Lung squamous cell carcinoma_LUSC_TCGA-60-2697-01A-11R-2125-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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Genes

432 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-60-2697-01A-11R-2125-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ABRA actin binding Rho activating protein
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACOX2 acyl-CoA oxidase 2, branched chain
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADAM6 ADAM metallopeptidase domain 6 (pseudogene)
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADGRG5 adhesion G protein-coupled receptor G5
ADGRL4 adhesion G protein-coupled receptor L4
ADRA2A adrenoceptor alpha 2A
AGBL1 ATP/GTP binding protein-like 1
AKNA AT-hook transcription factor
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2
ALPL alkaline phosphatase, liver/bone/kidney
AMY1A amylase, alpha 1A (salivary)
AMY2A amylase, alpha 2A (pancreatic)
AMY2B amylase, alpha 2B (pancreatic)
ANGPTL6 angiopoietin-like 6
ANK2 ankyrin 2, neuronal
ANKDD1A ankyrin repeat and death domain containing 1A
ANKRD44 ankyrin repeat domain 44
ANKRD55 ankyrin repeat domain 55
ANXA6 annexin A6
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APLNR apelin receptor
ARHGAP15 Rho GTPase activating protein 15
ARHGAP25 Rho GTPase activating protein 25
ARHGAP30 Rho GTPase activating protein 30
ARHGAP9 Rho GTPase activating protein 9
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARR3 arrestin 3, retinal (X-arrestin)
ATM ATM serine/threonine kinase
ATP10B ATPase, class V, type 10B
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
BANK1 B-cell scaffold protein with ankyrin repeats 1
BATF basic leucine zipper transcription factor, ATF-like
BFSP2 beaded filament structural protein 2, phakinin
BHLHA15 basic helix-loop-helix family, member a15
BHLHE22 basic helix-loop-helix family, member e22
BIN2 bridging integrator 2
BLK BLK proto-oncogene, Src family tyrosine kinase
BMX BMX non-receptor tyrosine kinase
BPI bactericidal/permeability-increasing protein
BTBD9 BTB (POZ) domain containing 9
BTK Bruton agammaglobulinemia tyrosine kinase
BTLA B and T lymphocyte associated
BTN3A2 butyrophilin, subfamily 3, member A2
C16ORF78 chromosome 16 open reading frame 78
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
C4BPA complement component 4 binding protein, alpha
C6ORF222 chromosome 6 open reading frame 222
C7 complement component 7
C8ORF34 chromosome 8 open reading frame 34
CACHD1 cache domain containing 1
CADM3 cell adhesion molecule 3
CARD8 caspase recruitment domain family, member 8
CCDC129 coiled-coil domain containing 129
CCDC69 coiled-coil domain containing 69
CCL14 chemokine (C-C motif) ligand 14
CCR4 chemokine (C-C motif) receptor 4
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CD180 CD180 molecule
CD19 CD19 molecule
CD1C CD1c molecule
CD226 CD226 molecule
CD247 CD247 molecule
CD27 CD27 molecule
CD28 CD28 molecule
CD37 CD37 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD40LG CD40 ligand
CD48 CD48 molecule
CD5 CD5 molecule
CD6 CD6 molecule
CD7 CD7 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CD96 CD96 molecule
CDRT15 CMT1A duplicated region transcript 15
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CERKL ceramide kinase-like
CETP cholesteryl ester transfer protein, plasma
CFAP221 cilia and flagella associated protein 221
CFI complement factor I
CHD1 chromodomain helicase DNA binding protein 1
CHMP7 charged multivesicular body protein 7
CHRDL2 chordin-like 2
CISH cytokine inducible SH2-containing protein
CLEC3A C-type lectin domain family 3, member A
CLEC9A C-type lectin domain family 9, member A
CLECL1 C-type lectin-like 1
CLK4 CDC-like kinase 4
CLNK cytokine-dependent hematopoietic cell linker
CLU clusterin
CMA1 chymase 1, mast cell
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CNOT6L CCR4-NOT transcription complex, subunit 6-like
CNR2 cannabinoid receptor 2 (macrophage)
CORO1A coronin, actin binding protein, 1A
