Lung squamous cell carcinoma_LUSC_TCGA-60-2712-01A-01R-0851-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

373 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-60-2712-01A-01R-0851-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACSM1 acyl-CoA synthetase medium-chain family member 1
ADAM28 ADAM metallopeptidase domain 28
ADAM6 ADAM metallopeptidase domain 6 (pseudogene)
ADAMDEC1 ADAM-like, decysin 1
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional)
AK3 adenylate kinase 3
ALX3 ALX homeobox 3
ANKHD1 ankyrin repeat and KH domain containing 1
ANKRD55 ankyrin repeat domain 55
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ARPP21 cAMP-regulated phosphoprotein, 21kDa
ARSD arylsulfatase D
ASMTL acetylserotonin O-methyltransferase-like
BBX bobby sox homolog (Drosophila)
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BEST3 bestrophin 3
BHLHA15 basic helix-loop-helix family, member a15
BTF3 basic transcription factor 3
BTG1 B-cell translocation gene 1, anti-proliferative
BTNL2 butyrophilin-like 2
C10ORF55 chromosome 10 open reading frame 55
C12ORF74 chromosome 12 open reading frame 74
C1ORF101 chromosome 1 open reading frame 101
C1ORF204 chromosome 1 open reading frame 204
C1ORF95 chromosome 1 open reading frame 95
C1QL3 complement component 1, q subcomponent-like 3
C3ORF17 chromosome 3 open reading frame 17
C4ORF50 chromosome 4 open reading frame 50
C6ORF222 chromosome 6 open reading frame 222
C9ORF9 chromosome 9 open reading frame 9
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCDC112 coiled-coil domain containing 112
CCDC115 coiled-coil domain containing 115
CCDC27 coiled-coil domain containing 27
CCDC60 coiled-coil domain containing 60
CCDC7 coiled-coil domain containing 7
CCL11 chemokine (C-C motif) ligand 11
CCR2 chemokine (C-C motif) receptor 2
CCR4 chemokine (C-C motif) receptor 4
CD27 CD27 molecule
CD38 CD38 molecule
CD5 CD5 molecule
CD6 CD6 molecule
CD70 CD70 molecule
CDC42SE2 CDC42 small effector 2
CDH22 cadherin 22, type 2
CDIP1 cell death-inducing p53 target 1
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN2AIPNL CDKN2A interacting protein N-terminal like
CEP128 centrosomal protein 128kDa
CEP68 centrosomal protein 68kDa
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHODL-AS1 CHODL antisense RNA 1
CLEC10A C-type lectin domain family 10, member A
CLK4 CDC-like kinase 4
CLLU1 chronic lymphocytic leukemia up-regulated 1
CLLU1OS chronic lymphocytic leukemia up-regulated 1 opposite strand
CLSTN2 calsyntenin 2
CLUL1 clusterin-like 1 (retinal)
COL23A1 collagen, type XXIII, alpha 1
COLCA1 colorectal cancer associated 1
COLCA2 colorectal cancer associated 2
COX6B2 cytochrome c oxidase subunit VIb polypeptide 2 (testis)
CPNE5 copine V
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CXCL14 chemokine (C-X-C motif) ligand 14
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
CYP4X1 cytochrome P450, family 4, subfamily X, polypeptide 1
CYTIP cytohesin 1 interacting protein
DCP2 decapping mRNA 2
DERL3 derlin 3
DGKZ diacylglycerol kinase, zeta
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DNPEP aspartyl aminopeptidase
DOCK10 dedicator of cytokinesis 10
EBF2 early B-cell factor 2
EEA1 early endosome antigen 1
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EEF1A1P9 eukaryotic translation elongation factor 1 alpha 1 pseudogene 9
EEF1G eukaryotic translation elongation factor 1 gamma
EEF2 eukaryotic translation elongation factor 2
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3L eukaryotic translation initiation factor 3, subunit L
EIF4B eukaryotic translation initiation factor 4B
EOMES eomesodermin
EPB41L4A-AS1 EPB41L4A antisense RNA 1
EPS15 epidermal growth factor receptor pathway substrate 15
ERAP2 endoplasmic reticulum aminopeptidase 2
FABP7 fatty acid binding protein 7, brain
FAM117A family with sequence similarity 117, member A
FAM170A family with sequence similarity 170, member A
FAM222A family with sequence similarity 222, member A
FAM43A family with sequence similarity 43, member A
FAM46C family with sequence similarity 46, member C
FAM53C family with sequence similarity 53, member C
FAM71E2 family with sequence similarity 71, member E2
FBXO31 F-box protein 31
FBXW11 F-box and WD repeat domain containing 11
FCRL5 Fc receptor-like 5
FKBP11 FK506 binding protein 11, 19 kDa
FKBP5 FK506 binding protein 5
FLJ41941 uncharacterized LOC100192420
FOXK1 forkhead box K1
FRMD4A FERM domain containing 4A
GAB2 GRB2-associated binding protein 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GH1 growth hormone 1
GJD3 gap junction protein, delta 3, 31.9kDa
GLCCI1 glucocorticoid induced 1
GLTSCR2 glioma tumor suppressor candidate region gene 2
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPR156 G protein-coupled receptor 156
