Lung squamous cell carcinoma_LUSC_TCGA-66-2765-01A-01R-0851-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

416 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-66-2765-01A-01R-0851-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10
ABHD17C abhydrolase domain containing 17C
ACTG1 actin gamma 1
ACTN1 actinin, alpha 1
ACY1 aminoacylase 1
ADA adenosine deaminase
ADGRF4 adhesion G protein-coupled receptor F4
AEN apoptosis enhancing nuclease
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDOA aldolase A, fructose-bisphosphate
AMPD3 adenosine monophosphate deaminase 3
ANAPC15 anaphase promoting complex subunit 15
ANKUB1 ankyrin repeat and ubiquitin domain containing 1
ANXA2 annexin A2
ANXA2P2 annexin A2 pseudogene 2
ANXA8L1 annexin A8-like 1
AP1M1 adaptor-related protein complex 1, mu 1 subunit
AP3B1 adaptor-related protein complex 3, beta 1 subunit
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOL4 apolipoprotein L, 4
APTX aprataxin
ARFIP2 ADP-ribosylation factor interacting protein 2
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF39 Rho guanine nucleotide exchange factor (GEF) 39
ARL2 ADP-ribosylation factor-like 2
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ASB2 ankyrin repeat and SOCS box containing 2
ATL3 atlastin GTPase 3
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BAG1 BCL2-associated athanogene
BAG6 BCL2-associated athanogene 6
BAK1 BCL2-antagonist/killer 1
BATF2 basic leucine zipper transcription factor, ATF-like 2
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BIRC2 baculoviral IAP repeat containing 2
BNC1 basonuclin 1
BRMS1 breast cancer metastasis suppressor 1
BSG basigin (Ok blood group)
BTF3 basic transcription factor 3
C10ORF55 chromosome 10 open reading frame 55
C11ORF24 chromosome 11 open reading frame 24
C11ORF68 chromosome 11 open reading frame 68
C14ORF169 chromosome 14 open reading frame 169
C16ORF62 chromosome 16 open reading frame 62
C17ORF105 chromosome 17 open reading frame 105
C17ORF49 chromosome 17 open reading frame 49
C6ORF47 chromosome 6 open reading frame 47
C9ORF89 chromosome 9 open reading frame 89
CA9 carbonic anhydrase IX
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CAPN1 calpain 1, (mu/I) large subunit
CAPRIN1 cell cycle associated protein 1
CARD10 caspase recruitment domain family, member 10
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CARS cysteinyl-tRNA synthetase
CCDC107 coiled-coil domain containing 107
CD151 CD151 molecule (Raph blood group)
CD1A CD1a molecule
CD1B CD1b molecule
CD1E CD1e molecule
CD59 CD59 molecule, complement regulatory protein
CDK7 cyclin-dependent kinase 7
CEMIP cell migration inducing protein, hyaluronan binding
CENPQ centromere protein Q
CFL1 cofilin 1 (non-muscle)
CHMP5 charged multivesicular body protein 5
CHODL-AS1 CHODL antisense RNA 1
CHURC1 churchill domain containing 1
CIB1 calcium and integrin binding 1 (calmyrin)
CIDEB cell death-inducing DFFA-like effector b
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
CKMT1A creatine kinase, mitochondrial 1A
CLCA2 chloride channel accessory 2
CLIC1 chloride intracellular channel 1
CLTB clathrin, light chain B
CNGB1 cyclic nucleotide gated channel beta 1
CNN2 calponin 2
COL17A1 collagen, type XVII, alpha 1
COMMD9 COMM domain containing 9
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CREB3 cAMP responsive element binding protein 3
CRIP1 cysteine-rich protein 1 (intestinal)
CSNK1A1 casein kinase 1, alpha 1
CSNK2B casein kinase 2, beta polypeptide
CTSC cathepsin C
CUTA cutA divalent cation tolerance homolog (E. coli)
CYB5R2 cytochrome b5 reductase 2
DAXX death-domain associated protein
DBNL drebrin-like
DCAF4 DDB1 and CUL4 associated factor 4
DCTN2 dynactin 2 (p50)
DCTN3 dynactin 3 (p22)
DDB2 damage-specific DNA binding protein 2, 48kDa
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEPDC7 DEP domain containing 7
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DPP3 dipeptidyl-peptidase 3
ECI2 enoyl-CoA delta isomerase 2
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EEF1A1P9 eukaryotic translation elongation factor 1 alpha 1 pseudogene 9
EEF1G eukaryotic translation elongation factor 1 gamma
EEF2 eukaryotic translation elongation factor 2
EFHD2 EF-hand domain family, member D2
EFTUD1 elongation factor Tu GTP binding domain containing 1
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4E2 eukaryotic translation initiation factor 4E family member 2
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
ELP4 elongator acetyltransferase complex subunit 4
ENO1 enolase 1, (alpha)
EPS8L2 EPS8-like 2
ESD esterase D
ESRRA estrogen-related receptor alpha
ETHE1 ethylmalonic encephalopathy 1
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM182A family with sequence similarity 182, member A
FAM214B family with sequence similarity 214, member B
FANCG Fanconi anemia, complementation group G
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial
