Lung squamous cell carcinoma_LUSC_TCGA-66-2727-01A-01R-0980-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

400 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-66-2727-01A-01R-0980-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ABRACL ABRA C-terminal like
ACAT2 acetyl-CoA acetyltransferase 2
ADCY8 adenylate cyclase 8 (brain)
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ADHFE1 alcohol dehydrogenase, iron containing, 1
AFG3L2 AFG3-like AAA ATPase 2
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AKR1C6P aldo-keto reductase family 1, member C6, pseudogene
ANAPC10 anaphase promoting complex subunit 10
ANXA7 annexin A7
API5 apoptosis inhibitor 5
ARL13B ADP-ribosylation factor-like 13B
ARRDC3 arrestin domain containing 3
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
ASF1A anti-silencing function 1A histone chaperone
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
ATG3 autophagy related 3
ATG5 autophagy related 5
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATR ATR serine/threonine kinase
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BEX2 brain expressed X-linked 2
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BOD1 biorientation of chromosomes in cell division 1
BRIX1 BRX1, biogenesis of ribosomes
BST1 bone marrow stromal cell antigen 1
C3ORF17 chromosome 3 open reading frame 17
C4ORF29 chromosome 4 open reading frame 29
C5ORF30 chromosome 5 open reading frame 30
C9ORF89 chromosome 9 open reading frame 89
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAPN7 calpain 7
CARS cysteinyl-tRNA synthetase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CBLN2 cerebellin 2 precursor
CBR1 carbonyl reductase 1
CBR3 carbonyl reductase 3
CCDC138 coiled-coil domain containing 138
CCDC28A coiled-coil domain containing 28A
CCDC36 coiled-coil domain containing 36
CCDC59 coiled-coil domain containing 59
CCNA1 cyclin A1
CCNA2 cyclin A2
CCNB1 cyclin B1
CCNB2 cyclin B2
CD274 CD274 molecule
CDC20 cell division cycle 20
CDC40 cell division cycle 40
CDK1 cyclin-dependent kinase 1
CDYL chromodomain protein, Y-like
CENPN centromere protein N
CEP76 centrosomal protein 76kDa
CEP85 centrosomal protein 85kDa
CEP97 centrosomal protein 97kDa
CES1 carboxylesterase 1
CISD1 CDGSH iron sulfur domain 1
CLDND1 claudin domain containing 1
CLINT1 clathrin interactor 1
CLYBL citrate lyase beta like
CMSS1 cms1 ribosomal small subunit homolog (yeast)
CNBP CCHC-type zinc finger, nucleic acid binding protein
CNST consortin, connexin sorting protein
COMMD2 COMM domain containing 2
COQ3 coenzyme Q3 methyltransferase
CORO1C coronin, actin binding protein, 1C
CORO2A coronin, actin binding protein, 2A
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRMP1 collapsin response mediator protein 1
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTPS1 CTP synthase 1
CXORF56 chromosome X open reading frame 56
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
DEPDC1 DEP domain containing 1
DHFR dihydrofolate reductase
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36
DIRAS2 DIRAS family, GTP-binding RAS-like 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNM1P46 dynamin 1 pseudogene 46
ECI1 enoyl-CoA delta isomerase 1
EIF1B eukaryotic translation initiation factor 1B
EIF3J eukaryotic translation initiation factor 3, subunit J
EIF5 eukaryotic translation initiation factor 5
EPGN epithelial mitogen
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPRS glutamyl-prolyl-tRNA synthetase
ERI3 ERI1 exoribonuclease family member 3
ERMARD ER membrane-associated RNA degradation
ETFA electron-transfer-flavoprotein, alpha polypeptide
EYA4 EYA transcriptional coactivator and phosphatase 4
FAF1 Fas (TNFRSF6) associated factor 1
FAM170B family with sequence similarity 170, member B
FAM20B family with sequence similarity 20, member B
FAM86B2 family with sequence similarity 86, member B2
FBXL4 F-box and leucine-rich repeat protein 4
FBXL7 F-box and leucine-rich repeat protein 7
FBXO30 F-box protein 30
FBXO5 F-box protein 5
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FH fumarate hydratase
FMR1NB fragile X mental retardation 1 neighbor
FNTA farnesyltransferase, CAAX box, alpha
FPGS folylpolyglutamate synthase
FRK fyn-related Src family tyrosine kinase
FTL ferritin, light polypeptide
GAMT guanidinoacetate N-methyltransferase
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GAS2L3 growth arrest-specific 2 like 3
GATSL2 GATS protein-like 2
GMPS guanine monphosphate synthase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GNPDA1 glucosamine-6-phosphate deaminase 1
GOLGA7 golgin A7
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPR26 G protein-coupled receptor 26
GRK6 G protein-coupled receptor kinase 6
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