GPR31 G protein-coupled receptor 31
GPRC5B G protein-coupled receptor, class C, group 5, member B
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GRK6 G protein-coupled receptor kinase 6
GRM4 glutamate receptor, metabotropic 4
GZMK granzyme K (granzyme 3; tryptase II)
HACD2 3-hydroxyacyl-CoA dehydratase 2
HCK HCK proto-oncogene, Src family tyrosine kinase
HCLS1 hematopoietic cell-specific Lyn substrate 1
HDAC3 histone deacetylase 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-G major histocompatibility complex, class I, G
HOTAIR HOX transcript antisense RNA
HOXC10 homeobox C10
HOXC5 homeobox C5
HOXC6 homeobox C6
HOXC9 homeobox C9
HRH2 histamine receptor H2
HRSP12 heat-responsive protein 12
HS6ST3 heparan sulfate 6-O-sulfotransferase 3
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
ICAM3 intercellular adhesion molecule 3
IGBP1 immunoglobulin (CD79A) binding protein 1
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10RA interleukin 10 receptor, alpha
IL12RB2 interleukin 12 receptor, beta 2
IL23A interleukin 23, alpha subunit p19
IL26 interleukin 26
IL32 interleukin 32
IMP4 IMP4, U3 small nucleolar ribonucleoprotein
IMPAD1 inositol monophosphatase domain containing 1
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
ING4 inhibitor of growth family, member 4
INSL3 insulin-like 3 (Leydig cell)
IRAK3 interleukin-1 receptor-associated kinase 3
IRF4 interferon regulatory factor 4
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein
JADE2 jade family PHD finger 2
JAK1 Janus kinase 1
JAK3 Janus kinase 3
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KCTD19 potassium channel tetramerization domain containing 19
KDM3B lysine (K)-specific demethylase 3B
KDSR 3-ketodihydrosphingosine reductase
KIAA0141 KIAA0141
KIAA1217 KIAA1217
KIAA1407 KIAA1407
KLLN killin, p53-regulated DNA replication inhibitor
KRT31 keratin 31, type I
KRT34 keratin 34, type I
KRT35 keratin 35, type I
KRTAP12-3 keratin associated protein 12-3
KRTAP4-12 keratin associated protein 4-12
KY kyphoscoliosis peptidase
LARS leucyl-tRNA synthetase
LAX1 lymphocyte transmembrane adaptor 1
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LETMD1 LETM1 domain containing 1
LINC00114 long intergenic non-protein coding RNA 114
LOC100240735 uncharacterized LOC100240735
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC441666 zinc finger protein 91 pseudogene
LOC650293 seven transmembrane helix receptor
LPIN1 lipin 1
LYRM7 LYR motif containing 7
LZTS1 leucine zipper, putative tumor suppressor 1
MAML1 mastermind-like 1 (Drosophila)
MAT2B methionine adenosyltransferase II, beta
MBD4 methyl-CpG binding domain protein 4
MBNL1 muscleblind-like splicing regulator 1
MED13L mediator complex subunit 13-like
MEGF10 multiple EGF-like-domains 10
MEGF6 multiple EGF-like-domains 6
MEI1 meiosis inhibitor 1
MRPS27 mitochondrial ribosomal protein S27
MTNR1A melatonin receptor 1A
MYB v-myb avian myeloblastosis viral oncogene homolog
MYLK4 myosin light chain kinase family, member 4
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1
NACA nascent polypeptide-associated complex alpha subunit
NAP1L1 nucleosome assembly protein 1-like 1
NARFL nuclear prelamin A recognition factor-like
NBPF14 neuroblastoma breakpoint family, member 14
NCF1B neutrophil cytosolic factor 1B pseudogene
NDN necdin, melanoma antigen (MAGE) family member
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEU3 sialidase 3 (membrane sialidase)
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NHEJ1 nonhomologous end-joining factor 1
NMNAT3 nicotinamide nucleotide adenylyltransferase 3
NPVF neuropeptide VF precursor
NREP neuronal regeneration related protein
NUTM2A NUT family member 2A
NXPH1 neurexophilin 1
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OPTN optineurin
OR14A16 olfactory receptor, family 14, subfamily A, member 16
OR2AE1 olfactory receptor, family 2, subfamily AE, member 1
OR2C1 olfactory receptor, family 2, subfamily C, member 1
OR2L13 olfactory receptor, family 2, subfamily L, member 13
OR2L1P olfactory receptor, family 2, subfamily L, member 1 pseudogene
OR2L3 olfactory receptor, family 2, subfamily L, member 3
OR2W3 olfactory receptor, family 2, subfamily W, member 3
OR52H1 olfactory receptor, family 52, subfamily H, member 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
P2RY8 purinergic receptor P2Y, G-protein coupled, 8
PABPC1 poly(A) binding protein, cytoplasmic 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PAX8 paired box 8
PCDHGB2 protocadherin gamma subfamily B, 2
PDDC1 Parkinson disease 7 domain containing 1
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIRT phosphoinositide-interacting regulator of transient receptor potential channels
