Lung squamous cell carcinoma_LUSC_TCGA-63-7021-01A-11R-1949-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

426 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-63-7021-01A-11R-1949-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A2ML1 alpha-2-macroglobulin-like 1
AACS acetoacetyl-CoA synthetase
ABHD17C abhydrolase domain containing 17C
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACER1 alkaline ceramidase 1
ACSL1 acyl-CoA synthetase long-chain family member 1
ADCY5 adenylate cyclase 5
ADRBK2 adrenergic, beta, receptor kinase 2
AEN apoptosis enhancing nuclease
AGO2 argonaute RISC catalytic component 2
AHNAK2 AHNAK nucleoprotein 2
AIM1L absent in melanoma 1-like
AKR7A2P1 aldo-keto reductase family 7, member A2 pseudogene 1
ALOXE3 arachidonate lipoxygenase 3
AMTN amelotin
ANKHD1 ankyrin repeat and KH domain containing 1
ANKRD37 ankyrin repeat domain 37
ANP32C acidic (leucine-rich) nuclear phosphoprotein 32 family, member C
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
ANXA1 annexin A1
ANXA2P1 annexin A2 pseudogene 1
ANXA2P3 annexin A2 pseudogene 3
ANXA8L1 annexin A8-like 1
ARHGAP26 Rho GTPase activating protein 26
ARHGAP27 Rho GTPase activating protein 27
ARHGAP32 Rho GTPase activating protein 32
ARHGEF35 Rho guanine nucleotide exchange factor (GEF) 35
ARMS2 age-related maculopathy susceptibility 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASPG asparaginase
ATG4D autophagy related 4D, cysteine peptidase
ATP5L2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
BAG3 BCL2-associated athanogene 3
BCL2L2 BCL2-like 2
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BDKRB2 bradykinin receptor B2
BHLHE40 basic helix-loop-helix family, member e40
BICD2 bicaudal D homolog 2 (Drosophila)
BNC1 basonuclin 1
C10ORF76 chromosome 10 open reading frame 76
C10ORF99 chromosome 10 open reading frame 99
C11ORF42 chromosome 11 open reading frame 42
C20ORF166-AS1 C20orf166 antisense RNA 1
C4ORF50 chromosome 4 open reading frame 50
C4ORF51 chromosome 4 open reading frame 51
C9ORF3 chromosome 9 open reading frame 3
CABS1 calcium-binding protein, spermatid-specific 1
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CALML3 calmodulin-like 3
CALML5 calmodulin-like 5
CARD14 caspase recruitment domain family, member 14
CASZ1 castor zinc finger 1
CCDC85C coiled-coil domain containing 85C
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDHR1 cadherin-related family member 1
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN2AIP CDKN2A interacting protein
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDRT15 CMT1A duplicated region transcript 15
CDYL2 chromodomain protein, Y-like 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM19 carcinoembryonic antigen-related cell adhesion molecule 19
CENPC centromere protein C
CENPP centromere protein P
CEP164 centrosomal protein 164kDa
CERS3 ceramide synthase 3
CIART circadian associated repressor of transcription
CLCN3 chloride channel, voltage-sensitive 3
CLK2P1 CDC-like kinase 2, pseudogene 1
CMIP c-Maf inducing protein
CNFN cornifelin
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COPZ2 coatomer protein complex, subunit zeta 2
CPA6 carboxypeptidase A6
CRHBP corticotropin releasing hormone binding protein
CRHR1-IT1 CRHR1 intronic transcript 1
CRYAB crystallin, alpha B
CRYGS crystallin, gamma S
CSNK1A1L casein kinase 1, alpha 1-like
CSNK1G2-AS1 CSNK1G2 antisense RNA 1
CTTNBP2 cortactin binding protein 2
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
CYCSP52 cytochrome c, somatic pseudogene 52
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCTD dCMP deaminase
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DMP1 dentin matrix acidic phosphoprotein 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DOC2B double C2-like domains, beta
DSC2 desmocollin 2
DSG3 desmoglein 3
DSG4 desmoglein 4
DUOXA1 dual oxidase maturation factor 1
DUSP14 dual specificity phosphatase 14
DYNLT3 dynein, light chain, Tctex-type 3
EDA ectodysplasin A
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EIF3IP1 eukaryotic translation initiation factor 3, subunit I pseudogene 1
EPHA1 EPH receptor A1
EPHB1 EPH receptor B1
