Lung squamous cell carcinoma_LUSC_TCGA-66-2742-01A-01R-0980-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

409 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-66-2742-01A-01R-0980-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ABI1 abl-interactor 1
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADAM10 ADAM metallopeptidase domain 10
ADAM28 ADAM metallopeptidase domain 28
ADAM32 ADAM metallopeptidase domain 32
ADD3 adducin 3 (gamma)
ADGRG3 adhesion G protein-coupled receptor G3
ADGRL3 adhesion G protein-coupled receptor L3
ADGRV1 adhesion G protein-coupled receptor V1
AHR aryl hydrocarbon receptor
AKAP3 A kinase (PRKA) anchor protein 3
ALCAM activated leukocyte cell adhesion molecule
ALX1 ALX homeobox 1
ANKMY2 ankyrin repeat and MYND domain containing 2
ANKRD36BP1 ankyrin repeat domain 36B pseudogene 1
ANKRD50 ankyrin repeat domain 50
ANKUB1 ankyrin repeat and ubiquitin domain containing 1
APH1A APH1A gamma secretase subunit
ARHGAP36 Rho GTPase activating protein 36
ARL4D ADP-ribosylation factor-like 4D
ARMC8 armadillo repeat containing 8
ARNT aryl hydrocarbon receptor nuclear translocator
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASTE1 asteroid homolog 1 (Drosophila)
ATE1 arginyltransferase 1
ATF6 activating transcription factor 6
ATP13A3 ATPase type 13A3
ATP13A5 ATPase type 13A5
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
ATR ATR serine/threonine kinase
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
BBX bobby sox homolog (Drosophila)
BCL6 B-cell CLL/lymphoma 6
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BROX BRO1 domain and CAAX motif containing
C10ORF120 chromosome 10 open reading frame 120
C10ORF88 chromosome 10 open reading frame 88
C17ORF62 chromosome 17 open reading frame 62
C1ORF204 chromosome 1 open reading frame 204
C1ORF43 chromosome 1 open reading frame 43
C3ORF33 chromosome 3 open reading frame 33
CACUL1 CDK2-associated, cullin domain 1
CALU calumenin
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCDC15 coiled-coil domain containing 15
CCDC185 coiled-coil domain containing 185
CCDC186 coiled-coil domain containing 186
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CCR3 chemokine (C-C motif) receptor 3
CD3EAP CD3e molecule, epsilon associated protein
CDC73 cell division cycle 73
CDH26 cadherin 26
CEP350 centrosomal protein 350kDa
CEP63 centrosomal protein 63kDa
CERS2 ceramide synthase 2
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
CLDN1 claudin 1
CLDND1 claudin domain containing 1
CLTC clathrin, heavy chain (Hc)
CMTM2 CKLF-like MARVEL transmembrane domain containing 2
COMMD2 COMM domain containing 2
COPA coatomer protein complex, subunit alpha
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
CPLX4 complexin 4
CRLF3 cytokine receptor-like factor 3
CSMD1 CUB and Sushi multiple domains 1
CT83 cancer/testis antigen 83
CTBP2 C-terminal binding protein 2
CTBS chitobiase, di-N-acetyl-
CTSB cathepsin B
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
DAP3 death associated protein 3
DCAF6 DDB1 and CUL4 associated factor 6
DCLRE1A DNA cross-link repair 1A
DEDD death effector domain containing
DENND2C DENN/MADD domain containing 2C
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DMRTA2 DMRT-like family A2
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DPYD dihydropyrimidine dehydrogenase
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EFCAB7 EF-hand calcium binding domain 7
EFNA1 ephrin-A1
EIF1 eukaryotic translation initiation factor 1
EIF2A eukaryotic translation initiation factor 2A, 65kDa
ENAH enabled homolog (Drosophila)
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
EPHA4 EPH receptor A4
ESYT2 extended synaptotagmin-like protein 2
EYA1 EYA transcriptional coactivator and phosphatase 1
EYA2 EYA transcriptional coactivator and phosphatase 2
