Lung squamous cell carcinoma_LUSC_TCGA-60-2710-01A-01R-0851-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

315 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-60-2710-01A-01R-0851-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACPP acid phosphatase, prostate
ADAL adenosine deaminase-like
ADCY3 adenylate cyclase 3
ADGRB2 adhesion G protein-coupled receptor B2
ALAD aminolevulinate dehydratase
AMIGO1 adhesion molecule with Ig-like domain 1
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
ARHGAP10 Rho GTPase activating protein 10
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARID5B AT rich interactive domain 5B (MRF1-like)
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
B3GALT5-AS1 B3GALT5 antisense RNA 1
BARD1 BRCA1 associated RING domain 1
BICD2 bicaudal D homolog 2 (Drosophila)
BRD3 bromodomain containing 3
BSDC1 BSD domain containing 1
C9ORF114 chromosome 9 open reading frame 114
C9ORF129 chromosome 9 open reading frame 129
CALML4 calmodulin-like 4
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CASZ1 castor zinc finger 1
CDC14C cell division cycle 14C
CDK9 cyclin-dependent kinase 9
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEP78 centrosomal protein 78kDa
CEP85 centrosomal protein 85kDa
CEP97 centrosomal protein 97kDa
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CIT citron rho-interacting serine/threonine kinase
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSTN1 calsyntenin 1
CORO2A coronin, actin binding protein, 2A
CRTC3 CREB regulated transcription coactivator 3
CRYGB crystallin, gamma B
CSNK1G1 casein kinase 1, gamma 1
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CTTNBP2 cortactin binding protein 2
CTTNBP2NL CTTNBP2 N-terminal like
CXORF51A chromosome X open reading frame 51A
CYFIP1 cytoplasmic FMR1 interacting protein 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAB2IP DAB2 interacting protein
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
DEFB106A defensin, beta 106A
DENND1A DENN/MADD domain containing 1A
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DIS3L DIS3 like exosome 3'-5' exoribonuclease
DLG5 discs, large homolog 5 (Drosophila)
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DPP8 dipeptidyl-peptidase 8
DST dystonin
E2F2 E2F transcription factor 2
E2F7 E2F transcription factor 7
ECE1 endothelin converting enzyme 1
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific
EFTUD1 elongation factor Tu GTP binding domain containing 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EMILIN3 elastin microfibril interfacer 3
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPHB6 EPH receptor B6
EPPK1 epiplakin 1
ERCC6L2 excision repair cross-complementation group 6-like 2
ETV4 ets variant 4
ETV5 ets variant 5
EXOC6B exocyst complex component 6B
FAM102A family with sequence similarity 102, member A
FAM111B family with sequence similarity 111, member B
FAM120A family with sequence similarity 120A
FAM120AOS family with sequence similarity 120A opposite strand
FAM129B family with sequence similarity 129, member B
FAM19A4 family with sequence similarity 19 (chemokine (C-C motif)-like), member A4
FAM212B family with sequence similarity 212, member B
FAM83H family with sequence similarity 83, member H
FANCC Fanconi anemia, complementation group C
FANCI Fanconi anemia, complementation group I
FETUB fetuin B
FGFR2 fibroblast growth factor receptor 2
FOXE1 forkhead box E1
FOXO3 forkhead box O3
FOXO3B forkhead box O3B pseudogene
FPGS folylpolyglutamate synthase
FSTL4 follistatin-like 4
GAPVD1 GTPase activating protein and VPS9 domains 1
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GGACT gamma-glutamylamine cyclotransferase
GLE1 GLE1 RNA export mediator
GMPS guanine monphosphate synthase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNB5 guanine nucleotide binding protein (G protein), beta 5
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR107 G protein-coupled receptor 107
GPR89B G protein-coupled receptor 89B
GPRC5D G protein-coupled receptor, class C, group 5, member D