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PLA2G2D phospholipase A2, group IID
PLAG1 pleiomorphic adenoma gene 1
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7
POU2AF1 POU class 2 associating factor 1
POU2F3 POU class 2 homeobox 3
POU4F1 POU class 4 homeobox 1
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRAMEF22 PRAME family member 22
PRDM1 PR domain containing 1, with ZNF domain
PRMT7 protein arginine methyltransferase 7
PRTG protogenin
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTEN phosphatase and tensin homolog
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPRVP protein tyrosine phosphatase, receptor type, V, pseudogene
QARS glutaminyl-tRNA synthetase
R3HDM2 R3H domain containing 2
RAB30 RAB30, member RAS oncogene family
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RASSF6 Ras association (RalGDS/AF-6) domain family member 6
RBMX RNA binding motif protein, X-linked
REEP5 receptor accessory protein 5
RELT RELT tumor necrosis factor receptor
RFPL4A ret finger protein-like 4A
RGAG4 retrotransposon gag domain containing 4
RNASEH2B ribonuclease H2, subunit B
RNF144B ring finger protein 144B
RNF152 ring finger protein 152
RNF165 ring finger protein 165
RNF44 ring finger protein 44
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL10A ribosomal protein L10a
RPL13 ribosomal protein L13
RPL13A ribosomal protein L13a
RPL17 ribosomal protein L17
RPL18A ribosomal protein L18a
RPL3 ribosomal protein L3
RPS2 ribosomal protein S2
RPS20 ribosomal protein S20
RPS4X ribosomal protein S4, X-linked
RSRC1 arginine/serine-rich coiled-coil 1
S100A7A S100 calcium binding protein A7A
SEC24A SEC24 family member A
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEPT6 septin 6
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SESN1 sestrin 1
SFMBT2 Scm-like with four mbt domains 2
SIGLEC10 sialic acid binding Ig-like lectin 10
SIMC1 SUMO-interacting motifs containing 1
SLAMF1 signaling lymphocytic activation molecule family member 1
SLAMF6 SLAM family member 6
SLAMF7 SLAM family member 7
SLAMF8 SLAM family member 8
SLC25A27 solute carrier family 25, member 27
SLC25A46 solute carrier family 25, member 46
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SLC41A3 solute carrier family 41, member 3
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
SLU7 SLU7 splicing factor homolog (S. cerevisiae)
SMAP2 small ArfGAP2
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SNHG4 small nucleolar RNA host gene 4
SP6 Sp6 transcription factor
SPIC Spi-C transcription factor (Spi-1/PU.1 related)
SSR4 signal sequence receptor, delta
ST18 suppression of tumorigenicity 18, zinc finger
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STEAP3 STEAP family member 3, metalloreductase
SYNE3 spectrin repeat containing, nuclear envelope family member 3
TAGAP T-cell activation RhoGTPase activating protein
TAPBP TAP binding protein (tapasin)
TAS1R3 taste receptor, type 1, member 3
TCF25 transcription factor 25 (basic helix-loop-helix)
TGFB2 transforming growth factor, beta 2
THEMIS2 thymocyte selection associated family member 2
TMEM131 transmembrane protein 131
TMEM143 transmembrane protein 143
TMEM171 transmembrane protein 171
TMEM19 transmembrane protein 19
TMEM30C transmembrane protein 30C
TMEM51-AS1 TMEM51 antisense RNA 1
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNIP1 TNFAIP3 interacting protein 1
TOB1 transducer of ERBB2, 1
TOX thymocyte selection-associated high mobility group box
TP53INP1 tumor protein p53 inducible nuclear protein 1
TRAPPC2 trafficking protein particle complex 2
TRIM35 tripartite motif containing 35
TRIM58 tripartite motif containing 58
TRPS1 trichorhinophalangeal syndrome I
TSC22D3 TSC22 domain family, member 3
TSKS testis-specific serine kinase substrate
TSPAN17 tetraspanin 17
TXLNB taxilin beta
TXNDC11 thioredoxin domain containing 11
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
UBE2B ubiquitin-conjugating enzyme E2B
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UBL4B ubiquitin-like 4B
UMODL1 uromodulin-like 1
UQCRC2 ubiquinol-cytochrome c reductase core protein II
VAV1 vav 1 guanine nucleotide exchange factor
VDAC1 voltage-dependent anion channel 1
WBP2NL WBP2 N-terminal like
WDR49 WD repeat domain 49
WDR64 WD repeat domain 64
WIPF1 WAS/WASL interacting protein family, member 1
WNT10B wingless-type MMTV integration site family, member 10B
WSCD2 WSC domain containing 2
WWOX WW domain containing oxidoreductase
XBP1 X-box binding protein 1
XCR1 chemokine (C motif) receptor 1
XRN1 5'-3' exoribonuclease 1
ZBP1 Z-DNA binding protein 1
ZC3H12D zinc finger CCCH-type containing 12D
ZFP36L2 ZFP36 ring finger protein-like 2
ZFPM2 zinc finger protein, FOG family member 2
ZIC2 Zic family member 2
ZNF33B zinc finger protein 33B