F11R F11 receptor
FAM120C family with sequence similarity 120C
FAM134C family with sequence similarity 134, member C
FAM157A family with sequence similarity 157, member A
FAM175B family with sequence similarity 175, member B
FAM24B family with sequence similarity 24, member B
FAM45A family with sequence similarity 45, member A
FAM45B family with sequence similarity 45, member A pseudogene
FAM73A family with sequence similarity 73, member A
FBXO47 F-box protein 47
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FMO4 flavin containing monooxygenase 4
FMO9P flavin containing monooxygenase 9 pseudogene
FN3KRP fructosamine 3 kinase related protein
FNDC3B fibronectin type III domain containing 3B
FOXD1 forkhead box D1
FPGT fucose-1-phosphate guanylyltransferase
FYTTD1 forty-two-three domain containing 1
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GBA glucosidase, beta, acid
GFM1 G elongation factor, mitochondrial 1
GID8 GID complex subunit 8
GK5 glycerol kinase 5 (putative)
GLIPR1L2 GLI pathogenesis-related 1 like 2
GLIS3 GLIS family zinc finger 3
GLUL glutamate-ammonia ligase
GOLPH3L golgi phosphoprotein 3-like
GON4L gon-4-like (C. elegans)
GOSR1 golgi SNAP receptor complex member 1
GOSR2 golgi SNAP receptor complex member 2
GOT1L1 glutamic-oxaloacetic transaminase 1-like 1
GPALPP1 GPALPP motifs containing 1
GPR85 G protein-coupled receptor 85
GRB10 growth factor receptor-bound protein 10
HAP1 huntingtin-associated protein 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HFE hemochromatosis
HIAT1 hippocampus abundant transcript 1
HIST2H2BF histone cluster 2, H2bf
HLTF helicase-like transcription factor
HPS3 Hermansky-Pudlak syndrome 3
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IFI16 interferon, gamma-inducible protein 16
IFT80 intraflagellar transport 80
IFT81 intraflagellar transport 81
IGFBP3 insulin-like growth factor binding protein 3
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL12RB2 interleukin 12 receptor, beta 2
IL1RAP interleukin 1 receptor accessory protein
ILDR1 immunoglobulin-like domain containing receptor 1
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IPP intracisternal A particle-promoted polypeptide
IQCF6 IQ motif containing F6
IRS1 insulin receptor substrate 1
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
ITCH itchy E3 ubiquitin protein ligase
ITGB8 integrin, beta 8
JRKL JRK-like
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KIAA1107 KIAA1107
KIAA2022 KIAA2022
KLHL20 kelch-like family member 20
KLHL34 kelch-like family member 34
KLLN killin, p53-regulated DNA replication inhibitor
KRT19 keratin 19, type I
KRT23 keratin 23, type I
KRTAP5-6 keratin associated protein 5-6
LEKR1 leucine, glutamate and lysine rich 1
LIPG lipase, endothelial
LMLN leishmanolysin-like (metallopeptidase M8 family)
LOC643923 uncharacterized LOC643923
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRRC40 leucine rich repeat containing 40
LRRC8B leucine rich repeat containing 8 family, member B
LRRIQ4 leucine-rich repeats and IQ motif containing 4
MARCKS myristoylated alanine-rich protein kinase C substrate
MCMBP minichromosome maintenance complex binding protein
MCPH1 microcephalin 1
MED14 mediator complex subunit 14
METTL10 methyltransferase like 10
METTL4 methyltransferase like 4
MFSD1 major facilitator superfamily domain containing 1
MIDN midnolin
MLF1 myeloid leukemia factor 1
MLX MLX, MAX dimerization protein
MR1 major histocompatibility complex, class I-related
MRPL24 mitochondrial ribosomal protein L24
MRPS14 mitochondrial ribosomal protein S14
MSL2 male-specific lethal 2 homolog (Drosophila)
MT1X metallothionein 1X
MTUS1 microtubule associated tumor suppressor 1
MUC1 mucin 1, cell surface associated
MUC4 mucin 4, cell surface associated
MXI1 MAX interactor 1, dimerization protein
