GOSR2 golgi SNAP receptor complex member 2
GPRIN1 G protein regulated inducer of neurite outgrowth 1
GPX2 glutathione peroxidase 2
GRK6 G protein-coupled receptor kinase 6
GSK3B glycogen synthase kinase 3 beta
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
GUSB glucuronidase, beta
H1FX H1 histone family, member X
HACD2 3-hydroxyacyl-CoA dehydratase 2
HADH hydroxyacyl-CoA dehydrogenase
HAX1 HCLS1 associated protein X-1
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HES5 hes family bHLH transcription factor 5
HIAT1 hippocampus abundant transcript 1
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIST1H2AC histone cluster 1, H2ac
HIST1H2AD histone cluster 1, H2ad
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BK histone cluster 1, H2bk
HIST1H4H histone cluster 1, H4h
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HUS1B HUS1 checkpoint homolog b (S. pombe)
IL20RB interleukin 20 receptor beta
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
IPMK inositol polyphosphate multikinase
IPO11 importin 11
IQCB1 IQ motif containing B1
ITPK1 inositol-tetrakisphosphate 1-kinase
JARID2 jumonji, AT rich interactive domain 2
JMY junction mediating and regulatory protein, p53 cofactor
KIAA1191 KIAA1191
KIF13A kinesin family member 13A
KPNA1 karyopherin alpha 1 (importin alpha 5)
KPNA4 karyopherin alpha 4 (importin alpha 3)
KPRP keratinocyte proline-rich protein
LALBA lactalbumin, alpha-
LARP1 La ribonucleoprotein domain family, member 1
LCN2 lipocalin 2
LINC00161 long intergenic non-protein coding RNA 161
LOC100133050 glucuronidase, beta pseudogene
LOC154761 family with sequence similarity 115, member C pseudogene
LOC284837
LOC285629 uncharacterized LOC285629
LOC388955 PRELI domain-containing protein 1, mitochondrial pseudogene
LPP LIM domain containing preferred translocation partner in lipoma
LRRC46 leucine rich repeat containing 46
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LYZL1 lysozyme-like 1
MAB21L3 mab-21-like 3 (C. elegans)
MAPKAP1 mitogen-activated protein kinase associated protein 1
MBD2 methyl-CpG binding domain protein 2
MBD4 methyl-CpG binding domain protein 4
MCM2 minichromosome maintenance complex component 2
MCUR1 mitochondrial calcium uniporter regulator 1
MED27 mediator complex subunit 27
MEGF9 multiple EGF-like-domains 9
METTL2A methyltransferase like 2A
METTL4 methyltransferase like 4
MFAP3 microfibrillar-associated protein 3
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MGST1 microsomal glutathione S-transferase 1
MORC2 MORC family CW-type zinc finger 2
MRPL22 mitochondrial ribosomal protein L22
MRPL27 mitochondrial ribosomal protein L27
MRPL37 mitochondrial ribosomal protein L37
MSH3 mutS homolog 3
MSL2 male-specific lethal 2 homolog (Drosophila)
MSMO1 methylsterol monooxygenase 1
MTMR2 myotubularin related protein 2
MZT2A mitotic spindle organizing protein 2A
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NAMPT nicotinamide phosphoribosyltransferase
NARF nuclear prelamin A recognition factor
NCAPH2 non-SMC condensin II complex, subunit H2
NCS1 neuronal calcium sensor 1
NDRG1 N-myc downstream regulated 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1
NHP2 NHP2 ribonucleoprotein
NMB neuromedin B
NMUR2 neuromedin U receptor 2
NOL11 nucleolar protein 11
NPDC1 neural proliferation, differentiation and control, 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NQO2 NAD(P)H dehydrogenase, quinone 2
NR1D1 nuclear receptor subfamily 1, group D, member 1
NRSN2 neurensin 2
NSG1 neuron specific gene family member 1
NT5C 5', 3'-nucleotidase, cytosolic
NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1
NUP153 nucleoporin 153kDa
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3
ONECUT1 one cut homeobox 1
OR10A3 olfactory receptor, family 10, subfamily A, member 3
OSGIN1 oxidative stress induced growth inhibitor 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PANK3 pantothenate kinase 3
PANX2 pannexin 2
PARD3 par-3 family cell polarity regulator
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PAWR PRKC, apoptosis, WT1, regulator
PC pyruvate carboxylase
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PDLIM5 PDZ and LIM domain 5
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase
PFKL phosphofructokinase, liver
PFN2 profilin 2
PGD phosphogluconate dehydrogenase
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIGP phosphatidylinositol glycan anchor biosynthesis, class P
PITX1 paired-like homeodomain 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLS1 plastin 1
PMF1 polyamine-modulated factor 1
PNPO pyridoxamine 5'-phosphate oxidase
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3
PPAP2C phosphatidic acid phosphatase type 2C
PPP1R3G protein phosphatase 1, regulatory subunit 3G
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PPP6C protein phosphatase 6, catalytic subunit
