Lung squamous cell carcinoma_LUSC_TCGA-66-2782-01A-01R-0851-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

383 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-66-2782-01A-01R-0851-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ACP6 acid phosphatase 6, lysophosphatidic
ACY1 aminoacylase 1
ADCK5 aarF domain containing kinase 5
ADGRG3 adhesion G protein-coupled receptor G3
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADORA2B adenosine A2b receptor
AGBL3 ATP/GTP binding protein-like 3
AGK acylglycerol kinase
AGTRAP angiotensin II receptor-associated protein
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
ALG10 ALG10, alpha-1,2-glucosyltransferase
ANXA8 annexin A8
ANXA8L1 annexin A8-like 1
ARHGAP4 Rho GTPase activating protein 4
ARL9 ADP-ribosylation factor-like 9
ASB13 ankyrin repeat and SOCS box containing 13
ASIC5 acid sensing (proton gated) ion channel family member 5
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATRAID all-trans retinoic acid-induced differentiation factor
BAG4 BCL2-associated athanogene 4
BARX2 BARX homeobox 2
BAX BCL2-associated X protein
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
BDKRB1 bradykinin receptor B1
BHLHE41 basic helix-loop-helix family, member e41
BPHL biphenyl hydrolase-like (serine hydrolase)
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1
C11ORF45 chromosome 11 open reading frame 45
C14ORF79 chromosome 14 open reading frame 79
C16ORF62 chromosome 16 open reading frame 62
C17ORF50 chromosome 17 open reading frame 50
C1ORF53 chromosome 1 open reading frame 53
C2ORF16 chromosome 2 open reading frame 16
C2ORF83 chromosome 2 open reading frame 83
C4ORF33 chromosome 4 open reading frame 33
C4ORF36 chromosome 4 open reading frame 36
C7ORF49 chromosome 7 open reading frame 49
C8ORF33 chromosome 8 open reading frame 33
C8ORF37 chromosome 8 open reading frame 37
CA12 carbonic anhydrase XII
CALML3 calmodulin-like 3
CALML5 calmodulin-like 5
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CCDC106 coiled-coil domain containing 106
CCDC71 coiled-coil domain containing 71
CCDC85B coiled-coil domain containing 85B
CCR3 chemokine (C-C motif) receptor 3
CD300A CD300a molecule
CD36 CD36 molecule (thrombospondin receptor)
CD58 CD58 molecule
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CFHR1 complement factor H-related 1
CGREF1 cell growth regulator with EF-hand domain 1
CHODL-AS1 CHODL antisense RNA 1
CHRAC1 chromatin accessibility complex 1
CLCA2 chloride channel accessory 2
CLCA3P chloride channel accessory 3, pseudogene
CLCA4 chloride channel accessory 4
CLCN1 chloride channel, voltage-sensitive 1
CMTM2 CKLF-like MARVEL transmembrane domain containing 2
CNGB3 cyclic nucleotide gated channel beta 3
COA7 cytochrome c oxidase assembly factor 7 (putative)
COMMD5 COMM domain containing 5
CSMD3 CUB and Sushi multiple domains 3
CTU1 cytosolic thiouridylase subunit 1
CXCL6 chemokine (C-X-C motif) ligand 6
CXCR2 chemokine (C-X-C motif) receptor 2
CYC1 cytochrome c-1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DAD1 defender against cell death 1
DCAF13 DDB1 and CUL4 associated factor 13
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DERL1 derlin 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DHRS4-AS1 DHRS4 antisense RNA 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DNAAF2 dynein, axonemal, assembly factor 2
DPY19L4 dpy-19-like 4 (C. elegans)
DPYD dihydropyrimidine dehydrogenase
DQX1 DEAQ box RNA-dependent ATPase 1
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
DUSP5P1 dual specificity phosphatase 5 pseudogene 1
EBAG9 estrogen receptor binding site associated, antigen, 9
EEF1B2 eukaryotic translation elongation factor 1 beta 2