EPPK1 epiplakin 1
ERICH5 glutamate-rich 5
ETFDH electron-transferring-flavoprotein dehydrogenase
ETV3 ets variant 3
EVPL envoplakin
EXOC8 exocyst complex component 8
FAM129A family with sequence similarity 129, member A
FAM129B family with sequence similarity 129, member B
FAM135A family with sequence similarity 135, member A
FAM157A family with sequence similarity 157, member A
FAM160A1 family with sequence similarity 160, member A1
FAM43A family with sequence similarity 43, member A
FAM58BP cyclin-related protein FAM58B
FAM71F1 family with sequence similarity 71, member F1
FAM71F2 family with sequence similarity 71, member F2
FAM83H family with sequence similarity 83, member H
FAM89A family with sequence similarity 89, member A
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FDPSP2 farnesyl diphosphate synthase pseudogene 2
FEM1C fem-1 homolog c (C. elegans)
FER1L6 fer-1-like family member 6
FETUB fetuin B
FLJ33360 FLJ33360 protein
FLJ42393 uncharacterized LOC401105
FLJ44635 TPT1-like protein
FLRT2 fibronectin leucine rich transmembrane protein 2
FOSL1 FOS-like antigen 1
FOXD4L6 forkhead box D4-like 6
FOXP2 forkhead box P2
FRYL FRY-like
FURIN furin (paired basic amino acid cleaving enzyme)
FUT2 fucosyltransferase 2 (secretor status included)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAS8 growth arrest-specific 8
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GON4L gon-4-like (C. elegans)
GPRIN1 G protein regulated inducer of neurite outgrowth 1
GRHL3 grainyhead-like 3 (Drosophila)
GRXCR2 glutaredoxin, cysteine rich 2
GSDMC gasdermin C
HAS3 hyaluronan synthase 3
HBEGF heparin-binding EGF-like growth factor
HCAR2 hydroxycarboxylic acid receptor 2
HDAC1 histone deacetylase 1
HEPHL1 hephaestin-like 1
HIGD2B HIG1 hypoxia inducible domain family, member 2B
HMOX2 heme oxygenase 2
HOXC13 homeobox C13
HRG histidine-rich glycoprotein
HSP90B3P heat shock protein 90kDa beta (Grp94), member 3, pseudogene
HSPA4L heat shock 70kDa protein 4-like
HYPM huntingtin interacting protein M
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IFFO2 intermediate filament family orphan 2
IGBP1P1 immunoglobulin (CD79A) binding protein 1 pseudogene 1
IGLL1 immunoglobulin lambda-like polypeptide 1
IL1RN interleukin 1 receptor antagonist
IL22RA1 interleukin 22 receptor, alpha 1
IL31RA interleukin 31 receptor A
IL36A interleukin 36, alpha
ING2 inhibitor of growth family, member 2
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IQCG IQ motif containing G
IRF5 interferon regulatory factor 5
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein
IVL involucrin
JMJD7-PLA2G4B JMJD7-PLA2G4B readthrough
JMY junction mediating and regulatory protein, p53 cofactor
JUP junction plakoglobin
KANK1 KN motif and ankyrin repeat domains 1
KAZN kazrin, periplakin interacting protein
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCTD5 potassium channel tetramerization domain containing 5
KIAA0226 KIAA0226
KIF11 kinesin family member 11
KIFC2 kinesin family member C2
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KLF4 Kruppel-like factor 4 (gut)
KLHL21 kelch-like family member 21
KLK10 kallikrein-related peptidase 10
KLK13 kallikrein-related peptidase 13
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT6C keratin 6C, type II
KRT80 keratin 80, type II
LAD1 ladinin 1
LALBA lactalbumin, alpha-
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial)
LCE1B late cornified envelope 1B
LCE1C late cornified envelope 1C
LCE1F late cornified envelope 1F
LDB1 LIM domain binding 1
LIM2 lens intrinsic membrane protein 2, 19kDa
LINS lines homolog (Drosophila)
LIPH lipase, member H
LOC100130331 POTE ankyrin domain family, member F pseudogene
LOC100133331 uncharacterized LOC100133331
LOC154761 family with sequence similarity 115, member C pseudogene
LOC344967 acyl-CoA thioesterase 7 pseudogene
LOC407835 mitogen-activated protein kinase kinase 2 pseudogene
LOC649330
LOC652276 potassium channel tetramerization domain containing 5 pseudogene
LOX lysyl oxidase
LRIT2 leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
LRRC14 leucine rich repeat containing 14
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LRRC8E leucine rich repeat containing 8 family, member E
