Lung squamous cell carcinoma_LUSC_TCGA-66-2744-01A-01R-0980-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

405 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-66-2744-01A-01R-0980-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACER3 alkaline ceramidase 3
ACTA1 actin, alpha 1, skeletal muscle
ACTBL2 actin, beta-like 2
ADAM19 ADAM metallopeptidase domain 19
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6
AIM2 absent in melanoma 2
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase
ALG8 ALG8, alpha-1,3-glucosyltransferase
AMPD3 adenosine monophosphate deaminase 3
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APEH acylaminoacyl-peptide hydrolase
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASPHD2 aspartate beta-hydroxylase domain containing 2
ATP10D ATPase, class V, type 10D
ATP8B4 ATPase, class I, type 8B, member 4
AURKA aurora kinase A
AXL AXL receptor tyrosine kinase
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BATF2 basic leucine zipper transcription factor, ATF-like 2
BIRC7 baculoviral IAP repeat containing 7
BST2 bone marrow stromal cell antigen 2
C11ORF30 chromosome 11 open reading frame 30
C11ORF58 chromosome 11 open reading frame 58
C19ORF70 chromosome 19 open reading frame 70
C1QC complement component 1, q subcomponent, C chain
C2CD3 C2 calcium-dependent domain containing 3
C4ORF33 chromosome 4 open reading frame 33
C5ORF38 chromosome 5 open reading frame 38
CA3 carbonic anhydrase III
CACNG8 calcium channel, voltage-dependent, gamma subunit 8
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC169 coiled-coil domain containing 169
CCK cholecystokinin
CCL8 chemokine (C-C motif) ligand 8
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CCR1 chemokine (C-C motif) receptor 1
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CD209 CD209 molecule
CD300A CD300a molecule
CD63 CD63 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CDK14 cyclin-dependent kinase 14
CDK2 cyclin-dependent kinase 2
CDR2 cerebellar degeneration-related protein 2, 62kDa
CEP170P1 centrosomal protein 170kDa pseudogene 1
CERKL ceramide kinase-like
CFL1 cofilin 1 (non-muscle)
CHM choroideremia (Rab escort protein 1)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLDN11 claudin 11
CLEC3A C-type lectin domain family 3, member A
CLNS1A chloride channel, nucleotide-sensitive, 1A
CMKLR1 chemerin chemokine-like receptor 1
CMTM3 CKLF-like MARVEL transmembrane domain containing 3
CMTM6 CKLF-like MARVEL transmembrane domain containing 6
CMTM7 CKLF-like MARVEL transmembrane domain containing 7
CNN1 calponin 1, basic, smooth muscle
CNOT10 CCR4-NOT transcription complex, subunit 10
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae)
COG6 component of oligomeric golgi complex 6
COPB1 coatomer protein complex, subunit beta 1
CPA4 carboxypeptidase A4
CRYBB2 crystallin, beta B2
CSRP1 cysteine and glycine-rich protein 1
CTR9 CTR9, Paf1/RNA polymerase II complex component
CTSZ cathepsin Z
CTTN cortactin
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1
CXCR6 chemokine (C-X-C motif) receptor 6
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DAP death-associated protein
DBF4 DBF4 zinc finger
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
DHCR7 7-dehydrocholesterol reductase
DIAPH3 diaphanous-related formin 3
DSE dermatan sulfate epimerase
DUS3L dihydrouridine synthase 3-like (S. cerevisiae)
DUSP9 dual specificity phosphatase 9
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
ELF1 E74-like factor 1 (ets domain transcription factor)
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2
EPSTI1 epithelial stromal interaction 1 (breast)
ERAP2 endoplasmic reticulum aminopeptidase 2
ERCC6L excision repair cross-complementation group 6-like
EXOSC8 exosome component 8
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FADD Fas (TNFRSF6)-associated via death domain
FAM168A family with sequence similarity 168, member A
FAM215A family with sequence similarity 215, member A (non-protein coding)
FAM26F family with sequence similarity 26, member F
FAM46D family with sequence similarity 46, member D
FAM49B family with sequence similarity 49, member B
FAR2 fatty acyl CoA reductase 2
FBLN7 fibulin 7
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCHSD2 FCH and double SH3 domains 2
FGF18 fibroblast growth factor 18
FHL2 four and a half LIM domains 2
FKBP10 FK506 binding protein 10, 65 kDa
FLJ16779 uncharacterized LOC100192386
FOLR2 folate receptor 2 (fetal)
FOXC2 forkhead box C2
FOXO1 forkhead box O1
FPR3 formyl peptide receptor 3
FRMD5 FERM domain containing 5
FRYL FRY-like
FXYD5 FXYD domain containing ion transport regulator 5
FXYD7 FXYD domain containing ion transport regulator 7
GAL galanin/GMAP prepropeptide
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18
GBP1 guanylate binding protein 1, interferon-inducible
GBP2 guanylate binding protein 2, interferon-inducible
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GFI1 growth factor independent 1 transcription repressor
GGCX gamma-glutamyl carboxylase