FAT2 FAT atypical cadherin 2
FBLIM1 filamin binding LIM protein 1
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF11 fibroblast growth factor 11
FHL3 four and a half LIM domains 3
FLOT1 flotillin 1
FLOT2 flotillin 2
FNTB farnesyltransferase, CAAX box, beta
FOXD1 forkhead box D1
FRMD8 FERM domain containing 8
FSCN1 fascin actin-bundling protein 1
GALE UDP-galactose-4-epimerase
GBA2 glucosidase, beta (bile acid) 2
GBP1 guanylate binding protein 1, interferon-inducible
GDI2 GDP dissociation inhibitor 2
GJB5 gap junction protein, beta 5, 31.1kDa
GMPPA GDP-mannose pyrophosphorylase A
GMPR2 guanosine monophosphate reductase 2
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPR153 G protein-coupled receptor 153
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GSTP1 glutathione S-transferase pi 1
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
HCG4 HLA complex group 4 (non-protein coding)
HCP5 HLA complex P5 (non-protein coding)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HINT2 histidine triad nucleotide binding protein 2
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-E major histocompatibility complex, class I, E
HMOX2 heme oxygenase 2
HPS6 Hermansky-Pudlak syndrome 6
HRAS Harvey rat sarcoma viral oncogene homolog
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HSPA2 heat shock 70kDa protein 2
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFFO2 intermediate filament family orphan 2
IFI27L1 interferon, alpha-inducible protein 27-like 1
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
IFNGR1 interferon gamma receptor 1
IGFL4 IGF-like family member 4
IL12RB2 interleukin 12 receptor, beta 2
IL20RA interleukin 20 receptor, alpha
IL33 interleukin 33
ILK integrin-linked kinase
INS insulin
INTS5 integrator complex subunit 5
IPO7 importin 7
IQGAP1 IQ motif containing GTPase activating protein 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB4 integrin, beta 4
KAT5 K(lysine) acetyltransferase 5
KATNA1 katanin p60 (ATPase containing) subunit A 1
KCTD14 potassium channel tetramerization domain containing 14
KCTD21 potassium channel tetramerization domain containing 21
KIAA1161 KIAA1161
KIAA1644 KIAA1644
KRT14 keratin 14, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRTAP4-5 keratin associated protein 4-5
L3HYPDH L-3-hydroxyproline dehydratase (trans-)
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LASP1 LIM and SH3 protein 1
LDHA lactate dehydrogenase A
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LGALS1 lectin, galactoside-binding, soluble, 1
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIMA1 LIM domain and actin binding 1
LINC00242 long intergenic non-protein coding RNA 242
LOXL2 lysyl oxidase-like 2
LRRC28 leucine rich repeat containing 28
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MARVELD1 MARVEL domain containing 1
MDFI MyoD family inhibitor
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MMP1 matrix metallopeptidase 1
MMP10 matrix metallopeptidase 10
MOB2 MOB kinase activator 2
MOB3A MOB kinase activator 3A
MORF4L1 mortality factor 4 like 1
MRGPRX3 MAS-related GPR, member X3
MRPL17 mitochondrial ribosomal protein L17
MRPL2 mitochondrial ribosomal protein L2
MRPS11 mitochondrial ribosomal protein S11
MRPS18B mitochondrial ribosomal protein S18B
MSH3 mutS homolog 3
MSMP microseminoprotein, prostate associated
MSN moesin
MT1E metallothionein 1E
MTCH1 mitochondrial carrier 1
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MTRF1L mitochondrial translational release factor 1-like
MYOM3 myomesin 3
NAP1L4 nucleosome assembly protein 1-like 4
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
NELFE negative elongation factor complex member E
NOD2 nucleotide-binding oligomerization domain containing 2
NQO2 NAD(P)H dehydrogenase, quinone 2
NRM nurim (nuclear envelope membrane protein)
NT5DC1 5'-nucleotidase domain containing 1
NT5E 5'-nucleotidase, ecto (CD73)
NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22
OOEP oocyte expressed protein
OPTN optineurin
ORC3 origin recognition complex, subunit 3
OSTM1 osteopetrosis associated transmembrane protein 1
OVCA2 ovarian tumor suppressor candidate 2
PANX1 pannexin 1
PARVA parvin, alpha
PC pyruvate carboxylase
PCDHB4 protocadherin beta 4
PCDHGB6 protocadherin gamma subfamily B, 6
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PDLIM1 PDZ and LIM domain 1
PDZK1IP1 PDZK1 interacting protein 1
PEX16 peroxisomal biogenesis factor 16
PFN1 profilin 1
PGAM1 phosphoglycerate mutase 1 (brain)
PGAM4 phosphoglycerate mutase family member 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PKM pyruvate kinase, muscle
PKP3 plakophilin 3
PLAU plasminogen activator, urokinase
PLEK2 pleckstrin 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLIN3 perilipin 3
PLSCR3 phospholipid scramblase 3
PML promyelocytic leukemia
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLR1C polymerase (RNA) I polypeptide C, 30kDa