LTB4R leukotriene B4 receptor
LTB4R2 leukotriene B4 receptor 2
LY6G6C lymphocyte antigen 6 complex, locus G6C
LYNX1 Ly6/neurotoxin 1
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene)
MAML3 mastermind-like 3 (Drosophila)
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKBP1 mitogen-activated protein kinase binding protein 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MAST4 microtubule associated serine/threonine kinase family member 4
MFSD6L major facilitator superfamily domain containing 6-like
MGLL monoglyceride lipase
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type
MREG melanoregulin
MROH1 maestro heat-like repeat family member 1
MROH6 maestro heat-like repeat family member 6
MROH7 maestro heat-like repeat family member 7
MRS2P2 MRS2 pseudogene 2
MXD1 MAX dimerization protein 1
MYO1E myosin IE
MYO1H myosin IH
NACA2 nascent polypeptide-associated complex alpha subunit 2
NBEAL2 neurobeachin-like 2
NCR2 natural cytotoxicity triggering receptor 2
NEUROG1 neurogenin 1
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NIPAL4 NIPA-like domain containing 4
NLRX1 NLR family member X1
NME2P1 NME/NM23 nucleoside diphosphate kinase 2 pseudogene 1
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
NR1D1 nuclear receptor subfamily 1, group D, member 1
NRBP2 nuclear receptor binding protein 2
NUAK2 NUAK family, SNF1-like kinase, 2
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
OASL 2'-5'-oligoadenylate synthetase-like
OCIAD1 OCIA domain containing 1
OCIAD2 OCIA domain containing 2
OCLM oculomedin
OPN4 opsin 4
OR52I1 olfactory receptor, family 52, subfamily I, member 1
OR5D14 olfactory receptor, family 5, subfamily D, member 14
OTUD7A OTU deubiquitinase 7A
OVGP1 oviductal glycoprotein 1, 120kDa
OVOL1 ovo-like zinc finger 1
PA2G4P4 proliferation-associated 2G4 pseudogene 4
PACS1 phosphofurin acidic cluster sorting protein 1
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PC pyruvate carboxylase
PCDHGA10 protocadherin gamma subfamily A, 10
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDLIM5 PDZ and LIM domain 5
PERM1 PPARGC1 and ESRR induced regulator, muscle 1
PGLYRP3 peptidoglycan recognition protein 3
PI3 peptidase inhibitor 3, skin-derived
PIAS3 protein inhibitor of activated STAT, 3
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PIP5K1P1 phosphatidylinositol-4-phosphate 5-kinase, type I, pseudogene 1
PIPSL PIP5K1A and PSMD4-like, pseudogene
PITX1 paired-like homeodomain 1
PKP1 plakophilin 1
PLA2G3 phospholipase A2, group III
PLEC plectin
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PMVK phosphomevalonate kinase
POM121L1P POM121 transmembrane nucleoporin-like 1, pseudogene
POTEE POTE ankyrin domain family, member E
POTEM POTE ankyrin domain family, member M
POU5F2 POU domain class 5, transcription factor 2
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPL periplakin
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRAMEF8 PRAME family member 8
PRDM1 PR domain containing 1, with ZNF domain
PRINS psoriasis associated non-protein coding RNA induced by stress
PRO0611 PRO0611 protein
PROX2 prospero homeobox 2
PRSS27 protease, serine 27
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PTTG2 pituitary tumor-transforming 2
PVRL4 poliovirus receptor-related 4
QRFPR pyroglutamylated RFamide peptide receptor
QRICH2 glutamine rich 2
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RAET1K retinoic acid early transcript 1K pseudogene
RAET1L retinoic acid early transcript 1L
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RBM33 RNA binding motif protein 33
RGS14 regulator of G-protein signaling 14
RGSL1 regulator of G-protein signaling like 1
RHCG Rh family, C glycoprotein
RIMS3 regulating synaptic membrane exocytosis 3
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RPL19P12 ribosomal protein L19 pseudogene 12
RPL21P44 ribosomal protein L21 pseudogene 44
RPL31P11 ribosomal protein L31 pseudogene 11
S100A8 S100 calcium binding protein A8
SAG S-antigen; retina and pineal gland (arrestin)
SBF1P1 SET binding factor 1 pseudogene 1
SBSN suprabasin
SCAMP2 secretory carrier membrane protein 2