GLB1 galactosidase, beta 1
GLDC glycine dehydrogenase (decarboxylating)
GLT8D1 glycosyltransferase 8 domain containing 1
GMPR2 guanosine monophosphate reductase 2
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
GNLY granulysin
GPC4 glypican 4
GPR108 G protein-coupled receptor 108
GPR176 G protein-coupled receptor 176
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa
GUCD1 guanylyl cyclase domain containing 1
GUF1 GUF1 GTPase homolog (S. cerevisiae)
GYLTL1B glycosyltransferase-like 1B
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HCAR1 hydroxycarboxylic acid receptor 1
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HEXB hexosaminidase B (beta polypeptide)
HIGD1C HIG1 hypoxia inducible domain family, member 1C
HLA-L major histocompatibility complex, class I, L (pseudogene)
HMGA2 high mobility group AT-hook 2
HMMR hyaluronan-mediated motility receptor (RHAMM)
HN1L hematological and neurological expressed 1-like
HNRNPF heterogeneous nuclear ribonucleoprotein F
HRH1 histamine receptor H1
HSD11B1L hydroxysteroid (11-beta) dehydrogenase 1-like
IFI6 interferon, alpha-inducible protein 6
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
IGF2-AS IGF2 antisense RNA
IGFBP4 insulin-like growth factor binding protein 4
IGFBP7 insulin-like growth factor binding protein 7
IL12RB1 interleukin 12 receptor, beta 1
IL12RB2 interleukin 12 receptor, beta 2
IL24 interleukin 24
IMMT inner membrane protein, mitochondrial
INTS4 integrator complex subunit 4
INTS4P1 integrator complex subunit 4 pseudogene 1
INTS4P2 integrator complex subunit 4 pseudogene 2
IRX1 iroquois homeobox 1
ISG15 ISG15 ubiquitin-like modifier
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB6 integrin, beta 6
ITGB7 integrin, beta 7
ITPRIPL1 inositol 1,4,5-trisphosphate receptor interacting protein-like 1
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCTD14 potassium channel tetramerization domain containing 14
KCTD21 potassium channel tetramerization domain containing 21
KCTD8 potassium channel tetramerization domain containing 8
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR3DP1 killer cell immunoglobulin-like receptor, three domains, pseudogene 1
KLHDC3 kelch domain containing 3
KLHDC7B kelch domain containing 7B
KRT18 keratin 18, type I
LAG3 lymphocyte-activation gene 3
LAP3 leucine aminopeptidase 3
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LIMA1 LIM domain and actin binding 1
LIMS1 LIM and senescent cell antigen-like domains 1
LIMS3 LIM and senescent cell antigen-like domains 3
LIMS3-LOC440895 LIMS3-LOC440895 readthrough
LINC00029 long intergenic non-protein coding RNA 29
LINC00518 long intergenic non-protein coding RNA 518
LIPA lipase A, lysosomal acid, cholesterol esterase
LIPG lipase, endothelial
LIPT2 lipoyl(octanoyl) transferase 2 (putative)
LITAF lipopolysaccharide-induced TNF factor
LMBR1L limb development membrane protein 1-like
LOC100240734 uncharacterized LOC100240734
LOC100240735 uncharacterized LOC100240735
LOC100272216 uncharacterized LOC100272216
LOC284798 uncharacterized LOC284798
LOC285074 anaphase promoting complex subunit 1 pseudogene
LOC400043 uncharacterized LOC400043
LOC643923 uncharacterized LOC643923
LOC645166 lymphocyte-specific protein 1 pseudogene
LONP1 lon peptidase 1, mitochondrial
LOXL3 lysyl oxidase-like 3
LPXN leupaxin
LRRN1 leucine rich repeat neuronal 1
LY6E lymphocyte antigen 6 complex, locus E
MAGT1 magnesium transporter 1
MANF mesencephalic astrocyte-derived neurotrophic factor
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
MDFI MyoD family inhibitor
MEG8 maternally expressed 8 (non-protein coding)
MFAP2 microfibrillar-associated protein 2
MFSD12 major facilitator superfamily domain containing 12
MGARP mitochondria-localized glutamic acid-rich protein
MIA melanoma inhibitory activity
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MICALCL MICAL C-terminal like
MICB MHC class I polypeptide-related sequence B
MMP10 matrix metallopeptidase 10
MMP12 matrix metallopeptidase 12
MRAS muscle RAS oncogene homolog
MRPL21 mitochondrial ribosomal protein L21
MRPL35 mitochondrial ribosomal protein L35
MRPL48 mitochondrial ribosomal protein L48
MRPS31 mitochondrial ribosomal protein S31
MRVI1 murine retrovirus integration site 1 homolog
MT1L metallothionein 1L (gene/pseudogene)
MTRF1 mitochondrial translational release factor 1
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MYDGF myeloid-derived growth factor
MYL9 myosin, light chain 9, regulatory
MYOZ3 myozenin 3
NADSYN1 NAD synthetase 1
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative)
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
NEK6 NIMA-related kinase 6
NEU3 sialidase 3 (membrane sialidase)
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFE2L3 nuclear factor, erythroid 2-like 3
NFXL1 nuclear transcription factor, X-box binding-like 1
NGFR nerve growth factor receptor
NHLRC3 NHL repeat containing 3
NKAIN4 Na+/K+ transporting ATPase interacting 4
NKX2-6 NK2 homeobox 6
NME6 NME/NM23 nucleoside diphosphate kinase 6