GRPEL2 GrpE-like 2, mitochondrial (E. coli)
GSR glutathione reductase
GSTM4 glutathione S-transferase mu 4
GSTP1 glutathione S-transferase pi 1
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
GTPBP8 GTP-binding protein 8 (putative)
GUSBP1 glucuronidase, beta pseudogene 1
GYG1 glycogenin 1
H2AFZ H2A histone family, member Z
HACL1 2-hydroxyacyl-CoA lyase 1
HADH hydroxyacyl-CoA dehydrogenase
HAUS3 HAUS augmin-like complex, subunit 3
HBS1L HBS1-like translational GTPase
HCG4B HLA complex group 4B (non-protein coding)
HDAC2 histone deacetylase 2
HECA headcase homolog (Drosophila)
HMGN2 high mobility group nucleosomal binding domain 2
HMMR hyaluronan-mediated motility receptor (RHAMM)
HN1 hematological and neurological expressed 1
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12
HSF2 heat shock transcription factor 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA14 heat shock 70kDa protein 14
HSPA4L heat shock 70kDa protein 4-like
IARS isoleucyl-tRNA synthetase
IFNA8 interferon, alpha 8
IFRD1 interferon-related developmental regulator 1
IL17F interleukin 17F
IL7 interleukin 7
KANSL2 KAT8 regulatory NSL complex subunit 2
KATNA1 katanin p60 (ATPase containing) subunit A 1
KCNIP4 Kv channel interacting protein 4
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KGFLP1 fibroblast growth factor 7 pseudogene
KIAA0319 KIAA0319
KIAA0368 KIAA0368
KIAA1191 KIAA1191
KIAA1524 KIAA1524
KIF20A kinesin family member 20A
KLF11 Kruppel-like factor 11
KLHL21 kelch-like family member 21
KNSTRN kinetochore-localized astrin/SPAG5 binding protein
KPNA1 karyopherin alpha 1 (importin alpha 5)
KRT15 keratin 15, type I
KYNU kynureninase
LARP1B La ribonucleoprotein domain family, member 1B
LARP4 La ribonucleoprotein domain family, member 4
LARS leucyl-tRNA synthetase
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LOC285627 uncharacterized LOC285627
LOC388955 PRELI domain-containing protein 1, mitochondrial pseudogene
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LTV1 LTV1 ribosome biogenesis factor
LYAR Ly1 antibody reactive
LYPLAL1 lysophospholipase-like 1
MAOA monoamine oxidase A
MAP7 microtubule-associated protein 7
MAPK6 mitogen-activated protein kinase 6
MARS methionyl-tRNA synthetase
MAT2B methionine adenosyltransferase II, beta
MBP myelin basic protein
MCM9 minichromosome maintenance complex component 9
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MED27 mediator complex subunit 27
METAP1 methionyl aminopeptidase 1
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MINA MYC induced nuclear antigen
MKRN2 makorin ring finger protein 2
MLH1 mutL homolog 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
MPHOSPH9 M-phase phosphoprotein 9
MRFAP1 Morf4 family associated protein 1
MRPL18 mitochondrial ribosomal protein L18
MRPL22 mitochondrial ribosomal protein L22
MRPS30 mitochondrial ribosomal protein S30
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NAMPT nicotinamide phosphoribosyltransferase
NAP1L4 nucleosome assembly protein 1-like 4
NCAPG non-SMC condensin I complex, subunit G
NDC80 NDC80 kinetochore complex component
NDNL2 necdin-like 2
NDRG4 NDRG family member 4
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
NEFM neurofilament, medium polypeptide
NFE2L2 nuclear factor, erythroid 2-like 2
NGLY1 N-glycanase 1
NHP2 NHP2 ribonucleoprotein
NHSL1 NHS-like 1
NIT2 nitrilase family, member 2
NKAIN2 Na+/K+ transporting ATPase interacting 2
NOP14 NOP14 nucleolar protein
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NRD1 nardilysin (N-arginine dibasic convertase)
NSUN3 NOP2/Sun domain family, member 3
NSUN4 NOP2/Sun domain family, member 4
NT5DC1 5'-nucleotidase domain containing 1
NUDCD2 NudC domain containing 2
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14
NUP155 nucleoporin 155kDa
NUP205 nucleoporin 205kDa
NUP43 nucleoporin 43kDa
NUP98 nucleoporin 98kDa
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
NUSAP1 nucleolar and spindle associated protein 1
OLFM1 olfactomedin 1
OSGIN1 oxidative stress induced growth inhibitor 1
PAWR PRKC, apoptosis, WT1, regulator
PCCB propionyl CoA carboxylase, beta polypeptide
PCNA proliferating cell nuclear antigen
PCNP PEST proteolytic signal containing nuclear protein
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PEF1 penta-EF-hand domain containing 1
PEX3 peroxisomal biogenesis factor 3
PGD phosphogluconate dehydrogenase
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIR pirin (iron-binding nuclear protein)
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
POC5 POC5 centriolar protein
PPIF peptidylprolyl isomerase F
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRDX1 peroxiredoxin 1
PRDX6 peroxiredoxin 6
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2
PRR11 proline rich 11