SCAPER S-phase cyclin A-associated protein in the ER
SCO2 SCO2 cytochrome c oxidase assembly protein
SCRIB scribbled planar cell polarity protein
SDC4P syndecan 4 pseudogene
SDCBP2 syndecan binding protein (syntenin) 2
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7
SFN stratifin
SH3PXD2A SH3 and PX domains 2A
SH3RF2 SH3 domain containing ring finger 2
SLAIN2 SLAIN motif family, member 2
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC10A7 solute carrier family 10, member 7
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A20 solute carrier family 22, member 20
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
SLC45A4 solute carrier family 45, member 4
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLURP1 secreted LY6/PLAUR domain containing 1
SMAD3 SMAD family member 3
SPANXN3 SPANX family, member N3
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPRR2A small proline-rich protein 2A
SPRR2B small proline-rich protein 2B
SPRR2C small proline-rich protein 2C (pseudogene)
SPRR2D small proline-rich protein 2D
SPRR2E small proline-rich protein 2E
SPRR2F small proline-rich protein 2F
SPRR2G small proline-rich protein 2G
SPRR3 small proline-rich protein 3
SPRR4 small proline-rich protein 4
ST7L suppression of tumorigenicity 7 like
STARD5 StAR-related lipid transfer (START) domain containing 5
STK32B serine/threonine kinase 32B
STOX2 storkhead box 2
STPG1 sperm-tail PG-rich repeat containing 1
STXBP5 syntaxin binding protein 5 (tomosyn)
SUSD4 sushi domain containing 4
SYCP1 synaptonemal complex protein 1
SYCP3 synaptonemal complex protein 3
SYNM synemin, intermediate filament protein
TACC2 transforming, acidic coiled-coil containing protein 2
TAS2R50 taste receptor, type 2, member 50
TAS2R60 taste receptor, type 2, member 60
TBC1D3P2 TBC1 domain family, member 3 pseudogene 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TCAF2 TRPM8 channel-associated factor 2
TCHH trichohyalin
TEC tec protein tyrosine kinase
TGM1 transglutaminase 1
TGM3 transglutaminase 3
TGM5 transglutaminase 5
TGM6 transglutaminase 6
TGM7 transglutaminase 7
TICAM1 toll-like receptor adaptor molecule 1
TLN2 talin 2
TMEM154 transmembrane protein 154
TMEM159 transmembrane protein 159
TMEM54 transmembrane protein 54
TMEM79 transmembrane protein 79
TMPRSS11A transmembrane protease, serine 11A
TMPRSS11B transmembrane protease, serine 11B
TMPRSS11BNL TMPRSS11B N-terminal like, pseudogene
TMPRSS11D transmembrane protease, serine 11D
TMPRSS11F transmembrane protease, serine 11F
TMPRSS13 transmembrane protease, serine 13
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNIP3 TNFAIP3 interacting protein 3
TP53INP2 tumor protein p53 inducible nuclear protein 2
TPI1P3 triosephosphate isomerase 1 pseudogene 3
TPPP2 tubulin polymerization-promoting protein family member 2
TRAF3IP2 TRAF3 interacting protein 2
TRIM29 tripartite motif containing 29
TRIM7 tripartite motif containing 7
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TSHZ2 teashirt zinc finger homeobox 2
TSPAN10 tetraspanin 10
TTLL13P tubulin tyrosine ligase-like family member 13, pseudogene
TTTY10 testis-specific transcript, Y-linked 10 (non-protein coding)
TUBA4A tubulin, alpha 4a
TXK TXK tyrosine kinase
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
ULBP1 UL16 binding protein 1
ULBP2 UL16 binding protein 2
VPS9D1 VPS9 domain containing 1
VSIG8 V-set and immunoglobulin domain containing 8
WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules
WNT2B wingless-type MMTV integration site family, member 2B
WNT7B wingless-type MMTV integration site family, member 7B
XCR1 chemokine (C motif) receptor 1
XK X-linked Kx blood group
YIPF7 Yip1 domain family, member 7
YOD1 YOD1 deubiquitinase
ZBTB7A zinc finger and BTB domain containing 7A
ZBTB7B zinc finger and BTB domain containing 7B
ZC3H12A zinc finger CCCH-type containing 12A
ZC3H12C zinc finger CCCH-type containing 12C
ZC3H3 zinc finger CCCH-type containing 3
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZNF185 zinc finger protein 185 (LIM domain)
ZNF276 zinc finger protein 276
ZNF330 zinc finger protein 330
ZNF750 zinc finger protein 750
ZNF827 zinc finger protein 827