POLR1E polymerase (RNA) I polypeptide E, 53kDa
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
PPP1R18 protein phosphatase 1, regulatory subunit 18
PRDX5 peroxiredoxin 5
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRKCDBP protein kinase C, delta binding protein
PRPF19 pre-mRNA processing factor 19
PRSS3P2 protease, serine, 3 pseudogene 2
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSMG4 proteasome (prosome, macropain) assembly chaperone 4
PTDSS2 phosphatidylserine synthase 2
PTGES prostaglandin E synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PYGB phosphorylase, glycogen; brain
PYGL phosphorylase, glycogen, liver
RAB1B RAB1B, member RAS oncogene family
RAB38 RAB38, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RARS arginyl-tRNA synthetase
RARS2 arginyl-tRNA synthetase 2, mitochondrial
RBM3 RNA binding motif (RNP1, RRM) protein 3
RBP1 retinol binding protein 1, cellular
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHOC ras homolog family member C
RHOD ras homolog family member D
RHOG ras homolog family member G
RIC8A RIC8 guanine nucleotide exchange factor A
RIN1 Ras and Rab interactor 1
RIN2 Ras and Rab interactor 2
RING1 ring finger protein 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNASE3 ribonuclease, RNase A family, 3
RNF141 ring finger protein 141
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RNH1 ribonuclease/angiogenin inhibitor 1
RP1L1 retinitis pigmentosa 1-like 1
RPL27A ribosomal protein L27a
RPL36AL ribosomal protein L36a-like
RPLP2 ribosomal protein, large, P2
RPP25L ribonuclease P/MRP 25kDa subunit-like
RPS13 ribosomal protein S13
RPS3 ribosomal protein S3
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RPSAP52 ribosomal protein SA pseudogene 52
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
RXRB retinoid X receptor, beta
S100A2 S100 calcium binding protein A2
S100B S100 calcium binding protein B
SCARNA9L small Cajal body-specific RNA 9-like
SEC11A SEC11 homolog A (S. cerevisiae)
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SEPW1 selenoprotein W, 1
SERINC2 serine incorporator 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SF3A2 splicing factor 3a, subunit 2, 66kDa
SFN stratifin
SHC4 SHC (Src homology 2 domain containing) family, member 4
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
SLC38A2 solute carrier family 38, member 2
SMOC1 SPARC related modular calcium binding 1
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SND1 staphylococcal nuclease and tudor domain containing 1
SNORA66 small nucleolar RNA, H/ACA box 66
SNRPC small nuclear ribonucleoprotein polypeptide C
SNX15 sorting nexin 15
SNX3 sorting nexin 3
SNX7 sorting nexin 7
SOX15 SRY (sex determining region Y)-box 15
SPRYD3 SPRY domain containing 3
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STARD5 StAR-related lipid transfer (START) domain containing 5
STK19 serine/threonine kinase 19
STOML2 stomatin (EPB72)-like 2
STX5 syntaxin 5
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TARSL2 threonyl-tRNA synthetase-like 2
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TCP1 t-complex 1
TESK1 testis-specific kinase 1
TGFBI transforming growth factor, beta-induced, 68kDa
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
TLDC1 TBC/LysM-associated domain containing 1
TLN1 talin 1
TM2D3 TM2 domain containing 3
TMEM102 transmembrane protein 102
TMEM109 transmembrane protein 109
TMEM123 transmembrane protein 123
TMEM171 transmembrane protein 171
TMEM8B transmembrane protein 8B
TNC tenascin C
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNS4 tensin 4
TOLLIP toll interacting protein
TPM1 tropomyosin 1 (alpha)
TPM2 tropomyosin 2 (beta)
TPM4 tropomyosin 4
TRAF3IP2 TRAF3 interacting protein 2
TRAPPC1 trafficking protein particle complex 1
TRERF1 transcriptional regulating factor 1
TRIM21 tripartite motif containing 21
TRPT1 tRNA phosphotransferase 1
TSG101 tumor susceptibility 101
TTC23 tetratricopeptide repeat domain 23
TUBB tubulin, beta class I
TUBB6 tubulin, beta 6 class V
TXNDC17 thioredoxin domain containing 17
UBAP1 ubiquitin associated protein 1
UBAP2 ubiquitin associated protein 2
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2
UEVLD UEV and lactate/malate dehyrogenase domains
UNC45A unc-45 homolog A (C. elegans)
VCP valosin containing protein
VIM vimentin
VIMP VCP-interacting membrane selenoprotein
VTI1B vesicle transport through interaction with t-SNAREs 1B
WDR61 WD repeat domain 61
WDR73 WD repeat domain 73
WNT7A wingless-type MMTV integration site family, member 7A
XDH xanthine dehydrogenase
YAP1 Yes-associated protein 1
YIF1A Yip1 interacting factor homolog A (S. cerevisiae)
YIPF3 Yip1 domain family, member 3
ZBTB9 zinc finger and BTB domain containing 9
ZDHHC14 zinc finger, DHHC-type containing 14
ZFPL1 zinc finger protein-like 1
ZNF654 zinc finger protein 654
ZYX zyxin

low expression

Symbol Name
BMPR1A bone morphogenetic protein receptor, type IA