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFR3A EFR3 homolog A (S. cerevisiae)
EIF3E eukaryotic translation initiation factor 3, subunit E
ELMOD2 ELMO/CED-12 domain containing 2
EPHA1 EPH receptor A1
ERCC8 excision repair cross-complementation group 8
ERGIC3 ERGIC and golgi 3
EVA1A eva-1 homolog A (C. elegans)
EXOC4 exocyst complex component 4
EXOSC4 exosome component 4
EXT1 exostosin glycosyltransferase 1
FAM102B family with sequence similarity 102, member B
FAM110C family with sequence similarity 110, member C
FAM131B family with sequence similarity 131, member B
FAM3C family with sequence similarity 3, member C
FAM49B family with sequence similarity 49, member B
FAM83H family with sequence similarity 83, member H
FAM86B2 family with sequence similarity 86, member B2
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FKBP10 FK506 binding protein 10, 65 kDa
FLRT2 fibronectin leucine rich transmembrane protein 2
FUZ fuzzy planar cell polarity protein
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GEMIN7 gem (nuclear organelle) associated protein 7
GGT7 gamma-glutamyltransferase 7
GLDC glycine dehydrogenase (decarboxylating)
GLMP glycosylated lysosomal membrane protein
GLRA1 glycine receptor, alpha 1
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GOLPH3L golgi phosphoprotein 3-like
GPAA1 glycosylphosphatidylinositol anchor attachment 1
GPR25 G protein-coupled receptor 25
GPR34 G protein-coupled receptor 34
GPR39 G protein-coupled receptor 39
GPR82 G protein-coupled receptor 82
GPX1 glutathione peroxidase 1
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
GSTK1 glutathione S-transferase kappa 1
HES4 hes family bHLH transcription factor 4
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HNRNPF heterogeneous nuclear ribonucleoprotein F
HOXA3 homeobox A3
HSF1 heat shock transcription factor 1
HTN3 histatin 3
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFITM1 interferon induced transmembrane protein 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNA6 interferon, alpha 6
IFNE interferon, epsilon
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IFT46 intraflagellar transport 46
IL4R interleukin 4 receptor
INO80B INO80 complex subunit B
INTS5 integrator complex subunit 5
INTS8 integrator complex subunit 8
IPO11 importin 11
IRS1 insulin receptor substrate 1
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2
JMJD4 jumonji domain containing 4
JOSD2 Josephin domain containing 2
JRK Jrk homolog (mouse)
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA0196 KIAA0196
KIAA1429 KIAA1429
KIAA1875 KIAA1875
LAPTM4B lysosomal protein transmembrane 4 beta
LETM2 leucine zipper-EF-hand containing transmembrane protein 2
LINC00174 long intergenic non-protein coding RNA 174
LOC100133669 uncharacterized LOC100133669
LOC285692 uncharacterized LOC285692
LOC374443 C-type lectin domain family 2, member D pseudogene
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRRC14 leucine rich repeat containing 14
LRRC39 leucine rich repeat containing 39
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LY6D lymphocyte antigen 6 complex, locus D
LY6E lymphocyte antigen 6 complex, locus E
LY6K lymphocyte antigen 6 complex, locus K
MAB21L3 mab-21-like 3 (C. elegans)
MAF1 MAF1 homolog (S. cerevisiae)
MANBAL mannosidase, beta A, lysosomal-like
MAST4 microtubule associated serine/threonine kinase family member 4
MCTP1 multiple C2 domains, transmembrane 1
MDP1 magnesium-dependent phosphatase 1
MECR mitochondrial trans-2-enoyl-CoA reductase
MED28 mediator complex subunit 28
MED6 mediator complex subunit 6
METAP1 methionyl aminopeptidase 1
METTL2B methyltransferase like 2B