CPNE5 copine V
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CREM cAMP responsive element modulator
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRTAC1 cartilage acidic protein 1
CSNK1G2-AS1 CSNK1G2 antisense RNA 1
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CTC1 CTS telomere maintenance complex component 1
CTSE cathepsin E
CTSG cathepsin G
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR5 chemokine (C-X-C motif) receptor 5
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYLD cylindromatosis (turban tumor syndrome)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYSLTR1 cysteinyl leukotriene receptor 1
CYTIP cytohesin 1 interacting protein
DEFB109P1B defensin, beta 109, pseudogene 1B
DENND1C DENN/MADD domain containing 1C
DENND2D DENN/MADD domain containing 2D
DENND5B DENN/MADD domain containing 5B
DERL3 derlin 3
DLL4 delta-like 4 (Drosophila)
DOCK10 dedicator of cytokinesis 10
DOCK2 dedicator of cytokinesis 2
DOCK8 dedicator of cytokinesis 8
DPF3 D4, zinc and double PHD fingers, family 3
EBF1 early B-cell factor 1
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPB41 erythrocyte membrane protein band 4.1
ERN1 endoplasmic reticulum to nucleus signaling 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EVI2B ecotropic viral integration site 2B
EXOC3L2 exocyst complex component 3-like 2
FAM107B family with sequence similarity 107, member B
FAM110D family with sequence similarity 110, member D
FAM159A family with sequence similarity 159, member A
FAM167B family with sequence similarity 167, member B
FAM209A family with sequence similarity 209, member A
FAM20A family with sequence similarity 20, member A
FAM46C family with sequence similarity 46, member C
FAM65B family with sequence similarity 65, member B
FBXO2 F-box protein 2
FCMR Fc fragment of IgM receptor
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FCRL3 Fc receptor-like 3
FCRL4 Fc receptor-like 4
FCRL5 Fc receptor-like 5
FCRLA Fc receptor-like A
FGF7 fibroblast growth factor 7
FICD FIC domain containing
FKBP11 FK506 binding protein 11, 19 kDa
FLRT3 fibronectin leucine rich transmembrane protein 3
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FMNL1 formin-like 1
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FYB FYN binding protein
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6
GAPT GRB2-binding adaptor protein, transmembrane
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GIMAP7 GTPase, IMAP family member 7
GJA4 gap junction protein, alpha 4, 37kDa
GMPPB GDP-mannose pyrophosphorylase B
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPR132 G protein-coupled receptor 132
GPR171 G protein-coupled receptor 171
GPR174 G protein-coupled receptor 174
GPR18 G protein-coupled receptor 18
GPR55 G protein-coupled receptor 55
GPR82 G protein-coupled receptor 82
GPSM3 G-protein signaling modulator 3
GRAMD1B GRAM domain containing 1B
GRAP2 GRB2-related adaptor protein 2
GRAPL GRB2-related adaptor protein-like
GTSF1L gametocyte specific factor 1-like
GVINP1 GTPase, very large interferon inducible pseudogene 1
GZMK granzyme K (granzyme 3; tryptase II)
HAS1 hyaluronan synthase 1
HCG26 HLA complex group 26 (non-protein coding)
HCRT hypocretin (orexin) neuropeptide precursor
HDC histidine decarboxylase
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIGD1C HIG1 hypoxia inducible domain family, member 1C
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DOB major histocompatibility complex, class II, DO beta
HMCN1 hemicentin 1
HP haptoglobin
HSH2D hematopoietic SH2 domain containing
ICAM3 intercellular adhesion molecule 3
IFITM2 interferon induced transmembrane protein 2
IGFBP4 insulin-like growth factor binding protein 4
IGFLR1 IGF-like family receptor 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IKZF4 IKAROS family zinc finger 4 (Eos)
IL16 interleukin 16
IL1R1 interleukin 1 receptor, type I
IL22RA2 interleukin 22 receptor, alpha 2
IL2RG interleukin 2 receptor, gamma