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PTGR1 prostaglandin reductase 1
PTTG1 pituitary tumor-transforming 1
PTTG3P pituitary tumor-transforming 3, pseudogene
QSER1 glutamine and serine rich 1
RAB12 RAB12, member RAS oncogene family
RAB30 RAB30, member RAS oncogene family
RAB32 RAB32, member RAS oncogene family
RABL3 RAB, member of RAS oncogene family-like 3
RACGAP1 Rac GTPase activating protein 1
RARS arginyl-tRNA synthetase
RBBP7 retinoblastoma binding protein 7
REG1A regenerating islet-derived 1 alpha
REPS1 RALBP1 associated Eps domain containing 1
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RIT1 Ras-like without CAAX 1
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RNF217 ring finger protein 217
RNF4 ring finger protein 4
RNF5P1 ring finger protein 5, E3 ubiquitin protein ligase pseudogene 1
RNPEP arginyl aminopeptidase (aminopeptidase B)
RPF2 ribosome production factor 2 homolog (S. cerevisiae)
RPL24 ribosomal protein L24
RPL26L1 ribosomal protein L26-like 1
RRM1 ribonucleotide reductase M1
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
RTN3 reticulon 3
SAMD5 sterile alpha motif domain containing 5
SCAF8 SR-related CTD-associated factor 8
SCIN scinderin
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SENP8 SUMO/sentrin specific peptidase family member 8
SF3B5 splicing factor 3b, subunit 5, 10kDa
SFXN1 sideroflexin 1
SGOL1 shugoshin-like 1 (S. pombe)
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
SIMC1 SUMO-interacting motifs containing 1
SKP1 S-phase kinase-associated protein 1
SLBP stem-loop binding protein
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC25A38 solute carrier family 25, member 38
SLC25A40 solute carrier family 25, member 40
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMOC2 SPARC related modular calcium binding 2
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5)
SOD1 superoxide dismutase 1, soluble
SOST sclerostin
SPESP1 sperm equatorial segment protein 1
SPIN2B spindlin family, member 2B
SPP1 secreted phosphoprotein 1
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SQSTM1 sequestosome 1
SRPK1 SRSF protein kinase 1
SRXN1 sulfiredoxin 1
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3
STARD7 StAR-related lipid transfer (START) domain containing 7
STIP1 stress-induced phosphoprotein 1
STRAP serine/threonine kinase receptor associated protein
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
STX18 syntaxin 18
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TACC3 transforming, acidic coiled-coil containing protein 3
TALDO1 transaldolase 1
TARS threonyl-tRNA synthetase
TBC1D14 TBC1 domain family, member 14
TBC1D23 TBC1 domain family, member 23
TBCA tubulin folding cofactor A
TBP TATA box binding protein
TBPL1 TBP-like 1
TCP1 t-complex 1
TDP2 tyrosyl-DNA phosphodiesterase 2
TFG TRK-fused gene
TGDS TDP-glucose 4,6-dehydratase
THSD7A thrombospondin, type I, domain containing 7A
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TLK1 tousled-like kinase 1
TLR1 toll-like receptor 1
TMEM109 transmembrane protein 109
TMEM126A transmembrane protein 126A
TMEM132B transmembrane protein 132B
TMEM179 transmembrane protein 179
TMEM206 transmembrane protein 206
TMEM242 transmembrane protein 242
TMEM37 transmembrane protein 37
TMEM38B transmembrane protein 38B
TMX2 thioredoxin-related transmembrane protein 2
TNIP2 TNFAIP3 interacting protein 2
TNPO1 transportin 1
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TPD52L1 tumor protein D52-like 1
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae)
TSEN15 TSEN15 tRNA splicing endonuclease subunit
TSPAN17 tetraspanin 17
TSPYL1 TSPY-like 1
TTC1 tetratricopeptide repeat domain 1
TTC22 tetratricopeptide repeat domain 22
TTC4 tetratricopeptide repeat domain 4
TUBE1 tubulin, epsilon 1
TXLNG taxilin gamma
TXN thioredoxin
TXNL1 thioredoxin-like 1
TXNRD1 thioredoxin reductase 1
UBE2A ubiquitin-conjugating enzyme E2A
UBE2S ubiquitin-conjugating enzyme E2S
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UQCRC1 ubiquinol-cytochrome c reductase core protein I
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP33 ubiquitin specific peptidase 33
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
UST uronyl-2-sulfotransferase
VDAC2 voltage-dependent anion channel 2
VDAC3 voltage-dependent anion channel 3
VTA1 vesicle (multivesicular body) trafficking 1
WASF2 WAS protein family, member 2
WDR66 WD repeat domain 66
WSB2 WD repeat and SOCS box containing 2
WTAP Wilms tumor 1 associated protein
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZBTB11 zinc finger and BTB domain containing 11
ZDHHC18 zinc finger, DHHC-type containing 18
ZUFSP zinc finger with UFM1-specific peptidase domain
ZZZ3 zinc finger, ZZ-type containing 3

low expression

Symbol Name
SBF2 SET binding factor 2