MFSD3 major facilitator superfamily domain containing 3
MIB2 mindbomb E3 ubiquitin protein ligase 2
MMP28 matrix metallopeptidase 28
MOSPD3 motile sperm domain containing 3
MR1 major histocompatibility complex, class I-related
MRPL11 mitochondrial ribosomal protein L11
MRPL16 mitochondrial ribosomal protein L16
MRPL49 mitochondrial ribosomal protein L49
MRPS33 mitochondrial ribosomal protein S33
MTDH metadherin
MTFR1 mitochondrial fission regulator 1
MTSS1 metastasis suppressor 1
MUS81 MUS81 structure-specific endonuclease subunit
NAGK N-acetylglucosamine kinase
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NAT14 N-acetyltransferase 14 (GCN5-related, putative)
NCF1C neutrophil cytosolic factor 1C pseudogene
NCOA4 nuclear receptor coactivator 4
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NET1 neuroepithelial cell transforming 1
NEURL2 neuralized E3 ubiquitin protein ligase 2
NOVA1 neuro-oncological ventral antigen 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NSMCE1 non-SMC element 1 homolog (S. cerevisiae)
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
NT5C 5', 3'-nucleotidase, cytosolic
NTAN1 N-terminal asparagine amidase
NTS neurotensin
NUBPL nucleotide binding protein-like
NUDCD1 NudC domain containing 1
OASL 2'-5'-oligoadenylate synthetase-like
OPN3 opsin 3
OR2A2 olfactory receptor, family 2, subfamily A, member 2
OR7D2 olfactory receptor, family 7, subfamily D, member 2
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2
OST4 oligosaccharyltransferase 4 homolog (S. cerevisiae)
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PABPC1 poly(A) binding protein, cytoplasmic 1
PABPC3 poly(A) binding protein, cytoplasmic 3
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARP12 poly (ADP-ribose) polymerase family, member 12
PARP8 poly (ADP-ribose) polymerase family, member 8
PCDHA4 protocadherin alpha 4
PCDHGA7 protocadherin gamma subfamily A, 7
PCGF1 polycomb group ring finger 1
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PEX2 peroxisomal biogenesis factor 2
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PITX1 paired-like homeodomain 1
PLB1 phospholipase B1
PLEK2 pleckstrin 2
PLTP phospholipid transfer protein
PNKP polynucleotide kinase 3'-phosphatase
POLR2G polymerase (RNA) II (DNA directed) polypeptide G
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
POT1 protection of telomeres 1
PPA2 pyrophosphatase (inorganic) 2
PPAPDC1B phosphatidic acid phosphatase type 2 domain containing 1B
PPM1N protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
PPP4C protein phosphatase 4, catalytic subunit
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PRDM8 PR domain containing 8
PRR16 proline rich 16
PRR7 proline rich 7 (synaptic)
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRTFDC1 phosphoribosyl transferase domain containing 1
PTK2 protein tyrosine kinase 2
PUF60 poly-U binding splicing factor 60KDa
PVT1 Pvt1 oncogene (non-protein coding)
PYCRL pyrroline-5-carboxylate reductase-like
RAD54B RAD54 homolog B (S. cerevisiae)
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
RCE1 Ras converting CAAX endopeptidase 1
RGS14 regulator of G-protein signaling 14
RHOC ras homolog family member C
RIN1 Ras and Rab interactor 1
RMDN1 regulator of microtubule dynamics 1
RNF139 ring finger protein 139
ROGDI rogdi homolog (Drosophila)
RPL13A ribosomal protein L13a
RPL13AP3 ribosomal protein L13a pseudogene 3
RPL23AP7 ribosomal protein L23a pseudogene 7
RPL30 ribosomal protein L30
RPL8 ribosomal protein L8
RPSAP52 ribosomal protein SA pseudogene 52
RTTN rotatin
S100A2 S100 calcium binding protein A2
SEPW1 selenoprotein W, 1
SFRP4 secreted frizzled-related protein 4