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IPCEF1 interaction protein for cytohesin exchange factors 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAD integrin, alpha D
ITGB7 integrin, beta 7
ITK IL2-inducible T-cell kinase
JAK3 Janus kinase 3
JCHAIN joining chain of multimeric IgA and IgM
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDM5D lysine (K)-specific demethylase 5D
KIAA0125 KIAA0125
KIAA1551 KIAA1551
KIF21B kinesin family member 21B
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LAT linker for activation of T cells
LAX1 lymphocyte transmembrane adaptor 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LGALS12 lectin, galactoside-binding, soluble, 12
LGALS2 lectin, galactoside-binding, soluble, 2
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LINC00264 long intergenic non-protein coding RNA 264
LINC00593 long intergenic non-protein coding RNA 593
LIPG lipase, endothelial
LOC100130264 uncharacterized LOC100130264
LOC145474 uncharacterized LOC145474
LOC606724 coronin, actin binding protein, 1A pseudogene
LOC728989 phosphodiesterase 4D interacting protein pseudogene
LRRC52 leucine rich repeat containing 52
LRRC70 leucine rich repeat containing 70
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
LTF lactotransferrin
LY9 lymphocyte antigen 9
MACROD2 MACRO domain containing 2
MANF mesencephalic astrocyte-derived neurotrophic factor
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MEDAG mesenteric estrogen-dependent adipogenesis
MEF2C myocyte enhancer factor 2C
MEI1 meiosis inhibitor 1
MILR1 mast cell immunoglobulin-like receptor 1
MIR155HG MIR155 host gene
MROH2B maestro heat-like repeat family member 2B
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MUSK muscle, skeletal, receptor tyrosine kinase
MYBPC2 myosin binding protein C, fast type
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAPSB napsin B aspartic peptidase, pseudogene
NCF4 neutrophil cytosolic factor 4, 40kDa
NCOA7 nuclear receptor coactivator 7
NCR3 natural cytotoxicity triggering receptor 3
NECAB1 N-terminal EF-hand calcium binding protein 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NLRC3 NLR family, CARD domain containing 3
NLRP6 NLR family, pyrin domain containing 6
NNMT nicotinamide N-methyltransferase
NOD1 nucleotide-binding oligomerization domain containing 1
NPY4R neuropeptide Y receptor Y4
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRGN neurogranin (protein kinase C substrate, RC3)
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
OR13J1 olfactory receptor, family 13, subfamily J, member 1
OR2A14 olfactory receptor, family 2, subfamily A, member 14
OR2T33 olfactory receptor, family 2, subfamily T, member 33
OR56B1 olfactory receptor, family 56, subfamily B, member 1
ORM1 orosomucoid 1
ORM2 orosomucoid 2
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
P2RY8 purinergic receptor P2Y, G-protein coupled, 8
PARP15 poly (ADP-ribose) polymerase family, member 15
PDCD1 programmed cell death 1
PDE4D phosphodiesterase 4D, cAMP-specific
PHF23 PHD finger protein 23
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase
PI15 peptidase inhibitor 15
PI16 peptidase inhibitor 16
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G2C phospholipase A2, group IIC
PLA2G2D phospholipase A2, group IID
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLCL2 phospholipase C-like 2
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3
PLIN5 perilipin 5
PLVAP plasmalemma vesicle associated protein
PMP22 peripheral myelin protein 22
POU2AF1 POU class 2 associating factor 1
POU2F2 POU class 2 homeobox 2
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRAMEF5 PRAME family member 5
PRKCB protein kinase C, beta
PROX2 prospero homeobox 2
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PVRIG poliovirus receptor related immunoglobulin domain containing
PYHIN1 pyrin and HIN domain family, member 1
RAB27A RAB27A, member RAS oncogene family
RAB33A RAB33A, member RAS oncogene family