PRCC papillary renal cell carcinoma (translocation-associated)
PRDX1 peroxiredoxin 1
PRDX6 peroxiredoxin 6
PRELID2 PRELI domain containing 2
PROM2 prominin 2
PRPF4 pre-mRNA processing factor 4
PRR7 proline rich 7 (synaptic)
PSAT1 phosphoserine aminotransferase 1
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PTGR1 prostaglandin reductase 1
PTTG1 pituitary tumor-transforming 1
PWWP2A PWWP domain containing 2A
RAB12 RAB12, member RAS oncogene family
RAB14 RAB14, member RAS oncogene family
RABIF RAB interacting factor
RABL6 RAB, member RAS oncogene family-like 6
RAD23A RAD23 homolog A (S. cerevisiae)
RANBP9 RAN binding protein 9
RARS arginyl-tRNA synthetase
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RECQL5 RecQ protein-like 5
RHOC ras homolog family member C
RIBC2 RIB43A domain with coiled-coils 2
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RNF145 ring finger protein 145
RNF187 ring finger protein 187
RNF24 ring finger protein 24
RNF39 ring finger protein 39
RNF44 ring finger protein 44
ROM1 retinal outer segment membrane protein 1
RORA RAR-related orphan receptor A
RXRA retinoid X receptor, alpha
SAP30BP SAP30 binding protein
SCN4A sodium channel, voltage gated, type IV alpha subunit
SFN stratifin
SFXN1 sideroflexin 1
SH3PXD2B SH3 and PX domains 2B
SH3RF2 SH3 domain containing ring finger 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIAH2 siah E3 ubiquitin protein ligase 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC39A3 solute carrier family 39 (zinc transporter), member 3
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLN sarcolipin
SLU7 SLU7 splicing factor homolog (S. cerevisiae)
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMG7 SMG7 nonsense mediated mRNA decay factor
SOD1 superoxide dismutase 1, soluble
SQSTM1 sequestosome 1
SREBF2 sterol regulatory element binding transcription factor 2
SRXN1 sulfiredoxin 1
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STIM1 stromal interaction molecule 1
STRBP spermatid perinuclear RNA binding protein
SUMO3 small ubiquitin-like modifier 3
TALDO1 transaldolase 1
TARM1 T cell-interacting, activating receptor on myeloid cells 1
TBC1D2 TBC1 domain family, member 2
TBC1D7 TBC1 domain family, member 7
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TCAF2 TRPM8 channel-associated factor 2
TCHH trichohyalin
TDP2 tyrosyl-DNA phosphodiesterase 2
TEF thyrotrophic embryonic factor
TEX2 testis expressed 2
TEX26 testis expressed 26
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TFG TRK-fused gene
TGM5 transglutaminase 5
TIGD7 tigger transposable element derived 7
TM4SF1 transmembrane 4 L six family member 1
TMEM109 transmembrane protein 109
TMEM179 transmembrane protein 179
TMEM54 transmembrane protein 54
TPMT thiopurine S-methyltransferase
TRIB3 tribbles pseudokinase 3
TRIM2 tripartite motif containing 2
TRIM32 tripartite motif containing 32
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae)
TSEN15 TSEN15 tRNA splicing endonuclease subunit
TSPO translocator protein (18kDa)
TTC1 tetratricopeptide repeat domain 1
TTC22 tetratricopeptide repeat domain 22
TTLL12 tubulin tyrosine ligase-like family member 12
TTLL5 tubulin tyrosine ligase-like family member 5
TTTY15 testis-specific transcript, Y-linked 15 (non-protein coding)
TXNL4A thioredoxin-like 4A
TYMSOS TYMS opposite strand
U2AF1 U2 small nuclear RNA auxiliary factor 1
UBALD2 UBA-like domain containing 2
UBTD2 ubiquitin domain containing 2
UBXN6 UBX domain protein 6
UCK1 uridine-cytidine kinase 1
UGCG UDP-glucose ceramide glucosyltransferase
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
UMPS uridine monophosphate synthetase
UNC119B unc-119 homolog B (C. elegans)
URM1 ubiquitin related modifier 1
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
VDAC2 voltage-dependent anion channel 2
WBP2 WW domain binding protein 2
WDR18 WD repeat domain 18
WDR24 WD repeat domain 24
WDR41 WD repeat domain 41
WDR72 WD repeat domain 72
WDR76 WD repeat domain 76
WNT7B wingless-type MMTV integration site family, member 7B
WRB tryptophan rich basic protein
WSB2 WD repeat and SOCS box containing 2
XYLT2 xylosyltransferase II
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YY1AP1 YY1 associated protein 1
ZBED8 zinc finger, BED-type containing 8
ZBTB11 zinc finger and BTB domain containing 11
ZBTB7B zinc finger and BTB domain containing 7B
ZBTB7C zinc finger and BTB domain containing 7C
ZDHHC12 zinc finger, DHHC-type containing 12
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF132 zinc finger protein 132
ZNF148 zinc finger protein 148
ZNF219 zinc finger protein 219
ZNF436 zinc finger protein 436
ZNF658 zinc finger protein 658
ZSCAN31 zinc finger and SCAN domain containing 31

low expression

Symbol Name
DAGLB diacylglycerol lipase, beta
RNF216P1 ring finger protein 216 pseudogene 1
ZBTB2 zinc finger and BTB domain containing 2