SHARPIN SHANK-associated RH domain interactor
SHISA5 shisa family member 5
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC25A26 solute carrier family 25 (S-adenosylmethionine carrier), member 26
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC35F2 solute carrier family 35, member F2
SLC38A9 solute carrier family 38, member 9
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SMIM12 small integral membrane protein 12
SNORA41 small nucleolar RNA, H/ACA box 41
SNORA71E small nucleolar RNA, H/ACA box 71E
SNX18 sorting nexin 18
SNX31 sorting nexin 31
SPDYC speedy/RINGO cell cycle regulator family member C
SPRYD4 SPRY domain containing 4
SQLE squalene epoxidase
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSBP1 single-stranded DNA binding protein 1, mitochondrial
STAMBPL1 STAM binding protein-like 1
STK16 serine/threonine kinase 16
STK31 serine/threonine kinase 31
STX1A syntaxin 1A (brain)
STX6 syntaxin 6
SYPL1 synaptophysin-like 1
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TAS2R4 taste receptor, type 2, member 4
TAS2R60 taste receptor, type 2, member 60
TATDN1 TatD DNase domain containing 1
TBCK TBC1 domain containing kinase
TBX6 T-box 6
THEM6 thioesterase superfamily member 6
TIGD5 tigger transposable element derived 5
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMED10P1 transmembrane emp24-like trafficking protein 10 (yeast) pseudogene 1
TMEM101 transmembrane protein 101
TMEM105 transmembrane protein 105
TMEM134 transmembrane protein 134
TMEM143 transmembrane protein 143
TMEM160 transmembrane protein 160
TMEM179B transmembrane protein 179B
TMEM216 transmembrane protein 216
TMEM222 transmembrane protein 222
TMEM65 transmembrane protein 65
TMEM67 transmembrane protein 67
TMEM88B transmembrane protein 88B
TMSB10 thymosin beta 10
TMUB1 transmembrane and ubiquitin-like domain containing 1
TMX1 thioredoxin-related transmembrane protein 1
TMX2 thioredoxin-related transmembrane protein 2
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like
TRIM46 tripartite motif containing 46
TRIM47 tripartite motif containing 47
TRIM65 tripartite motif containing 65
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase
TRIQK triple QxxK/R motif containing
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae)
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TRMT5 tRNA methyltransferase 5
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TRPT1 tRNA phosphotransferase 1
TSPAN1 tetraspanin 1
TTC5 tetratricopeptide repeat domain 5
U2AF2 U2 small nuclear RNA auxiliary factor 2
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UQCC3 ubiquinol-cytochrome c reductase complex assembly factor 3
UTP23 UTP23, small subunit (SSU) processome component, homolog (yeast)
VAV3 vav 3 guanine nucleotide exchange factor
VKORC1 vitamin K epoxide reductase complex, subunit 1
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VTI1B vesicle transport through interaction with t-SNAREs 1B
WDR77 WD repeat domain 77
WDR89 WD repeat domain 89
WDR91 WD repeat domain 91
WDYHV1 WDYHV motif containing 1
ZBTB25 zinc finger and BTB domain containing 25
ZBTB3 zinc finger and BTB domain containing 3
ZC3HC1 zinc finger, C3HC-type containing 1
ZFP41 ZFP41 zinc finger protein
ZHX1 zinc fingers and homeoboxes 1
ZNF239 zinc finger protein 239
ZNF252P zinc finger protein 252, pseudogene
ZNF425 zinc finger protein 425
ZNF436 zinc finger protein 436
ZNF485 zinc finger protein 485
ZNF576 zinc finger protein 576
ZNF623 zinc finger protein 623
ZNF688 zinc finger protein 688
ZNF696 zinc finger protein 696
ZNF7 zinc finger protein 7
ZP3 zona pellucida glycoprotein 3 (sperm receptor)
ZYX zyxin

low expression

Symbol Name
MCPH1 microcephalin 1