RAB37 RAB37, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RASA3 RAS p21 protein activator 3
RASAL3 RAS protein activator like 3
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBP5 retinol binding protein 5, cellular
RBPMS RNA binding protein with multiple splicing
RCSD1 RCSD domain containing 1
REN renin
RGL4 ral guanine nucleotide dissociation stimulator-like 4
RGS16 regulator of G-protein signaling 16
RHD Rh blood group, D antigen
RHOH ras homolog family member H
RND1 Rho family GTPase 1
RNF151 ring finger protein 151
RNF5P1 ring finger protein 5, E3 ubiquitin protein ligase pseudogene 1
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RRN3P2 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 2
RTN4RL1 reticulon 4 receptor-like 1
SAA1 serum amyloid A1
SAA2 serum amyloid A2
SAA4 serum amyloid A4, constitutive
SAMD3 sterile alpha motif domain containing 3
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SASH3 SAM and SH3 domain containing 3
SATB1 SATB homeobox 1
SCML4 sex comb on midleg-like 4 (Drosophila)
SCTR secretin receptor
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SELE selectin E
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SEPT1 septin 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFTPB surfactant protein B
SH2D1A SH2 domain containing 1A
SH3KBP1 SH3-domain kinase binding protein 1
SIAE sialic acid acetylesterase
SIGLEC17P sialic acid binding Ig-like lectin 17, pseudogene
SIRPG signal-regulatory protein gamma
SLAMF1 signaling lymphocytic activation molecule family member 1
SLAMF6 SLAM family member 6
SLAMF7 SLAM family member 7
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
SLFN12L schlafen family member 12-like
SMAP2 small ArfGAP2
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNAI1 snail family zinc finger 1
SNAI3 snail family zinc finger 3
SNORA61 small nucleolar RNA, H/ACA box 61
SNORA71B small nucleolar RNA, H/ACA box 71B
SNX20 sorting nexin 20
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOD2 superoxide dismutase 2, mitochondrial
SP140 SP140 nuclear body protein
SPACA3 sperm acrosome associated 3
SPNS3 spinster homolog 3 (Drosophila)
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STC1 stanniocalcin 1
STEAP4 STEAP family member 4
STK10 serine/threonine kinase 10
STK4 serine/threonine kinase 4
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SYT15 synaptotagmin XV
TAOK3 TAO kinase 3
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TESPA1 thymocyte expressed, positive selection associated 1
TIGIT T cell immunoreceptor with Ig and ITIM domains
TLR9 toll-like receptor 9
TMEM213 transmembrane protein 213
TMEM255B transmembrane protein 255B
TMTC2 transmembrane and tetratricopeptide repeat containing 2
TNFAIP8L3 tumor necrosis factor, alpha-induced protein 8-like 3
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNIP3 TNFAIP3 interacting protein 3
TP53INP1 tumor protein p53 inducible nuclear protein 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRAF3IP3 TRAF3 interacting protein 3
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRAT1 T cell receptor associated transmembrane adaptor 1
TXK TXK tyrosine kinase
TXNDC11 thioredoxin domain containing 11
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
UBASH3A ubiquitin associated and SH3 domain containing A
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UGCG UDP-glucose ceramide glucosyltransferase
ULK4 unc-51 like kinase 4
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
WAS Wiskott-Aldrich syndrome
WDFY4 WDFY family member 4
WDR64 WD repeat domain 64
WFDC8 WAP four-disulfide core domain 8
WIPF1 WAS/WASL interacting protein family, member 1
XBP1 X-box binding protein 1
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBP1 Z-DNA binding protein 1
ZBTB32 zinc finger and BTB domain containing 32
ZNF154 zinc finger protein 154
ZNF385D zinc finger protein 385D
ZNF80 zinc finger protein 80
ZNF831 zinc finger protein 831
ZNF99 zinc finger protein 99