NBEA neurobeachin
NCK1 NCK adaptor protein 1
NCSTN nicastrin
NDRG3 NDRG family member 3
NELL1 NEL-like 1 (chicken)
NHLRC2 NHL repeat containing 2
NIT1 nitrilase 1
NMD3 NMD3 ribosome export adaptor
NME7 NME/NM23 family member 7
NOTCH3 notch 3
NPEPPS aminopeptidase puromycin sensitive
NSF N-ethylmaleimide-sensitive factor
NTNG1 netrin G1
NTS neurotensin
OCLM oculomedin
OTX2 orthodenticle homeobox 2
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PAX7 paired box 7
PCDHA4 protocadherin alpha 4
PCDHB12 protocadherin beta 12
PCDHB14 protocadherin beta 14
PCDHB4 protocadherin beta 4
PCDHB5 protocadherin beta 5
PCDHB8 protocadherin beta 8
PCDHGB7 protocadherin gamma subfamily B, 7
PCNP PEST proteolytic signal containing nuclear protein
PEX19 peroxisomal biogenesis factor 19
PF4V1 platelet factor 4 variant 1
PFN2 profilin 2
PGM2L1 phosphoglucomutase 2-like 1
PIBF1 progesterone immunomodulatory binding factor 1
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PIGM phosphatidylinositol glycan anchor biosynthesis, class M
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PIGU phosphatidylinositol glycan anchor biosynthesis, class U
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PIPSL PIP5K1A and PSMD4-like, pseudogene
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAT plasminogen activator, tissue
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLS1 plastin 1
PLSCR1 phospholipid scramblase 1
PLSCR2 phospholipid scramblase 2
PLSCR4 phospholipid scramblase 4
POGK pogo transposable element with KRAB domain
POM121L8P POM121 transmembrane nucleoporin-like 8 pseudogene
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
PPM1J protein phosphatase, Mg2+/Mn2+ dependent, 1J
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PPP1R2P3 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 3
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PRCC papillary renal cell carcinoma (translocation-associated)
PRIMPOL primase and polymerase (DNA-directed)
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKY protein kinase, Y-linked, pseudogene
PRMT6 protein arginine methyltransferase 6
PRSS21 protease, serine, 21 (testisin)
PRSS22 protease, serine, 22
PRSS23 protease, serine, 23
PRUNE prune exopolyphosphatase
PTGFR prostaglandin F receptor (FP)
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
PVRL3 poliovirus receptor-related 3
PYGO2 pygopus family PHD finger 2
RABGAP1L RAB GTPase activating protein 1-like
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
RBMXL1 RNA binding motif protein, X-linked-like 1
RIMS1 regulating synaptic membrane exocytosis 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF13 ring finger protein 13
RNF2 ring finger protein 2
RPL18A ribosomal protein L18a
RPL21 ribosomal protein L21
RPL39L ribosomal protein L39-like
RPN1 ribophorin I
RSRC1 arginine/serine-rich coiled-coil 1
RUFY2 RUN and FYVE domain containing 2
RUSC1 RUN and SH3 domain containing 1
RWDD3 RWD domain containing 3
RYK receptor-like tyrosine kinase
S100A11 S100 calcium binding protein A11
S100PBP S100P binding protein
SASS6 spindle assembly 6 homolog (C. elegans)
SCAMP3 secretory carrier membrane protein 3
SCYL3 SCY1-like 3 (S. cerevisiae)
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SEC23IP SEC23 interacting protein
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SENP5 SUMO1/sentrin specific peptidase 5
SENP7 SUMO1/sentrin specific peptidase 7
SEPT7 septin 7
SEPT9 septin 9
SERINC3 serine incorporator 3
SERP1 stress-associated endoplasmic reticulum protein 1
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SH3GLB1 SH3-domain GRB2-like endophilin B1
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SHOX2 short stature homeobox 2
SIX2 SIX homeobox 2
SLC25A44 solute carrier family 25, member 44