NMI N-myc (and STAT) interactor
NOA1 nitric oxide associated 1
NOG noggin
NR1D1 nuclear receptor subfamily 1, group D, member 1
NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1
NUAK1 NUAK family, SNF1-like kinase, 1
NUCB2 nucleobindin 2
OCIAD1 OCIA domain containing 1
OCIAD2 OCIA domain containing 2
OR2C1 olfactory receptor, family 2, subfamily C, member 1
OR52N2 olfactory receptor, family 52, subfamily N, member 2
OSBPL10 oxysterol binding protein-like 10
OSGEP O-sialoglycoprotein endopeptidase
PAAF1 proteasomal ATPase-associated factor 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARVA parvin, alpha
PBDC1 polysaccharide biosynthesis domain containing 1
PDCD1LG2 programmed cell death 1 ligand 2
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDGFA platelet-derived growth factor alpha polypeptide
PDS5A PDS5 cohesin associated factor A
PDS5B PDS5 cohesin associated factor B
PGK1 phosphoglycerate kinase 1
PGM2L1 phosphoglucomutase 2-like 1
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLSCR1 phospholipid scramblase 1
PMEPA1 prostate transmembrane protein, androgen induced 1
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2
PPME1 protein phosphatase methylesterase 1
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PPP4R2 protein phosphatase 4, regulatory subunit 2
PRCP prolylcarboxypeptidase (angiotensinase C)
PRF1 perforin 1 (pore forming protein)
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
PRPH2 peripherin 2 (retinal degeneration, slow)
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSPC1 paraspeckle component 1
PTCD3 pentatricopeptide repeat domain 3
RAB6A RAB6A, member RAS oncogene family
RAB6C RAB6C, member RAS oncogene family
RASL11B RAS-like, family 11, member B
RELT RELT tumor necrosis factor receptor
RFC1 replication factor C (activator 1) 1, 145kDa
RGAG4 retrotransposon gag domain containing 4
RIC1 RAB6A GEF complex partner 1
RIPK3 receptor-interacting serine-threonine kinase 3
RNASE6 ribonuclease, RNase A family, k6
RNF141 ring finger protein 141
RNF169 ring finger protein 169
RNF181 ring finger protein 181
RPL36 ribosomal protein L36
RPL9 ribosomal protein L9
RPS13 ribosomal protein S13
RPS3 ribosomal protein S3
RRP36 ribosomal RNA processing 36 homolog (S. cerevisiae)
RSF1 remodeling and spacing factor 1
SALL4 spalt-like transcription factor 4
SAMHD1 SAM domain and HD domain 1
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SH2D2A SH2 domain containing 2A
SH2D3A SH2 domain containing 3A
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHISA5 shisa family member 5
SIAH3 siah E3 ubiquitin protein ligase family member 3
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC16A12 solute carrier family 16, member 12
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SMIM24 small integral membrane protein 24
SOHLH1 spermatogenesis and oogenesis specific basic helix-loop-helix 1
SP110 SP110 nuclear body protein
SPATS2 spermatogenesis associated, serine-rich 2
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SPDYE4 speedy/RINGO cell cycle regulator family member E4
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
STARD10 StAR-related lipid transfer (START) domain containing 10
STAT2 signal transducer and activator of transcription 2, 113kDa
STK38L serine/threonine kinase 38 like
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
SUCLG1 succinate-CoA ligase, alpha subunit
SULF2 sulfatase 2
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TM9SF1 transmembrane 9 superfamily member 1
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMEM229B transmembrane protein 229B
TMEM261 transmembrane protein 261
TMSB10 thymosin beta 10
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TOMM34 translocase of outer mitochondrial membrane 34
TOR4A torsin family 4, member A
TOX2 TOX high mobility group box family member 2
TPM1 tropomyosin 1 (alpha)
TRABD2A TraB domain containing 2A
TRIM21 tripartite motif containing 21
TRIM32 tripartite motif containing 32
TRIP10 thyroid hormone receptor interactor 10
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1
TSKU tsukushi, small leucine rich proteoglycan
TSPAN2 tetraspanin 2
TTC9C tetratricopeptide repeat domain 9C
TUBA1B tubulin, alpha 1b
UBE2K ubiquitin-conjugating enzyme E2K
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UFM1 ubiquitin-fold modifier 1
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
USP39 ubiquitin specific peptidase 39
USP47 ubiquitin specific peptidase 47
UTS2 urotensin 2
UVRAG UV radiation resistance associated
VAMP8 vesicle-associated membrane protein 8
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VEGFC vascular endothelial growth factor C
WARS tryptophanyl-tRNA synthetase
XRRA1 X-ray radiation resistance associated 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZBED5 zinc finger, BED-type containing 5
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate)
ZMYM5 zinc finger, MYM-type 5
ZNF22 zinc finger protein 22
ZNF281 zinc finger protein 281
ZNF880 zinc finger protein 880