GSK3B glycogen synthase kinase 3 beta
GSTM1 glutathione S-transferase mu 1
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HAUS2 HAUS augmin-like complex, subunit 2
HCFC1 host cell factor C1
HIATL1 hippocampus abundant transcript-like 1
HIPK1 homeodomain interacting protein kinase 1
HLF hepatic leukemia factor
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5
HSDL2 hydroxysteroid dehydrogenase like 2
IGF1R insulin-like growth factor 1 receptor
IGSF3 immunoglobulin superfamily, member 3
IPO11 importin 11
IQGAP1 IQ motif containing GTPase activating protein 1
ITPKB inositol-trisphosphate 3-kinase B
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KAT6B K(lysine) acetyltransferase 6B
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNQ1DN KCNQ1 downstream neighbor (non-protein coding)
KDM6A lysine (K)-specific demethylase 6A
KGFLP2 keratinocyte growth factor-like protein 2
KIAA0368 KIAA0368
KIAA2018 KIAA2018
KIF21A kinesin family member 21A
KIF2A kinesin heavy chain member 2A
KLHL21 kelch-like family member 21
KPNA1 karyopherin alpha 1 (importin alpha 5)
KRTAP10-11 keratin associated protein 10-11
KRTAP19-7 keratin associated protein 19-7
KRTAP20-2 keratin associated protein 20-2
KRTAP4-8 keratin associated protein 4-8
KRTAP5-6 keratin associated protein 5-6
LCMT2 leucine carboxyl methyltransferase 2
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LHX2 LIM homeobox 2
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC57 leucine rich repeat containing 57
LRRC8A leucine rich repeat containing 8 family, member A
LUZP1 leucine zipper protein 1
LYPD6 LY6/PLAUR domain containing 6
MAP1A microtubule-associated protein 1A
MAP1B microtubule-associated protein 1B
MAP2K3 mitogen-activated protein kinase kinase 3
MAPKBP1 mitogen-activated protein kinase binding protein 1
MCM2 minichromosome maintenance complex component 2
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MKNK1 MAP kinase interacting serine/threonine kinase 1
MOB3C MOB kinase activator 3C
MRPS27 mitochondrial ribosomal protein S27
MSL2 male-specific lethal 2 homolog (Drosophila)
MYO5A myosin VA (heavy chain 12, myoxin)
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NATD1 N-acetyltransferase domain containing 1
NCS1 neuronal calcium sensor 1
NELFB negative elongation factor complex member B
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NHSL1 NHS-like 1
NMUR2 neuromedin U receptor 2
NPFFR1 neuropeptide FF receptor 1
NPNT nephronectin
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16
NUP188 nucleoporin 188kDa
NUP214 nucleoporin 214kDa
NUP98 nucleoporin 98kDa
OIP5 Opa interacting protein 5
OR10J3 olfactory receptor, family 10, subfamily J, member 3
OR5D18 olfactory receptor, family 5, subfamily D, member 18
OR5L1 olfactory receptor, family 5, subfamily L, member 1 (gene/pseudogene)
OR7D2 olfactory receptor, family 7, subfamily D, member 2
OSTF1 osteoclast stimulating factor 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PALLD palladin, cytoskeletal associated protein
PARD6G par-6 family cell polarity regulator gamma
PCDHGA10 protocadherin gamma subfamily A, 10
PCDHGC4 protocadherin gamma subfamily C, 4
PCNT pericentrin
PCSK5 proprotein convertase subtilisin/kexin type 5
PHF13 PHD finger protein 13
PHF2 PHD finger protein 2
PHLDB2 pleckstrin homology-like domain, family B, member 2
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PKP1 plakophilin 1
PLA2R1 phospholipase A2 receptor 1, 180kDa
PLCXD2 phosphatidylinositol-specific phospholipase C, X domain containing 2
PLEC plectin
POF1B premature ovarian failure, 1B
POMZP3 POM121 and ZP3 fusion
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRC1 protein regulator of cytokinesis 1
PRDM10 PR domain containing 10
PRPF4 pre-mRNA processing factor 4
PRRC2B proline-rich coiled-coil 2B
PTCD2 pentatricopeptide repeat domain 2
PTGFRN prostaglandin F2 receptor inhibitor
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PYGO1 pygopus family PHD finger 1
RAB14 RAB14, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RABL3 RAB, member of RAS oncogene family-like 3