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC30A7 solute carrier family 30 (zinc transporter), member 7
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC35G2 solute carrier family 35, member G2
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC44A5 solute carrier family 44, member 5
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9C2 solute carrier family 9, member C2 (putative)
SLITRK5 SLIT and NTRK-like family, member 5
SMC3 structural maintenance of chromosomes 3
SMNDC1 survival motor neuron domain containing 1
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SNAPIN SNAP-associated protein
SNORA18 small nucleolar RNA, H/ACA box 18
SNX27 sorting nexin family member 27
SOAT1 sterol O-acyltransferase 1
SP4 Sp4 transcription factor
SPERT spermatid associated
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SSR2 signal sequence receptor, beta (translocon-associated protein beta)
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STIM2 stromal interaction molecule 2
STK31 serine/threonine kinase 31
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
STX6 syntaxin 6
SUCO SUN domain containing ossification factor
SWT1 SWT1 RNA endoribonuclease homolog (S. cerevisiae)
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TADA1 transcriptional adaptor 1
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TARM1 T cell-interacting, activating receptor on myeloid cells 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TEDDM1 transmembrane epididymal protein 1
TEFM transcription elongation factor, mitochondrial
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TFG TRK-fused gene
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THEM4 thioesterase superfamily member 4
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TIPRL TOR signaling pathway regulator
TM2D1 TM2 domain containing 1
TMEM123 transmembrane protein 123
TMEM234 transmembrane protein 234
TMEM39A transmembrane protein 39A
TMEM99 transmembrane protein 99
TMPRSS4 transmembrane protease, serine 4
TMPRSS7 transmembrane protease, serine 7
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOP1 topoisomerase (DNA) I
TOP1P1 topoisomerase (DNA) I pseudogene 1
TOR1AIP1 torsin A interacting protein 1
TOR1AIP2 torsin A interacting protein 2
TOR3A torsin family 3, member A
TPR translocated promoter region, nuclear basket protein
TPTE2P1 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 1
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TROVE2 TROVE domain family, member 2
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRUB1 TruB pseudouridine (psi) synthase family member 1
TSHZ3 teashirt zinc finger homeobox 3
TSSK6 testis-specific serine kinase 6
TWISTNB TWIST neighbor
U2SURP U2 snRNP-associated SURP domain containing
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
UHMK1 U2AF homology motif (UHM) kinase 1
UPK1B uroplakin 1B
USP33 ubiquitin specific peptidase 33
VAMP4 vesicle-associated membrane protein 4
VAV3 vav 3 guanine nucleotide exchange factor
VEZF1 vascular endothelial zinc finger 1
WDR5B WD repeat domain 5B
WWTR1 WW domain containing transcription regulator 1
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
XPO7 exportin 7
XRN1 5'-3' exoribonuclease 1
YY1AP1 YY1 associated protein 1
ZBTB11 zinc finger and BTB domain containing 11
ZBTB44 zinc finger and BTB domain containing 44
ZDHHC6 zinc finger, DHHC-type containing 6
ZFP14 ZFP14 zinc finger protein
ZMYM1 zinc finger, MYM-type 1
ZNF112 zinc finger protein 112
ZNF143 zinc finger protein 143
ZNF285 zinc finger protein 285
ZNF333 zinc finger protein 333
ZNF506 zinc finger protein 506
ZNF585B zinc finger protein 585B
ZNF630 zinc finger protein 630
ZNF648 zinc finger protein 648
ZNF681 zinc finger protein 681
ZNF687 zinc finger protein 687

low expression

Symbol Name
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)