RABL6 RAB, member RAS oncogene family-like 6
RAD23B RAD23 homolog B (S. cerevisiae)
RAET1L retinoic acid early transcript 1L
RASEF RAS and EF-hand domain containing
RC3H2 ring finger and CCCH-type domains 2
RNF111 ring finger protein 111
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RORA RAR-related orphan receptor A
RPAP1 RNA polymerase II associated protein 1
RPL13AP17 ribosomal protein L13a pseudogene 17
RRM1 ribonucleotide reductase M1
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEPN1 selenoprotein N, 1
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
SETX senataxin
SGPL1 sphingosine-1-phosphate lyase 1
SGPP2 sphingosine-1-phosphate phosphatase 2
SH3RF1 SH3 domain containing ring finger 1
SIN3A SIN3 transcription regulator family member A
SLC22A14 solute carrier family 22, member 14
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
SLC35A5 solute carrier family 35, member A5
SLC41A3 solute carrier family 41, member 3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
SLC9C1 solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SMC1A structural maintenance of chromosomes 1A
SMC2 structural maintenance of chromosomes 2
SMC5 structural maintenance of chromosomes 5
SNORA66 small nucleolar RNA, H/ACA box 66
SNORA84 small nucleolar RNA, H/ACA box 84
SNORD115-7 small nucleolar RNA, C/D box 115-7
SOGA1 suppressor of glucose, autophagy associated 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOSTDC1 sclerostin domain containing 1
SP1 Sp1 transcription factor
SP2 Sp2 transcription factor
SPATA19 spermatogenesis associated 19
SPG11 spastic paraplegia 11 (autosomal recessive)
SPIN1 spindlin 1
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
STAG1 stromal antigen 1
STK40 serine/threonine kinase 40
STOX2 storkhead box 2
STPG1 sperm-tail PG-rich repeat containing 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYCP1 synaptonemal complex protein 1
SYK spleen tyrosine kinase
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TCF19 transcription factor 19
TCTEX1D2 Tctex1 domain containing 2
TET2 tet methylcytosine dioxygenase 2
TGFBR3 transforming growth factor, beta receptor III
TGIF2LX TGFB-induced factor homeobox 2-like, X-linked
THSD7B thrombospondin, type I, domain containing 7B
TJP2 tight junction protein 2
TLE4 transducin-like enhancer of split 4
TLN2 talin 2
TMEM11 transmembrane protein 11
TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough
TMEM201 transmembrane protein 201
TMEM245 transmembrane protein 245
TMEM246 transmembrane protein 246
TOR1A torsin family 1, member A (torsin A)
TOR4A torsin family 4, member A
TP53BP1 tumor protein p53 binding protein 1
TPPP2 tubulin polymerization-promoting protein family member 2
TRAK1 trafficking protein, kinesin binding 1
TRIM14 tripartite motif containing 14
TRIM29 tripartite motif containing 29
TRIM32 tripartite motif containing 32
TRIM35 tripartite motif containing 35
TSPAN18 tetraspanin 18
TSSK1B testis-specific serine kinase 1B
TTBK2 tau tubulin kinase 2
TUBGCP4 tubulin, gamma complex associated protein 4
TXLNA taxilin alpha
TYRO3 TYRO3 protein tyrosine kinase
UBQLN1 ubiquilin 1
UCK1 uridine-cytidine kinase 1
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
ULBP2 UL16 binding protein 2
ULBP3 UL16 binding protein 3
UPK1B uroplakin 1B
USP22 ubiquitin specific peptidase 22
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR76 WD repeat domain 76
WEE1 WEE1 G2 checkpoint kinase
WNK2 WNK lysine deficient protein kinase 2
WWTR1 WW domain containing transcription regulator 1
XPA xeroderma pigmentosum, complementation group A
ZBTB22 zinc finger and BTB domain containing 22
ZBTB34 zinc finger and BTB domain containing 34
ZER1 zyg-11 related, cell cycle regulator
ZNF148 zinc finger protein 148
ZNF367 zinc finger protein 367
ZNF407 zinc finger protein 407
ZNF462 zinc finger protein 462
ZNF592 zinc finger protein 592
ZNF609 zinc finger protein 609
ZXDC ZXD family zinc finger C

low expression

Symbol Name
ATAD1 ATPase family, AAA domain containing 1
OXSR1 oxidative stress responsive 1